• Journal of Korean Medicine for Obesity Research
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• v.17 no.1
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• pp.37-45
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• 2017

Recently the global epidemic problem of obesity has stimulated intense interest in the study of physiological mechanisms using animal models as a way to gain crucial data required for translation to human studies. Panax ginseng has been reported to have anti-obesity or antidiabetic effects in many animal studies; however, there have been few studies investigating human obesity. Herein, we will assess and examine the evidence supporting the anti-obesity effect of Panax ginseng in animal models with respect to anthropometric and metabolic outcomes. We will include controlled, comparative studies assessing the effect of Panax ginseng in preclinical studies of obesity. Panax ginseng will be administered during or following the induction of experimental obesity. The primary outcome measure will be anthropometric assessment and the secondary outcome measures will include adipose tissue weight, total amount of food consumed and metabolic parameters. We will search MEDLINE, Embase, PubMed, Web of Science, and Scopus without language, publication date, or other restrictions. Ethical approval will not be necessary as the data collected in this study will not be individual patient data, consequently there will be no concerns about violations of privacy. After finishing the whole procedure, the results will be disseminated by publication in a peer-reviewed journal or presented at a relevant conference. This protocol has been registered on the Collaborative Approach to Meta-Analysis and Review of Animal Data from Experimental Studies (CAMARADES) website (http://www.camarades.info).

• The KIPS Transactions:PartC
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• v.12C no.7 s.103
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• pp.1031-1038
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• 2005

As the research on home network technologies, sensor network technologies, and ubiquitous network technologies makes rapid progresses, wireless ad-hoc network have attracted a lot of attention. A wireless ad-hoc network is a temporary network formed by a collection of wireless mobile nodes without the aid of my existing network infrastructure or centralized administration, and it is suitable for ubiquitous computing environments. In this paper, we suggest an interconnection scheme between the wireless ad-hoc network environment based on multiple path source routing protocol and a Mobile-IP based network environment. This scheme reduces the overhead of route re-establishment and re-registration by maintaining multiple paths between the mobile host in wireless ad-hoc network and the base station in mobile-IP network. Also it puts the base station in charge of function that performs translation between wireless ad-hoc network packets and Mobile-IP packets, reducing the load of mobile hosts. In this paper, our simulations show that our scheme outperforms existing interconnecting schemes with regards to throughput and end-to-end delay Also we show that our scheme outperforms multi-paths approach using disjoint routes with regards to routing overhead.

• The Transactions of the Korea Information Processing Society
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• v.4 no.7
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• pp.1821-1841
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• 1997

This paper presents an automated protocol conformance test sequence generation based on formal methods for LOTOS specification by using and applying many existing related algorithms and technique, such as the testing framework, Rural Chinese Postman tour concepts. We use the state-transition graphs obtained from LOTOS specifications by means of the CAESAR tool. This tool compiles a specification written in LOTOS into an extended Petri net, from which a transition graph of a event finite-state machine(EvFSM) including data is generated. A new characterizing sequence(CS), called Unique Event sequence(UE sequence) is defined. An UE sequence for a state is a sequence of accepted gate events that is unique for this state. Some experiences about UE sequence, partial UE sequence and signature are also explained. These sequences are combined with the concept of the Rural Chinese Postman Tour to obtain an optimal test sequence which is a minimum cost tour of the reference transition graph of the EvFSM. This paper also presents a fault coverage estimation experience of an automated method for optimized test sequences generation and the translation of the test sequence obtained by using our tool to TTCN notation are also given. A prototype of the proposed framework has been built with special attention to real application in order to generated the executable test cases in an automatic way. This formal method on conformance testing can be applied to the protocols related to IN, PCS and ATM for the purpose of verifying the correctness of implementation with respect to the given specification.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.402-405
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• 2009

Digilog Book, the next generation publication material, supplies digitalized contents on an analog book by integrating digital contents into existing analog books. There are some studies related to authoring tools which are to authorize, and publish some books which provide digital contents by using VR or AR techniques. In this paper, a pen-type haptic user interface for Digilog Book authoring tool has been introduced. This haptic user interface is developed for more realistic and more effective authoring tasks. This haptic interface provides haptic effects for authoring tasks which are including translation, rotation, scaling, and menu selection. In this research, we designed a body, control circuits, vibration haptic patterns for haptic user interface, and a protocol for between haptic user interface and Digilog Book main control system. Also a simple user study has been done with a developed haptic user interface.

