• 융합보안논문지
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• 제16권7호
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• pp.69-75
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• 2016

기술유출 방지를 위해 정부에서는 2007년도에 산업기술방지법을 제정하고 융합보안장비 구축을 권장하고 있다. 이에 기업에서 융합보안장비를 구축하는 원인을 파악하고자 하였다. 이를 위해 기존의 조사방식인 양적연구(quantitative research)와 달리 심층면담을 통해 원인을 찾아가는 질적연구(qualitative research) 중 바니 글래이저(Barney G. Glaser)와 안젤름 스트라우스(Anselm L. Strauss)가 사회과학의 질적방법론의 한 종류로 사용한 근거이론(grounded theory)을 사용하였다. 이에 정부로부터 융합보안장비 구축비를 지원받은 기업을 대상으로 조사한 결과 정부지원금이 높을수록, 대표자나 고객사의 요청이 있을 경우, 기술유출방지를 통해 업무효율성이 높을수록, 매출증대가 높을수록 융합보안장비를 구축하는 것으로 조사되었다.

• 산업기술연구
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• 제19권
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• pp.155-162
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• 1999

In the last few years the automatic classification of morpholgical landforms using GSIS and DEM was investigated. Particular emphasis has been put on the morphological point attribute approaches and the extraction of drainage basin variables from digital elevation models. The automated derivation of landforms has become a neccessity for quantitative analysis in geomorphology. Furthermore, the application of GSIS technologies has become an important tool for data management and numerical data analysis for purpose of geomorphological mapping. A process developed by Dikau et al, which automates Hanmond's manual process, was applied to the pyoung chang of the kangwon. Although it produced a classification that has good resemblance to the landforms in the area, it had some problems. For example, it produced a progressive zonation when landform changes from plains to mountains, it does not distinguish open valleys from a plains mountain interface, and it was affected by micro relief. Although automating existing quantitative manual processes is an important step in the evolution automation, definition may need to be calibrated since the attributes are oftem measured differently. A new process is presented that partly solves these problems.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3265-3270
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• 2012

Clinically, elevated cancer antigen 125 (CA-125) in blood predicts tumor burden in a woman's body, especially in the ovary, but cannot differentiate between malignant or benign. We here used intensive modern proteomic approaches to identify predictive proteins in the serum of women with elevated CA-125 to differentiate malignant from benign ovarian tumors. We identified differentially expressed proteins in serum samples of ovarian cancer (OC) patients, benign ovarian tumor (BT) patients, and healthy control women using mass spectrometry-based quantitative proteomics. Both the OC and BT patients had elevated CA-125. Quantitation was achieved using isobaric tags for relative and absolute quantitation. We obtained 124 quantified differential serum proteins in OC compared with BT. Two proteins, apolipoprotein A-4 (APOA4) and natural resistance-associated macrophage 1, were verified using Western blotting. Proteome profiling applied to OC cases identified several differential serum proteins in the serum of women with elevated CA-125. A novel protein, APOA4, has the potential to be a marker for malignant tumor differentiation in the serum of women with elevated CA-125.

• 유통과학연구
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• 제14권12호
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• pp.23-30
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• 2016

Purpose - As socially responsible consumption increases, green marketing emerges as a new philosophy in marketing. A number of companies are now putting forth green marketing strategies. But there is no single definition of "green brand" that can be used interchangeably. In this paper, we attempt to explore the meaning for "green brand," especially in Information and Technology products. Research design, data, and methodology - The author developed qualitative and quantitative research design. In particular, the paper approaches this topic from the Asian consumers' perspective and applies ethical concepts to green brand research. For this, Chinese and Korean consumers were used as consumer segmentation variables to investigate their ethical perspectives. Results - Qualitative research showed that there are several attributes and benefits we need to consider for green brand. Quantitative study showed positive correlations of the two variables: the higher the consumer ethics are, the more they prefer green brands. Conclusions - The current study shows that consumers clearly have a certain propensity toward green brand equity. Thus, marketers should consider the consumers' evaluation about green brands. This paper also proposes that ethics have a close relationship with green brand equity, and companies may use ethics in marketing strategy management.

• Toxicological Research
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• 제33권3호
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• pp.173-182
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• 2017

In silico methods to predict toxicity include the use of (Quantitative) Structure-Activity Relationships ((Q)SARs) as well as grouping (category formation) allowing for read-across. A challenging area for in silico modelling is the prediction of chronic toxicity and the No Observed (Adverse) Effect Level (NO(A)EL) in particular. A proposed solution to the prediction of chronic toxicity is to consider organ level effects, as opposed to modelling the NO(A)EL itself. This review has focussed on the use of structural alerts to identify potential liver toxicants. In silico profilers, or groups of structural alerts, have been developed based on mechanisms of action and informed by current knowledge of Adverse Outcome Pathways. These profilers are robust and can be coded computationally to allow for prediction. However, they do not cover all mechanisms or modes of liver toxicity and recommendations for the improvement of these approaches are given.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권2호
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• pp.959-981
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• 2017

Existing Android malware detection approaches mostly have concentrated on superficial features such as requested or used permissions, which can't reflect the essential differences between benign apps and malware. In this paper, we propose a quantitative calculation model of application risks based on the key observation that the essential differences between benign apps and malware actually lie in the way how permissions are used, or rather the way how their corresponding permission methods are used. Specifically, we employ a fine-grained analysis on Android application risks. We firstly classify application risks into five specific categories and then introduce comprehensive risk, which is computed based on the former five, to describe the overall risk of an application. Given that users' risk preference and risk-bearing ability are naturally fuzzy, we design and implement a fuzzy logic system to calculate the comprehensive risk. On the basis of the quantitative calculation model, we propose a risk classification based approach for Android malware detection. The experiments show that our approach can achieve high accuracy with a low false positive rate using the RandomForest algorithm.

