• Journal of Magnetics
• /
• 제19권3호
• /
• pp.255-260
• /
• 2014

A portable clip-type pulsimeter equipped with a magnetic sensing Hall device has been developed to raise the accuracy of oriental disease diagnosis and therapy by convergence of magnetism and oriental medicine. To improve accuracy and reliability of conventional pulsimeter due to subjective analysis of the pulse wave and measuring position dependency of the arterial pulse sensor, the fuzzy algorithm was applied to analyze the strong- and weak-pulse wave symptom. Optimal time for electronic acupuncture was calculated using fuzzy rules and interference were drawn from objective data in view of pre-treatment. Moreover, the electrical characteristics of the pain parts that respond to acupuncture point were applied in view of post-treatment to propose the scientific pulse wave algorithm and simulation experiment.

• 센서학회지
• /
• 제27권4호
• /
• pp.259-263
• /
• 2018

A radial artery pulse wave is measured while pressing an artery with constant force. However, pulse waveform measurements vary depending on pressing force and direction. Accurate pulse waveform measurements are important for analysis. Thus, it is necessary to define the measurement range of the permissible force and direction from which a correct pulse waveform is derived. In this study, pulse waves were generated by a pulse wave generator for accurate control. The pulse waves generated for different angles and pressing forces were analyzed. The augmentation index (AIx), which is the most commonly used index for evaluating vascular stiffness, was analyzed. The AIx was measured within ${\pm}6^{\circ}$ of the vessel direction and within ${\pm}8^{\circ}$ perpendicular to the vessel direction with a force that was 25% or more of the pressing force at which the maximum pressure wave was generated. We identified the applicable pressing force and angle range by analyzing the effect of pressing angle on the pulse wave. The AIx analysis performed using the pulse wave measurement device is reliable and reproducible.

• 대한한의진단학회지
• /
• 제11권1호
• /
• pp.48-60
• /
• 2007

Palpation of the pulse has been used in Korean traditional medicine since ancient times to assess physical health. Pulse wave contour may be obtained by measuring arterial pressure or blood volume change of skin. The latter is called as Photoplethysmography(PPG) or digital volume pulse(DVP). The PPG signal is measured by a device comprising an infrared light sourece and a photodetector. Although less widely used, this technique deserves further consideration because of its simplicity and ease of use. The contour of the PPG is formed as a result of a complex interaction between the left ventricle and the systemic circulation. It usually exhibits an early systolic peak and an early diastolic peak. the first peak is formed mainly by pressure trasmitted along a direct path from the left ventricle to the finger. The second peak is formed in part by pressure transmitted along the aorta and large arteries to sites of impedance mismatch in the lower body. The contour of the PPG is sensitive to changes in arterial tone and is influenced by ageing and large artery stiffness. Measurements taken directly from the PPG or from its second derivative can be used to assess these properties. In some mathematical approaches, the extraction of periodic components using frequency analysis was tried to analysis of the PPG. But we don't understand yet what kind of factor in the cardiovascular system or human body is related with the respective specific Fourier components of PPG. This review describes the background to measurement principles, representative contour, contour analysis and frequency domain analysis of PPG, and current and future.

• 한국자기학회지
• /
• 제22권4호
• /
• pp.136-141
• /
• 2012

본 연구에서는 집게형 맥진기와 심전도계를 이용하여 전기적인 심전도 파형과 요골동맥파형을 동시 측정하여 얻은 맥파전달속도를 분석하였다. 두 신호의 동시 측정에 의한 맥파전달속도는 평균 6 m/s의 값을 보여 주었으며, ECG 파형과 홀소자 맥진파형으로 동시 측정한 방법은 기존 방법들 보다 정확하게 맥파전달속도를 측정할 수 있는 새로운 방법임을 입증하였다. 따라서 이결과는 한방의료기기인 맥진기에서 측정된 데이터를 임상적으로 활용할 수 있음을 보인다.

