• 제목/요약/키워드: Q analysis method

검색결과 938건 처리시간 0.023초

Comparison of QSAR Methods (CoMFA, CoMSIA, HQSAR) of Anticancer 1-N-Substituted Imidazoquinoline-4,9-dione Derivatives

  • Suh, Myung-Eun;Park, So-Young;Lee, Hyun-Jung
    • Bulletin of the Korean Chemical Society
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    • 제23권3호
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    • pp.417-422
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    • 2002
  • Comparison studies of the Quantitative Structure Activity Relationship (QSAR) methods with new imidazo-quinolinedione derivatives were conducted using Comparative Molecular Field Analysis (CoMFA), Comparative Molecular Similarity Indices Analysis (CoMSIA), and the Hologram Quantitative Structure Activity Relationship (HQSAR). When the CoMFA crossvalidation value, q2, was 0.625, the Pearson correlation coefficient, r2, was 0.973. In CoMSIA, q2 was 0.52 and r2 was 0.979. In the HQSAR, q2 was 0.501 and r2 was 0.924. The best result was obtained using the CoMSIA method according to a comparison of the calculated values with the real in vitro cytotoxic activities against human ovarian cancer cell lines.

정밀유도무기 품질관리를 위한 공정관리 수행모델에 관한 연구 (A Study on Process Control Modeling for Precision Guided Munitions Quality Control)

  • 김시옥;이창우;차성희
    • 품질경영학회지
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    • 제41권3호
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    • pp.487-494
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    • 2013
  • Purpose: In this study, we propose the precision guided munitions verification methodology using the statistical analysis method has been proposed. and it can be applied to the precision guided munitions quality assurance work. Methods: This modeling is based on Failure Mode and Effects Analysis, Statistical Process Control, Defense Quality Managerment System, Production Readiness Review, Manufacturing Readiness Assesment and so on. Results: The Process Control Modeling that has the following procedures ; searching the critical to quality, statistical analysis by process, verify process. Moreover, the effectiveness of the methodology is verified by applying to the precision guided munitions. Conclusion: To achieve a analysis methods of statistical process control and verify process for precision guided munitions.

Q방법론에 의한 궁중음식 전문점 조리사 및 운영자의 궁중음식 인식 분석 (Analysis of Korean Restaurant Employees' Perception of Korean Royal Cuisine using Q Methodology)

  • 정서영;정희선
    • 한국조리학회지
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    • 제23권7호
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    • pp.71-79
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    • 2017
  • This paper presented analysis on the perception by Korean restaurant employees of Korean royal cuisine. Classification using a subjective research method called Q methodology was performed on perceptions of Korean restaurant employees about Korean royal cuisine. This paper derived four types of perceptions. First type (pursuit of tradition) emphasized traditions of royal cuisine, i.e. cooking method and spacious menu-setting on the table. The second type (pursuit of refinement) stressed the importance of "atmosphere and luxuriousness of Korean restaurants and sophistication of royal cuisine, as well as the improvement of interior and exterior environments of Korean restaurants serving royal cuisine. The third type (pursuit of fundamentals) focused on fundamentals of royal cuisine itself such as raw materials, sincere effort, historical meaning, appropriate prices, etc. The last type (pursuit of health) valued a nutritionally balanced diet rather than taste itself. This study provides more specific positioning strategy based on the characteristics of each of the four classifications for the status of Korean restaurants.

수심적분법에 의한 유사량 추정연구 (A Study on Estimation by Depth Integrating Method of Sediment Discharge)

  • 서승덕;김활곤;우효섭
    • 한국농공학회지
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    • 제38권1호
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    • pp.90-97
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    • 1996
  • In Korea, total sediment discharge of a river has been estimated simply by using certain sediment transport formulas including, among others, Einstein's formula. Those formular, however, are known not to be reliable enough for the result calculated by them to be used directly to river planning and management. Therefore, the study used the Modified Einstein Procedure to the estimation of total sediment discharge, because this method is reliable estimated by measurement. Here, measurement of sediment discharge used depth integrating method. The major results obtained from the study for estimation by depth integrating method of sediment discharge in Naeseong stream are as follow; 1 The sedeiment characteristics of Naeseong stream are; The distribution of sediment grain size shows that silt and clay are 55% and sand is 45%. and the bed load sediment grain size is constituted that sand contained with the grain size from O.062mm to 2.0mm is 80% 2. The sediment rating formulas derived from the regression analysis between the sediment discharge and flow discharge are; Seogpo-Gyo : Qs=$0.017 \times 10^{-4} Q^{2.352}$, where discharge is l0cms $0.074 \times 10^{-4} Q^{2.066}$, where discharge is l0cms

