• 한국지반공학회논문집
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• 제20권6호
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• pp.41-49
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• 2004

진동전달을 차단하는 공법으로는 방진구나 방진벽공법 등이 있으며 최근에는 다양한 재료를 사용한 차단벽공법 등이 제안되고 현장 시공도 다수 행해지고 있으며 또한 저감효과가 확인되고 있다. 그러나 이들 공법은 가진원의 특성, 지반조건, 차단벽의 매개변수 등이 복잡하여 합리적이고 정량적인 진동저감 평가방법이 아직 확립되어 있지 않다. 본 연구는 이러한 관점에서 지표면에 점가진이 전달될 경우 진동차단벽공법을 원심모형실험을 통하여 재현하고자 하였다. 이를 위해 차단벽재의 강성 및 차단벽재의 타설 심도를 변화시키는 실험을 실사하고 이들의 차이가 방진효과에 미치는 영향에 대하여 검토하였다. 본 연구결과 원심모형 실험장치를 환경진동 문제에 적용하고 파동의 지반내 전달현상 및 메카니즘을 파악하고 본 연구에서 개발한 충격 재하장치의 적용성을 확인했다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회A
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• pp.1367-1372
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• 2008

A plate type supporting structure of a tube bundle in axial flow generates a certain band of a high frequency periodic excitation of a vortex shedding and/or a flow separation due to sharp edge of the plate thickness and a severe pressure drop due to a cross-sectional area of the supports. With a design consideration of the low vibration and a small flow resistance, the analysis method is uniquely confined to an experimental approach because a complex geometry of a cylindrical tube bundle and/or physical phenomena related to the fluid-structure interaction of tube bundle in a flow impede a theoretical or a numerical approach. A 5x5 cylindrical tube bundle with 5 supports which were discretely located along the bundle's axis was tested in the FIVPET hydraulic test loop for a design evaluation and an analysis perspectives. A high frequency flow-induced vibration of the supporting structures of the cylindrical tube bundle was measured at a outer surface of a supporting structure through a transparent flow housing by the laser dopper vibrometer. Pressure drop in-between three measurement distances was measured by the differential pressure transmitter. High frequency vibration and pressure drop fairly depends on the geometric design of supporting structure. So, these two parameters would be used as a qualitative design variables for design evaluation and analysis.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5759-5765
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• 2014

Electrical impedance tomography (EIT) is a potential supplement for mammogram screening. This study aimed to evaluate and feasibility of EIT as opposed to mammography and to determine pain perception with both imaging methods. Women undergoing screening mammography at the Radiology Department of National University of Malaysia Medical Centre were randomly selected for EIT imaging. All women were requested to give a pain score after each imaging session. Two independent raters were chosen to define the image findings of EIT. A total of 164 women in the age range from 40 to 65-year-old participated and were divided into two groups; normal and abnormal. EIT sensitivity and specificity for rater 1 were 69.4% and 63.3, whereas for rater 2 they were 55.3% and 57.0% respectively. The reliability for each rater ranged between good to very good (p<0.05). Quantitative values of EIT showed there were significant differences in all values between groups (ANCOVA, p<0.05). Interestingly, EIT scored a median pain score of $1.51{\pm}0.75$ whereas mammography scored $4.15{\pm}0.87$ (Mann Whitney U test, p<0.05). From these quantitative values, EIT has the potential as a health discriminating index. Its ability to replace image findings from mammography needs further investigation.

• 대한한의학원전학회지
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• 제31권4호
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• pp.27-46
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• 2018

Objectives : In this paper, we investigated the applicability of text mining to Korean Medical Classics and suggest that researchers of Medical Classics utilize this methodology. Methods : We applied text mining to the Huangdi's internal classic, a seminal text of Korean Medicine, and visualized networks which represent connectivity of terms and documents based on vector similarity. Then we compared this outcome to the prior knowledge generated through conventional qualitative analysis and examined whether our methodology could accurately reflect the keyword of documents, clusters of terms, and relationships between documents. Results : In the term network, we confirmed that Qi played a key role in the term network and that the theory development based on relativity between Yin and Yang was reflected. In the document network, Suwen and Lingshu are quite distinct from each other due to their differences in description form and topic. Also, Suwen showed high similarity between adjacent chapters. Conclusions : This study revealed that text mining method could yield a significant discovery which corresponds to prior knowledge about Huangdi's internal classic. Text mining can be used in a variety of research fields covering medical classics, literatures, and medical records. In addition, visualization tools can also be utilized for educational purposes.

