• Title/Summary/Keyword: Pulse interval

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A Study on 8kbps PC-MPC by Using Position Compensation Method of Multi-Pulse (멀티펄스의 위치보정 방법을 이용한 8kbps PC-MPC에 관한 연구)

  • Lee, See-Woo
    • Journal of Digital Convergence
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    • v.11 no.5
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    • pp.285-290
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    • 2013
  • In a MPC coding using excitation source of voiced and unvoiced, it would be a distortion of speech waveform. This is caused by normalization of synthesis speech waveform of voiced in the process of restoration the multi-pulses of representation section. To solve this problem, this paper present a method of position compensation(PC-MPC) in a multi-pulses each pitch interval in order to reduce distortion of speech waveform. I was confirmed that the method can be synthesized close to the original speech waveform. And I evaluate the MPC and PC-MPC using multi-pulses position compensation method. As a result, $SNR_{seg}$ of PC-MPC was improved 0.4dB for female voice and 0.5dB for male voice respectively. Compared to the MPC, $SNR_{seg}$ of PC-MPC has been improved that I was able to control the distortion of the speech waveform finally. And so, I expect to be able to this method for cellular phone and smart phone using excitation source of low bit rate.

Multiplexed Hard-Polymer-Clad Fiber Temperature Sensor Using An Optical Time-Domain Reflectometer

  • Lee, Jung-Ryul;Kim, Hyeng-Cheol
    • International Journal of Aeronautical and Space Sciences
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    • v.17 no.1
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    • pp.37-44
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    • 2016
  • Optical fiber temperature sensing systems have incomparable advantages over traditional electrical-cable-based monitoring systems. However, the fiber optic interrogators and sensors have often been rejected as a temperature monitoring technology in real-world industrial applications because of high cost and over-specification. This study proposes a multiplexed fiber optic temperature monitoring sensor system using an economical Optical Time-Domain Reflectometer (OTDR) and Hard-Polymer-Clad Fiber (HPCF). HPCF is a special optical fiber in which a hard polymer cladding made of fluoroacrylate acts as a protective coating for an inner silica core. An OTDR is an optical loss measurement system that provides optical loss and event distance measurement in real time. A temperature sensor array with the five sensor nodes at 10-m interval was economically and quickly made by locally stripping HPCF clad through photo-thermal and photo-chemical processes using a continuous/pulse hybrid-mode laser. The exposed cores created backscattering signals in the OTDR attenuation trace. It was demonstrated that the backscattering peaks were independently sensitive to temperature variation. Since the 1.5-mm-long exposed core showed a 5-m-wide backscattering peak, the OTDR with a spatial resolution of 40 mm allows for making a sensor node at every 5 m for independent multiplexing. The performance of the sensor node included an operating range of up to $120^{\circ}C$, a resolution of $0.59^{\circ}C$, and a temperature sensitivity of $-0.00967dB/^{\circ}C$. Temperature monitoring errors in the environment tests stood at $0.76^{\circ}C$ and $0.36^{\circ}C$ under the temperature variation of the unstrapped fiber region and the vibration of the sensor node. The small sensitivities to the environment and the economic feasibility of the highly multiplexed HPCF temperature monitoring sensor system will be important advantages for use as system-integrated temperature sensors.

Optimization of GTAW Parameters for Horizontal Welding of a STS316L Pipe (STS316L 강관의 수평자세 용접을 위한 GTAW 용접조건의 최적화)

  • Lee, Hyoung-Keun;Bang, Kyoung-Sik
    • Journal of Welding and Joining
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    • v.33 no.5
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    • pp.47-52
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    • 2015
  • In this study, it was tried to analyze the effects of welding parameters on the weld penetration and aspect ratio when a STS316L pipe was welded in a horizontal position by GTAW. Experiments were systematically designed using a L18 orthogonal array, and the effects of welding parameters were statistically analyzed by ANOVA(Analysis of Variance). The shielding gas type has the largest effect on both the penetration and aspect ratio. The welding current type and shielding gas flow rate have a little effect on the penetration, whereas the electrode tip angle has a little effect on the aspect ratio. When welded at a selected welding condition, which is composed of He shielding gas, pulse current of 300/45 A, electrode tip angle of 90o, and shielding gas flow rate of 30 l/min, the estimated interval at least 95 % confidence was $1.99{\pm}0.18mm$ for the penetration and $0.31{\pm}0.04$ for the aspect ratio. From the confirmation experiments, the average penetration and aspect ratio were well agreed with the estimation as 1.96 mm and 0.30, respectively. Additionally, the effects of the welding speed and welding current on the penetration and aspect ratio were experimented and analyzed by linear regression. The penetration was linearly increased with the decrease of the welding speed and with the increase of the welding current, but the aspect ratio showed a tendency to a little decrease with the increase of both the welding speed and current.

