• 제목/요약/키워드: Prospective authors

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The Merits of Mannitol in the Repair of Orbital Blowout Fracture

  • Shin, Kyung Jin;Lee, Dong Geun;Park, Hyun Min;Choi, Mi Young;Bae, Jin Ho;Lee, Eui Tae
    • Archives of Plastic Surgery
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    • 제40권6호
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    • pp.721-727
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    • 2013
  • Background One of the main concerns in orbital blowout fracture repair is a narrow operation field, due mainly to the innate complex three dimensions of the orbit; however, a deep location and extensive area of the fracture and soft tissue edema can also cause concern. Swelling of the orbital contents progresses as the operation continues. Mannitol has been used empirically in glaucoma, cerebral hemorrhage, and orbital compartment syndrome for decompression. The authors adopted mannitol for the control of intraorbital edema and pressure in orbital blowout fracture repair. Methods This prospective study included 108 consecutive patients who were treated for a pure blowout fracture from January 2007 to October 2012. For group I, mannitol was administered during the operation. Under general anesthesia, all patients underwent surgery by open reduction and insertion of an absorbable mesh implant. The authors compared postoperative complications, the reoperation rate, operation time, and surgical field improvement between the two groups. Results In patients who received intraoperative administration of mannitol, the reoperation rate and operation time were decreased; however, the difference was not statistically significant. The total postoperative complication rates did not differ. Panel assessment for the intraoperative surgical field video recordings showed significantly improved vision in group I. Conclusions For six years, mannitol proved itself an effective, reliable, and safe adjunctive drug in the repair of orbital blowout fractures. With its rapid onset and short duration of action, mannitol could be one of the best methods for obtaining a wider surgical field in blowout fracture defects.

요추 척추관 협착증의 비수술적 치료에 대한 최근 국내·외 연구 동향 (Recent Domestic and International Trends on Non-Surgical Treatment of Lumbar Spinal Stenosis)

  • 김미현;박은상;황현호;이여경;송금주;권미리;강준혁
    • 한방재활의학과학회지
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    • 제31권3호
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    • pp.1-17
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    • 2021
  • Objectives The present study examined the recent domestic and international trends of non-surgical treatment of lumbar spinal stenosis (LSS). Methods The studies on non-surgical treatment of LSS were investigated via searching Korean web databases and PubMed. As a result, 39 studies were analyzed according to the authors, the types of study, the relationship to surgical treatment and the method of treatment. Results The first authors' occupations were identified as 17 doctors, 12 Korean medicine doctors, six physiotherapists, three chiropractic doctors and one doctor of science. The most common type of study in Korea was the case report and most of the studies were retrospective. Overseas, there were many prospective or experimental studies including randomized controlled trials (RCT). In Korea, non-surgical treatment was performed independently of surgical treatment in most cases. Among non-surgical treatments, the most researched treatment was traditional Korean medicine (TKM), followed by injection therapy, exercise therapy, and physical therapy. Conclusions Through this review, we can determine the effectiveness of TKM and its research direction. TKM should be studied experimentally including RCT and it should be conducted not only on acupuncture, but also on other treatment methods such as acupotomy, chuna, and herbal medicine. It is also necessary to conduct studies on TKM before and after surgery to compare the effects of surgery and TKM together, as well the effects on non-surgical treatments.

자살을 시도한 주요우울증 환자에서 혈청 콜레스테롤 농도의 저하 (Low Serum Cholesterol Level in Major Depression Patients with Suicidal Attempt)

  • 김용구;이헌정;곽동일
    • 생물정신의학
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    • 제3권2호
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    • pp.258-261
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    • 1996
  • Objective : Several studies hove suggested that reduction of cholesterol concentration and low cholesterol level increases suicide, homicide, and depression. The authors sought to determine whether low cholesterol is associated with a history of suicidal attempts among major depression patients. Method : The subjects were 105 patients with major depression, diagnosed according to the DSM-III-R criteria, and 105 age, sex matched healthy controls. Blood was token following overnight fast and serum cholesterol concentration were measured by a enzymatic method Results : The serum cholesterol level was significantly lower in the patients with major depression than in healthy controls($180.4{\pm}43.4mg/dl$ vs $199.7{\pm}35.8mg/dl$). And the serum cholesterol level was significantly lower in major depression patients with suicidal attempt than in major depression patients without suicidal attempt($156.7{\pm}38.2mg/dl$ vs $ 187.8{\pm}42.5mg/dl$) Conclusion : It is hypothesized that low cholesterol level is associated with depression by modifying the serotonin metabolism and the production of interleukin-2, low cholesterol concentration should be further investigated as a potential biological marker of suicidal risk in major depression. Prospective study with serial cholesterol determinations should be done.

