• International Journal of Stem Cells
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• 제17권2호
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• pp.120-129
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• 2024

Recent amendments to regulatory frameworks have placed a greater emphasis on the utilization of in vitro testing platforms for preclinical drug evaluations and toxicity assessments. This requires advanced tissue models capable of accurately replicating liver functions for drug efficacy and toxicity predictions. Liver organoids, derived from human cell sources, offer promise as a reliable platform for drug evaluation. However, there is a lack of standardized quality evaluation methods, which hinders their regulatory acceptance. This paper proposes comprehensive quality standards tailored for liver organoids, addressing cell source validation, organoid generation, and functional assessment. These guidelines aim to enhance reproducibility and accuracy in toxicity testing, thereby accelerating the adoption of organoids as a reliable alternative or complementary tool to animal testing in drug development. The quality standards include criteria for size, cellular composition, gene expression, and functional assays, thus ensuring a robust hepatotoxicity testing platform.

• Safety and Health at Work
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• 제5권2호
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• pp.80-85
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• 2014

Background: Currently available questionnaires for evaluating the quality of worklife do not fully examine every factor related to worklife in all cultures. A tool in Thai is therefore needed for the direct evaluation of the quality of worklife. Our aim was to translate the Work-related Quality of Life Scale-2 (WRQLS-2) into Thai, to assess the validity and reliability of the Thai-translated version, and to examine the tool's accuracy vis-$\grave{a}$-vis nursing in Thailand. Methods: This was a descriptive correlation study. Forward and backward translations were performed to develop a Thai version of the WRQLS. Six nursing experts participated in assessing content validity and 374 registered nurses (RNs) participated in its testing. After a 2-week interval, 67 RNs were retested. Structural validity was examined using principal components analysis. The Cronbach's alpha values were calculated. The respective independent sample t test and intraclass correlation coefficient were used to analyze known-group validity and test-retest reliability. Multistate sampling was used to select 374 RNs from the In- and Outpatient Department of Srinagarind Hospital of the Khon Kaen University (Khon Kaen, Thailand). Results: The content validity index of the scale was 0.97. Principal components analysis resulted in a seven-factor model, which explains 59% of the total variance. The overall Cronbach's alpha value was 0.925, whereas the subscales ranged between 0.67 and 0.82. In the assessment results, the known-group validity was established for the difference between civil servants and university employees [F (7.982, 0.005) and t (3.351; p < 0.05)]. Civil servants apparently had a better quality worklife, compared to university employees. Good test-retest reliability was observed (r = 0.892, p < 0.05). Conclusion: The Thai version of a WRQLS appears to be well validated and practicable for determining the quality of the work-life among nurses in Thailand.

• 가정과삶의질연구
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• 제22권4호
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• pp.15-27
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• 2004

This study investigated the factors in evaluating internet shopping mall sites, and developed a self-report evaluation scale of such sites, This article identifies factors to determine criteria for evaluating the sites from the consumers' viewpoint. Eighty three items were extracted initially, which were then categorized as follows: \circled1 Type of business, \circled2 Navigation ease, \circled3 Technological level, \circled4 Design of sites, \circled5 Communication ease, \circled6 Information available, \circled7 Ease of access, and \circled8 Site security, Overall reliability coefficients were high in the individual domains ($\alpha$=.86 to $\alpha$=.95). Face validity and contents validity were demonstrated to be good, There were significant differences in the means of these categories. The results also show that the technological level is the most important in shopping mall sites evaluation. These results may be used not only as a tool to evaluate shopping mall sites but also as a guideline to improve the quality of a shopping mall site that is under development.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2002년도 추계학술대회 논문집
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• pp.446-449
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• 2002

Recently, advanced manufacturing system with high speed and intelligent have been developed for the betterment of machining ability. In this case, reliability prediction work with motion characteristic evaluation of sliding cover has also important roll from design procedure to manufacturing and assembly process. Accordingly in this study, H/W test -bed system for reliability evaluation of sliding cover has been developed to obtain proper reference data for design of new model, and also prevention trouble, quality and life cycle improvement extremely for advanced mother machinary.

• 한국신뢰성학회지:신뢰성응용연구
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• 제3권1호
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• pp.41-58
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• 2003

Recently, the reliability evaluation and analysis are applied for many industrial products, and many products are required to guarantee in quality and in efficiency. The purpose of this paper is to present some of reliability prediction methodologies that are applicable to machine tools. Especially ATC (Automatic Tool Changer) and Interface Card of PC-NC, which are core components of the machine tools, were chosen as the target of the reliability evaluation and analysis. The results of this research has shown the failure rate, MTBF(Mean Time Between Failure), and reliability for those components. It is expected that proposed methodologies will be applicable to evaluation of reliability for other industrial products.

• 대한방사선기술학회지:방사선기술과학
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• 제27권2호
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• pp.7-12
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• 2004

MDCT는 비침습적인 방법으로 관상동맥 질환을 검사하는데 유용하다고 알려져 있다. 하지만 영상의 질에 있어서 환자의 심장박동이 결정적인 영향을 주게 된다. 특히 심장박동이 불규칙하거나 조기 심실수축 환자일 경우 영상을 재구성하는데 있어 왜곡 현상이 증가하여 진단에 어려움을 초래한다. 최근 본원에서 심장박동이 불규칙한 환자에서 영상 재구성시 불규칙한 R-R 간격을 조정한 후 얻은 영상이 artifact가 감소하는 현상을 경험한 바 있다. 따라서 본 연구에서는 다양한 교정 방법(disable, inesrt, R-R interval 교정)이 영상의 질에 어떤 영향이 있는지를 알아보고자 한다. 심박동이 불규칙한 24명의 환자에서 교정방법에 따라 영상을 재구성한 결과 R-R Interval 조정에서 통계학적으로 유의한 결과를 얻을 수 있었다(p<0.05). 본 연구에서는 R-R Interval 조정에서 가장 우수한 영상을 얻을 수 있었으며, 향후 심장 질환의 진단에 도움을 줄 수 있는 기초연구로서 그 가치가 충분하리라 사료된다.

