• 제목/요약/키워드: R&D Centers

검색결과 136건 처리시간 0.031초

델파이기법을 활용한 국가 공공(公共)백신 연구개발 정책수립 기초조사 (A Delphi Study on National Public Vaccine Research and Development Policy in Korea)

  • 이소민;여상구;강신정;한순영;이상원
    • 보건행정학회지
    • /
    • 제25권2호
    • /
    • pp.140-148
    • /
    • 2015
  • Vaccination is the most powerful and useful preparation against infectious diseases. However, developing vaccines costs a lot and requires extensive long-term efforts. Therefore, the government should research and develop vaccines with a national-level policy. To greatly enhance the success rate of vaccine development, the policy should be set up considering priorities such as the current status of domestic research, the importance for public health, the urgency of research. The Delphi technique was utilized to draft this survey, through a brainstorming stage, then two inquiries, and finally the final panel meeting where unresolved items were discussed, to draw the conclusion. Among the results, firstly, the highest ranked item on centralized fields for vaccine development by the Ministry of Health was 'self-sufficiency of vaccines.' Secondly, 'emerging infectious disease' was most highly ranked in prioritized fields of vaccine development and research. Thirdly, for the vaccine that needs to be improved and developed further by the government to improve its efficacy and safety, BCG (Bacille de Calmette) for tuberculosis was ranked the highest on both types (intradermal and subcutaneous injection) from National Immunization Programme (NIP) and non-NIP. As for the high risk pathogens, 'anthrax' and 'smallpox' were first and second, consecutively. Lastly, 'development and control of vaccine candidates' was ranked the highest for the area in need for technique development in order to improve domestic vaccine's research level. The results of this study will be put to good use as basic data for the national vaccine research and development (R&D) policy of the country. This study was first step and more studies should be carried out for the final decision of the national vaccine R&D priority.

서울지역 공공청사 민원실의 겨울철 실내공기질에 관한 연구 (Study on Indoor Air Pollutants of Public Service Centers in Winter, Seoul)

  • 전재식;김미형;이주열;전명진;류인철;박덕신;최한영
    • 한국대기환경학회지
    • /
    • 제27권5호
    • /
    • pp.569-579
    • /
    • 2011
  • This study evaluated the indoor air quality of 26 government offices located in Seoul. The pollutant samples were taken from Jan. 13th to Jan. 29th and Feb. 20th to Feb. 23rd, 2010 in the offices. The target indoor pollutants for this study were $PM_{10}$, formaldehyde, carbon monoxide, carbon dioxide, total bacteria counts, total volatile organic compounds, radon, nitrogen dioxide, ozone, and asbestos which were controlled by the indoor air quality law for the multiple-use facilities management. The results of this study showed that some pollutants of the 38.5% offices exceeded the standards of the air quality guideline. The correlation analysis of the same pollutants between indoor and outdoor represented that $NO_2$ (r=0.629, p<0.05) and $O_3$ (r=0.459, p<0.01) were significant, however, $PM_{10}$ and CO were not. The correlation analysis between different pollutants showed that CO and TVOC (total volatile organic compounds: r=0.724; p<0.01), CO and $NO_2$ (r=0.674; p<0.01), HCHO and humidity (r=0.605; p<0.01), $CO_2$ and TVOC (r=0.534; p<0.01), TBC (total bacteria counts) and Asbestos (r=0.520; p<0.01) were significant. The energy-saving system of government buildings in winter caused under-ventilated and poor air quality. This study suggests that the concentrations of radon and $CO_2$ should be used as an indicator for monitoring indoor air quality and maintaining effective ventilations.

