• Asian-Australasian Journal of Animal Sciences
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• v.32 no.4
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• pp.494-500
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• 2019

Objective: Feed consumption contributes a large percentage for total production costs in the poultry industry. Detecting genes associated with feeding traits will be of benefit to improve our understanding of the molecular determinants for feed efficiency. The objective of this study was to identify candidate genes associated with feed conversion ratio (FCR) via genomewide association study (GWAS) using sequence data imputed from single nucleotide polymorphism (SNP) panel in a Chinese indigenous chicken population. Methods: A total of 435 Chinese indigenous chickens were phenotyped for FCR and were genotyped using a 600K SNP genotyping array. Twenty-four birds were selected for sequencing, and the 600K SNP panel data were imputed to whole sequence data with the 24 birds as the reference. The GWAS were performed with GEMMA software. Results: After quality control, 8,626,020 SNPs were used for sequence based GWAS, in which ten significant genomic regions were detected to be associated with FCR. Ten candidate genes, ubiquitin specific peptidase 44, leukotriene A4 hydrolase, ETS transcription factor, R-spondin 2, inhibitor of apoptosis protein 3, sosondowah ankyrin repeat domain family member D, calmodulin regulated spectrin associated protein family member 2, zinc finger and BTB domain containing 41, potassium sodium-activated channel subfamily T member 2, and member of RAS oncogene family were annotated. Several of them were within or near the reported FCR quantitative trait loci, and others were newly reported. Conclusion: Results from this study provide valuable prior information on chicken genomic breeding programs, and potentially improve our understanding of the molecular mechanism for feeding traits.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.847-850
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• 2012

Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8 or TIPE) is a recently identified protein considered to be associated with carcinogenesis. To investigate its expression pattern in pancreatic cancer patients and to analyse its correlation with clinicopathological significance and the expression levels of epithelial growth factor receptor (EGFR), immunohistochemistry was performed to detect the TNFAIP8 and EGFR proteins in pancreatic cancers, pancreatitis tissues, and healthy controls. The results showed stronger staining of TNFAIP8 protein in pancreatic cancer tissues compared with normal pancreas tissue. Furthermore, in 56 patients with pancreatic cancer, the expression levels of TNFAIP8 in patients with low tumor stage was higher than that with high tumor stage, and correlated with tumor staging and lymph node metastasis (P<0.05). Furthermore, TNFAIP8 expression positively correlated with EGFR levels (r=0.671135, P<0.05). These results indicate that TNFAIP8 may play important roles in the progression of pancreatic cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.3
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• pp.1025-1028
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• 2015

Background: Prostate cancer is one of the main causes of cancer death, and drug resistance is the leading reason for therapy failure. However, how this occurs is largely unknown. We therrfore aimed to study the response of DU145 cells to cisplatin. Materials and Methods: Du145 prostate cancer cells were treated with a low dose of cisplatin for 24 h and cell viability and number were determined by MTT assay and trypan blue exclusion assay, respectively. The real time polymerase chain reaction (PCR) was used to assess responses to cisplatin treatment. Results: After 24h $2{\mu}g/ml$ treatment did not result in significant reduction in cell viability or number. However, it led to enhanced cancer cell invasiveness. E-cadherin mRNA was reduced, and vimentin, Snail, Slug, metalloproteinase 9 (MMP9) mRNA expression increased significantly, a feature of epithelial-mesenchymal transition (EMT). Conclusions: Short time low concentration cisplatin treatment leads to elevated invasiveness of DU145 cancer cells and this is possibly due to EMT.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.3
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• pp.1510-1532
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• 2017

In smart grid, privacy implications to individuals and their families are an important issue because of the fine-grained usage data collection. Wireless communications are utilized by many utility companies to obtain information. Network coding is exploited in smart grids, to enhance network performance in terms of throughput, delay, robustness, and energy consumption. However, random linear network coding introduces a new challenge for privacy preserving due to the encoding of data and updating of coefficients in forwarder nodes. We propose a distributed privacy preserving scheme for random linear network coding in smart grid that considers the converged flows character of the smart grid and exploits a homomorphic encryption function to decrease the complexities in the forwarder node. It offers a data confidentiality privacy preserving feature, which can efficiently thwart traffic analysis. The data of the packet is encrypted and the tag of the packet is encrypted by a homomorphic encryption function. The forwarder node random linearly codes the encrypted data and directly processes the cryptotext tags based on the homomorphism feature. Extensive security analysis and performance evaluations demonstrate the validity and efficiency of the proposed scheme.

