• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1996.04a
• /
• pp.241-241
• /
• 1996

새로운 항암성 백금(II)착제 SA: ([Pt( trans-1-dach) (DPPE)]ㆍ2NO$_3$, SB: [Pt (cis-dach)(DPPP)]ㆍ2NO$_3$, SC: [Pt(cis-dach)(DPPE)]ㆍ2NO$_3$에 대한 일반 약리작용이 rat, mouse 및 rabbit에서 검토되었다. Rota-rod test에 의한 운동 협조능, thiopental-Na의 수면 작용, 현수에 의한 근이완 작용, 정상체온, strychnine 유발 경련, 담즙분비, 수정관, 자궁각, 피부혈관 투과성, 국소마취, 용혈 및 심전도에 대하여 SA, SB. SC는 별다른 영향을 미치지 않았단. 적출회장과 십이지장에 대하여 SA는 수축반응을 나타내었으나 SB와 SC는 하등의 영향이 없었으며 혈액 응고에 대하여 SA는 prothrombine time을 단축시켰으나 SB, SC는 별다른 영향이 없었고 호흡에 대해서는 SA, SB, SC 다같이 호흡수를 억제하였다. 적출심장 기능에 대하여 SA, SB, SC 다같이 고농도에서 억제적으로 작용하였다.

• Proceedings of the KIEE Conference
• /
• 1994.11a
• /
• pp.196-198
• /
• 1994

The dielectric and electrical properties of $Pb(Mg_{1/3}Nb_{2\3})O_3-PbTiO_3-BaTiO_3$ have been investigated. Perovskite crystalline phase of the specimens are confirmed by XRD at $1270^{\circ}C$. The curie temperature is around $40^{\circ}C$ with the amount of $BaTiO_3$ and $PbTiO_3$. Every specimens shows the slim loop hysteresis curves which is electrostrictive characteristic. The strain vs. applied voltage characteristics exhibits nonlinear relationship, and the specimen of 0.85PMN-0.125PT-0.025BT shows the largest strain.

• Journal of the Korean Chemical Society
• /
• v.43 no.4
• /
• pp.407-411
• /
• 1999

Studies have been carried out on the fabrication of PPy/GC and PPy/Pt electrode modified with polypyrrole film and determination of Cr(VI) by using 3-electrode system with modified electrodes. Modified electrodes were able to easily fabricated by cyclic voltammetry scanned from +1.0V to -1.0V(vs. Ag/AgCl) at 50 mV/sec. Film thickness could be controlled at same condition by the number of cycling up to 26 times. Reduction behaviour of Cr(VI) at PPy/GC electrode could be seen at wide potential ranges from +0.6V to -0.5V(vs. Ag/AgCl), and maximum reduction peak potential of the ion was observed at -0.25V(vs.Ag/AgCl). Calibration graph at its potential was linear from 0.1 ppm to 80.O ppm. Slope factor and relative coefficient were 1.75 mA/ppm and 0.998, respectively. Reduction behaviour of Cr(VI) at PPy/Pt electrode was similar to PPy/GC electrode, Calibration graph was linear from l.0 ppm to 60.0 ppm. Slope factor and relative coefficient were 0.5mA/ppm and 0.923, respectively. But PPy/GC modified electrode had about 3 times higher sensitivity than PPy/Pt modified electrode. Reduction behaviour of Cu(II), As(IlI), Pb(II), and Cd(II) couldn't be seen at PPy/GC electrode,Its metals had not lnterfered with Cr (VI) determination.

• Applied Chemistry for Engineering
• /
• v.16 no.2
• /
• pp.206-211
• /
• 2005

Mediated electrochemical oxidation (MEO) of polyethylene glycols (PEGs) of molecular weight of 1000, 4000 and 20000, was carried out on both platinum (Pt) and titanium-iridium electrodes in 8.0 M nitric acid solution containing 0.5 M Fe(II) and Co(II) ion. The electrochemical parameters such as current densities, kinds of electrode, electrolyte concentration and removal efficiency were investigated in both Fe(III)/Fe(II) and Co(III)/Co(II) redox systems. The PEGs was decomposed into carbon dioxide by MEO in Fe(III)/Fe(II) and Co(III)/Co(II) redox system during 180 min and 210 min at the current density of $0.67A/cm^2$ on the Pt electrode. Removal efficiency of PEGs by MEO was better in Co(III)/Co(II) redox system than Fe(III)/Fe(II) redox system, indicating mediated electrochemical removal efficiency was 100%.

