• Journal of Korean Tunnelling and Underground Space Association
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• v.12 no.6
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• pp.463-473
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• 2010

A new approach for prediction of a fault zone ahead of tunnel face by using statistical control charts is suggested and applied to the construction site. $x-R_s$ control charts of RMR parameters were investigated as approaching and passing through fault zone. The abnormal signal from the control charts was observed and analyzed based on statistical criteria. Fault zones in the application area were predicted in advance using this method and it was verified by comparing with observation data like horizontal boring and face mapping.

• Journal of Periodontal and Implant Science
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• v.28 no.4
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• pp.691-703
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• 1998

The 16S rRNA analyzing method is a bacterial identification method that is useful in identifying bacteria which is difficult to do by other means. The following 7 types of bacteria which are Treponema, A. actinomycetemcomitans, P. gingivalis, Fusobacterium, B. forsythus, P. intermedia, P. micros were evaluated in order to study their distribution among patients with adult periodontitis. The 16S rRNA analyzing method was used to compare bacterial distribution among 3 groups. Subgingival plaque acquired from the affected sites(pocket depth ${\geq}6mm$) of 29 patients with adult periodontitis were grouped as the experimental group while plaque from the non-affected sites(pocket depth ${\leq}3mm$) were grouped as control 2 and finally plaque acquired from students with healthy periodontal tissues were grouped as control 1. The results are as follows ; 1. The distribution of Treponema was 12.5% for control 1, 21.4% for control 2 and 75.4% for the experimental group. For A. actinomycetemcomitans the distribution was 0.5%, 19.0%, 44.4% in respect to the order of groups mentioned above. P.gingivalis showed 10.5%, 43.1%, 94.0% distribution, Fusobacterium 33.0%, 48.3%, 81.0% distribution, B. forsythus 9.5%, 17.2%, 65.9% distribution, P. intermedia 1.0%, 12.1%, 26.3% distribution and finally P. micros 5.0%, 19.0%, 48.7% respectively. In all 7 types of bacteria, the experimental group showed higher bacterial distribution compared to the other two groups with statistically significant difference. 2. In the case of Treponema, A. actinomycetemcomitans, gingivalis,Fusobacterium, B. forsythus, P. intermedia, P. micros showed significant difference between control 1 and 2. These results suggest that the 16S rRNA analyzing method which was applied on Koreans for the first time could be utilized and useful in finding potential pathogens of periodontal disease.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.1 no.2
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• pp.33-38
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• 2008

The baseline wander of ECG makes difficult to detect P-, Q-, R- and S-wave. This paper presents and compares two method to remove the baseline wander of ECG using slope traceing waves. For the first method that had been proposed already[1], the ascending slope tracing method is used to eliminate baseline wander. And the second method employs the contour of the approximated S-wave to remove baseline wander. These two methods are common to use the slope tracing wave. However, the first one is to get difference signals between the ascending tracing waves and ECG signals, and the other is to remove baseline wander using the contour of the approximated S-wave obtained from descending slope waves. To evaluate these methods, we apply to MIT/BIH database.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.6 no.2
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• pp.75-91
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• 2020

[^99mTc]Tc-Hexamethylpropylene amine oxime (HMPAO) is currently used as a regional cerebral blood flow imaging agent for single photon emission computed tomography (SPECT). The HMPAO ligand exists in two isomeric forms: d,l and meso showing different properties in vivo. Later studies indicated that brain uptake patterns of ^99mTc-complexes formed from separated enantiomers differed. Separation of enantiomers is difficult by fractional crystallizations method. Usually, the substance is obtained in low chemical yield in a time-consuming procedure. Furthermore, the final product still contains some impurity. So we have developed new efficient route for synthesis of R,R- and S,S-HMPAO enantiomeric compounds in 6-steps. Nucleophilic substitution (S_N2) reactions of 2,2-dimethylpropane-1,3-diamine either with S- (1a) or R-methyl2-chloropropanoate (1b) were performed to produce compounds R,R- (2a) or S,S-isomer (2b) derivatives protected with benzylchloroformate (Cbz), respectively. And then Weinreb amide and methylation reaction using Grignard reagent, oxime formation with ketone group and deprotectiion of Cbz group by hydrogenolysis gave S,S- (7a) or R,R-HMPAO (7b), respectively. Entaniomeric compounds were synthesied with high yield and purity without any undesired product. The 7a or 7b kits containing 10 ㎍ SnCl₂-2H₂O were labeled with ^99mTc with high radiolabeling yield (90%).

