Seo, Young Woo;Jang, Tae Chang;Kim, Gyun Moo;Ko, Seung Hyun
Journal of The Korean Society of Clinical Toxicology
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v.16
no.2
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pp.157-160
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2018
Chronic silica nephropathy has been associated with tubulointerstitial disease, immune-mediated multisystem disease, chronic kidney disease, and end-stage renal disease. On the other hand, acute intentional exposure is extremely rare. The authors' experienced a 44-year-old man who took rapid cement hardener (sodium silicate) in a suicide attempt whilst in a drunken state. He visited the emergency department approximately 1 hour after ingestion. Information on the material was obtained after 3 L gastric lavage. The patient complained of a sore throat, epigastric pain, and swollen to blood tinged vomitus. Proton pump inhibitors, hemostats, steroid, and fluids were administered. Nine hours after ingestion, he was administered 200 mL hematochezia. Immediately after, a gas-troenterologist performed an endoscopic procedure that revealed diffuse hyperemic mucosa with a color change and variable sized ulceration in the esophagus, whole stomach, and duodenal $2^{nd}$ portion. Approximately 35 hours later, persistent oligouria and progressive worsening of the renal function parameters (BUN/Cr from 12.2/1.2 to 67.5/6.6 mg/dL) occurred requiring hemodialysis. The patient underwent 8 sessions of hemodialysis for 1 month and the BUN/Cr level increased to 143.2/11.2 mg/dL and decreased to 7.6/1.5 mg/dL. He was discharged safely from the hospital. Follow up endoscopy revealed a severe esophageal stricture and he underwent endoscopic bougie dilatation. Acute cement hardener (sodium silicate) intoxication can cause renal failure and strong caustic mucosal injury. Therefore, it is important to consider early hemodialysis and treatment to prevent gastrointestinal injury and remote esophageal stricture.
Liquid hydrogen (LH2) has a higher density than gaseous hydrogen, so it has high transport efficiency and can be stored at relatively low pressure. In order to use efficient bulk hydrogen in the industry, research for the LH2 supply system is needed. In the high-pressure hydrogen station based on LH2 currently being developed in Korea, a heat exchanger is used to heat up supercritical hydrogen at 700 bar and 60 K, which is pressurized by a cryogenic high-pressure pump, to gas hydrogen at 700 bar and 300 K. Accordingly, the heat exchanger used in the hydrogen station should consider the design of high-pressure tubes, miniaturization, and freezing prevention. A helical heat exchanger generates secondary flow due to the curvature characteristics of a curved tube and can be miniaturized compared to a straight one on the same heat transfer length. This paper evaluates the heat transfer performance through parametric study on the distance between coils, guide effect, and anti-icing design of helical heat exchanger. The helical heat exchanger has better heat transfer performance than the straight tube exchanger due to the influence of the secondary flow. When the distance between the coils is uniform, the heat transfer is enhanced. The guide between coils increases the heat transfer performance by increasing the heat transfer length of the shell side fluid. The freezing is observed around the inlet of distribution tube wall, and to solve this problem, an anti-icing structure and a modified operating condition are suggested.
The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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v.12
no.3
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pp.239-243
/
2007
Presence of bottom water nitrite in the Ulleung Basin was remarkable because it is totally unexpected phenomenon at such an oxygen-rich environment. Yet no scientific explanation was set forward. Of several plausible explanations, following the Ockham's suggestion, a leaching of nitrite as an intermediate product of denitrification in the top sediment at the slope is most agreeable to given environmental settings. There seems no complementary process to make up the loss of N in the Ulleung Basin, which seems contribute to the characteristically low N:P ratio in the deep waters. If warming proceeds that weakens the thermohaline circulation, a current biological pump may stall and the phytoplankton assemblage might replaced drastically. If so this will pause an utmost challenge to the ecosystem of the East/Japan Sea. Still there remains a contradictory sedimentary signature that requests further explanation regarding the N (or organic C)-cycle such as extraordinarily high organic carbon content despite abundant oxidants in the overlying waters.
