• Title/Summary/Keyword: Pulse sequence

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Magnetic resonance imaging characteristic of lymph nodes: Comparison of T1 and T2 weighted image in normal rabbits (림프절의 자기공명영상의 특징: 가토에서 T1과 T2 강조영상의 비교)

  • Lee, Ki-chang;Choi, Min-cheol;Choi, Ho-Jung;Yoon, Jung-hee;Choi, Seong-hong;Moon, Woo-kyung;Chung, Jin-Wook
    • Korean Journal of Veterinary Research
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    • v.44 no.2
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    • pp.311-315
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    • 2004
  • The detection of lymph node metastasis is an important step in tumor staging and is significant for therapy planning. It has been challenged to yield an appropriate image with diagnostic methods such as Magnetic Resonance (MR) and Computed Tomography (CT). Though CT has been used widely and accessed easily to show internal organs, it can hardly provide difference between lymph node and adjacent vessel or fat tissue. It has been well established that MR can reveal the subtle discrepancy within soft tissue. This study investigated the suitability of MR lymph node imaging without contrast enhancement by comparison of T1-weighted image (T1WI) and T2- weighted image (T2WI) in ten normal rabbits. According to the pulse sequence optimized from preliminary study, T1-weighted spin-echo (repetition time/echo time=400/12 ms) and T-2 weighted fast spin-echo (repetition time/echo time=3500/84 ms) images covering the hind limbs and pelvic region were acquired at 1.5 T. Two radiologists scrupulously evaluated the MR images in consensus. And signal intensity of lymph nodes was compared with that of adjacent fat. Statistical analysis showed that T1-weighted coronal image visualized the lymph nodes (iliac, superficial inguinal and popliteal lymph nodes) quickly and consistently rather than T2-weighted one. Conclusively, T1WI for evaluation of lymph nodes is moderately better than T2WI and appears to have potential for quick and sufficient mapping of the lymph nodes. In addition, this normal MR image of lymph nodes could be applied to further study for the evaluation of lymphatic system in abscess and tumor bearing animal model.

Clinical and Experimental Applications of $^1$H MRS (양성자 자기공명분광법의 임상과 실험응용)

  • Choe, Bo-Young;Lee, Hyoung-Koo;Suh, Tae-Suk;Shinn, Kyung-Sub
    • Progress in Medical Physics
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    • v.7 no.1
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    • pp.37-52
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    • 1996
  • Image-guided localized, water-suppressed in vivo $^1$H MR spectroscopic studies were performed on the patients with brain tumors, acute cerebral infarction and schizophrenia, and dogs. GE Signa 1.5 T whole-body MRI/MRS system using STEAM pulse sequence was used. Proton metabolite ratios relative to creatine (Cr) were obtained using a Marquart algorithm. In vivo $^1$H MR spectra in brain neoplastic tissues revealed the changes of signal intensities of N-acetylaspartate (NAA), choline (Cho) and lactate (Lac) resonances. The present results suggest that the observed metabolite alterations from localized, water-suppressed in vivo $^1$H MR spectroscopy can be useful as an index of brain tumors, cerebral infarction and schizophrenia, and provide good quality metabolic information of cerebral tissue in the field of thanato-chronology.

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Image Denoising for Metal MRI Exploiting Sparsity and Low Rank Priors

