• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.70-70
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• 2015

하천에서의 수문/수리적 특성은 주수로의 다양한 지형학적 형태로 나타난다. 특히 흐름과 수반된 유사량의 변화는 하천의 지형학적, 수리기하적 특성을 지배하며, 하도의 물리적 시스템을 변화시켜 동적 평형에 이르게 된다. 하천에서 하도 형성에 지배적인 역할을 하는 수리특성은 하도형성유량으로 지배유량이며, 보통 만제유량을 사용한다. Dunne and Leopold(1978)는 만제유량을 유사의 이송, 하천의 사행, 유선형의 변화 등 하천의 일반적인 형태를 변화시키며, 주수로의 특성을 형성하는 유량으로 정의하였다. 이와 같이 수리 지형학적 특성을 반영하는 만제유량은 하천의 특성을 나타내는 중요한 요소이다. 따라서 본 연구에서는 한강 수계 20개 하천, 27개 수위 관측소의 최소 10년 이상의 실측 자료를 기반으로 다년간의 연평균 실측유량을 산정하였으며, McCandless(2003)가 제시한 지형학적 만제지표를 이용하여 추정한 만제유량과의 상관성을 분석하였다. 추정된 만제유량은 HEC-RAS model을 이용하여 만제하폭, 만제수심, 만제 시 평균유속을 산정하였다. 27개 지점의 실측유량과 만제유량의 상관성 분석결과 만제유량은 연평균 일유량의 7.7배로 나타났다. 따라서 만제유량을 7일 평균유량(1 week mean discharge)으로 정의하였으며, 수정된 7일 유량과 만제유량의 RMSE는 13.90 m/s, MAPE는 9.94 %로 상관성이 매우 높게 나타났다. 또한 만제유량과 만제하폭, 만제수심, 평균유량, 구간경사와 상관성 분석결과 개별적으로의 상관성은 나타나지 않았으나, 만제하폭, 수심, 평균유량과 만제유량에 대한 회귀 분석을 실시한 결과 $R^2$는 0.911로 매우 높게 나타났으며, 구간경사를 추가하여 분석한 결과 $R^2$가 0.914로 증가하였다. 따라서 만제유량은 수리 기하학적 특성이 모두 반영된 하천 특성을 나타내는 복합적인 지표임을 확인하였다. 아울러 만제유량을 통해 추정된 연평균 유량($48{\cdot}Q_{bf}$)을 우리나라의 월간 유출량 분포 비율을 이용하여 일유량으로 배분/생성하였으며, 생성된 일유량을 통해 CCHE2D model을 이용하여 하상변동 모의를 수행하였다. 대상 구간은 병성천 최하류로부터 상류로 7 km 구간이며, 2013년 1월과 12월 측량 자료를 통한 1년간의 실제 하상 변동 자료와 2013년 실측 유량자료에 따른 하상변동 모의 결과 및 만제유량에 의해 배분/생성된 일유량에 따른 하상변동 모의 결과를 비교하였다. 비교 분석 결과 7일 평균 유량으로 정의된 만제유량을 통해 배분/생성된 유량의 수치모의 결과는 실제 측량자료 및 실측유량자료에 따른 하상변동 결과와 매우 일치하는 것을 확인하였다.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.580-580
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• 2015