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Organizational Justice, Job Satisfaction and Organizational Citizenship Behavior in Higher Education Institutions: A Research Proposition in Vietnam

  • Dong, Le Nguyen Thanh;Phuong, Nguyen Ngoc Duy
    • The Journal of Asian Finance, Economics and Business
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    • 제5권3호
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    • pp.113-119
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    • 2018
  • Higher Education Institutions (HEIs) are place contributing to the intellectual advancement of the nation, quality human resource, and to a number of socio-economic improvements for society and organizations. Despite facilitators and staffs are the bare-bone of HEIs, there is a scarcity of research, both conceptual and empirical, focusing on their organizational citizenship behaviors (OCB). To attempt to fill this gap, this article develops a conceptual model of OCB under influencing of organizational justice and job satisfaction. The prospective respondents were chosen randomly from HEIs (public and private). Individuals have been employed at least one year and above will be the unit of analysis in which the experimental test of the proposed model will be conducted. The results suggest that organizational citizenship behavior is one of the most important factor influence the organizational performance. Furthermore, the performance of HEIs does not affect only the national human resources, but also impact on national economy. In this context, a conceptual framework is proposed to study the determinants of organizational citizenship behavior in the form of organizational justice and job satisfaction. Additionally, the ultimate benefits of OCB through perceived organizational justice with job satisfaction as mediator is enlightened. Finally, the authors discuss the managerial implications of their research.

A Study on the Distribution of Information and High Technology Clusters : Kazakhstan's Experience

  • Kireyeva, Anel A.;Abilkayir, Nazerke A.;Tsoy, Alexandr A.
    • 유통과학연구
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    • 제16권4호
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    • pp.5-15
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    • 2018
  • Purpose - This study aims to identify of prospective areas for the formation of information and high technology clusters, and propose the new distribution of Kazakhstan's regions according to the innovative development and the ability to perceive IT products. Research design, data, and methodology - The application of scientific methods in this research will allow to systematize the available data, from both a theoretical and empirical perspective. In addition, the authors proposed methodological approaches, which have a three-tiered gradation: macro-level, meso-level and micro-level. Results - This study confirms the importance of using of proposed methods and its application for real data in order to the formation of IT and high technology clusters. Further, the obtained results allowed identifying of the distribution of Kazakhstan's regions by innovative development and specialization with using of HHI indexes. Conclusions - According to the results of this theoretical and empirical study proved that distribution of the regions of Kazakhstan and results of HHI indexes shows the power of the agglomeration effect. In addition, according to the conducted survey, we conclude that in Kazakhstan there are sufficient organizational and economic opportunities, trends and conditions for the formation of IT and high technology clusters.

침의 대조군연구에서 실험처치 보고에 대한 표준-STRICTA 권장안 및 침임상실험에서 최적의 치료, 거짓대조군 및 블라인딩에 관한 동의안 (STandards for Reporting Interventions in Controlled Trials of Acupuncture: The STRICTA Recommendations)

  • 이향숙;박종배;서정철;박히준;이혜정
    • Journal of Acupuncture Research
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    • 제19권6호
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    • pp.134-154
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    • 2002
  • Acupuncture treatment and control group interventions in parallel-group randomised trials of acupuncture are not always precisely reported. In an attempt to improve standards, an international group of experienced acupuncturists and researchers devised a set of recommendations, designating them STRICTA : STandards for Reporting Interventions in Controlled Trials of Acupuncture. In a further consensus-building round, the editors of several journals helped redraft the recommendations. These follow the CONSORT format, acting as an extension of the CONSORT guidelines for the specific requirements of acupuncture studies. Participating journals are publishing the STRICTA recommendations and requesting prospective authors to adhere to them when preparing reports for publication. Other journals are invited to adopt these recommendations. The intended outcome is that interventions in controlled trials of acupuncture will be more adequately reported, thereby facilitating an improvement in critical appraisal, analysis and replication of trials.

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Behaviour of bolted connections in concrete-filled steel tubular beam-column joints

  • Beena, Kumari;Naveen, Kwatra;Shruti, Sharma
    • Steel and Composite Structures
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    • 제25권4호
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    • pp.443-456
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    • 2017
  • Many authors have established the usefulness of concrete filled steel tubular (CFST) sections as compression members while few have proved their utility as flexural members. To explore their prospective as part of CFST frame structures, two types of connections using extended end plate and seat angle are proposed for exterior joints of CFST beams and CFST columns. To investigate the performance and failure modes of the proposed bolted connections subjected to static loads, an experimental program has been executed involving ten specimens of exterior beam-to-column joints subjected to monotonically increasing load applied at the tip of beam, the performance is appraised in terms of load deformation behaviour of joints. The test parameters varied are the beam section type, type and diameter of bolts. To validate the experimental behaviour of the proposed connections in CFST beam-column joints, finite element analysis for the applied load has been performed using software ATENA-3D and the results of the proposed models are compared with experimental results. The experimental results obtained agree that the proposed CFST beam-column connections perform in a semi-rigid and partial strength mode as per specification of EC3.

