• Title/Summary/Keyword: Quality Control Center

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Quality Improvement through Monitoring of Imported Medicinal Herbs (수입한약재 품목 분석을 통한 품질 제고)

  • Choi, Go-Ya;Ko, Byoung-Seob;Jang, Seol;Chae, Sung-Uk;Lee, Hye-Won;Lee, Mi-Young
    • The Korea Journal of Herbology
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    • v.24 no.4
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    • pp.63-67
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    • 2009
  • Objectives : Quality control for imported medicinal herbs is duty for regulation, however to the best of our knowledge there has been no report regarding quality control of imported ones. Therefore, this study investigated the data of imported ones for monitoring quality issue. Methods : These data are categorized according to item, the amount of import, country, inspection item, suitability, and incongruity reason based on the 248 results performed by KIOM. Results : China is the number one country for import with the value of 73%. Inspected medicinal herbs were 139 species, among them Poria is ranked as top for requested number and the amount of import. The amount of import is similar between high ranking 20 species and low ranking 119 ones, showing high ranking ones are major. The incongruity ratio was 7.7% from the total number of inspected items, the reason for incongruity was excess of tolerable amount of Cd residue. Conclusions : From the data, it is effective way to focus on high ranking herbs for evaluating imported herbs for quality control. The study of mechanism on Cd accumulation and its decrease is essential for environmental matter. And identification and storage for mixed used and easily decomposable herbs are remained for further study. Our study might be small step for showing guideline for proper quality control.

Analysis of Quality Control Technique Characteristics on Single Polarization Radar Data (단일편파 레이더자료 품질관리기술 특성 분석)

  • Park, Sora;Kim, Heon-Ae;Cha, Joo Wan;Park, Jong-Seo;Han, Hye-Young
    • Atmosphere
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    • v.24 no.1
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    • pp.77-87
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    • 2014
  • The radar reflectivity is significantly affected by ground clutter, beam blockage, anomalous propagation (AP), birds, insects, chaff, etc. The quality of radar reflectivity is very important in quantitative precipitation estimation. Therefore, Weather Radar Center (WRC) of Korea Meteorological Administration (KMA) employed two quality control algorithms: 1) Open Radar Product Generator (ORPG) and 2) fuzzy quality control algorithm to improve quality of radar reflectivity. In this study, an occurrence of AP echoes and the performance of both quality control algorithms are investigated. Consequently, AP echoes frequently occur during the spring and fall seasons. Moreover, while the ORPG QC algorithm has the merit of removing non-precipitation echoes, such as AP echoes, it also removes weak rain echoes and snow echoes. In contrast, the fuzzy QC algorithm has the advantage of preserving snow echoes and weak rain echoes, but it eliminates the partial area of the contaminated echo, including the AP echoes.

Statistical Analysis of Quality Control Data of Blood Components (혈액성분제제 품질관리 자료의 통계학적인 비교)

  • Kim, Chongahm;Seo, Dong Hee;Kwon, So Yong;Oh, Yuong Chul;Lim, Chae Seung;Jang, Choong Hoon;Kim, Soonduck
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.1
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    • pp.19-26
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    • 2004
  • According to increase of domestic blood components use, the quality control of blood components is necessary to support good products. The purpose of this study is used to provide the producing index of the good product as compared with the accuracy and validity for the distribution of the quality control data. The value of mean, standard deviation, 95% confidence interval and degree of normal distribution of data were calculated by univariate procedure, the value of monthly mean of each blood centers per items were compared by Analysis of Variance(ANOVA) test for the degree of distribution. When there was difference among the mean values, the Duncan's multiple range test was done to confirm the difference. Finally, methods for accessing accuracy and validity of the quality data was done by the Contingency table test. The quality data of five blood centers was showed to the normal distribution and it was in a acceptable range. For each blood centers, the monthly means of Hematocrit(Hct), Platelet(PLT) and pH were not significantly different except Hct of C center, PLT of B, D center and pH of A center. The quality data per items was graded according to quality to six level. As a result of the comparative analysis, the monthly means of Hct of C and E center was significantly different higher than that of D, B and A center. The monthly means of PLT of A center and pH of C center was significantly different higher than that of the others. In the accuracy and validity of the quality control data, C center for Hct, A center for PLT and C center for pH were better than the other. The C blood center was most satisfiable and stable in the quality control for blood component. If the quality control method used in C blood center is adopted in other blood centers, the prepared level of the blood component of the center will be improved partly.