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철손을 고려한 단상 영구자석형 유도동기기의 특성해석 (Characteristic Analysis of Single-phase Line-start Permanent Magnet Synchronous Motor Considering Iron Loss)

  • 남혁;강규홍;홍정표
    • 대한전기학회논문지:전기기기및에너지변환시스템부문B
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    • 제53권5호
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    • pp.295-304
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    • 2004
  • This paper deals with characteristic analysis method using d-q axis equivalent circuit considering iron loss in a single-phase line-start permanent magnet synchronous motor. The iron loss resistance to account for the iron loss is included in the equivalent circuit to improve the modeling accuracy. Furthermore, for the improved calculation of the iron loss, the iron loss is calculated from the magnetic flux density by 2-dimensional finite element method. The result is represented as the iron loss resistance and connected in parallel with the total induced voltage. Therefore, the currents can be expressed as the summation the output current with the current corresponding to the iron loss. Finally, the steady state characteristic analysis results are compared with the experimental results to verify this approach.

금산 진악산의 산림군락 분류 및 구조 분석 (Classification and Analysis of Community Structure of Jinaksan Forest in Geumsan)

  • 지윤의;이미정;김효정;이규석;이선;송호경
    • 환경생물
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    • 제21권3호
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    • pp.262-270
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    • 2003
  • 본 연구는 충남 금산군에 위치한 진악산 산림식생을 대상으로 식물사회학적 방법으로 산림군락을 분류하고 방형구법으로 임분 특성을 분석하였다. 진악산의 26개 조사구를 분석한 결과, 산림군락은 신갈나무군락, 굴참나무군락, 갈참나무군락 및 소나무군락으로 구분되었으며, 피도율은 교목층이 79.4%, 아교목층이 27.6%, 관목층이 37.0%, 초본층이 31.1%의 순으로 나타났다. DBH 2 cm이상의 수목을 대상으로 중요치를 분석한 결과는 신갈나무가 45.51, 소나무가 44.17, 굴참나무가 27.56, 졸참나무가 26.78, 갈참나무가 20.81, 벚나무가 15.58등의 순으로 나타났으며, 흉고직경급을 분석한 결과 신갈나무, 굴참나무, 갈참나무, 소나무는 5 cm이하의 어린 개체와 15 cm이상의 큰 개체는 적고 5~15cm의 중간 개체가 많아 이들이 당분간 우점할 것으로 판단된다.

A comparison of three performance-based seismic design methods for plane steel braced frames

  • Kalapodis, Nicos A.;Papagiannopoulos, George A.;Beskos, Dimitri E.
    • Earthquakes and Structures
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    • 제18권1호
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    • pp.27-44
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    • 2020
  • This work presents a comparison of three performance-based seismic design methods (PBSD) as applied to plane steel frames having eccentric braces (EBFs) and buckling restrained braces (BRBFs). The first method uses equivalent modal damping ratios (ξk), referring to an equivalent multi-degree-of-freedom (MDOF) linear system, which retains the mass, the elastic stiffness and responds in the same way as the original non-linear MDOF system. The second method employs modal strength reduction factors (${\bar{q}}_k$) resulting from the corresponding modal damping ratios. Contrary to the behavior factors of code based design methods, both ξk and ${\bar{q}}_k$ account for the first few modes of significance and incorporate target deformation metrics like inter-storey drift ratio (IDR) and local ductility as well as structural characteristics like structural natural period, and soil types. Explicit empirical expressions of ξk and ${\bar{q}}_k$, recently presented by the present authors elsewhere, are also provided here for reasons of completeness and easy reference. The third method, developed here by the authors, is based on a hybrid force/displacement (HFD) seismic design scheme, since it combines the force-base design (FBD) method with the displacement-based design (DBD) method. According to this method, seismic design is accomplished by using a behavior factor (qh), empirically expressed in terms of the global ductility of the frame, which takes into account both non-structural and structural deformation metrics. These expressions for qh are obtained through extensive parametric studies involving non-linear dynamic analysis (NLDA) of 98 frames, subjected to 100 far-fault ground motions that correspond to four soil types of Eurocode 8. Furthermore, these factors can be used in conjunction with an elastic acceleration design spectrum for seismic design purposes. Finally, a comparison among the above three seismic design methods and the Eurocode 8 method is conducted with the aid of non-linear dynamic analyses via representative numerical examples, involving plane steel EBFs and BRBFs.

