• Journal of Radiation Protection and Research
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• v.26 no.3
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• pp.249-253
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• 2001

Neutron dose assessment in criticality accidents using Whole Body Counter (WBC) was proved to be an effective method as rapid neutron dose estimation at the JCO criticality accident in Tokai-mura. The 1.36MeV gamma-ray of $^{24}Na$ in a body can be detected easily by a germanium detector. The Minimum Detectable Activity (MDA) of $^{24}Na$ is approximately 50Bq for 10miniute measurement by the germanium-type whole body counter at JNC Tokai Works. Neutron energy spectra at the typical shielding conditions in criticality accidents were calculated and the conversion factor, whole body activity-to-organ mass weighted neutron absorbed dose, corresponding to each condition were determined. The conversion factor for uncollied fission spectrum is 7.7 $[(Bq^{24}Na/g^{23}Na)/mGy]$.

• The KIPS Transactions:PartC
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• v.12C no.1 s.97
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• pp.77-82
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• 2005

Protection of user service becomes increasingly important since even very short interruption of service due to link or node failure will cause huge data loss and incur tremendous restoration cost in high speed network environment. Thus fast and efficient protection and restoration is one of the most important issues to be addressed. Protection methods have been proposed to provide efficiency and stability in optical networks. In this paper, an original network is separated into several domains using Hamiltonian cycle. and link protection is performed on the cycles of the domains. We have shown that protection path length can be decreased up to $57{\%}$ with marginal increase of backup capacity. Our proposed method can provide high-speed protection with marginal increase of protection capacity.

• Structural Engineering and Mechanics
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• v.62 no.4
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• pp.455-464
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• 2017

Rayleigh damping model is recommended in the recently developed Performance-Based Earthquake Engineering (PBEE) methodology, but this methodology does not provide sufficient information due to the complexity of the damping mechanism. Furthermore, each Rayleigh-type damping model may have its individual limitations. In this study, Rayleigh-type damping models that are used widely in engineering practice are discussed. The seismic performance of a large-span single-layer latticed dome subjected to earthquake ground motions is investigated using different Rayleigh damping models. Herein a simulation technique is developed considering low cycle fatigue (LCF) in steel material. In the simulation technique, Ramberg-Osgood steel material model with the low cycle fatigue effect is used to simulate the non-uniformly distributed material damping and low cycle fatigue damage in the structure. Subsequently, the damping forces of the structure generated by different damping models are compared and discussed; the effects of the damping ratio and roof load on the damping forces are evaluated. Finally, the low cycle fatigue damage values in sections of members are given using these damping models. Through a comparative analysis, an appropriate Rayleigh-type damping model used for a large span single-layer latticed dome subjected to earthquake ground motions is determined in terms of the existing damping models.

• Journal of fish pathology
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• v.35 no.2
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• pp.157-165
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• 2022

Single-cycle viruses generated by reverse genetic technology are replication-incompetent viruses due to the elimination of gene(s) essential for viral replication, which provides a way to overcome the safety problem in attenuated viruses. Infectious hematopoietic necrosis virus (IHNV) is a major pathogen causing severe damage in cultured salmonid species. In the present study, we generated a single-cycle IHNV lacking the transmembrane and cytoplasmic domain in the G gene (rIHNV-GΔTM) and evaluated the prophylactic potential of rIHNV-GΔTM in rainbow trout (Oncorhynchus mykiss). To produce rIHNV-GΔTM, IHNV G protein-expressing Epithelioma papulosum cyprini (EPC) cells were established. However, as the efficiency of rIHNV-GΔTM production in EPC cell clones was not high, fish were immunized with a low-tittered single-cycle virus (1.5 × 10² PFU/fish). Despite the low dose, the single-cycle IHNV induced significant protection in rainbow trout against IHNV infection, suggesting high immunogenicity of rIHNV-GΔTM. No significant difference in serum ELISA titers against IHNV between the rIHNV-GΔTM immunized group and the control group suggests that the immunized dose of rIHNV-GΔTM might be too low to induce significant humoral adaptive immune responses in rainbow trout. The involvement of adaptive cellular immunity or innate immunity in the present significantly higher protection by the immunization with rIHNV-GΔTM should be further investigated to know the protection mechanism.

• Journal of Radiation Protection and Research
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• v.25 no.3
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• pp.133-135
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• 2000

• Journal of KIISE:Information Networking
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• v.30 no.5
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• pp.668-675
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• 2003

In this paper, we propose an enhanced p-cycle (preconfigured protection cycle) scheme for WDM mesh networks with QoS constraints. In the previous researches on p-cycle, it is assumed that user's connection has a hi-directional connectivity and the same bandwidth on both direction. Therefore it is difficult to apply p-cycle based link protection to uni-directional connections for multicasting or asymmetric broadband multimedia communications with hi-directional connectivity. And it didn't consider QoS of backup path. We enhanced the p-cycles to accomodate uni-directional connections for multicasting or asymmetric bandwidth communications with hi-directional connectivity. And we propose a selection procedure of p-cycle to assure QoS of backup path. We were able to reduce a required backup bandwidth by applying a uni-directional p-cycle concept to asymmetric broadband multimedia communication environment. The proposed p-cycle selection procedure is applied to the U.S. sample network to evaluate whether the configured p-cycles can support QoS constraint of working path and backup path.