An E-mail survey for expanding the basic benefit package of Korean medicine in Korean national health insurance (한의 의료행위 급여 항목 확대 방안 모색을 위한 전자우편 설문조사)

  • Kim, Mikyung;Kim, Ga-hee;Han, Chang-ho
    • The Journal of Korean Medicine
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    • v.39 no.3
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    • pp.51-60
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    • 2018
  • Objectives: This study aimed to investigate the opinions of Korean medical doctors on how to elucidate possible remedial measures for expanding the health insurance benefits coverage item of Korean medicine (KM). Methods: An online survey was conducted to all members who had registered e-mail address in the association of Korean medicine from 1 to 17 November, 2016. Statistical analysis was performed and odds ratio with 95% confidence interval were calculated by each subgroup. Results: A total of 743 members answered the questions and the response rate was 4.1%. The priorities for expanding health insurance benefits were as follows: thermographic imaging, Sasang constitution typing test, and pulse wave among examinations; pharamacopuncture, embedding acupuncture, and acupotomy among procedures; Chuna manual therapy, manual therapy for meridian muscle, and Daoyin exercise therapy among manual therapies; low-frequency electrical therapy, traction, paraffin bath, and light therapy among physical therapies; and aromatherapy, enema therapy, and color therapy among activities of KM. Conclusions: It should be covered by the national health insurance (NHI) of KM that thermographic imaging, pharmacoacupuncture, Chuna manual therapy, low-frequency electrical therapy, aromatherapy as a top priority. We also suggest that basic medical tests, such as blood, urine, or imaging, should be included in the coverage of the NHI of KM. It is necessary to review the expertise and public opinions about the plans and priorities for the conversion of the desired medical services to be covered by the NHI.

A Simulation Study of a Chopping System for Extracting a Pulsed Beam from a Cyclotron

  • Kim, Jae-Hong;Hong, Seong-Gwang;Kim, Mi-Jeong;Kim, Seong-Jun;Kim, Myeong-Jin;Kim, Do-Gyun;Yun, Jong-Cheol;Kim, Jong-Won
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.537-537
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    • 2013
  • Cyclotron-accelerated ion beams are used for various researches, such as nuclear physics, nuclear chemistry, biotechnology, and material sciences including radio-isotope production. Recently considerable applications are asked to the cyclotron development undertaken to meet user requirements of various ions'energies, intensities, and their pulsed beams. For instance, a cocktail beam acceleration technique rapidly changing the ion species and energies was developed to irradiating integrated circuit chips. Also a chopping system in a cyclotron injection line is considered for producing a pulsed ion beam with a relatively long period compared with that generated by the resonance frequency. For the research in neutron time-of-flight measurement, a single-pulsed beam with a repetition interval of the order of mili-seconds or longer is necessary to have a good resolution and to remove background events. In this paper a feasibility of pulsed beam with an external ion source is simulated by adopting a combination system of a chopper accompanying with a bunching stage in the injection line and an additional chopper after the exit of the cyclotron in order to produce beam pulses with a range of $1{\mu}s{\sim}1ms$ periods from a resonance RF cycle. The pulseperiod will be adjusted by chopping the number of beam bunches from the injected pulses in the injection line. However, the longer pulses will have reduced number of beam pulses and sacrificed beam currents. Because the beam users need an intense single pulsed beam, a careful tuning of the acceleration phase and a high-intense external ion source are necessary to achieve an intense single-pulsed beam from the cyclotron. It is essential to strictly match the acceleration phase of injected beams in the central region of the cyclotron to improve its efficiency. An effect of space charge at each pulse from the ion source will be also considered.