• 한국항공우주학회지
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• 제41권10호
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• pp.779-787
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• 2013

항공기 추진 시스템의 IR 피탐지성 감소 연구를 위해 항공기 노즐형상 변화에 따른 IR 신호의 영향성을 연구하였다. 이를 위해 가상의 아음속 무인기를 선정하고, 임무분석 및 성능 해석을 통해 엔진을 결정한 후 전체 임무를 만족시키는 원형 노즐을 설계하였다. 또한 다수의 설계변수를 적용하여 다양한 형상의 노즐을 설계하였다. 압축성 CFD 코드를 이용하여 열유동장 및 노즐표면 온도를 분석하였다. 또한 열유동장 해석 결과를 바탕으로 narrow-band 모델과 RadThermIR을 기반으로 하여 항공기 플룸 및 노즐표면 IR 신호를 계산하였다. 계산된 플룸 및 고체 IR신호를 분석, 비교하여 항공기 IR 신호 특성에 관한 정성적 정보를 도출하였다.

• 한국해안해양공학회지
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• 제7권3호
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• pp.248-256
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• 1995

표층밀도분류에 대한 수치계산에서 문제로 되는 것은 자유수면의 처리, 레이놀즈응력/플럭스항, 특히 난류변동성분에 미치는 부력효과 등에 관련된 것이며, 이것에 대한 보다 집중적인 연구가 필요하다. 또한, 농도장이나 온도장에서의 난류변동성분을 측정하는 데 있어서의 어려움으로 인한 실험자료의 부족으로 수치 계산으로부터 얻어진 예측결과의 충분한 검증은 이루어지지 않고 있다. 본 연구에서는 2차원 표층밀도분류에 대한 유동특성을 조사하기 위하여 난류의 비등방성을 고려하여 난류응력을 직접 계산하는 대수응력모델을 적용하여 수치계산을 행하고, 그 결과를 실험결과와 비교ㆍ검토하였다. 검토한 결과 대수응력모델은 전 영역모델은 전 영역에서 2차원 표층밀도분류의 유동특성을 양호하게 재현하였으며, 특히 부력효과로 인한 성층화가 발생하는 부력 탁월영역에서 난류유동장의 흐름특성을 합리적으로 예측함을 입증하였다.

• 비파괴검사학회지
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• 제26권2호
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• pp.122-129
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• 2006

본 논문에서는 레이저 응용 비파괴검사 기술인 Shearography를 이용하여 압력 배관 내부 결함의 검출에 있어서 미치는 전단량의 영향을 분석하였다. Shearography는 레이저 응용기법에 비하여 환경 외란에 둔감하며, 대상체 표면의 상대 변위를 검출함으로서 비파괴검사 분야에서 많은 활용이 기대된다. 현재까지 연구는 적용 가능성의 평가와 적용 대상의 확대에 중점을 두어 연구가 진행되어 왔으며, 결함의 정량평가를 위해서는 결함 검출에 있어서 영향을 주는 인자들에 대한 연구가 필요하다. 따라서 본 논문에서는 결함의 검출에 영향을 줄 수 있는 전단량의 변화에 따라 결함의 크기 측정과 길함의 위치 결정에 대한 영향을 예측하고, 압력용기 내부의 길이 방향 인공 결함에 대해 적용하여 검출 결과를 분석하였다.

