• 제목/요약/키워드: Pyrazoloimidazo-pyridines and pyrimidines

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Novel Synthesis of Imidazo[1,2-b]Pyrazoles and Their Fused Derivatives

  • Sherif, Sherif-M.;Hussein, Abdel-HaLeem-M.;El-kholy, Yehya-M.
    • Archives of Pharmacal Research
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    • 제17권5호
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    • pp.298-303
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    • 1994
  • 4-Arylazo-1H-pyrazol-3, 5-idimines 1a-c reacted with bromomalononitrile (2) to yield the corresponding imidazo[1, 2-b]pyrazoles 3a-c. The latter reacted with some active methylene compounds and with .alpha.-cinnamonitriles to afford the corresponding pyrazoloimidazopyridines 6, 8, 9 and 15, respectively. Compounds 3 reacted with each of formic acid, formamide, trichlo-roacetonitrile and with guanidine to yield the corresponding pyrazoloimidazopyrimidines 16-19 respectively.

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