• 한국전산유체공학회:학술대회논문집
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• 2005.04a
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• pp.1-13
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• 2005

Fluid flows within microchannels are characterized by low Reynolds numbers. Therefore the effect of mixing is a crucial factor in design of the channels. Since the action of the electro-osmotic or magnetic forces used in the mixing enhancement is usually periodic in the three-dimensional channel configuration, use of the various concepts of chaotic advection is reasonable in the quantification of the stirring effect. In this paper, the details of the method of material-stretching mapping is explained. The actual application of the method to the screw extruder is also presented.

• YAKHAK HOEJI
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• v.60 no.1
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• pp.15-20
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• 2016

Globotriaosylsphingosine (lyso Gb3) is considered as one of the biomarkers for Fabry disease. A rapid and simple UPLC-MS/MS method was developed for the determination of reliable biomarker, lyso Gb3. Total analytical procedure takes only 15 min including sample preparation and MS/MS analysis. Limit of detection was 0.85 ng/ml (S/N=3). The calibration curve was linear over the range of 2.0~400.0 ng/ml ($R^2=0.9999$). Inter-day and intra-day assay accuracy were 93.4~100.6% (RSD, 0.6~6.0%) and 97.5~100.7% (RSD, 3.6~5.2%). Absolute recoveries of 97.6~98.6 showed excellence of a new analytical method. The method was applied to human and mice urines, proved the suitability for the quantification of lyso-Gb3 for screening, diagnosis and therapeutic monitoring of Fabry disease patients.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.54 no.11
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• pp.533-539
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• 2005

According to NERC definition, Available Transfer Capability (ATC) is a measure of the transfer capability remaining in the physical transmission network for the future commercial activity. To calculate Available Transfer Capability, accurate and defensible Total Transfer Capability, Capacity Benefit Margin and Transmission Reliability Margin should be calculated in advance. This paper proposes a method to quantify time varying Available Transfer Capability based on probabilistic approach. The uncertainties of power system and market are considered as complex random variables. Total Transfer Capability is determined by optimization technique such as SQP(Sequential Quadratic Programming). Transmission Reliability Margin with the desired probabilistic margin is calculated based on Probabilistic Load Flow analysis, and Capacity Benefit Margin is evaluated using LOLE of the system. Suggested Available Transfer Capability quantification method is verified using IEEE RTS with 72 bus. The proposed method shows efficiency and flexibility for the quantification of Available Transfer Capability.

• Smart Structures and Systems
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• v.25 no.1
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• pp.47-56
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• 2020

This paper proposes a model-based approach for structural damage identification and quantification. Using pseudo modal strain energy and mode shape vectors, a damage-sensitive objective function is introduced which is suitable for damage estimation and quantification in shear frames. Whale optimization algorithm (WOA) is used to solve the problem and report the optimal solution as damage detection results. To illustrate the capability of the proposed method, a numerical example of a shear frame under different damage patterns is studied in both ideal and noisy cases. Furthermore, the performance of the WOA is compared with particle swarm optimization algorithm, as one the widely-used optimization techniques. The applicability of the method is also experimentally investigated by studying a six-story shear frame tested on a shake table. Based on the obtained results, the proposed method is able to assess the health of the shear building structures with high level of accuracy.

• Mass Spectrometry Letters
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• v.15 no.2
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• pp.107-119
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• 2024

We aimed to develop a suitable quantification method for detecting asparagine deamidation and aspartic acid isomerization in peptide mapping using LC-MS. Our assessment of its validity and suitability involved comparing its quantitative findings with those obtained from cation-exchange chromatography and capillary electrophoresis methods. By subjecting trastuzumab to rigorous conditions to induce these modifications, we validated the efficacy of this new analytical method in peptide mapping via LC-MS, evaluating both qualitative and quantitative aspects of asparagine deamidation and aspartic acid isomerization. Our investigation underscored the significance of enzyme selection and the presence of miss-cleaved or non-specific peptides in achieving accurate quantitative results. The experimental results demonstrated a strong correlation with results from cation-exchange chromatography and capillary electrophoresis analyses, confirming the reliability of the LC-MS based peptide mapping approach.