Jung-Man Namgoong;Shin Hwang;Hyunhee Kwon;Suhyeon Ha;Kyung Mo Kim;Seak Hee Oh;Seung-Mo Hong
Annals of Hepato-Biliary-Pancreatic Surgery
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v.26
no.1
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pp.69-75
/
2022
Backgrounds/Aims: Progressive familial intrahepatic cholestasis (PFIC) is an autosomal recessive inherited disease requiring liver transplantation (LT). The objective of this study was to investigate the clinicopathological features and posttransplant courses of seven LT recipients with PFIC. Methods: This was a retrospective single-center study of patients with PFIC who underwent LT from January 2013 to June 2020. Results: Two and five patients were diagnosed with PFIC type 1 and type 2, respectively. For all seven patients, age of PFIC onset was at birth. Jaundice was present in all cases. Mean pretransplant total and direct bilirubin levels were 16.1 ± 8.1 mg/dL and 12.4 ± 6.2 mg/dL, respectively. Median patient age and body weight at LT were 10 months and 7 kg, respectively. Types of donors were mothers of patients in four and deceased donors in three. All five patients with PFIC type 2 recovered uneventfully. One patient each with PFIC type 1 underwent retransplantation due to graft failure or died due to multi-organ failure. Overall graft and patient survival rates at five years were 66.7% and 83.3%, respectively. Bile salt export pump immunohistochemical staining showed normal canalicular expression in two patients with PFIC type 1, focal loss in two patients with PFIC type 2, and total loss in three patients with PFIC type 2. Conclusions: LT is currently the only effective treatment for PFIC-associated end-stage liver diseases. It is mandatory to perform regular follow-up due to the risk of complications including steatohepatitis, especially for patients with PFIC type 1.
This paper examines the epistemology of the body and the direction of Christian education based on it. Looking at Merleau-Ponty, Damagio, and Nelson's epistemology of the body, it found that they had a common point, even though they studied in different areas like philosophy, brain science, and body theology; the body is a subject that perceives the world in a sensuous and direct way, and is a channel that mediates humans and the world, and plays a decisive role in human self-formation. In particular, theology of body revealed, that the body is a pathway for our understanding of God just as a pathway for our understanding the world. In addition, theology of body revealed that the body is regarded as the place of 'embodiment of God', and in the end, the world in which our incarnated body participates should also become the place of 'God's incarnation'. It also examined Christian education based on the epistemology of the body, focusing on 'education starting from the senses', 'education as a participation', and 'incarnational education'. From these three concepts, it found that epistemology of body suggests an alternative view of traditional knowledge-based education or schooling education. It suggests an open paradigm centered on sense and experience, personal participation, non-verbal experience, and field of education, beyond a fixed and closed paradigm of doctrine-centered, objective knowledge mediation, language-centered, and content-centered. Furthermore, this paper found that the body is like a well that can pump up metaphors that provide a basic metaphor for re-conceptualizing Christian education.
This study aims to solve the entangled loop between demographic transition (DT) and economic growth by analyzing cross-country data. We undertake a national-level group analysis to verify the compressed transition of demographic variables over time. Assuming that the LA (latecomer advantage) on DT over time exists, we verify that the DT of the latecomer is compressed by providing a formal proof of LA on DT over income. As a DT has the double-kinked functions of income, we check them in multiple aspects: early maturation, leftward threshold, and steeper descent under a contour map and econometric methods. We find that the developing countries (the latecomer) have speedy DT (CDT, compressed DT) as well as speedy income such that DT of the latecomers starts at lower levels of income, lasts for a shorter period, and finishes at the earlier stage of economic development compared to that of developed countries (the early mover). To check the balance of DT, we classify countries into four groups of DT---balanced, slow, unilateral, and rapid transition countries. We identify that the main causes of rapid transition are due to the strong family planning programs of the government. Finally, we check the effect of latecomer's CDT on economic growth inversely: we undertake the simulation of the CDT effect on economic growth and the aging process for the latecomer. A worrying result is that the CDT of the latecomer shows a sharp upturn of the working-age population, followed by a sharp downturn in a short period. Compared to early-mover countries, the latecomer countries cannot buy more time to accommodate the workable population for the period of demographic bonus and prepare their aging societies for demographic onus. Thus, we conclude that CDT is not necessarily advantageous to developing countries. These outcomes of the latecomer's CDT can be re-interpreted as follows. Developing countries need power sources to pump up economic development, such as the following production factors: labor, physical and financial capital, and economic systems. As for labor, the properties of early maturation and leftward thresholds on DTs of the latecomer mean that demographic movement occurs at an unusually early stage of economic development; this is similar to a plane that leaks fuel before or just before take-off, with the result that it no longer flies higher or farther. What is worse, the property of steeper descent represents the falling speed of a plane so that it cannot be sustained at higher levels, and then plummets to all-time lows.