  • Choi, Sangcheon;Park, Jun-Sik;Kim, Hahnsung;Park, Jaeseok
    • Investigative Magnetic Resonance Imaging
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    • v.20 no.4
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    • pp.215-223
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    • 2016
  • Purpose: The management of metal-induced field inhomogeneities is one of the major concerns of distortion-free magnetic resonance images near metallic implants. The recently proposed method called "Slice Encoding for Metal Artifact Correction (SEMAC)" is an effective spin echo pulse sequence of magnetic resonance imaging (MRI) near metallic implants. However, as SEMAC uses the noisy resolved data elements, SEMAC images can have a major problem for improving the signal-to-noise ratio (SNR) without compromising the correction of metal artifacts. To address that issue, this paper presents a novel reconstruction technique for providing an improvement of the SNR in SEMAC images without sacrificing the correction of metal artifacts. Materials and Methods: Low-rank approximation in each coil image is first performed to suppress the noise in the slice direction, because the signal is highly correlated between SEMAC-encoded slices. Secondly, SEMAC images are reconstructed by the best linear unbiased estimator (BLUE), also known as Gauss-Markov or weighted least squares. Noise levels and correlation in the receiver channels are considered for the sake of SNR optimization. To this end, since distorted excitation profiles are sparse, $l_1$ minimization performs well in recovering the sparse distorted excitation profiles and the sparse modeling of our approach offers excellent correction of metal-induced distortions. Results: Three images reconstructed using SEMAC, SEMAC with the conventional two-step noise reduction, and the proposed image denoising for metal MRI exploiting sparsity and low rank approximation algorithm were compared. The proposed algorithm outperformed two methods and produced 119% SNR better than SEMAC and 89% SNR better than SEMAC with the conventional two-step noise reduction. Conclusion: We successfully demonstrated that the proposed, novel algorithm for SEMAC, if compared with conventional de-noising methods, substantially improves SNR and reduces artifacts.

Discriminating Domestic Soybeans from Imported Soybeans by 20 MHz Pulsed NMR (20 MHz pulsed NMR을 이용한 국내산과 수입산 콩의 판별)

  • Rho, Jeong-Hae;Lee, Sun-Min;Kim, Young-Boong;Lee, Taek-Soo
    • Korean Journal of Food Science and Technology
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    • v.35 no.4
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    • pp.653-659
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    • 2003
  • A 20 MHz pulsed NMR systems was employed to discriminate the geographical origin of soybeans and black beans (yak-kong) from Korea and foreign countries. Crude fat contents measured by soxhlet method were significantly (p<0.05) different between domestic and imported soybeans. Moisture and crude protein contents, measured by AOAC, were significantly different between domestic and imported black beans. In soybeans, values by solid fat content method and Carr-Purcell-Meiboom-Gill (CPMG) method using 20 MHz pulsed NMR showed the significant difference among soybeans from various the geographical origins. In black beans (yak-kong), NMR values measured by NMR except $T_1$ SR pulse sequence revealed the significant difference by the geographical origins. The habitat of soybeans and black beans could be identified by canonical discriminant analysis of chemical composition with $70{\sim}91.7\;%$ accuracy. Low field NMR data followed by discriminant analysis, however, granted the 100% of accuracy for classification of soybeans.

Human Friendly Recognition and Editing Support System of Korean Language (인간에게 친밀한 한글 인식 및 편집 지원시스템)

  • Sohn, Young-Sun
    • Journal of the Korean Institute of Intelligent Systems
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    • v.17 no.4
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    • pp.494-499
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    • 2007
  • In this paper we realized a system, if a user selects the area of the important parts or the arrangement parts when he reads the books or the papers, which amends, stores and readjusts the characters that are included in the selected area by outputting the characters to the word processor in sequence. If a user selects what he wishes lot with his finger, the system detects the movement of the finger by applying the hand recognition algorithm and recognizes the selected area. The system converts the distance of the width and the length of the selected area to the number of the pulse, and controls the motor to move the camera at the position. After the system scales up/down the zoom to be able to recognize the character and controls the focus to the regulated zoom closely, it controls the focus in detail to get more distinct image by using the difference of the light and darkness. We realize the recognition and editing support system of korean language that converts the obtained images to the document by applying the character recognition algorithm and arrange the important parts.