하천에서의 수문/수리적 특성은 주수로의 다양한 지형학적 형태로 나타난다. 특히 흐름과 수반된 유사량의 변화는 하천의 지형학적, 수리기하적 특성을 지배하며, 하도의 물리적 시스템을 변화시켜 동적 평형에 이르게 된다. 하천에서 하도 형성에 지배적인 역할을 하는 수리특성은 하도형성 유량으로 지배유량이며, 보통 만제유량을 사용한다. Dunne and Leopold(1978)는 만제유량을 유사의 이송, 하천의 사행, 유선형의 변화 등 하천의 일반적인 형태를 변화시키며, 주수로의 특성을 형성하는 유량으로 정의하였다. 이와 같이 수리 지형학적 특성을 반영하는 만제유량은 하천의 특성을 나타내는 중요한 요소이다. 따라서 본 연구에서는 한강 수계 20개 하천, 27개 수위 관측소의 최소 10년 이상의 실측 자료를 기반으로 다년간의 연평균 실측유량을 산정하였으며, McCandless(2003)가 제시한 지형학적 만제지표를 이용하여 추정한 만제유량과의 상관성을 분석하였다. 추정된 만제유량은 HEC-RAS model을 이용하여 만제하폭, 만제수심, 만제 시 평균유속을 산정하였다. 27개 지점의 실측유량과 만제유량의 상관성 분석결과 만제유량은 연평균 일유량의 7.7배로 나타났다. 따라서 만제유량을 7일 평균유량(1 week mean discharge)으로 정의하였으며, 수정된 7일 유량과 만제유량의 RMSE는 13.90m/s, MAPE는 9.94 %로 상관성이 매우 높게 나타났다. 또한 만제유량과 만제하폭, 만제수심, 평균유량, 구간경사와 상관성 분석결과 개별적으로의 상관성은 나타나지 않았으나, 만제하폭, 수심, 평균유량과 만제유량에 대한 회귀 분석을 실시한 결과 $R^2$는 0.911로 매우 높게 나타났으며, 구간경사를 추가하여 분석한 결과 $R^2$가 0.914로 증가하였다. 따라서 만제유량은 수리 기하학적 특성이 모두 반영된 하천 특성을 나타내는 복합적인 지표임을 확인하였다. 아울러 만제유량을 통해 추정된 연평균 유량($48{\cdot}Q_{bf}$)을 우리나라의 월간 유출량 분포 비율을 이용하여 일유량으로 배분/생성하였으며, 생성된 일유량을 통해 CCHE2D model을 이용하여 하상변동 모의를 수행하였다. 대상 구간은 병성천 최하류로부터 상류로 7 km 구간이며, 2013년 1월과 12월 측량 자료를 통한 1년간의 실제 하상 변동 자료와 2013년 실측 유량자료에 따른 하상변동모의 결과 및 만제유량에 의해 배분/생성된 일유량에 따른 하상변동 모의 결과를 비교하였다. 비교 분석 결과 7일 평균 유량으로 정의된 만제유량을 통해 배분/생성된 유량의 수치모의 결과는 실제 측량자료 및 실측유량자료에 따른 하상변동 결과와 매우 일치하는 것을 확인하였다.

• Journal of Korean Medicine for Obesity Research
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• v.3 no.1
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• pp.7-16
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• 2003

Objectives : The lipolytic effects of catecholamines in adipose tissue are mediated by members of adrenergic receptors. This study was conducted to examine the effects of ${\beta}2-AR$ Gln27Glu (Q27E) polymorphism on obesity indices and risk among obesity clinic patients. Methods : 532 subjects, 38 men and 494 women, who attended a weight loss program in a local obesity clinic were analyzed. Height, weight, BMI, WHR and obesity index were measured or calculated. Body composition was measured by bio-impedance analysis. Genotype of ${\beta}2-AR$ polymorphism in codon 27 was analyzed by PCR-RFLP method. Serum concentrations of fasting glucose, total and HDL cholesterol, and triglyceride were determined by autobiochemical analyzer. Results: The Genotype distributions of ${\beta}2-AR$ gene were QQ type 81.3%, QE type 17.9% and EE type 8%. Therefore, the frequency of E allele of ${\beta}2-AR$ gene was 0.170 in the total subjects. The frequency of the ${\beta}2-AR$ variant genotype(QE+EE) was significantly higher in obese group($BMI{\geqq}25$) compared with non-obese group(p=0.027). Weight was significantly higher in variant(QE+EE) type compared with normal(QQ) type in total subjects(p=0.001), male(p=0.022) and female(p=0.013). BMI, obesity index and WHR were also significantly higher in QE+EE type. Body fat man was significantly higher in QE+EE type in total subjects(p=0.005) and female(p=0.027). When forward stepwise regression analysis was used to create a model of risk predictors of obesity($BMI{\geqq}25$), QE+EE type of ${\beta}2-AR$ gene was found to be a significant risk factor for obesity (p=0.042, ORs 1.597). Conclusions: QE+EE genotype of ${\beta}2-AR$ was associated with increased obesity indices and might be a significant risk factor for obesity.

• Korean Journal of Optics and Photonics
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• v.16 no.5
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• pp.469-475
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• 2005

An integrated photonic microwave bandpass filter has been proposed and demonstrated incorporating a coherently coupled microring resonator in low-loss polymers. The proposed device may feature compact site, simple structure, tuning via the thermooptic and electrooptic effect, and flexible integration with other electrical and optical devices. The resonator was designed to have an extremely small bandwidth so that it could be used to selectively pass the optical signal carrying the microwave signal to attain efficient bandpass filtering. We made and tested two resonators with a single ring and double rings, and performed a theoretical fitting of their measured transfer curves to predict the performance of the microwave filters based on them precisely. It was found that as the number of the rings used for the resonator increases, the bandwidth gets smaller, the rolloff sharper, and the band rejection higher. Finally our filter exhibited the center frequency of 10GHz, the 3-dB bandwidth of 1.0GHz, the corresponding quality (Q) factor of 10, and the rejection outside of the passband of more than 25dB.