• Journal of Biomedical Engineering Research
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• v.27 no.6
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• pp.392-401
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• 2006

Image Guided Surgery (IGS) system which has variously tried in medical engineering fields is able to give a surgeon objective information of operation process like decision making and surgical planning. This information is displayed through 3D images which are acquired from image modalities like CT and MRI for pre-operation. The technique of image registration is necessary to construct IGS system. Image registration means that 3D model and the object operated by a surgeon are matched on the common frame. Major techniques of registration in IGS system have been used by recognizing fiducial markers placed on the object. However, this method has been criticized due to additional trauma, its invasive protocol inserting fiducial markers in patient's bone and generating noise data when 2D slice images are acquired by image modality because many markers are made of metal. Therefore, this paper developed shape-based registration technique to improve the limitation of fiducial marker based IGS system. Iterative Closest Points (ICP) algorithm was used to match corresponding points and quaternion based rotation and translation transformation using closed form solution applied to find the optimized cost function of transformation. we assumed that this algorithm were used in Total Knee replacement (TKR) operation. Accordingly, we have developed region-based 3D registration technique based on anatomical landmarks and this registration algorithm was evaluated in a femur model. It was found that region-based algorithm can improve the accuracy in 3D registration.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.45 no.3
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• pp.68-74
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• 2008

Ethernet is the very successful technology in private local area network. Therefore, we can obtain the advantage to reduce network overhead due to such as protocol translation when to apply Ethernet to the public backbone network. However, in order to do that, it is required to restore the network within 50msec when link failure occurs, in order to provide seamless connections to end users. Currently, ITU-T standardized the automatic protection switching (APS) based Ethernet protection switching system. In this paper, we propose the improved Ethernet protection switching system to minimize the number of Ethernet frames lost when the network is restored from the failure. The proposed mechanism is analyzed by using simulation based on ns-2 and numerical results show that the proposed one provides superior performance.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.25 no.5A
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• pp.751-762
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• 2000

In the forthcoming next generation highspeed networks, the provisioning of broadband mobile multimedia services is the most important issue while an efficient network management architecture, which can manage the network resources efficiently, is essential. The next generation highspeed networks will be composed of the ATMand SDH-based transport network systems and the H-based interworking systems. The management functions of these network systems are implemented various technologies, such as TMN and SNMP. In order to integrate these network resources efficiently with heterogeneous management functions, the distributed network management architecture such as TINA is most appropriate. In this pape, we propose an interworking architecture for TINA manager and TMN agent. where the TINA-based EML subnetwork management operations mapped into the related management operations of the TMN NE agent. The proposed interworking architecture is simpler than JIDM, and the processing overhead is minimized.

• The KIPS Transactions:PartD
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• v.13D no.2 s.105
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• pp.175-182
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• 2006

Radars are used to detect the motion of the low flying enemy planes in the military. Radar-detected raw data are first processed and then inserted into the ground tactical C4I system. Next, these data we analyzed and broadcasted to the Shooter system in real time. But the accuracy of information and time spent on the displaying and graphical computation are dependent on the operator's capability. In this paper, we propose the Flying Object Tracking Management System that allows the displaying of the objects' trails in real time by using data received from the radars. We apply the coordinate system translation algorithm, existing communication protocol improvements with communication equipment, and signal and information computation process. Especially, radar signal duplication computation and synchronization algorithm is developed to display the objects' coordinates and thus we can improve the Tactical Air control system's reliability, efficiency, and easy-of-usage.

• Archives of Pharmacal Research
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• v.29 no.10
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• pp.890-897
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• 2006

In inflammatory responses, induction of cytokines and other immune regulator genes in macrophages by pathogen-associated signal such as lipopolysaccharide (LPS) plays a crucial role. In this study, the gene expression profile changes by LPS treatment in the macrophage/monocyte lineage cell line RAW264.7 was investigated. A 60-mer oligonucleotide microarray of which probes target 32381 mouse genes was used. A reverse transcription-in vitro translation labeling protocol and a chemileuminescence detection system were employed. The mRNA expression levels in RAW264.7 cells treated for 6 h with LPS and the control vehicle were compared. 747 genes were up-regulated and 523 genes were down-regulated by more than 2 folds. 320 genes showing more than 4-fold change by LPS treatment were further classified for the biological process, molecular function, and signaling pathway. The biological process categories that showed high number of increased genes include the immunity and defense, the nucleic acid metabolism, the protein metabolism and modification, and the signal transduction process. The chemokine-cytokine signaling, interleukin signaling, Toll receptor signaling, and apoptosis signaling pathways involved high number of genes differentially expressed in response to LPS. These expression profile data provide more comprehensive information on LPS-target genes in RAW264.7 cells, which will be useful in comparing gene expression changes induced by extracts and compounds from anti-inflammatory medicinal herbs.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2001.10a
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• pp.97-100
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• 2001

For the auto-configuration of diverse hosts and automation of network management as many electronic machines and industrial components are becoming connected to Internet, it is possible to use autoconfiguration using DHCP and network management protocol such as SNMP, CMIP. But these technologies are not developed maturely and lack various standardizations yet because these are designed for restrictive purposes in the past. The new working group "Zeroconf" is made in IETF at March, 2000, it is aimed for making standards of autoconfiguration which is applied to impromptu ad-hoc networks in automobiles, trains, planes and home network or mobile networks. In this paper, we introduce the IPv6 based autoconfiguration technologies such as IP interface configuration, translation between host name and IP address, IP multicast address allocation and service discovery. Finally, trends of standardization in Zeroconf working group will be shown. be shown.