Geothermal heat pump system (GHPS) is an energy-efficient technology that use the relatively constant and renewable energy stored in the earth to provide heating and cooling. With the aim of using GHPS as a heating source, it's possibilities of application in farrowing house were examined by measuring environmental assessment and sow's performance. A total of 96 sows were assigned to 2 pig housings (GHPS and conventional housing) with 48 for four weeks in winter season. During the experimental period, indoor maximum temperature in GHPS-housing was measured up to $26.7^{\circ}C$, average temperature could maintain $21.2^{\circ}C$. The mean value of dust levels and $CO_2$, $NH_3$ and $H_2S$ gas emissions were decreased in GHPS-housing compare with those of conventional housing. Litter size, birth weight, parity and weaning weight did not differ between housings. However, feed intake of sow in GHPS-housing was lower than that of conventional housing. In energy consumption for heating, electric power consumption increased in GHPS-housing than the conventional housing, a 2,250 kwh increase, whereas there is no fuel usage for heater in GHPS-housing. Amount of ground water circulated for heating in cold weather for earth heat exchanger was 8.4-12.9 ton per day. In conclusion, GHPS may have environmental benefits and effectiveness of heating in farrowing housing and affect the performance in sows.
To understand the effects of the powdered manganese nodule and sea bottom sediment pumped up with nodules on the mining process, the shattering ratio of manganese nodule and their physical properties are analyzed. The self shattering ratio and crushing shattering ratio are about 27% and about 3%, respectively. Then total shattering ratio is about 30%. The initial turbidity of the powdered manganese nodule and the bottom sediment show high, i.e., about 3,100 and 1,850 respectively. But their turbidities decrease rapidly with time. After 1 hour, turbidity of the powdered manganese nodule drops to about 1,570 and that of the bottom sediment to 1,310. The turbidity of Na-bentonite changes from 820 to 730 after 1 h and to 700 after 2 h. The viscosity of powdered manganese nodule is $1.4{\sim}1.5cP$, and the viscosity of bottom sediment is less than 1 cP. The viscosity fo Na-bentonite is initially 37.2 and increase with time to 86.4 cP after 30 min. The high initial turbidity of powdered manganese nodule is due to dark color of the powder. The high specific gravity makes rapid precipitation and then decreases the turbidity rapidly. The bottom sediment shows high initial turbidity because of easy suspension with very fine particle size. But it cannot be hydrated and formed gel in suspension, then it is easily precipitated. However Na-bentonite is hydrated to the expended state and makes gel state, then it shows high turbidity and high viscosity. These physical properties of the powdered manganese nodule suggest that the powder of manganese nodule should not make scaling inside of lifting pipe or pump. And the bottom sediment lifted up with manganese nodule should not play the role of drilling mud shch as Na-bentonite.
KSCE Journal of Civil and Environmental Engineering Research
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v.39
no.6
/
pp.779-788
/
2019
The compaction grouting method is one of the conventional ground improvement methods, which consolidates and compacts the surrounding ground through the injection of grout materials with low mobility. Injecting the grout into the ground can improve the soil properties, as well as form a composite of soil-grout columns. However, the conventional grout pumping is not applicable to handle multiple injection holes at the same time, which may diminish its constructability when the construction time is not enough. This paper proposes a simultaneous multiple compaction-grouting method using a new pump system developed to cover up simultaneously three injection holes at a time. Field injection tests with a single injection hole and with triangular arrangement of injection holes were conducted to evaluate the applicability of the proposed method to soft clay ground. In addition, a series of standard penetration tests (SPTs) were performed to assess the efficiency of each arrangement in improving the soft ground. It is noted from the in-situ test results that the interval distances between injection holes and the elapse time for ground stabilization are the crucial factors governing the applicability of the simultaneous multiple compaction-grouting method to improve the soft clay ground.
To improve the crossflow untrafiltration flux, we applied periodic oscillations in transmembrane pressure gradient in order to promote fluid turbulence by inducing repeated compression and relaxation of the cake/gel layer. The oscillatory forms used were square-, sine-, triangle-wave, and pumping interruption. The permeate flux profiles were mathematically simulated and compared with the experimental data. The result showed the periodic pumping interruption most effectively improved the overall flux by up to about 32%. Enough pumping off-time, at least on the order of tens of seconds, was needed to allow the solutes in the layer to diffuse back to the bulk phase. It was better to start the oscillations earlier before the layer was fully established. The square-wave oscillation yielded about 11% increase, which was particularly pronounced in the later part of the filtration. Either the amplitude or the period of the oscillations resulted little influence on flux.actate ester, and lactate ester produced in esterification reaction was distilled simultaneously with hydrolysis reaction into lactic acid. When the yields of lactic acid recovered by batch reactive distillations with various alcohols were compared, the yield of lactic acid was increased as the volatility of lactate ester was increased. In this batch reactive distillation, because the mixtures condensed in partial condensor were flown to reboiler through distillation column, the recovery yield of lactic acid was affected by operation temperature of partial condensor. Hydrolysis reaction into lactic acid in distillation column rarelyoccurred because of short retention time of lactate ester and water. Lactate ester was reacted into lactic acid in reboiler.
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