• Journal of Soil and Groundwater Environment
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• v.21 no.1
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• pp.28-39
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• 2016

Struvite (MgNH₄PO₄ ⋅ 6H₂O) and hydroxyapatite (HAP, Ca₁₀(PO₄)₆(OH)₂) precipitation in urine-separating toilets (NoMix toilets) causes severe maintenance problems and also reduce the phosphate and calcium content. Application of urine separating technique and extraction of by-products from human urine is a cost effective technique in waste water treatment. In this study, we extract urine calcite from human urine by batch scale method, using urease producing microbes to trigger the precipitation and calcite formation process. Extracted urine calcite (calcining at 800℃) is a potential adsorbent for removal of heavy metal(loid)s like (Cd²⁺, Cu²⁺, Ni²⁺, Pb²⁺, Zn²⁺ and As³⁺) along with additional leaching analysis of total nitrogen (T-N), phosphate (T-P) and chemical oxygen demand (COD). The transformations of calcite during synthesis were confirm by characterization using XRD, SEM-EDAX and FT-IR techniques. In additional, the phosphate leaching potential and adsorbate (nitrate) efficiency in aqueous solution was investigated using the calcinedurine calcite. The results indicate that the calcite was effectively remove heavy metal(loid)s lead up to 96.8%. In addition, the adsorption capacity (q_e) of calcite was calculated and it was found to be 203.64 Pb, 110.96 Cd, 96.02 Zn, 104.2 As, 149.54 Cu and 162.68 Ni mg/g, respectively. Hence, we suggest that the calcite obtain from the human urine will be a suitable absorbent for heavy metal(loid)s removal from aqueous solution.

• Journal of Veterinary Science
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• v.22 no.5
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• pp.62.1-62.13
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• 2021

Background: Canine mammary gland tumor (MGT) is the most common cancer in aged female dogs. Although it's important to identify reliable metastasis or prognostic factors by evaluating related to cell division, adhesion, and cancer stem cell-related transcription factor (TF) in metastasis-induced canine MGT, but there are limited studies. Objectives: We aimed to identify metastasis prognostic factors and cancer stem cell-TFs in canine MGTs. Methods: Age-matched female dogs diagnosed with MGT only were classified into metastatic and non-metastatic groups by histopathological staining of MGT tissues. The mRNA levels of cancer prognostic metastasis molecular factors (E-cadherin, ICAM-1, PRR14, VEGF, HPRT1, RPL4 and hnRNP H) and cancer stem cell-related TFs (Oct4, Sox2, and Nanog) were compared between metastatic and non-metastatic canine MGT tissues using qRT-PCR analysis. Results: The mRNA levels of ICAM-1, PRR14, VEGF, hnRNP H, Oct4, Sox2, and Nanog in metastatic MGT group were significantly higher than those in non-metastatic MGT group. However, mRNA level of RPL4 was significantly lower in metastatic MGT group. Loss of E-cadherin and HPRT1 was observed in the metastatic MGT group but it was not significant. Conclusions: Consistent expression patterns of all metastasis-related factors showing elevation in ICAM-1, PRR14, VEGF, hnRNP H, Oct4, Sox2, and Nanog, but decreases in RPL4 levels occurred in canine MGT tissues, which was associated with metastasis. Thus, these cancer prognostic metastasis factors and TFs of cancer stem cells, except for E-cadherin and HPRT1, can be used as reliable metastasis factors for canine MGT and therapeutic strategy.

• Composites Research
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• v.34 no.5
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• pp.311-316
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• 2021

In this study, TiC/steel metal matrix composites were fabricated by powder metallurgy process using Fealloy powders with 3 wt.% Cr and 10 wt.% Cr, respectively, as matrix material. Subsequently, the composite samples were heat treated by the annealing and quenching-tempering(Q-T), respectively, to understand the effect of heat treatment on the mechanical properties of the composites. The correlation between microstructure and structural strength depending on the chromium content and the heat treatment conditions was studied through tensile, compressive, and transverse rupture test and microstructural analysis. In the case of TiC/steel composite containing 10 wt.% Cr, the tensile strength and transverse rupture strength at room temperature were significantly lowered by the influence of coarse chromium carbide formed at the TiC/steel interface. On the other hand, both TiC/steel composites containing 3 wt.% Cr and 10 wt.% Cr showed much higher compressive strength of about 4 GP after quenching-tempering compared to the annealed specimens regardless of the presence of the chromium carbide.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.2
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• pp.83-92
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• 2021