• Korean Journal of Soil Science and Fertilizer
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• v.47 no.2
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• pp.71-79
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• 2014

Climate change has been social and environmental issues, it typically indicates the trend changes of not only temperature but also rainfall. There is a need to consider climate changes in a long-term soil erosion estimation since soil loss in a watershed can be varied by the changes of rainfall intensity and frequency of torrential rainfall. The impacts of rainfall trend changes on soil loss, one of climate changes, were estimated using Sediment Assessment Tool for Effective Erosion Control (SATEEC) employing L module with current climate scenario and future climate scenario collected from the Korea Meteorological Administration. A 62 $km^2$ watershed was selected to explore the climate changes on soil loss. SATEEC provided an increasing trend of soil loss with the climate change scenarios, which were 182 ton/ha/year in 2010s, 169 ton/ha/year in 2020s, 192 ton/ha/year in 2030s,182 ton/ha/year in 2040s, and 218 ton/ha/year in 2050s. Moreover, it was found that approximately 90% of agricultural area in the watershed displayed the soil loss of 50 ton/ha/year which is exceeding the allow able soil loss regulation by the Ministry of Environment.

• Proceedings of the KAIS Fall Conference
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• 2011.12a
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• pp.231-234
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• 2011

현재 상용화 중인 4세대 이동통신의 사용자가 급증하고 있다. 현재 4세대 이동통신 국내 가입자는 천만 명이 넘어섰으며, 4세대 이동통신에 어느 기술이 사용이 되고 데이터 전송속도가 얼마나 빠른지 알고 사용하는 사람은 많지 않다. 따라서 본 논문에서는 4세대 이동통신에 사용되고 있는 3GPP계열의 LTE-Advanced와 와이맥스 계열의 IEEE802.16m의 데이터 전송속도 기반의 이론적인 속도값과 현재 상용화된 4세대 이동통신의 데이터 전송속도의 실제 측정값을 비교, 분석하여 상호간의 특징적 차이를 분석하는 연구를 수행하였다.

• Proceedings of the KAIS Fall Conference
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• 2011.12a
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• pp.235-237
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• 2011

현대 사회에서 대부분의 사람들이 SNS 어플리케이션을 선호하고 자주 이용하고 있다. 그 동안 삐삐, 휴대폰, 문자, 싸이월드&메신저 등 커뮤니케이션의 도구가 진화해왔으나 점차적으로 단순화를 추구하는 경향이 증가하고 있다. 또한, 인터넷을 이용한 인간관계가 대중화되면서 삶을 살아가는데 있어 SNS(Social Networking Service)는 매우 중요한 요소가 되고 있다. 따라서 본 논문에서는 현대 사회에서 SNS에 열광하는 이유와 SNS의 사용목적, 선호도 등을 설문 방식의 적용으로 조사, 분석하는 연구를 수행하였다.

• Bulletin of the Korean Chemical Society
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• v.35 no.11
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• pp.3326-3330
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• 2014

A quinoline-thiooxorhodamine conjugate fluorescent sensor (1) has been synthesized. Sensor 1 exhibits high selectivity and sensitivity to $Hg^{2+}$ in $H_2O$/DMSO (95/5, v/v, HEPES 20 mM, pH = 7.4) solution with fluorescence detection. Other tested metal ions do not induce any significant fluorescence intensity changes. Sensor 1 interacts with $Hg^{2+}$ through a 1:1 binding stoichiometry with a good anti-inference ability. In addition, fluorescent imaging of $Hg^{2+}$ in Hela cells is also successfully demonstrated.

• Bulletin of the Korean Chemical Society
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• v.35 no.8
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• pp.2326-2330
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• 2014

A carbazole-based Schiff base CB2 was synthesized and applied as a highly selective and sensitive fluorescent probe for $Cu^{2+}$ in $H_2O$-DMSO (8/2, v/v, pH = 7.4) solution. CB2 exhibits an excellent selectivity to $Cu^{2+}$ over other examined metal ions with a prominent fluorescence "turn-on" at 475 nm. CB2 and $Cu^{2+}$ forms a 1:2 binding ratio complex with detection limit of $9.5{\mu}M$. In addition, the $Cu^{2+}$ recognition process is hardly interfered by other examined metal ions.

• Bulletin of the Korean Chemical Society
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• v.35 no.2
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• pp.392-396
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• 2014

New organic-inorganic composite of 2,4-dihydroxybenzophenone (BP-1) encapsulation into dodecylbenzenesulfonate (DBS) modified layered double hydroxide (LDH) was successfully prepared. The surface, structural, thermal and absorption properties of the BP-1/DBS-LDH nanohybrid was characterized by BET analysis, scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TG) and diffuse reflectance UV-Vis absorbance spectra (DRUV-vis). The interlayer configuration of composite and the adsorption mechanism of BP-1 on MgAl-DBS-LDH were discussed. It was suspected that DBS anions located in the form of monolayer arrangement with a $75^{\circ}$ anti parallel angle between dodecylbenzenesulfonate chain axis. The diffuse reflectance UV-Vis absorbance results revealed that the UV absorbing wavelength of BP-1/DBS-LDH evidently extends to about 400 nm, which shows that the BP-1/DBS-LDH has the potential application as a UV absorber.