어린이 활동양상 설문분석을 통한 신규관리 활동공간 검토 (Selection of New High-maintenance Children's Activity Spaces based on Children's Life Patterns)

  • 김호현;최인석;남의현;이정훈;유시은;박충희;이정섭
    • 한국환경보건학회지
    • /
    • 제45권2호
    • /
    • pp.164-172
    • /
    • 2019
  • Objectives: This study's purpose is finding children's activity spaces that demand environmental safety management. Methods: The method of this study is analysing children's life patterns based on a questionnaire survey. Results: This study analyzed children's life patterns through a questionnaire survey. In total, 2,447 questionnaires were provided to analyze children's life patterns. The results of the questionnaire indicated a highly simple form because many children generally stayed in their home (66%) or nursery facility (2%). In the case of other facilities, playground was ranked first and amusement park was ranked second. In addition, kids cafe (including play facilities installed in shopping centers, etc.), library, and internet cafe were among the responses. Conclusions: The priority for new high-maintenance children's activity spaces are academy (rank 1), kids cafe (rank 2), indoor playground (rank 3).

유한한 기판 크기가 H-평면상에 배열된 두 개의 패치안테나간의 상호결합에 미치는 영향 (Effect of a Finite Substrate on the Mutual Coupling of a Pair of Microstrip Patch Antennas along the H-plane)

  • 김군수;김태영;김부균
    • 대한전자공학회논문지TC
    • /
    • 제47권10호
    • /
    • pp.67-73
    • /
    • 2010
  • 유한한 기판 크기가 H-평면상에 배열된 두 개의 패치안테나간의 상호결합 특성에 미치는 영향에 대하여 연구하였다. 표면파의 여러 가지 이동경로에 따른 위상차에 의한 간섭 효과를 이용하여 표면파를 서로 상쇄시켜 상호결합을 작게 할 수 있다. 유전상수가 10 이고 기판 두께가 3.2 mm 인 경우 패치안테나 중심 간의 거리가 0.5 $_0$에서 1.0 $\lambda_0$로 두 배 증가할 때, 상호 결합이 큰 기판 크기에서는 상호결합이 4.85 dB 감소하나 최적화된 기판 크기에서는 상호결합이 34.28 dB 감소한다. 최적화된 기판 크기에서 패치안테나 중심 간의 거리 증가에 따른 상호결합 감소율이 매우 큼을 볼 수 있었다. 이미지 방법으로 계산한 최적화된 기판 크기와 전산모의 결과로 얻어진 최적화된 기판 크기가 잘 일치하였다.

생명공학 기업의 경쟁력 강화를 위한 지식인프라의 효율적 구축방안

  • 정석선;정선양
    • 기술경영경제학회:학술대회논문집
    • /
    • 기술경영경제학회 2002년도 제21회 하계학술발표회 논문집
    • /
    • pp.157-179
    • /
    • 2002
  • Many advanced scholars and policy makers say that biotechnology is and will be the most important technology in 21th century. And biotechnology has a lots of character which are new and high tech industry, costing too much on early R&D stage and so on. One of them is that it can't be developed all seater by one single firm. So effective and efficient way to solve this generic problem is using the infrastructure which is given by government for flourishing the bio industry, especially, Knowledge infrastructure. The purpose of this study is to understand and give the information about which knowledge infrastructure affects biotechnology firms to obtain competitive advantage in technological improvement. To develop this object, I made 5 variables about infrastructure in biotechnology such as high-skilled researchers infrastructure, R&D policy infrastructure, industrialization infrastructure that supports the biotechnology industry, networking infrastructure between firms, universities, research centers, and finally bio-safety infrastructure. According to this study, to obtain technological competitive advantage for Korean bio firms, all main actors those are government, industry, university, research center they try to develop bio sector at the same time. After this cooperated effort, Korean bio firms and industry can get a international competitiveness in the global society which no one conquer the market.

