• Title/Summary/Keyword: Propargylamines

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A Simple and Efficient One-Pot Three-Component Synthesis of Propargylamines Using Bismuth (III) Chloride

  • Teimouri, Abbas;Chermahini, Alireza Najafi;Narimani, M.
    • Bulletin of the Korean Chemical Society
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    • v.33 no.5
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    • pp.1556-1560
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    • 2012
  • A simple highly versatile and efficient method has been developed for the three-component coupling of aldehydes, amines and alkynes to prepare propargylamines, in the presence of a catalytic amount of $BiCl_3$. The advantages of methods are high yield, mild reaction conditions, no environmental pollution and easy work up procedure.