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Inhibitory Modulation of 5-Hydroxytryptamine on Corticostriatal Synaptic Transmission in Rat Brain Slice

  • Choi, Se-Joon;Chung, Won-Soon;Kim, Ki-Jung;Sung, Ki-Wug
    • The Korean Journal of Physiology and Pharmacology
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    • v.7 no.6
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    • pp.295-301
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    • 2003
  • Striatum plays a crucial role in the movement control and habitual learning. It receives an information from wide area of cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT) input from raphe nuclei. In the present study, the effects of 5-HT to modulate synaptic transmission were studied in the rat corticostriatal brain slice using in vitro extracellular recording technique. Synaptic responses were evoked by stimulation of cortical glutamatergic inputs on the corpus callosum and recorded in the dorsal striatum. 5-HT reversibly inhibited coticostriatal glutamatergic synaptic transmission in a dose-dependent fashion (5, 10, 50, and $10{\mu}M$), maximally reducing in the corticostriatal population spike (PS) amplitude to $40.1{\pm}5.0$% at a concentration of $50{\mu}M$ 5-HT. PSs mediated by non-NMDA glutamate receptors, which were isolated by bath application of the NMDA receptor antagonist, d,l-2-amino-5-phospohonovaleric acid (AP-V), were decreased by application of $50{\mu}M$ 5-HT. However, PSs mediated by NMDA receptors, that were activated by application of zero $Mg^{2+}$ aCSF, were not significantly affected by $50{\mu}M$ 5-HT. To test whether the corticostriatal synaptic inhibitions by 5-HT might involve a change in the probability of neurotransmitter release from presynaptic nerve terminals, we measured the paired-pulse ratio (PPR) evoked by 2 identical pulses (50 ms interpulse interval), and found that PPR was increased ($33.4{\pm}5.2$%) by 5-HT, reflecting decreased neurotransmitter releasing probability. These results suggest that 5-HT may decrease neurotransmitter release probability of glutamatergic corticostriatal synapse and may be able to selectively decrease non-NMDA glutamate receptor-mediated synaptic transmission.

The Therapeutic Effects of a Pulsed Nd:YAG Laser on Oral Lesions (구강병소에 대한 펄스형 Nd: YAG 레이저의 치료효과)

  • 신금백
    • Journal of Oral Medicine and Pain
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    • v.22 no.2
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    • pp.309-325
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    • 1997
  • In order to set the lasing variables and evaluate, clinically, the therapeutic effects of a pulsed Nd:YAG laser on oral lesion, the author applied the laser energy from a fiberoptic delivered, free running, pulsed Nd:YAG laser (wavelength 1064nm, Pulse duration 120$\mu$sec, fiber diameter 200$\mu$m/320$\mu$m) to 22 cases of oral soft tissue lesions and 6 cases of oral hard tissue lesions. The obtained results were as follows : 1. The effective excision with contact mode and the effective hemostasis of accompanied bleeding with noncontact mode were occurred by lasing on oral soft tissue lesions with fiber diameter of 320$\mu$m under the variables of 2.0~4.0W and 20~50Hz which were controlled into high power/low pulses for excision, low power/high pulses for hemostasis, low power in granulation tissue and high power in fibrous tissue according to therapeutic goals and tissue conditions. 2. About 50% of decreasing effect on hypersensitivity was occurred by lasing with non-contact and contact mode on cervical abrasion which caused dentinal hypersensitivity with fiber diameter of 320$\mu$m under the variables of 0.7 - 1.0W and 10Hz which were applied 2~3 times with 1 week interval. 3. The effective sterilization of infected root canal and lesion of periapical abscess was occurred by lasing with contact and spiral modes on wall of root canal and periapical abscess with fiber diameter of 200$\mu$m of which the tip was placed about 1mm shorter than root canal length under the variables of 1.OW and 10Hz.

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The Effects of Local Anesthetic Agent and Epinephrine on Blood Flow of Femoral Artery in Rabbit (가토에서 국소 마취제와 Epinephrine이 대퇴동맥이 혈류에 미치는 영향)