  • PDF

재가 치매노인 배우자의 부양부담감이 구강건강관련 삶의 질에 미치는 영향 (Influence of the Caregiver Burden on the Oral Health-related Quality of Life of the Spouse of an Elderly Person with Dementia at Home)

  • 성기월
    • 한국보건간호학회지
    • /
    • 제34권3호
    • /
    • pp.429-443
    • /
    • 2020
  • Purpose: This study examined the influencing factors of caregiver burden on the oral health-related quality of life of the spouse of an elderly person with dementia at home. Methods: The participants were 115 spouses of dementia patients registered at dementia safety centers in five health centers in D city. Data were collected from June through December in 2019, using questionnaires of Oral Health Impact Profile (OHIP-49) and Burden Interview (BI). The data were analyzed using an independent t-test, one-way ANOVA, Pearson's correlation, and stepwise multiple regression analysis using the IBM SPSS Statistics 25.0 Program. Results: A negative correlation was observed between the oral health-related quality of life and caregiver burden (r=-37, p<.001). The caregiver burden (β=-.28, p=.001), subjective health status (β=.39, p<.001), and dental clinic visit (β=-.25, p=.002) explained 33.0% of the variance in the oral health-related quality of life. Conclusion: The development of nursing care for spouses of dementia patients will be needed to reduce the caregiver burden and enhance subjective health status and dental clinic visit, which influence the oral health-related quality of life of spouse of elderly people with dementia at home.

루비듐 증기로 처리한 탈수한 제올라이트 X의 결정학적 연구 (Crystallographic Studies of Dehydrated Zeolite-X Reacting with Rubidium Vapor)

  • 한영욱
    • 한국광물학회지
    • /
    • 제6권2호
    • /
    • pp.116-121
    • /
    • 1993
  • 제올라이트 $Na_{78}Rb_{28}-X$ 단결정을 $Na_{92}-X(Na_{92}Si_{100}Al_{92}O_{384})$$350^{\circ}C$에서 0.1Torr의 Rb 증기로 처리하여 만들어서 그 구조를 X-선 단결정법으로 공간군 Fd3로서 결정하였다 (${\alpha}=25.045(4){\AA}$). 구조는 I>$3{\sigma}(I)$인 회절반점 353개를 사용하여 최종오차지수 $R_1=0.082$, $R_2=0.084$까지 정밀화하였다. 단위포당 92개의 $Na^+$ 이온 중 대략 28개의 $Na^+$ 이온이 환원되고, 환원되어 생성된 28개의 Na' 중 약 14개만 제올라이트 골조내에 잔류하고 있다. 소다라이트 동공내에 사면체의 대칭성 ($T_d$)을 가지고 결합각 $109.5^{\circ}$, 결합거리 $2.80(2){\AA}$를 갖는다. $Na_5{^{4+}}$ 클라스트를 이루는 4개의 말단 원자와 골조 산소원자 사이의 결합거리는 $2.80(2){\AA}$이다. 몇몇 이중 6-링의 중심에 $Na_5{^{4+}}$ 클라스트 두 개를 선형으로 연결하여 지그재그형의 덩어리로 만드는 $Na^0$원자가 있다. 소다라이트 동공 중심과 이중 6-링에 있는 $Na^0$원자의 비편재화된 전자가 $Na_5{^{4+}}$ 클라스트를 안정화시키고 있다.

  • PDF

사회적 자본으로서 연구인력정보시스템 구축에 관한 탐색적 연구 (A Strategic Approach to the Researcher Information System as Social Capital)

  • 이정연;정연경;정은경
    • 한국문헌정보학회지
    • /
    • 제43권3호
    • /
    • pp.59-84
    • /
    • 2009
  • 인적, 물적 자본에 이어 사회 전체적 맥락에서 공공성을 지닌 부가가치의 창출에 기여하는 사회적 자본이 대두되고 있다. 사회적 자본은 관계적 자본과 사회 정책 실현의 효율성과 정당성을 높이는 사회 전체적 용량을 가지고 있다. 본 연구는 지식정보화 사회에서 국가적인 연구개발 연구인력정보시스템의 네트워크가 사회적 자본으로서 구축될 수 있는 방안에 대하여 살펴보았다. 이를 위해 국가 R&D 과제관리기관, 정부출연연구기관, 정보유통기관에서 연구인력정보시스템의 구축 현황을 살펴보았으며, 연구인력정보시스템 측면에서의 합의와 국가적 차원의 이해당사자 간의 사회적 신뢰 구축과 합의 방안에 대하여 탐색적인 논의를 제시하였다.