Surface-shape Processing Characteristics and Conditions during Trajectory-driven Fine-particle injection Processing (궤적 구동 미세입자 분사가공 시 표면 형상 가공 특성 및 가공 조건)

  • Lee, Hyoung-Tae;Hwang, Chul-Woong;Lee, Sea-Han;Wang, Duck Hyun
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.20 no.10
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    • pp.19-26
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    • 2021
  • In fine-particle injection processing, hard fine particles, such as silicon carbide or aluminum oxide, are injected - using high-pressure air, and a small amount of material is removed by applying an impact to the workpiece by spraying at high speeds. In this study, a two-axis stage device capable of sequence control was developed to spray various shapes, such as circles and squares, on the surface during the micro-particle jetting process to understand the surface-shape micro-particle-processing characteristics. In the experimental device, two stepper motors were used for the linear movement of the two degree-of-freedom mechanism. The signal output from the microcontroller is - converted into a signal with a current sufficient to drive the stepper motor. The stepper motor rotates precisely in synchronization with the pulse-signal input from the outside, eliminating the need for a separate rotation-angle sensor. The major factors of the processing conditions are fine particles (silicon carbide, aluminum oxide), injection pressure, nozzle diameter, feed rate, and number of injection cycles. They were identified using the ANOVA technique on the design of the experimental method. Based on this, the surface roughness of the spraying surface, surface depth of the spraying surface, and radius of the corner of the spraying surface were measured, and depending on the characteristics, the required spraying conditions were studied.

Artifacts due to Retrograde Flow in the Artery and Their Elimination in 2D TOF MR Angiography (2D TOF 자기공명 혈관조영술에서 동맥혈류의 역류로 인한 영상훼손과 이의 제거)

  • Jung, K.J.;Lee, J.K.;Kim, S.K.;Park, S.H.
    • Investigative Magnetic Resonance Imaging
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    • v.5 no.1
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    • pp.38-42
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    • 2001
  • Dark band artifacts are often observed in angiograms of arteries obtained by 2D time-of-flight (TOF) angiography with saturation of veins by presaturation RF pulses. At some arteries the arterial blood velocity varies in a triphasic pattern during a cardiac cycle. The arterial blood, that is saturated by presaturation RF pulses in the saturation band, can flow back into the imaging slice during the retrograde flow phase of the triphasic variation. When such saturated retrograde flow occurs during the acquisition of the central part of the K space, a signal void can result in base images and consequently dark band artifacts can appear in angiograms. This phenomenon is experimentally demonstrated by varying the gap between the imaging slice and the saturation band. Furthermore, a new pulse sequence is proposed to eliminate the dark band artifacts by changing the profile of the saturation band front a rectangle to a ramp.

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Usefulness of MR Imaging for Diseases of the Small Intestine: Comparison with CT

  • Ji-Hoon Kim;Hyun Kwon Ha;Min Jee Sohn;Byung Suck Shin;Young Suk Lee;Soo Yoon Chung;Pyo Nyun Kim;Moon-Gyu Lee;Yong-Ho Auh
    • Korean Journal of Radiology
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    • v.1 no.1
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    • pp.43-50
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    • 2000
  • Objective: To evaluate the usefulness of MR imaging for diseases of the small intestine, emphasizing a comparison with CT. Materials and Methods: Thirty-four patients who underwent both CT and MR imaging using FLASH 2D and HASTE sequences were analyzed. All patients had various small bowel diseases with variable association of peritoneal lesions. We compared the detectabilities of CT and MR imaging using different MR pulse sequences. The capability for analyzing the characteristics of small intestinal disease was also compared. Results: MR imaging was nearly equal to CT for detecting intraluminal or peritoneal masses, lesions in the bowel and mesentery, and small bowel obstruction, but was definitely inferior for detecting omental lesions. The most successful MR imaging sequence was HASTE for demonstrating bowel wall thickening, coronal FLASH 2D for mesenteric lesions, and axial FLASH 2D for omental lesions. MR imaging yielded greater information than CT in six of 12 inflammatory bowel diseases, while it was equal to CT in six of seven neoplasms and inferior in five of seven mesenteric ischemia. In determining the primary causes of 15 intestinal obstructions, MR imaging was correct in 11 (73%) and CT in nine (60%) patients. Conclusion: MR imaging can serve as an alternative diagnostic tool for patients with suspected inflammatory bowel disease, small intestinal neoplasm or obstruction.