• 대한한의진단학회지
• /
• 제16권3호
• /
• pp.33-40
• /
• 2012

Objectives: Existing cardiovascular simulators are used to evaluate artificial organs such as artificial hearts, prosthetic valves, and artificial blood vessels, and pulses are typically triggered using artificial hearts. However, the forms of pulse waves vary according to the location of arteries, and for precise assessment of artificial blood vessels, the development of simulators that generate diverse pressure pulse waves is necessary. This study developed a novel cardiovascular simulator that generates different forms of pulse waves. Methods: This simulator consists of a stepping motor, a slider-crank mechanism that transforms the rotation movement of a motor into the straight-line motion of a piston, a piston that generates pulsatile flows, a water tank that supplies fluids, an elastic tube made of silicon, and a device that adjusts the terminal resistance of fluids. Results & Conclusion: This study examined motor rotation and its operation under conditions similar to the physiological conditions of the heart. The simulator developed in this study produced diverse forms of waves, and the generated pressure waves well satisfied physiological conditions.

• 대한한의학회지
• /
• 제30권3호
• /
• pp.98-105
• /
• 2009

Objective: Increased aortic and carotid arterial augmentation index (AI) is associated with the risk of cardiovascular disease. The most widely used approach for determining central arterial AI is by calculating the aortic pressure waveform from radial arterial waveforms using a transfer function. But how the change of waveform by applied pressure and the pattern of the change rely on subject's characteristics has not been recognized. In this study, we use a new method for measuring radial waveform and observe the change of waveform and the deviation of radial AI in the same position by applied pressure. Method: Forty-six non-patient volunteers (31 men and 15 women, age range 21-58 years) were enrolled for this study. Informed consent in a form approved by the institutional review board was obtained in all subjects. Blood pressure was measured on the left upper arm using an oscillometric method, radial pressure waves were recorded with the use of an improved automated tonometry device. DMP-3000(DAEYOMEDI Co., Ltd. Ansan, Korea) has robotics mechanism to scan and trace automatically. For each subject, we performed the procedure 5 times for each applied pressure level. We could thus obtain 5 different radial pulse waveforms for the same person's same position at different applied pressures. All these processes were repeated twice for test reproducibility. Result: Aortic AI, peripheral AI and radial AI were higher in women than in men (P<0.01), radial AI strongly correlated with aortic AI, and radial AI was consistently approximately 39% higher than aortic AI. Relationship between representative radial AI of DMP-3000 and peripheral AI of SphygmoCor had strongly correlation. And there were three patterns in change of pulse waveform. Conclusion: In this study, it is revealed the new device was sufficient to measure how radial AI and radial waveform from the same person at the same time change under applied pressure and it had inverse-proportion to applied pressure.

• 대한한의진단학회지
• /
• 제12권2호
• /
• pp.1-7
• /
• 2008

Objectives: The basis research of aged people's healthcare technology is very important, because our nation goes into an aged society rapidly. Especially in traditional medicine, pulse shapes of aged people were supposed to weak and empty pulse until now, but any objective measurement and compare research do not taken. Methods and Results: Therefore in this study we design observation study to find characteristic of pulse between younger group (age $20{\sim}30$) and elder group (age $43{\sim}80$) in Busan area. We used 3-dimensional pulse analyzer '3-D MAC' (Daeyomedi Co., Ltd.). And major parameters for comparison are 1) pulse height (h1), 2) applied pressure, 3) pulse power (energy), 4) high pressure duration (w) and 5) R-AI. Conclusions: According to analysis result, elder people's pulse has more large value in pulse height, applied pressure and pulse power than younger's that. It reveals that elder people in modernized lifestyle has Yang symptoms as well Yin symptoms. Consequently we need new method to care elder people's health, and this means more important direction than old text book. From now on verification research with objective diagnosis device like 3-D MAC, must be activated to build of evidence in traditional medicine. Cause traditional medicine's spirit of care and prevention is suitable to care elder people's cardiac and cerebral vascular disease those are have close relation with elder people.