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Effect of fermented blueberry on the oxidative stability and volatile molecule profiles of emulsion-type sausage during refrigerated storage

  • Zhou, Hengyue;Zhuang, Xinbo;Zhou, Changyu;Ding, Daming;Li, Chunbao;Bai, Yun;Zhou, Guanghong
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.5
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    • pp.812-824
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    • 2020
  • Objective: The aim of this work was to assess the effect of fermented blueberry (FB; 2%, 4%, and 6%) on the oxidative stability and volatile molecule profiles of emulsion-type sausage stored at 4℃ for 28 days. Methods: The antioxidant activity of FB was determined through radical-scavenging activity against 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radicals. Four formulations of sausage treatments with different FB levels (0%, 2%, 4%, 6%) were prepared, then peroxide value (POVs), thiobarbituric acid-reactive substances (TBARS) values, protein carbonyls and thiol groups were measured. The aroma profiles of sausages for each treatment was also determined. Results: The half maximal inhibitory concentration indicated that FB had greater scavenging ability than ascorbic acid against DPPH and hydroxyl radicals. Sausages with FB significantly retarded increases in POVs and TBARS, as well as in the content of protein carbonyls during all storage days (p<0.05). Particularly, 4% and 6% FB-treated sausages had better oxidation inhibition effects. However, FB accelerated the reduction in thiol groups (p<0.05). Additionally, FB inhibits the excessive formation of aldehyde compounds; for example, hexanal, which may cause rancid flavors, decreased from 58.25% to 19.41%. FB also created 6 alcohols (i.e., 2-methyl-1-propanol, 3-methyl-1-butanol, and phenylethyl alcohol), 5 ester compounds (i.e., ethyl acetate, ethyl lactate, and ethyl hexanoate) and 3-hydroxy-2-butanone in the sausages that contribute to sausage flavors. The principal component analysis showed that the aroma profiles of sausages with and without FB are easily identified. Conclusion: The addition of FB could significantly reduce the lipid and protein oxidation and improve oxidative stability for storage. Also, adding FB could inhibit rancid flavors and contribute to sausage flavors.

Operational Hydrological Forecast for the Nakdong River Basin Using HSPF Watershed Model (HSPF 유역모델을 이용한 낙동강유역 실시간 수문 유출 예측)

  • Shin, Changmin;Na, Eunye;Lee, Eunjeong;Kim, Dukgil;Min, Joong-Hyuk
    • Journal of Korean Society on Water Environment
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    • v.29 no.2
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    • pp.212-222
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    • 2013
  • A watershed model was constructed using Hydrological Simulation Program Fortran to quantitatively predict the stream flows at major tributaries of Nakdong River basin, Korea. The entire basin was divided into 32 segments to effectively account for spatial variations in meteorological data and land segment parameter values of each tributary. The model was calibrated at ten tributaries including main stream of the river for a three-year period (2008 to 2010). The deviation values (Dv) of runoff volumes for operational stream flow forecasting for a six month period (2012.1.2 to 2012.6.29) at the ten tributaries ranged from -38.1 to 23.6%, which is on average 7.8% higher than those of runoff volumes for model calibration (-12.5 to 8.2%). The increased prediction errors were mainly from the uncertainties of numerical weather prediction modeling; nevertheless the stream flow forecasting results presented in this study were in a good agreement with the measured data.

