• Title/Summary/Keyword: Pseudo precocious puberty

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The Physical growth and secretion of sex hormone in girls with Idiopathic precocious puberty (특발성 성조숙증 여아의 유형별 분류에 따른 신체발육 및 성호르몬 분비)

  • Kwon, Mi-Young;Kim, Myung
    • Journal of Digital Convergence
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    • v.12 no.9
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    • pp.283-290
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    • 2014
  • Recently, As the prevalence of precocious is increased in Korea This study was evaluated the physical growth and female sex hormone characteristics of girls with Idiopathic precocious puberty. Retrospective analysis about the medical record of 113 girls for evaluation of signs of precocious puberty except for organic causes was done. Physical growth features and Female sexual hormone were analyzed. Height SDS and Weight SDS were significantly increased in true sexual precocity compared to pseudo sexual precocity. Hormone studies showed that the level of basal LH, FSH, E2 was significantly higher in true precocious puberty. The finding of this study suggest that we need to develop intervention about physical and psychological problems for precocious puberty girls.

Diagnosis and constitutional and laboratory features of Korean girls referred for precocious puberty

  • Kim, Doosoo;Cho, Sung-Yoon;Maeng, Se-Hyun;Yi, Eun Sang;Jung, Yu Jin;Park, Sung Won;Sohn, Young Bae;Jin, Dong-Kyu
    • Clinical and Experimental Pediatrics
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    • v.55 no.12
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    • pp.481-486
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    • 2012
  • Purpose: Precocious puberty is defined as breast development before the age of 8 years in girls. The present study aimed to reveal the diagnosis of Korean girls referred for precocious puberty and to compare the constitutional and endocrinological features among diagnosis groups. Methods: The present study used a retrospective chart review of 988 Korean girls who had visited a pediatric endocrinology clinic from 2006 to 2010 for the evaluation of precocious puberty. Study groups comprised fast puberty, true precocious puberty (PP), pseudo PP, premature thelarche, and control. We determined the height standard deviation score (HSDS), weight standard deviation score (WSDS), and body mass index standard deviation score (BMISDS) of each group using the published 2007 Korean growth charts. Hormone tests were performed at our outpatient clinic. Results: The PP groups comprised fast puberty (67%), premature thelarche (17%), true PP (15%), and pseudo PP (1%). Advanced bone age and levels of estradiol, basal luteinizing hormone (LH), and peak LH after gonadotropin-releasing hormone stimulation testing were significantly high in the fast puberty and true PP groups compared with the control group. HSDS, WSDS, and BMISDS were significantly higher in the true PP group than in the control group (P<0.05). Conclusion: The frequent causes of PP were found to be fast puberty, true PP, and premature thelarche. Furthermore, BMISDS were significantly elevated in the true PP group. Therefore, we emphasize the need for regular follow-up of girls who are heavier or taller than others in the same age group.