• 한국자기학회:학술대회 개요집
• /
• 한국자기학회 2005년도 하계학술연구발표회 논문개요집
• /
• pp.128-129
• /
• 2005

• 대한약침학회지
• /
• 제19권3호
• /
• pp.197-206
• /
• 2016

Introduction: This study aims to investigate the effects of acupuncture stimulation on the radial artery's pressure pulse wave, along with various hemodynamic parameters, and to explore the possible underlying mechanism of pulse diagnosis in healthy participants in their twenties. Methods and analysis: This study is a prospective, single-arm, exploratory clinical study. A total of 25 healthy participants, without regard to gender, in their twenties will be recruited by physicians. Written informed consent will be obtained from all participants. The participants will receive acupuncture once at ST36 on both sides. The radial arterial pulse waves will be measured on the left arm of the subjects by using an applicable pulse tonometric device (KIOM-PAS). On the right arm (appearing twice), electrocardiogram (ECG), photoplethysmogram (PPG), respiration and cardiac output (CO) signals, will be measured using a physiological data acquisition system (Biopac module), while the velocity of blood flow, and the diameter and the depth of the blood vessel will be measured using an ultrasonogram machine on the right arm (appearing twice). All measurements will be conducted before, during, and after acupuncture. The primary outcome will be the spectral energy at high frequencies above 10 Hz ($SE_{10-30Hz}$) calculated from the KIOM-PAS device signal. Secondary outcomes will be various variables obtained from the KIOM-PAS device, ECG, PPG, impedance cardiography modules, and an ultrasonogram machine. Discussion: The results of this trial will provide information regarding the physiological and the hemodynamic mechanisms underlying acupuncture stimulation and clinical evidence for the influence of acupuncture on the pressure pulse wave in the radial artery. Ethics and dissemination: This study was approved by the Institutional Review Board (IRB) of Kyung Hee University's Oriental Medical Center, Seoul, Korea (KOMCIRB-150818-HR-030). The study findings will be published in peer-reviewed journals and presented at national and international conferences. Trial registration number: This trial was registered with the Clinical Research Information Service (CRIS) at the Korea National Institute of Health (NIH), Republic of Korea (KCT0001663), which is a registry in the World Health Organization's (WHO's) Registry Network.

• Journal of Magnetics
• /
• 제21권2호
• /
• pp.266-272
• /
• 2016

Transcranial magnetic stimulation devices has been used mainly for diagnostic purposes by measuring the functions of the nervous system rather than for treatment purposes, and has a problem of considerable energy fluctuations per repeated pulse. The majority of strokes are caused by ischemia and result in brain tissue damage, leading to problems of the central nervous system including hemiparesis, dysfunction of language and consciousness, and dysfunction of perception. Control is difficult and the size is large due to the difficulty of digitalizing the energy stored in a capacitor, and there are many heavy devices. In addition, there are many constraints when it is used for a range of purposes such as head and neck diagnosis, treatment and rehabilitation of nerve palsy, muscle strengthening, treatment of urinary incontinence etc. Output stabilization and minimization of the energy variation rate are required as the level of the transcranial magnetic stimulation device is dramatically improved and the demand for therapeutic purposes increases. This study developed a compact, low cost transcranial magnetic stimulation device with minimal energy variation of a high repeated pulse and output stabilization using a real time capacitor charge discharge voltage. Ischemia was induced in male SD rats by closing off the common carotid artery for 5 minutes, after which the blood was re-perfused. In the cerebrum, the number of PARP reactive cells after 24 hours significantly decreased (p < 0.05) in the TMS group compared to the GI group. As a result, TMS showed the greatest effect on necrosis-related PARP immuno-reactive cells 24 hours after ischemia, indicating necrosis inhibition, blocking of neural cell death, and protection of neural cells.