Effects of alanyl-glutamine supplementation on the small intestinal mucosa barrier in weaned piglets

  • Xing, Shen;Zhang, Bolin;Lin, Meng;Zhou, Ping;Li, Jiaolong;Zhang, Lin;Gao, Feng;Zhou, Guanghong
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.2
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    • pp.236-245
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    • 2017
  • Objective: The study was to investigate the effects of alanyl-glutamine (Ala-Gln) and glutamine (Gln) supplementation on the intestinal mucosa barrier in piglets. Methods: A total of 180 barrows with initial weight $10.01{\pm}0.03kg$ were randomly allocated to three treatments, and each treatment consisted of three pens and twenty pigs per pen. The piglets of three groups were fed with control diet [0.62% alanine (Ala)], Ala-Gln diet (0.5% Ala-Gln), Gln diet (0.34% Gln and 0.21% Ala), respectively. Results: The results showed that in comparison with control diet, dietary Ala-Gln supplementation increased the height of villi in duodenum and jejunum (p<0.05), Gln supplementation increased the villi height of jejunum (p<0.05), Ala-Gln supplementation up-regulated the mRNA expressions of epidermal growth factor receptor and insulin-like growth factor 1 receptor in jejunal mucosa (p<0.05), raised the mRNA expressions of Claudin-1, Occludin, zonula occludens protein-1 (ZO-1) and the protein levels of Occludin, ZO-1 in jejunal mucosa (p<0.05), Ala-Gln supplementation enlarged the number of goblet cells in duodenal and ileal epithelium (p<0.05), Gln increased the number of goblet cells in duodenal epithelium (p<0.05) and Ala-Gln supplementation improved the concentrations of secretory immunoglobulin A and immunoglobulin G in the jejunal mucosa (p<0.05). Conclusion: These results demonstrated that dietary Ala-Gln supplementation could maintain the integrity of small intestine and promote the functions of intestinal mucosa barriers in piglets.

Quality Assessment of Curcuma longa L. by Gas Chromatography-Mass Spectrometry Fingerprint, Principle Components Analysis and Hierarchical Clustering Analysis

  • Li, Ming;Zhou, Xin;Zhao, Yang;Wang, Dao-Ping;Hu, Xiao-Na
    • Bulletin of the Korean Chemical Society
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    • v.30 no.10
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    • pp.2287-2293
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    • 2009
  • Gas Chromatography-Mass Spectrometry (GC-MS) fingerprint analysis, Principle Components Analysis (PCA), and Hierarchical Cluster Analysis (HCA) were introduced for quality assessment of Curcuma longa L. (C. longa). The GC-MS fingerprint method was developed and validated by analyzing 33 batches of samples of C. longa from different geographic locations. 18 chromatographic peaks were selected as characteristic peaks and their relative peak areas (RPA) were calculated for quantitative expression. Two principal components (PCs) were extracted by PCA. C. longa collected from Guizhou and Fujian were separated from other samples by PC1, capturing 71.83% of variance. While, PC2 contributed for their further separation, capturing 11.13% of variance. HCA confirmed the result of PCA analysis. Therefore, GC-MS fingerprint study with chemometric techniques provides a very flexible and reliable method for quality assessment of C. longa.

The Effect of Operational Control Center's Service Quality on Airline Staff's Job Engagement (종합통제센터의 서비스품질이 항공사 직원의 직무몰입에 미치는 영향)

  • Kim, Hyo Joong
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.28 no.1
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    • pp.14-21
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    • 2020
  • Here I investigate what effects Operational Control Center(OCC)'s service quality may have on airline staff's job engagement. My analysis reveals that airline OCC's service quality has a meaningful effect on airline staff's service satisfaction, and that service satisfaction mediates a meaningful effect on staff's job engagement. It was suggested that improving OCC's service quality leads to higher staff's job engagement. Accordingly, I suggest methods of improving OCC's service quality. I find that the importance of contributing factors on OCC's service quality are as follows, in order of most to least important: professionalism, assurance, empathy, reliability, organizational culture, and responsiveness. The results of this study are relevant not only for airlines but also for government agencies such as the National Emergency Management Agency, the Korea Forest Service, the National Police Agency and the Korea Coast Guard that operate aircraft and must ensure aviation safety.