• Bulletin of the Korean Chemical Society
• /
• v.30 no.12
• /
• pp.3069-3072
• /
• 2009

• Archives of Pharmacal Research
• /
• v.15 no.4
• /
• pp.336-342
• /
• 1992

Ten [$Pd^{II}$(dicarboxylato)(1, 2-diaminocyclohexane)] complexes were prepared after the antitumor-active Pt(II)1, 2-diaminocyclohexane complexes as the cisplatin analogues of palladium series. They were characterized by means of elemental analysis, IR and NMR spectroscopy. As a result, the dicarboxylate ligands were conformed to be chelated with Pd(II) within the scope studied. The stability differences beween the dicarboxylato complexes according to the chelate ring size could not be differentiated due to generally lower thermodynamic stability of the dicarboxylato Pd(II) complexes.

• Journal of Information Display
• /
• v.8 no.2
• /
• pp.15-19
• /
• 2007

We have studied the effect of host materials on the electrophosphorescence properties by comparing three different host materials such as tris(8-hydroxyquinoline)-aluminum (III) $(Alq_3)$, bis(8-hydroxyquinoline)-zinc (II) $(Znq_2)$, and 4,4'-N,N' dicarbazole-biphenyl (CBP) doped with a red-emissive phosphorescent dye, 2,3,7,8,12,13,17,18-octaethyl-21H,23H-porphyrin platinum (II) (PtOEP). The EL spectra show a strong red emission (peak at 650 nm) from the triplet excited state of PtOEP and a very weak emission from an electron transport layer of $Alq_3$ and a hole transport layer of N,N'-diphenyl-N,N'-bis(3-methylphenyl)-1,1-biphenyl-4,4'-diamine (TPD). We find that the triplet exciton lifetime and the quantum efficiency decrease in the order of CBP, $Alq_3$, and $Znq_2$ host materials. The results are interpreted as a poor exciton confinement in $Alq_3$, and $Znq_2$ host compared with in CBP. Therefore, it is very important for the triplet-exciton confinement in the emissive layer for obtaining a high efficiency.

• Journal of the Korean Chemical Society
• /
• v.56 no.6
• /
• pp.679-691
• /
• 2012

New series of metal complexes of Co(II), Ni(II), Cu(II), Zn(II), Pd(II) and Pt(II) with 4-(p-chlorophenyl)-1-(pyridin-2-yl)thiosemicarbazide (HCPTS) have been synthesized and characterized by elemental analyses, magnetic moment, spectra (IR, UV-Vis, $^1H$ NMR, mass and ESR) and thermal studies. The IR data suggest different coordination modes for HCPTS which behaves as a monobasic bidentate with all metal ions except Cu(II) and Zn(II) which acts as a monobasic tridentate. Based on the electronic and magnetic studies, Co(II), Cu(II), Pd(II) and Pt(II) complexes have square - planner, Ni(II) has mixed stereochemistry (tetrahedral + square planar), while Zn(II) is tetrahedral. Molar conductance in DMF solution indicates the non-ionic nature of the complexes. The ESR spectra of solid copper(II) complex show $g_{\parallel}$ (2.2221) > $g_{\perp}$ (2.0899) > 2.0023 indicating square-planar structure and the presence of the unpaired electron in the $d_x2_{-y}2$ orbital with significant covalent bond character. The thermal stability and degradation kinetics of the ligand and its metal complexes were studied by TGA and DTA and the kinetic parameters were calculated using Coats-Redfern and Horowitz-Metzger methods. The complexes have more antibacterial activity against some bacteria than the free ligand. However, the ligand has high anticancer activities against HCT116 (human colon carcinoma cell line) and HEPG2 (human liver hepatocellular carcinoma cell line) compared with its complexes.

• Transactions of the Korean hydrogen and new energy society
• /
• v.27 no.3
• /
• pp.264-269
• /
• 2016

A simple dry chemical approach was developed in order to load palladium (Pd) as a promoter on Pt/gas diffusion electrode (GDE) for polymer electrolyte membrane fuel cell (PEMFC). Palladium(II) bis (acetylacetonate), $Pd(acac)_2$ was sublimed, penetrated into Pt/GDE and then reduced to Pd nanoparticles simultaneously without any reducing agent and any solvent in a glass reactor of $N_2$ atmosphere at $180^{\circ}C$ for 3, 5 and 15 min. Pd distribution was analyzed by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS), and I-V curve was estimated by using a unit cell with $5{\times}5cm^2$ active area.

• Journal of the Korean Chemical Society
• /
• v.28 no.6
• /
• pp.399-402
• /
• 1984

The S-enantiomer of the 6,6'-dimethyl-2,2'-dia minobiphenyl (dmdabp) has been obtained by resolving dmdabp with l-tartaric acid. The square planar dichloro platinum(II) complex has been prepared with the optically active S-dmdabp, which is found to take the conformation in the [Pt(S-dmdabp)Cl$_2]$ complex.