• 대한공간정보학회지
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• 제12권2호
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• pp.73-77
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• 2004

대도시의 도심 정체나 대중교통 장려책과 같은 요소로 인해 대중교통에 대한 관심과 이용도가 증가하고 있다. 그러나 노선의 설계나 배분에 관한 연구가 미흡하고 적절한 정량적인 방법론이 구축되어 있지 않기 때문에 설계, 운영에 어려움을 겪고 있다. 노선의 공급과잉이나 공급부족으로 인해 접근성이 지역간에 편중되어 나타나며, 도시 각 구역의 정류장은 다른 지역으로 이동하는 시간과 비용, 심적 부담에 있어 큰 편차를 보이고 있다. 한편, Space Syntax 이론은 도시공간이나 건축공간의 접근성을 공간의 기하학적인 연결구조에 기반하여 정량적으로 산출하는데 사용되는 이론이다. 본 연구는 Space Syntax 이론을 대중교통 문제에 효과적으로 적용하기 위해 알고리즘을 수정하였으며, GIS를 이용하여 간략한 가상의 네트워크를 구축한 후 이를 적용하는 과정을 예시하였다.

• Bulletin of the Korean Chemical Society
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• 제29권3호
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• pp.656-662
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• 2008

Antagonists of the d -opioid receptor are effective in overcoming resistance against analgesic drugs such as morphine. To identify novel antagonists of the d -opioid receptor that display high potency and low resistance, we performed 3D-QSAR analysis using chemical feature-based pharmacophore models. Chemical features for d -opioid receptor antagonists were generated using quantitative (Catalyst/HypoGen) and qualitative (Catalyst/HipHop) approaches. For HypoGen analysis, we collected 16 peptide and 16 non-peptide antagonists as the training set. The best-fit pharmacophore hypotheses of the two antagonist models comprised identical features, including a hydrophobic aromatic (HAR), a hydrophobic (HY), and a positive ionizable (PI) function. The training set of the HipHop model was constructed with three launched opioid drugs. The best hypothesis from HipHop included four features: an HAR, an HY, a hydrogen bond donor (HBD), and a PI function. Based on these results, we confirm that HY, HAR and PI features are essential for effective antagonism of the d -opioid receptor, and determine the appropriate pharmacophore to design such antagonists.

• 산업경영시스템학회지
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• 제17권30호
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• pp.11-24
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• 1994

The problem of location for industries and residential quarters has undoubtedly been one of the most important factors to enhance human activities and standard of living. Nonetheless. there seem to be no such theories or approaches as to cope with this problem satisfactorily. As a matter of fact the evaluation of proposed locations so far has stuck to quantitative factors and thus the results are often rejected by the public or individuals. In deciding the location of industrial complex and/or residential quarters, the qualitative factors often play more important role than the quantitative factors. Moreover, it is quite possible for a proposed location to be disapproved for reasons other than quantifiable factors. This work presents an approach to multi-stage decision process of optimum location, particularly for residential quarters. The proposed approach consists of four stages. At the first stage, candidates for the location are searched and checked against musts. After this screening process, the candidates fulfilling the musts are evaluated both quantitatively and qualitatively at the second stage. The third stage is devoted to the integrated evaluation using diffrent weights for the two factors. At the final stage, a location is selected among the candidates evaluated at the earlier stages. This approach has been applied to and tested on a apartment-building project in Ulsan area. Difficulties arising from quantifying factors were encountered as expected. Sometimes decisions could be a matter of taste of the individuals concerned.

• 한국지하수토양환경학회지:지하수토양환경
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• 제26권6호
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• pp.95-105
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• 2021

Extensive groundwater abstraction has been recognized as one of the major challenges in management of coastal groundwater. The purpose of this study was to assess potential changes of groundwater distribution of northeastern Jeju Island over 10-year duration, where brackish water have been actively developed. To quantitatively estimate the coastal groundwater resources, numerical simulations using three-dimensional finite-difference density-dependent flow models were performed to describe spatial distribution of the groundwater in the aquifer under various pumping and recharge scenarios. The simulation results showed different spatial distribution of freshwater, brackish, and saline groundwater at varying seawater concentration from 10 to 90%. Volumetric analysis was also performed using three-dimensional concentration distribution of groundwater to calculate the volume of fresh, brackish, and saline groundwater below sea level. Based on the volumetric analysis, a quantitative analysis of future seawater intrusion vulnerability was performed using the volume-based vulnerability index adopted from the existing analytical approaches. The result showed that decrease in recharge can exacerbate vulnerability of coastal groundwater resources by inducing broader saline area as well as increasing brackish water volume of unconfined aquifers.