Oxidative stress impairs the meat quality of broiler by damaging mitochondrial function, affecting calcium metabolism and leading to ferroptosis

  • Chen, Zuodong;Xing, Tong;Li, Jiaolong;Zhang, Lin;Jiang, Yun;Gao, Feng
    • Animal Bioscience
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    • v.35 no.10
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    • pp.1616-1627
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    • 2022
  • Objective: This work was conducted to investigate the effects of oxidative stress on meat quality, mitochondrial function, calcium metabolism and ferroptosis of broilers. Methods: In this study, a total of 144 one-day-old male Ross 308 chicks were divided into 3 groups (control group, saline group, and hydrogen peroxide [H2O2] group) with 6 replicates of 8 broilers each. The study lasted for 42 d. The broilers in the saline and H2O2 groups were intraperitoneally injected with 0.75% saline and 10.0% H2O2 on the 16th and 37th day of the experimental period respectively, the injection volumes were 1.0 mL/kg of broiler body weight. On the 42nd day of the experimental period, two chicks were randomly selected from each cage, a total of thirty-six chicks were stunned by electric shock and slaughtered to collect breast muscle samples. Results: The H2O2 exposure reduced pH value, increased drip loss and shear force of breast meat (p<0.05), impaired the ultrastructure and function of mitochondria. The H2O2 exposure damaged the antioxidant system in mitochondria, excessive reactive oxygen species carbonylation modified calcium channels on mitochondria, which impaired the activities of key enzymes on calcium channel, resulted in the increased calcium concentration in cytoplasm and mitochondria (p<0.05). In addition, the H2O2 exposure increased the iron content and lipid peroxidation (p<0.05), which induced ferroptosis. Conclusion: Oxidative stress could impair meat quality by causing mitochondrial dysfunction, resulting in calcium metabolism disorder and ferroptosis.

Analysis of Pollutant Characteristics in Nakdong River using Confirmatory Factor Modeling (확인적 요인모형을 이용한 낙동강 유역의 오염특성 분석)

  • Kim, Mi-Ah;Kang, Taegu;Lee, Hyuk;Shin, Yuna;Kim, Kyunghyun
    • Journal of Korean Society on Water Environment
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    • v.28 no.1
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    • pp.84-93
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    • 2012
  • The study was conducted to analyze the spatio-temporal changes in water quality of the major 36 sampling stations of Nakdong River, depending on each station, season using the 17 water quality variables from 2000 to 2010. The result was verified to interpret the characteristics of water quality variables in a more accurate manners. According to the Principal component analysis (PCA) and Exploratory factor analysis (EFA) results; the results of these analyses were identified 4 factors, Factor 1 (nutrients) included the concentrations of T-N, T-P, $NO_{3}-N$, $PO_{4}-P$, DTN, DTP for sampling station and season, Factor 2 (organic pollutants) included the concentrations of BOD, COD, Chl-a, Factor 3 (microbes) included the concentrations of F.Coli, T.Coli, and Factor 4 (others) included the concentrations of pH, DO. The results of a Cluster analysis indicated that Geumhogang 6 was the most contaminated site, while tributaries and most of the down stream sites of Nakdong River were mainly affected by each nutrients (Factor 1) and organic pollutants (Factor 2). The verification consequence of Confirmatory factor analysis (CFA) from Exploratory factor analysis (EFA) result can be summarized as follows: we could find additional relations between variables besides the structure from EFA, which we obtained through the second-order final modeling adopted in CFA. Nutrients had the biggest impact on water pollution for each sampling station and season. In particular, It was analyzed that P-series pollutant should be controlled during spring and winter and N-series pollutant should be controlled during summer and fall.