Interstitial deletion of 5q33.3q35.1 in a boy with severe mental retardation

  • Lee, Jin Hwan;Kim, Hyo Jeong;Yoon, Jung Min;Cheon, Eun Jung;Lim, Jae Woo;Ko, Kyong Og;Lee, Gyung Min
    • Clinical and Experimental Pediatrics
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    • 제59권sup1호
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    • pp.19-24
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    • 2016
  • Constitutional interstitial deletions of the long arm of chromosome 5 (5q) are quite rare, and the corresponding phenotype is not yet clearly delineated. Severe mental retardation has been described in most patients who present 5q deletions. Specifically, the interstitial deletion of chromosome 5q33.3q35.1, an extremely rare chromosomal aberration, is characterized by mental retardation, developmental delay, and facial dysmorphism. Although the severity of mental retardation varies across cases, it is the most common feature described in patients who present the 5q33.3q35.1 deletion. Here, we report a case of a de novo deletion of 5q33.3q35.1, 46,XY,del(5)(q33.3q35.1) in an 11-year-old boy with mental retardation; to the best of our knowledge this is the first case in Korea to be reported. He was diagnosed with severe mental retardation, developmental delay, facial dysmorphisms, dental anomalies, and epilepsy. Chromosomal microarray analysis using the comparative genomic hybridization array method revealed a 16-Mb-long deletion of 5q33. 3q35.1(156,409,412-172,584,708)x1. Understanding this deletion may help draw a rough phenotypic map of 5q and correlate the phenotypes with specific chromosomal regions. The 5q33.3q35.1 deletion is a rare condition; however, accurate diagnosis of the associated mental retardation is important to ensure proper genetic counseling and to guide patients as part of long-term management.

Deconvolution 분석(分析)을 이용(利用)한 좌우단락량(左右短絡量) 측정(測定)의 의의(意義) (Radionuclide Quantitation of Left-to-Right Cardiac Shunts Using Deconvolution Analysis)

  • 오연상;이명철;조보연;고창순
    • 대한핵의학회지
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    • 제18권1호
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    • pp.9-17
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    • 1984
  • The purpose of this study is to investigate significance of new method for quantification of left to right cardiac shunts using deconvolution analysis as an adjunct to gamma variate analysis in patients with bad bolus injection. In the present study, quantitative radionuclide angiocardiography (QRAC) was performed with and without deconvolution analysis (DA) in 37 patients with left to right shunt and 103 control patients without shunt. The results obtained were as follows; 1) The mean value of $Q_p/Q_s$ in 103 control patients was $1.10{\pm}0.12$ without DA, and was $1.01{\pm}0.03$ with DA. 2) Correlation(r) between oximetry and QRAC with DA was 0.87 and correlation(r) between oximetry and QRAC without DA was 0.61. 3) The 13 patients with left to right shunt, whose $Q_p/Q_s$ was greater than 3.0 by QRAC without DA, was studied by DA. Then the $Q_p/Q_s$ values were measurable in these 13 patients by DA and they showed significant correlation with oximetry. (r=0.68) The results indicate that deconvolution analysis technique for quantification of a left to right shunt provides more reliable and accurate shunt quantification, and reduces the influences of poor bolus injection.

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8 비트 구현 Ring-LWE 암호시스템의 SPA 취약점 연구 (A Study of SPA Vulnerability on 8-bit Implementation of Ring-LWE Cryptosystem)

  • 박애선;원유승;한동국
    • 정보보호학회논문지
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    • 제27권3호
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    • pp.439-448
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    • 2017
  • 포스트 양자 암호라 할지라도 실제 디바이스에 이를 적용 할 때 부채널 분석 취약점이 존재한다는 것은 이미 알려져 있다. 코드 기반 McEliece 암호와 격자 기반 NTRU 암호에 대한 부채널 분석 연구 및 대응책 연구는 많이 이루어지고 있으나, ring-LWE 암호에 대한 부채널 분석 연구는 아직 미비하다. 이에 본 논문은 8비트 디바이스에서 ring-LWE 기반 암호가 동작할 때 적용 가능한 선택 암호문 SPA 공격을 제안한다. 제안하는 공격은 [$log_2q$]개의 파형으로 비밀키를 복구 할 수 있다. q는 보안 레벨과 관련된 파라미터로 128비트 또는 256비트의 보안 레벨을 만족하기 위해 각각 7681 또는 12289를 사용한다. 또한, 우리는 실제 디바이스에서 동작되는 ring-LWE 복호화 과정의 모듈러 덧셈에서 비밀키를 드러낼 수 있는 취약점이 존재함을 실험을 통해 보이고, 공격 시간 단축을 위한 두 벡터의 유사도 측정 방법을 이용한 공격에 대해 논한다.