• 문화기술의 융합
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• 제8권6호
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• pp.471-478
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• 2022

좋은 수업은 수업을 구성하는 요소들이 하나의 체제로서 유기적 연관성을 갖는다. 평가 준거에 대한 충분한 설명이나 합의 없는 일방적 평가, 평가과정의 신뢰성을 담보할 수 없는 주관적 평가 그리고 학습 과정과 분리된 탈 맥락화된 평가는 좋은 수업이나 건강한 학습생태계를 위협하는 요소가 될 수 있다. 이 연구는 교육 평가와 관련된 문제를 해결하기 위해 루브릭(rubric)을 통한 평가와 그 효과를 분석하였다. '루브릭'은 수업목표를 토대로 수행과제를 평가하는 준거와 수행의 질을 여러 단계로 상세히 묘사한 서술적 평가도구다. 영화 리터러시 평가를 위해 적용한 루브릭은 '분석적 루브릭'으로서 영화 이해 리터러시, 영화 제작 리터러시, 그리고 영화 활용 리터러시를 포괄한다. 루브릭에 대해 학습자들은 타당하고 매우 유용한 학습 성찰 도구로 인식하였다.

• Nuclear Engineering and Technology
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• 제35권6호
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• pp.556-565
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• 2003

A quality assurance safety assessment database, called QUARK (QUality Assurance Program for Radioactive Waste Management in Korea), has been developed to manage both analysis information and parameter database for safety assessment of low- and intermediate-level radioactive waste (LILW) disposal facility in Korea. QUARK is such a tool that serves QA purposes for managing safety assessment information properly and securely. In QUARK, the information is organized and linked to maximize the integrity of information and traceability. QUARK provides guidance to conduct safety assessment analysis, from scenario generation to result analysis, and provides a window to inspect and trace previous safety assessment analysis and parameter values. QUARK also provides default database for safety assessment staff who construct input data files using SAGE(Safety Assessment Groundwater Evaluation), a safety assessment computer code.

• 한국항공우주학회지
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• 제41권1호
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• pp.61-69
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• 2013

항공기 비행성 평가 과정에서는 수많은 평가의 반복이 필요하기 때문에 평가 시스템에 있어서 간결하고 명확한 응용 인터페이스가 중요하다. 본 비행성 평가 프로그램은 달라진 트림 조건의 사용자 환경과 함께 효율적인 비행성 평가 사용자 환경을 구현하였다. 그리고 14 항목으로 선별된 무인 고정익기의 비행성 평가 자동화 모듈을 모두 탑재한 종합평가 환경을 구성하였다. 이에 따라 비행제어시스템 개발은 물론 비행성이 고려된 항공기를 개발함에 있어서 검증 및 평가 과정에 소요되는 비용과 시간을 대폭 감소시키고 향후 확장성을 겸비한 유용한 시험 평가 검증 도구로 활용될 수 있을 것으로 사료된다.

• 간호행정학회지
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• 제9권1호
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• pp.89-101
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• 2003

Purpose : this study was to examine the effect of using a nursing standards for the quality of nursing care in musculo-skeletal patients. Method : The approach to nursing quality assurance evaluation was selected process-outcome framework. The subjects ware 100 case of musculo-skeletal patients in orthopedic surgery nursing care unit of E. university hospital in seoul. The data of a control group were collected from 23 December 2001 to 20 March 2002 and an experimental group were collected from 1 June to 25 August 2002. The instruments used for this study were a nursing care standards in musculo-skeletal disorder patients developed by the investigator and an evaluation tool for the quality of nursing care in orthopedic surgery patients developed by soon-ook Choi in 1995. It's reliability is Cronbach alpha=.8628. The data were analyzed by means of $x^1$-test, t-test, ANOVA with SPSS program. Results : This study are as fellows : 1. Scores of the quality of nursing care in standard 1 in the experimental group were higher than those of the control group with no significant difference(t=-8.793, p=.000), scores of the quality of nursing care in standard 2 in the experimental group were higher than those of the control group with significant difference(t=-8.793, p=.000) and standard 3 in the experimental group were higher than those of the control group with significant difference(t=-10.550, p=.000). scores of the quality of nursing care in standard 4 in the experimental group were higher than those of the control group with significant difference(t=-8.793, p=.000). scores of the quality of nursing care in standard 4 in the experimental group were higher than those of the control group with no significant difference(t=-1.833, p=.070). 2. Scores of the quality of nursing care in criteria 28 of 33 criteria in the experimental group were higher than those of the control group with significant difference in 12 criteria(p<.05 ). 3. Scores of the quality of nursing care in standard 1 to standard 4(process evaluation); the experimental group were higher than those of the control group with significant difference(t=-10.704, p=.000). scores of the quality of nursing care in standard 5(outcome evaluation); the experimental group were higher than those of the control group. but no significant difference(t=-1.833, p=.070). 4. Scores of the quality of nursing care in experimental group were higher than those of the control group with significant difference(t=-10.794, p=.000). Conclusion : Through this study, I'm sure that using a nursing care standards in musculo-skeletal disorder patients improve quality of nursing care and nursing care standards are effective nursing care.