• Title/Summary/Keyword: PubMed

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Integration of the PubAnnotation ecosystem in the development of a web-based search tool for alternative methods

  • Neves, Mariana
    • Genomics & Informatics
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    • v.18 no.2
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    • pp.18.1-18.5
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    • 2020
  • Finding publications that propose alternative methods to animal experiments is an important but time-consuming task since researchers need to perform various queries to literature databases and screen many articles to assess two important aspects: the relevance of the article to the research question, and whether the article's proposed approach qualifies to being an alternative method. We are currently developing a Web application to support finding alternative methods to animal experiments. The current (under development) version of the application utilizes external tools and resources for document processing, and relies on the PubAnnotation ecosystem for annotation querying, annotation storage, dictionary-based tagging of cell lines, and annotation visualization. Currently, our two PubAnnotation repositories for discourse elements contain annotations for more than 110k PubMed documents. Further, we created an annotator for cell lines that contain more than 196k terms from Cellosaurus. Finally, we are experimenting with TextAE for annotation visualization and for user feedback.

Review on randomized controlled trials of acupuncture for postmenopausal symptoms in the search site, Pub Med. - focusing on hot flush (Pub Med 검색을 통한 폐경기 증상의 침구 임상시험에 대한 고찰 - 안면홍조를 중심으로)

  • Kim, Ro-Sa;Lee, Jin-Moo;Cho, Jung-Hoon;Jang, Jun-Bock;Lee, Kyung-Sub;Lee, Chang-Hoon
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.4
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    • pp.148-159
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    • 2007
  • Purpose: Vasomotor symptoms including hot flash are very common to postmenopausal women. Estrogen therapy was regarded as the best option for relieving menopausal symptoms until 2002, when the Women#s Health Initiative(WHI) reported the side effect of the therapy. Consequently, studies on the complementary and alternative medical herbs and therapy for the management of menopausal symptoms have followed. And so we have reviewed some international clinical studies about the management of postmenopausal symptoms with acupuncture therapy. Methods: "Menopause and acupuncture" was designated as a key word in the search site. Pub Med, and nine papers dealing with hot flash among the relevant RCTs were selected, and then, the effect of acupuncture on hot flash and the way the researches had been done was examined. Results : The intensity of hot flash reduced significantly and the frequency of hot flash was inclined to reduce, but not significantly, compared to the controlled group. Conclusion: Each clinical test has its limitations in point of the number of the required samples. However, it still shows the possibility that acupuncture itself will be effective enough to reduce the intensity of hot flash to a certain degree. It is believed that extensive clinical tests on the effect of acupuncture on hot flash will need to be done hereafter. And when the tests are carried out, it is required to exclude placebo effect, do blind test, and carefully select and control the methods.

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Exploring Medical Doctors' Medical Information Seeking Behaviors (의사들의 의료정보추구행태에 관한 탐구)

  • Kim, Na-Won;Park, Ji-Hong
    • Journal of the Korean Society for information Management
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    • v.26 no.3
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    • pp.435-449
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    • 2009
  • Rapid change in information use environments that corresponds with the development of new technologies requires a new perspective in examining information source uses and information services. As understanding information seeking behaviors is an essential element for improving information services, the changing information seeking behaviors should be examined in a timely manner. While several prior studies focus on this topic, few studies deal with medical doctors' information seeking behaviors especially focusing on information seeking in both medical practices and research. Thus, this study aims to explore the information seeking behaviors of medical doctors who are both medical practitioners and researchers. Data were obtained by open-ended and semi-structured in-depth interviews during one month from April to May, 2009. The interview-question topics ranged from research contexts, medical-practice-related information seeking behaviors, favorable information sources, and information search process and satisfaction. Findings include that, for research purpose, digital journal articles accessed through the PubMed were more favorable sources while, for practice purpose, printed textbooks were preferred. Overall, the most-frequently-used sources were PubMed and articles because medical doctors regard the reliability and authority very highly.

Implementing Biological Network Analysis System through Oriental Medical Literature Analysis (한의학 분야 문헌 분석을 통한 생물학적 네트워크 분석시스템 개발)

  • Yu, Seok Jong;Cho, Yongseong;Lee, Junehawk;Seo, Dongmin;Yea, Sang-Jun;Kim, Chul
    • The Journal of the Korea Contents Association
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    • v.15 no.10
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    • pp.616-625
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    • 2015
  • Currently, oriental medicine research is focused with modern research technology and validate it's various biochemical effect by combining with molecular biology technology. But there are few searching system for finding biochemical mechanism which is related to major compounds in oriental medicine. In this research, we aimed developing korean herb database based on text-mining system by analyzing PubMed data. We have developed prototype system for searching chemical, gene and biological relation in oriental medicine. It is characterized by modern oriental medicine research trend with major chemical, gene and protein information. Analysis results can be searched on the prototype system with visualization of the biological interactions.