Crystal Structure of Fully Dehydrated Partially Cs+-Exchanged Zeolite X, Cs52Na40-X (The Highest Cs+-Exchanged Level Achieved by Conventional Method and Confirmation of Special Site Selectivity)

  • Bae, Myung-Nam
    • Bulletin of the Korean Chemical Society
    • /
    • 제28권2호
    • /
    • pp.251-256
    • /
    • 2007
  • The crystal structure of fully dehydrated partially Cs+-exchanged zeolite X, [Cs52Na40Si100Al92O384], a = 24.9765(10) A, has been determined by single-crystal X-ray diffraction techniques in the cubic space group Fd3 at 21 °C. The crystal was prepared by flow method for 5 days using exchange solution in which mole ratio of CsOH and CsNO3 was 1 : 1 with total concentration of 0.05 M. The crystal was then dehydrated at 400 °C and 2 × 10-6 Torr for 2 days. The structure was refined to the final error indices, R1 = 0.051 and wR2 (based on F2) = 0.094 with 247 reflections for which Fo > 4σ (Fo). In this structure, about fifty-two Cs+ ions per unit cell are located at six different crystallographic sites with special selectivity; about one Cs+ ion is located at site I, at the centers of double oxygen-rings (D6Rs), two Cs+ ions are located at site I', and six Cs+ ions are found at site II'. This is contrary to common view that Cs+ ions cannot pass sodalite cavities nor D6Rs because six-ring entrances are too small. Ring-opening by the formation of ?OH groups and ring-flexing make Cs+ ions at sites I, I', and II' enter six-oxygen rings. The defects of zeolite frameworks also give enough mobility to Cs+ ions to enter sodalite cavities and D6Rs. Another six Cs+ ions are found at site II, thirty-six are located at site III, and one is located at site III' in the supercage, respectively. Forty Na+ ions per unit cell are located at two different crystallographic sites; about fourteen are located at site I, the centers of D6Rs and twenty-six are also located at site II in the supercage. Cs+ ions and Na+ ions at site II are recessed ca. 0.34(1) A and 1.91(1) A into the supercage, respectively. In this work, the highest exchange level of Cs+ ions per unit cell was achieved in zeolite X by conventional aqueous solution methods and it was also shown that Cs+ ion could pass through the sixoxygen rings.

동남아시아 결혼이주여성 임부의 생활 스트레스, 사회적 지지 및 산전우울과의 관계 (Life Stress, Social Support, and Antepartum Depression among Married Immigrant Women from Southeast Asia)

  • 신현희;신영희
    • 지역사회간호학회지
    • /
    • 제26권2호
    • /
    • pp.108-118
    • /
    • 2015
  • Purpose: The purpose of this study was to investigate life stress, social support, and antepartum depression among Southeast Asian immigrant women married to Korean men. Methods: Ninety-three subjects were recruited from local women's clinics and multicultural family support centers in D City. The instruments used were the life stress scale, social support scale, and K-EPDS. All the instruments were translated into their corresponding mother languages (Vietnamese, Cambodian, and Philippine) and notarized. Results: The item mean scores of life stress and social support were 2.65 and 3.17, respectively, on a 5-point Likert scale. The mean score of antepartum depression was 10.16, indicating that they were generally in a depressive state. A positive correlation was observed between life stress and antepartum depression (r=.59, p<.001). Social support was negatively correlated with life stress (r=-.42, p<.001) and antepartum depression (r=-.39, p<.001). The best predictors for antepartum depression were life stress, marital satisfaction, and emotional support, and they explained 43% of the variance. Conclusion: Antepartum depression in Southeast Asian immigrant brides was significantly associated with life stress as well as lack of emotional support. Emotional support may reduce their life stress and antepartum depression.