• Journal of Life Science
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• v.16 no.4
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• pp.699-703
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• 2006

Maize (Zea mays L.) is a monoecious plant, which separates male (tassel) and female (ear) floret that evolved into increasing heterogeneity. In each floret, male or female, bears both one pistil and three stamens primodia before diverged to unisexual state. When diverged to tassel, pistil cell death occurs in the pistil primodium, which is mediated by TASSELSEED genes. In contrast, cell protection occurs in the ear pistil from TASSELSEED-mediated cell death, which is mediated by SILKLESS1 gene. On the other hand, cell cycle arrest occurred for a long time in the ear stamens and then the stamens eventually dye. The cell cycle regulating genes such as CYCLIN B and WEE1 are involved in this process. Furthermore, the temporal and spatial regulation of gibberellin biosynthesis may cause cell cycle block in arresting stamen cells. This review describes the cell death, cell protection, and cell cycle arrest mechanism during maize sex determination process at the molecular, cellular and developmental biology, and genetic levels.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.3B
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• pp.200-208
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• 2003

In this paper, we propose an enhanced p-cycles (preconfigured protection cycles) scheme for fast restoration in WDM (Wavelength Division Multiplexing) optical mesh network with limited wavelength conversion for fast restoration. We enhanced the p-cycles to accommodate uni-directional connections to be used in uni-directional multicasting or asymmetric broadband multimedia communications with bi-directional connectivity. We applied it to WDM network with limited wavelength conversion and analyzed the result. The analysis results show that the enhanced p-cycle algorithm provides better performance in WDM optical networks with limited wavelength converter.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1299-1308
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• 2016

Our previous studies clearly demonstrated that a combination of WP 631 and Epo B has higher activity against ovarian cancer cells than either of these compounds used separately. In order to fully understand the exact mechanism of action in combination, we assessed effects on the cell cycle of SKOV-3 cells. We evaluated three control points essential for WP 631 and Epo B action to determine which cell cycle-regulating proteins (CDK1/cyclin B complex, EpCAM or HMGB1) mediate activity. The effects of the drug on the cell cycle were measured based on the nuclear DNA content using flow cytometry. Expression of cell cycle-regulating genes was analyzed using real-time PCR. It was discovered that WP 631, at the tested concentration, did not affect the SKOV-3 cell cycle. Epo B caused significant G2/M arrest, whereas the drug combination induced stronger apoptosis and lower mitotic arrest than Epo B alone. This is very important information from the point of view of the fight against cancer, as, while mitotic arrest in Epo B-treated cells could be overcame after DNA damage repair, apoptosis which occurs after mitotic slippage in combination-treated cells is irreversible. It clearly explains the higher activity of the drug combination in comparison to Epo B alone. Epo B acts via the CDK1/cyclin B complex and has the ability to inhibit CDK1, which may be a promising strategy for ovarian cancer treatment in the future. The drug combination diminishes EpCAM and HMGB1 expression to a greater degree than either WP 631 and Epo B alone. Owing to the fact that the high expression of these two proteins is a poor prognostic factor for ovarian cancer, a decrease in their expression, observed in our studies, may result in improved efficacy of cancer therapy. The presented findings show that the combination of WP 631 and Epo B is a better therapeutic option than either of these drugs alone.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2005.05a
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• pp.13-16
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• 2005

Generally, as corrosive protection processing of a steel structure, zinc galvanizing and heavy duty coating paint are applied. However, zinc galvanizing has the difficulty of restriction of a size, or on-site construction. Moreover, heavy duty coating paint has a problem with many administrative and maintenance expenses with short problem of adhesion, corrosion generating of a damage portion, and maintenance management cycle. In this study, a salt water spray test, CASS test, and the electrochemistry examination were carried out for the thermal metal spray method of construction for corrosive protection performance evaluation. Moreover, the corrosive protection life of a thermal metal spray method of construction was quantitatively calculated on the basis of this experiment. in consideration of LCC, the economical efficiency of a general corrosive protection method of construction and a thermal metal corrosive protection method of construction was compared. Consequently, although initial construction expense was estimated 16 to $30\%$ high, as for a thermal metal spray method of construction, it turns out that the administrative and maintenance expenses for 100 years became cheap 9.3 to 13 or more times.