Prognostic Factors of Hemifacial Spasm after Microvascular Decompression

  • Kim, Hong-Rae;Rhee, Deok-Joo;Kong, Doo-Sik;Park, Kwan
    • Journal of Korean Neurosurgical Society
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    • 제45권6호
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    • pp.336-340
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    • 2009
  • Objective : The factors that influence the prognosis of patients with hemifacial spasm (HFS) treated by microvascular decompression (MVD) have not been definitely established. We report a prospective study evaluating the prognostic factors in patients undergoing MVD for HFS. Methods : From January 2004 to September 2006, the authors prospectively studied a series of 293 patients who underwent MVD for HFS. We prospectively analyzed a number of variables in order to evaluate the predictive value of independent variables for the prognosis of patients undergoing MVD. The patients were followed-up at regular intervals and divided into as cured and unsatisfactory groups based on symptom relief. Uni- and multivariate analyses were performed using logistic regression models. Results : A total 273 of 293 (94.2%) patients achieved symptom relief within one year after the operation. Intraoperatively, the indentation of the root exit zone was observed in 259 (88.5%) patients. Uni- and multivariate analyses revealed that the symptoms at postoperative 3 months (p<0.001) and indentation of the root exit zone (p=0.036) were associated with good outcomes. Conclusion : The intraoperative finding of root exit zone indentation will help physicians determine the prognosis in patients with HFS. To predict the prognosis of HFS, a regular follow-up period of at least 3 months following MVD should be required.

Understanding the importance of cerebrovascular involvement in Kawasaki disease

  • Yeom, Jung Sook;Cho, Jae Young;Woo, Hyang-Ok
    • Clinical and Experimental Pediatrics
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    • 제62권9호
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    • pp.334-339
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    • 2019
  • Kawasaki disease (KD) is a systemic vasculitis in infants and young children. However, its natural history has not been fully elucidated because the first case was reported in the late 1960s and patients who have recovered are just now entering middle age. Nevertheless, much evidence has raised concerns regarding the subclinical vascular changes that occur in post-KD patients. KD research has focused on coronary artery aneurysms because they are directly associated with fatality. However, aneurysms have been reported in other extracardiac muscular arteries and their fate seems to resemble that of coronary artery aneurysms. Arterial strokes in KD cases are rarely reported. Asymptomatic ischemic lesions were observed in a prospective study of brain vascular lesions in KD patients with coronary artery aneurysms. The findings of a study of single-photon emission computed tomography suggested that asymptomatic cerebral vasculitis is more common than we believed. Some authors assumed that the need to consider the possibility of brain vascular lesions in severe cases of KD regardless of presence or absence of neurological symptoms. These findings suggest that KD is related with cerebrovascular lesions in children and young adults. Considering the fatal consequences of cerebral vascular involvement in KD patients, increased attention is required. Here we review our understanding of brain vascular involvement in KD.

제 3 기의 진행성 비소세포 폐암에서의 MVP 복합 항암 용법과 다분할 방사선 치료 -추가 항암 요법에 대한 임의 선택- (MVP Chemotherapy and Hyperfractionated Radiotherapy for Stage III Unresectable Non-Small Cell Lung Cancer - Randomized for Maintenance Chemotherapy vs. Observation; Preliminary Report)

  • 최은경;장혜숙;서철원;이규형;이정신;김상희;최철준;고윤석;김우성;김원동;김삼현;손광현
    • Radiation Oncology Journal
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    • 제9권2호
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    • pp.215-219
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    • 1991
  • 제3기의 진행성 비소세포 폐암에서의 MVP항암 요법과 다분할 방사선 치료의 효과를 판정하기 위하여 1991년 1월부터 전향성 임의선택 연구(prospective randomized study)를 시작하였다. 본 연구는 제III기의 비소세포 폐암중 절제가 불가능한 환자를 대상으로 하여 MVP 항암요법(Mitomycin C 6mg/$m^2$, Vinblastine 6 mg/$m^2$, Cisplatin 60 mg/$m^2$)을 3회 시행한 후 다분할 방사선치료 (120 cGy/ft BID)를 6500 cGy까지 조사하였다. 방사선치료가 끝난 1개월 후 관해정도를 확인하여 추가 항암요법을 시행하는 군과 계속 관찰하는 군으로 임의 분류하였다. 1991년 8월까지 18명의 환자가 등록 되었으며 이중 2명은 2cycle의 항암요법 후 치료를 포기하여 16명의 환자에 대한 분석을 시행하였다. MVP항암요법에 대한 관해율은 $62.5\%$$50\%$에서는 부분관해 $12.5\%$에서는 minimal response를 보였다. 항암요법에 부분관해를 보인 3명중 1명에서는 방사선 치료후 완전관해를 보였으며 항암요법으로 병이 진행된 6명의 환자중 4명에서는 방사선 치료후에도 역시 병이 진행되는 것을 알 수 있었다. 모든 환자는 다분할 방사선 치료를 잘 견뎠으나 한 환자가 방사선 치료 한달 후 항암요법과 관련된 부작용으로 사망하였다. 아직 추적관찰 기간이 짧고 대상 환자가 많지 않다는 문제점은 있으나 본 연구를 계속 진행함으로써 유의한 결과를 얻을 수 있을 것으로 기대된다.

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