Purpose : Keratinocytes are the main cellular components involved in wound healing during re-epithelization and inflammation. Dysfunction of tight junction (TJ) adhesions is a major feature in the pathogenesis of various diseases. The purpose of this study was to identify the various effects of a Sparassis crispa water extract (SC) on HaCaT cells and to investigate whether these effects might be applicable to human skin. Methods : We investigated the effectiveness of SC on cell HaCaT viability using MTS. The antioxidant effect of SC was analyzed by comparing the effectiveness of ABTS to that of the well-known antioxidant resveratrol. Reverse-transcription quantitative polymerase chain reaction (qRT-PCR) is the most widely applied method Quantitative RT-PCR analysis has shown that SC in HaCaT cells affects mRNA expression of tight-junction genes associated with skin moisturization. In addition, Wound healing is one of the most complex processes in the human body. It involves the spatial and temporal synchronization of a variety of cell types with distinct roles in the phases of hemostasis, inflammation, growth, re-epithelialization, and remodeling. wound healing analysis demonstrated altered cell migration in SC-treated HaCaT cells. Results : MTS analysis in HaCaT cells was found to be more cytotoxic in SC at a concentration of 0.5 mg/㎖. Compared to 100 µM resveratrol, 4 mg/㎖ SC exhibited similar or superior antioxidant effects. SC treatment in HaCaT cells reduced levels of claudin 1, claudin 3, claudin 4, claudin 6, claudin 7, claudin 8, ZO-1, ZO-2, JAM-A, occludin, and Tricellulin mRNA expression by about 1.13 times. Wound healing analysis demonstrated altered cell migration in SC-treated HaCaT cells and HaCaT cell migration was also reduced to 73.2 % by SC treatment. Conclusion : SC, which acts as an antioxidant, reduces oxidative stress and prevents aging of the skin. Further research is needed to address the effects of SC on human skin given the observed alteration of mRNA expression of tight-junction genes and the decreased the cell migration of HaCaT cells.

• Korean Journal of Environment and Ecology
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• v.35 no.2
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• pp.204-219
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• 2021

This study was conducted to investigate and analyze the characteristics of the plant community structure of vegetation distributed on the western slope and ridge connecting Mt. Noja to Mt. Gara. This basic research was executed not only to restore and manage forest vegetation, but also to monitor the trend of change in the long term. As a result of classifying the communitise in 86 survey quadrats, the Pinus thunbergii-Platycarya strobilacea comm. and P. thunbergii-P. densiflora comm. were distributed around the lowlands. The Carpinus tschonoskii-Deciduous broad-leaved comm., Styrax japonicus-Deciduous broad-leaved comm., Acer pictum subsp. Mono-Deciduous broad-leaved comm., Deciduous broad-leaved comm., and Zelkova serrata comm. appeared in the valley and all stone areas. Quercus serrata comm., Q. serrata-S. japonicus comm., S. japonicus-Carpinus cordata comm., Euonymus oxyphyllus comm. were classified as being distributed on steep slopes with relatively high altitude. According to the succession trend of the forest, evergreen conifers will be transition to deciduous broad-leaved trees. However, deciduous broad-leaved arboreous forests, such as Carpinus tschonoskii, zelkova serrata, and Acer pictum subsp. Mono, were considered to maintain their current succession stage because not only the stratified structure was developed over about 50 years tree age, but also ecologically stabilized. As environmental factors, it was analyzed that altitude, pH, content of clay and silt, Mg⁺⁺, Ca⁺⁺, etc. directly or indirectly affect the distribution of plant communities.

• International journal of advanced smart convergence
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• v.10 no.4
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• pp.241-255
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• 2021

The human auricle is the first part to receive sound from the outside. In this part, the frequency range of human recognizable form is divided and organized. In this study, we propose modeling by applying a single sound source to the surface of the human auricle. This means that when the sound pressure of a low frequency (low frequency) sound enters the pinna, the impedance felt at the tip of a part of the non-linear surface of the pinna is mainly due to the tensile force at the end of the part of the non-linear surface of the pinna. By expressing the situation of moving at a very small speed, the characteristic impedance of the pinna was confirmed to be negative infinity, and it was also confirmed that the speed at the tip of a part of the non-linear surface of the pinna was 0 in the anti-resonance state. It was found that the wave propagation phenomenon that determines the characteristics of the filter is determined by how large the wavelength, kL, is compared to the length of the tip of a part of the non-straight surface of the pinna. Humans first receive sounds from outside through their ears. The auricle is non-linear and has a curved shape, and it is known that it analyzes frequencies while receiving external sounds. The human ear has an audible frequency range of 20Hz - 20,000Hz. Through the study, we applied the characteristics of the notch filter to hypothesize that the human audible frequency range is separated from the auricle, and applied filter theory to analyze it, and as a result, meaningful results were obtained. The curved part and the inner part of the auricle function as a trumpet, collecting sounds, and at the same time amplifying the weak sound of a specific band. The point was found and the shape of the envelope detected in the auricle was found. Selectivity for selecting sounds coming from the outside is the formula of the pinna that implements the function of Q. The function of distinguishing human-recognizable sound from the pinna from low to high through frequency analysis is performed in the pinna, and the 2-3kHz area, where human hearing threshold is the most sensitive, is also the acoustic impedance of the most recessed area of the pinna. It can be seen that starting from.