  • Oh, Soo-Won;Koo, Gil-Hoi;Lee, Choon-Hi
    • The Korean Journal of Pain
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    • v.9 no.1
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    • pp.46-56
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    • 1996
  • Many surgeons and anesthesiologists prefer using vasoconstrictor mixed with local anesthetic agent to reduce the incidence of side effects and prolong the duration of analgesia because most local anesthetic agents, except cocaine, were believed to possess vasodilating effect. However, some investigators recently reported vasoconstricting effect of local anesthetic agents. There is still controversy on the vasoactive effect of local anesthetic agents. So this study is aimed to clarify the vasoactive effect of local anesthetics in the animal model resembling clinical settings. Rabbits were anesthesized with ketamine and haloghane, and respirations were controlled with Harvard animal ventilator. Lidocaine (0.5%, 1.0%, 1.5%) and bupivacaine (0.125%, 0.25% and 0.5%) with or without 1:100,000 epinephrine were subdermaly injected on the femoral bupivacaine of the femoral artery were measured with Doppler flow meter in vivo. The mean arterial pressure, pulse rate, arterial blood gases, pH and level of serum electrolytes were measured at every 2 minute interval for 30 minutes. Results were as follows: 1) There was no significant vasoconstriction with 0.5% lidocaine and 0.125% bupivacaine. 2) Statistically significant (p<0.05) vasodilations were observed with lidocaine (1.0~2.0%) and bupivacaine (0.25~0.5%). 3) There were no changes on the duration of vasodilation induced by local anesthetic agents of various concentrations. 4) Onset of vasodilation induced by local anesthetic agents of high concentration were faster than that of lower concentrations. 5) In the mixed injection group of epinephrine and local anesthetic agent, the vasoconstriction induced by epinephrine was completely reversed by local anesthetics, approximately 5 minutes later. In conclusion, local anesthetic agents at dose exceeding 1.0% lidocaine and 0.25% bupivacaine increase local blood flow significantly in animal study in vivo which is applicable in human clinical settings. The increase blood flow may be due to dilatation of blood vessel. Further study on the analysis of association between amount of absorbed local anesthetics in blood vessels and dilatation of blood vessels is needed.

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Response of $I_{Kr}$ and hERG Currents to the Antipsychotics Tiapride and Sulpiride

  • Jo, Su-Hyun;Lee, So-Young
    • The Korean Journal of Physiology and Pharmacology
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    • v.14 no.5
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    • pp.305-310
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    • 2010
  • The human $ether$-$a$-$go$-$go$-related gene ($hERG$) channel is important for repolarization in human myocardium and is a common target for drugs that prolong the QT interval. We studied the effects of two antipsychotics, tiapride and sulpiride, on hERG channels expressed in $Xenopus$ oocytes and also on delayed rectifier $K^+$ currents in guinea pig cardiomyocytes. Neither the amplitude of the hERG outward currents measured at the end of the voltage pulse, nor the amplitude of hERG tail currents, showed any concentration-dependent changes with either tiapride or sulpiride ($3{\sim}300{\mu}M$). However, our findings did show that tiapride increased the potential for half-maximal activation ($V_{1/2}$) of HERG at $10{\sim}300{\mu}M$, whereas sulpiride increased the maximum conductance ($G_{max}$) at 3, 10 and $100{\mu}M$. In guinea pig ventricular myocytes, bath applications of 100 and $500{\mu}M$ tiapride at $36^{\circ}C$ blocked rapidly activating delayed rectifier $K^+$ current ($I_{Kr}$) by 40.3% and 70.0%, respectively. Also, sulpiride at 100 and $500{\mu}M$ blocked $I_{Kr}$ by 38.9% and 76.5%, respectively. However, neither tiapride nor sulpiride significantly affected the slowly activating delayed rectifier $K^+$ current ($I_{Ks}$) at the same concentrations. Our findings suggest that the concentrations of the antipsychotics required to evoke a 50% inhibition of IKr are well above the reported therapeutic plasma concentrations of free and total compound.

Critical earthquake input energy to connected building structures using impulse input

  • Fukumoto, Yoshiyuki;Takewaki, Izuru
    • Earthquakes and Structures
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    • v.9 no.6
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    • pp.1133-1152
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    • 2015
  • A frequency-domain method is developed for evaluating the earthquake input energy to two building structures connected by viscous dampers. It is shown that the earthquake input energies to respective building structures and viscous connecting dampers can be defined as works done by the boundary forces between the subsystems on their corresponding displacements. It is demonstrated that the proposed energy transfer function is very useful for clear understanding of dependence of energy consumption ratios in respective buildings and connecting viscous dampers on their properties. It can be shown that the area of the energy transfer function for the total system is constant regardless of natural period and damping ratio because the constant Fourier amplitude of the input acceleration, relating directly the area of the energy transfer function to the input energy, indicates the Dirac delta function and only an initial velocity (kinetic energy) is given in this case. Owing to the constant area property of the energy transfer functions, the total input energy to the overall system including both buildings and connecting viscous dampers is approximately constant regardless of the quantity of connecting viscous dampers. This property leads to an advantageous feature that, if the energy consumption in the connecting viscous dampers increases, the input energies to the buildings can be reduced drastically. For the worst case analysis, critical excitation problems with respect to the impulse interval for double impulse (simplification of pulse-type impulsive ground motion) and multiple impulses (simplification of long-duration ground motion) are considered and their solutions are provided.