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.131-136
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• 2003

CF8M cast austenitic stainless steel is used for several components such as primary coolant piping, elbow, pump casing, and valve bodies in light water reactors. These components are subject to thermal aging at the reactor operating temperature. Thermal aging results in spinodal decomposition of the delta-ferrite leading to increased strength and decreased toughness. In this study, three kinds of the aged CF8M specimen were prepared using an artificially simulated aging method. The objective of this study is to summarize the method of estimating ferrite contents, Charpy impact energy and J-R curve, and to evaluate the thermal embrittlement of the CF8M cast austenitic stainless steel piping used in the domestic nuclear power plants.

• The Korean Journal of Zoology
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• v.37 no.3
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• pp.343-351
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• 1994

The partial nucleotide sequences of 185 ribosomal RNA gene were compared for six cnidarian species (one belongs to class Hvdrozoa: Coryne pusilla. Five belong to class Anthozoa: Beflonella rigida from Octocorallia; Anemonia sulcutu, Anthopfeura kurognne, An thopleura midori from Hexacorallia: Cerianthus filiformis from Ceriantipatharial. The aligned sequence data were used to test the hypothesis on the anthozoan phylosenv by using the distance matrix method and parsimony method. The phvlosenetic inferences resulting from these methods indicate that the anthozoan is a monophvletic group and support the three subclass scheme (Octocorallia, HexBcorallia, Ceriantipatharial within class Anthozoa. The result also indicates that ceriantipatharian is more primitive than the other groups and that family Actiniidae is a monophvletic group within the anthozoan. However, the present analysis does not clearly indicate the phvlogenetic relationships of species among genera.

• Proceedings of the Korea Technology Innovation Society Conference
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• 2001.05a
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• pp.369-385
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• 2001

A R&D project evaluation method has been applied for the national nuclear R&D projects in a developing-country setting. In the methodology, Saaty's analytic hierarchy process model is used to evaluate and rank of the selected nuclear R&D project which have a wide range of objectives and characteristics. The criteria used for evaluation related specifically to the Korea's evaluation needs and culture, and they are weighted according to their relative importance as perceived by the evaluator of the R&D project. As a real-world case of evaluation, we elicited and reproduced the evaluation process of the nuclear R&D projects which is going under the research process. As the results of the paper suggests, the methodology can be applied to the evaluation of the R&D projects and has much potential.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.13 no.3
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• pp.103-109
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• 2013

Miller-Rabin method is the most prevalently used primality test. However, this method mistakenly reports a Carmichael number or semi-prime number as prime (strong lier) although they are composite numbers. To eradicate this problem, it selects k number of m, whose value satisfies the following : m=[2,n-1], (m,n)=1. The Miller-Rabin method determines that a given number is prime, given that after the computation of $n-1=2^sd$, $0{\leq}r{\leq}s-1$, the outcome satisfies $m^d{\equiv}1$(mod n) or $m^{2^rd}{\equiv}-1$(mod n). This paper proposes a step-by-step primality testing algorithm that restricts m=2, hence achieving 98.8% probability. The proposed method, as a first step, rejects composite numbers that do not satisfy the equation, $n=6k{\pm}1$, $n_1{\neq}5$. Next, it determines prime by computing $2^{2^{s-1}d}{\equiv}{\beta}_{s-1}$(mod n) and $2^d{\equiv}{\beta}_0$(mod n). In the third step, it tests ${\beta}_r{\equiv}-1$ in the range of $1{\leq}r{\leq}s-2$ for ${\beta}_0$ > 1. In the case of ${\beta}_0$ = 1, it retests m=3,5,7,11,13,17 sequentially. When applied to n=[101,1000], the proposed algorithm determined 96.55% of prime in the initial stage. The remaining 3% was performed for ${\beta}_0$ >1 and 0.55% for ${\beta}_0$ = 1.

• The Journal of Natural Sciences
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• v.18 no.1
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• pp.47-53
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• 2007

In order to find novel sRNA in Bacillus subtilis which would be used to adapt to several conditions, we searched the whole genome of Bacillus subtilis using the following procedure. At first, the locations of recognition sequence of transcription factors such as PerR, OhrR, Fur and Zur were searched in the intergenic region of Bacillus subtilis genome and the locations of rho independent transcription terminator sites were also determined. Based on the information of these locations, the sRNA candidates were chosen by close locations (less than 300 bp) between the recognition site of transcription factors and rho independent transcription terminator site. Than transcription promoter sites were searched in the region of previously identified sRNA candidates and 5 PerR, 1 OhrR, 1 Fur and 1 Zur regulated good sRNA candidates were found.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2007.11a
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• pp.237-238
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• 2007