• The KIPS Transactions:PartA
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• v.15A no.6
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• pp.351-360
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• 2008

It seems reasonable to assume that the individualized learning means more than simple teaching-learning method, so the instructional method has attracted a fair amount of attention not only in classroom, but also in the field of a adult education, cooperate education, and so on. In order to have an effect on individualized learning, we need to analyze and measure the learner's characteristic. However it is difficult to represent in quantified form because the conception and category of learner's characteristic is various and extensive. Therefore, in this paper, we propose a quantification method of learner's characteristic, which is limited to learner's cognitive structure and style, and is represented in the light of connectionism, verify the validity. The learner's cognitive structure in this paper was represented, which simplified the learner's cognitive structure. Additionally, the cognitive style in this paper was limited to inertia of knowledge for learner's cognition.

• Applied Chemistry for Engineering
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• v.34 no.4
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• pp.450-454
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• 2023

Chloride ions in the alloy powder used as flux in Flux Cored Arc Welding (FCAW) can cause pores on the bead surface of the welding metal to cause defects, or chloride remaining in the alloy powder can cause corrosion of the metal. Combustion-ion chromatography is mainly used to quantify the chloride ions in alloy powder, but there is a limitation in that the equipment is expensive and requires a high degree of expertise. Therefore, this study aims to find an easy and accurate quantification method in the field by comparing combustion-ion chromatography (C-IC), which is mainly used for chloride ion quantification of alloy powder, X-ray fluorescence analysis (XRF), and potentiometric titration. In this article, magnesium-aluminum alloy powder is applied to the quantification of chloride ions because it is most commonly used as flux. This study confirmed that potentiometric titration can be applied to the quantification of chloride ions in the alloy powder in the industry field.

• Nuclear Engineering and Technology
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• v.55 no.1
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• pp.119-130
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• 2023

Among the various elements of probabilistic safety assessment (PSA), human failure events (HFEs) and their dependencies are major contributors to the quantification of risk of a nuclear power plant. Currently, the dependency among HFEs is reflected using a post-processing method in PSA, wherein several drawbacks, such as limited propagation of minimal cutsets through the fault tree and improper truncation of minimal cutsets exist. In this paper, we propose a method to model the HFE dependency directly in a fault tree using the if-then-else logic. The proposed method proved to be equivalent to the conventional post-processing method while addressing the drawbacks of the latter. We also developed a software tool to facilitate the implementation of the proposed method considering the need for modeling the dependency between multiple HFEs. We applied the proposed method to a specific case to demonstrate the drawbacks of the conventional post-processing method and the advantages of the proposed method. When applied appropriately under specific conditions, the direct fault-tree modeling of HFE dependency enhances the accuracy of the risk quantification and facilitates the analysis of minimal cutsets.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.35 no.4
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• pp.231-240
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• 2017

This paper aims to study a method to estimate precise carbon absorption by quantification of forest information that uses accurate LiDAR data, hyperspectral image. To estimate precise carbon absorption value by using spatial data, a problem was found out of carbon absorption value estimation method with statistical method, which is already existed method, and then offered optimized carbon absorption estimation method with spatial information by analyzing with methods of compare digital aerial photogrammetry and LiDAR data. It turned out possible Precise classification and quantification in case of using LiDAR and hyperspectral image. Various classification of tree species was possible with use of LiDAR and hyperspectral image. Classification of hyperspectral image was matched in general with field survey and Mahalanobis distance classification method. Precise forest resources could be extracted using high density LiDAR data. Compared with existing method, 19.7% in forest area, 19.2% in total carbon absorption, 0.9% in absorption per unit area of difference created, and improvement was found out to be estimated precisely in international code.

• Korean Journal of Pharmacognosy
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• v.41 no.4
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• pp.323-327
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• 2010

A high performance liquid chromatographic (HPLC) method for the simultaneous determination of dictamine, obacunone and fraxinellone was established for the quality control of traditional herb Dictamnus dasycarpus cortex. Separation and quantification were successfully achieved with a Shiseido C18 column ($5\;{\mu}m$, 4.6 mm I.D. ${\times}$ 250 mm) by gradient elution of a mixture of methanol and water at a flow rate of 1.0 ml/min. The diode-array UV/Vis detector (DAD) was used for the detection and the wavelength for quantification was set at 236 nm. The presence of dictamine, obacunone and fraxinellone in this extract was ascertained by retention time, spiking with each authentic standard and UV spectrum. All three compounds showed good linearity ($r^2$ > 0.999) in relatively wide concentration ranges. The R.S.D. recovery of each compound was 101.0~103.7% with R.S.D. values less than 1.0%. This method was successfully applied to the determination of contents of dictamine, obacunone and fraxitnellone in three commercial products of D. dasycarpus cortex. These results suggest that the developed HPLC method is simple, effective and could be readily utilized as a quality control method for commercial products.