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Quantitative Analysis of Brain Metabolite Spectrum Depending on the Concentration of the Contrast Media in Phantom (팬텀 내 조영제 농도에 따른 뇌 대사물질 Spectrum의 정량분석)

  • Shin, WoonJae;Gang, EunBo;Chun, SongI
    • Journal of the Korean Society of Radiology
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    • v.9 no.1
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    • pp.47-53
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    • 2015
  • Quantitative analysis of MR spectrum depending on mole concentration of the contrast media in cereberal metabolite phantom was performed. PRESS pulse sequence was used to obtain MR spectrum at 3.0T MRI system (Archieva, Philips Healthcare, Best, Netherland), and the phantom contains brain metabolites such as N-Acetyl Asparatate (NAA), Choline (Cho), Creatine (Cr) and Lactate (Lac). In this study, optimization of MRS PRESS pulse sequency depending on the concentration of contrast media (0, 0.1 and $0.3mmol/{\ell}$) was evaluated for various repetition time(TR; 1500, 1700 and 2000 ms). In control (cotrast-media-free) group, NAA and Cho signals were the highest at TR 2000 ms than at 1700 and 1500 ms. Cr had the highest peak signal at TR 1500 ms. When concentration of contrast media was $0.1mmol/{\ell}$, the metabolites were increased NAA 73%, Cho 249%, Cr 37% at TR 1700 ms compared with other TR, and also signal increased at $0.3mmol/{\ell}$, In $0.5mmol/{\ell}$ of contrast agent, cerebral metabolite peaks reduced, especially when TR 1500 ms and 2000 ms they decreased below those of control group. The ratio of metabolite peaks such as NAA/Cr and Cho/Cr decreased as the concentration of the contrast agent increased from 0.1 to $0.5mmol/{\ell}$. Authors found that the optimization of PRESS sequence for 0.3T MRS was as follows: low density of contrast agent ($0.1mmol/{\ell}$ and $0.3mmol/{\ell}$) made the highest signal intensity, while high density of contrast agent reveals the least reduction of signal intensity at 1700 ms. In conclusion, authors believe that it is helpful to reduce TR for acquiring maximum signal intensity.

A Study of Changes of Inversion Time Effect on Brain Volume of Normal Volunteers (반전 시간의 변화가 정상인의 뇌 체적에 미치는 영향에 대한 고찰)

  • Kim, Ju Ho;Kim, Seong-Hu;Shin, Hwa Seon;Kim, Ji-Eun;Na, Jae Boem;Park, Kisoo;Choi, Dae Seob
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.4
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    • pp.286-293
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    • 2013
  • Purpose : The objective of this study was to analyze the brain volume according to the brain image of healthy adults in the 20s taken with different inversion time (TI). Materials and Methods: Brain images of healthy adults in the 20 s were acquired using magnetization prepared rapid acquisition gradient echo (MPRAGE) pulse sequence with 1.5 mm thickness of pieces and four inversion times (1100 ms, 1000 ms, 900 ms, 800 ms). The acquired brain images were analyzed to measure the volume of white matter (WM), gray matter (GM), intracranial volume (ICV). The statistical difference according to brain volume and gender was analyzed for each TI. Results: The brain volume calculated using Freesurfer was WM$486.52{\pm}48.64cm^3$ and GM=$646.83{\pm}57.12cm^3$ in mean when adjusted by mean ICV=$1278.94{\pm}154.92cm^3$. Men's brain volume(WM, GM, ICV) was larger than women's brain volume. In the intrarater reliability test, all of the intraclass correlation coefficients were high (0.992 for WM, 0.988 for GM, and 0.997 for ICV). In the repeated measures analysis of variance, GM and ICV did not show a significant difference at each TI (GM p=0.143, ICV p=0.052), but WM showed a significant (p=0.001). In the linear structure relation analysis, all of the Pearson correlation coefficients were high. Conclusion: WM, GM, and ICV indicated high reliability and solid linear structure relations, but WM showed significant differences at each TI. The brain volume of healthy adults in the 20s could be used in comparison with that of patients for reference purposes and to predict the structural change of brain. It would be needed to conduct additional studies to examine the contract, SNR, and lesion detection ability according to variable TI.