• 생약학회지
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• 제40권2호
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• pp.109-117
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• 2009

We examined the purity of six heparin samples by using heparinase, chondroitinase, $^{1}H-NMR$, and polyacrylamide gel electrophoresis. To obtain high molecular weight contaminants from heparin samples, heparinase I - digested samples were subjected to the exhaustive microcon filtration. The filtration process removed heparin-derived di- and oligosaccharides effectively. By combining chondroitinase ABC treatment and strong anion exchange - high performance liquid chromatography, the result showed all six samples contained chondroitin sulfate as a contaminant ranging from 1.3 to 14.9%. Among them, sample S3 showed the highest content of 14.9%, which was further analyzed by chondroitinase AC treatment to confirm chondroitin sulfate B (dermatan sulfate). $^{1}H-NMR$ chemical shifts of N-acetyl groups clearly suggested the existence of chondroitin sulfate B (sample S3) and oversulfated chondroitin sulfate (samples S2 and S4) as contaminants. In addition, polyacrylamide gel electrophoresis was useful for qualitative detection on the sample's purity. These results suggest that the tools of heparinase I and chondroitinase ABC in combination with NMR spectroscopy would give very useful information for investigation of heparin contaminants such as oversulfated chondroitin sulfate and dermatan sulfate in heparin samples.

• Wind and Structures
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• 제31권3호
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• pp.229-240
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• 2020

In the present work, the main features of primary vortices and the vorticity concentrations downstream of vortex bursting in crossflow plane of a delta wing with a sweep angle of Λ=70° were investigated under the variation of the sideslip angles, β. For the pre-review of flow structures, dye visualization was conducted. In connection with a qualitative observation, a quantitative flow analysis was performed by employing Particle Image Velocimetry (PIV). The sideslip angles, β were varied with four different angles, such as 0°, 4°, 12°, and 20° while angles of attack, α were altered between 25° and 35°. This study mainly focused on the instantaneous flow features sequentially located at different crossflow planes such as x/C=0.6, 0.8 and 1.0. As a summary, time-averaged and instantaneous non-uniformity of turbulent flow structures are altered considerably resulting in non-homogeneous delta wing surface loading as a function of the sideslip angle. The vortex bursting location on the windward side of the delta wing advances towards the leading-edge point of the delta wing. The trajectory of the primary vortex on the leeward side slides towards sideways along the span of the delta wing. Besides, the uniformity of the lift coefficient, C_L over the delta wing plane was severely affected due to unbalanced distribution of buffet loading over the same plane caused by the variation of the sideslip angle, β. Consequently, dissimilarities of the leading-edge vortices result in deterioration of the mean value of the lift coefficient, C_L.

• Journal of Pharmaceutical Investigation
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• 제24권3호
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• pp.115-129
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• 1994

In the present study, quantitative and qualitative histology was used to assess the effects of ibuprofen suppositories with various treatments on the rectal mucosa of rats. Two suppositories were prepared with Witepsol W35 and compared with two commercial ibuprofen suppositories Reference I (Showa Pharm.ind., Tokyo, Japan), Reference II (P.Pharm., Seoul, Korea). Single and multiple dose(dosing interval 4 hr, n=4) studies were conducted. All suppositories significantly increased epithelial cell loss, but the extent of rectal irritation was variable. These studies showed that the incorporation of ibuprofen into the suppository bases increases the morphological change in rectal tissue both for the single and multiple administrations of suppositories, but which was significantly recovered within 24 hr although the interanimal variability in scores was very substantial. Multiple administration of ibuprofen suppositories caused significant damage to rectal mucosa, but it must be considered that these were under the severe condition, that is, interval of administration (4 hr) was three times shorter than normal interval of administration and dose was fifteen times larger than usual human dose. Aluminum oxide $(Al_2O_3)$, a dispersing agent, slightly increased the irritation of rectal mucosa in rats at 5 hr and 24 hr after multiple administration, but it was possible to ignore the difference of irritation in the data at 5hr and 24hr after single administration. Finally, it was concluded that Witepsol W35 and ibuprofen had a slight rectal mucosa-irritating effect on the usual human dose, and ibuprofen suppositories prepared with Witepsol W35 or Witepsol W35, $Al_2O_3$ showed almost similar extent of rectal irritation with commercial ibuprofen products.