• Preventive Nutrition and Food Science
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• 제10권1호
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• pp.95-102
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• 2005

The term pharmacognosy as applied to a constituent scientific discipline of Korean Medical Food (KMF) has been in use for nearly several years, and it refers to studies on the pharmacological properties of natural products foods. During the last half of the 20th century, pharmacognosy for KMF evolved from being a descriptive botanical subject to one having a more chemical and biological focus. At the beginning of the 21st century, teaching pharmacognosy for KMF teaching in academic culinary arts and natural healing institutions has been given new relevance as a result of the explosive growth in the use of herbal foods (health foods) in modern KMF practice. In turn, pharmacognosy for KMF research areas are continuing to expand, and now include aspects of cellular and molecular biology in relation to natural products, ethnobotany and phytotherapy, in addition to the more traditional analytical method development and phytochemistry. Examples are provided in this review of promising bioactive compounds obtained in two multidisciplinary natural product KMF development and discovery projects, aimed at the elucidation of new plant-derived cancer chemotherapeutic agents and novel cancer chemopreventives, respectively. The systematic study of KMF offers pharmacognosy groups an attractive new area of research, ranging from investigating the biologically active principles of KMF and their mode of action and potential active substance interactions, to sanitary and quality control, and involvement in clinical trials.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2000년도 춘계학술대회 논문집
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• pp.151-156
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• 2000

Ultra precision progressive die have used for above one million's lot size of production part. In the field of design and making tool for press working, the progressive die for sheet metal (STS 304, thickness : 0.5mm) is a specific division. In order to prevent the defects, the optimum design of the production part, strip layout, die design, die making and tryout etc. are necessary. They require analysis of many kinds of important factors, i.e. theory and practice of metal press working and its phenomena, die structure, machining condition for die making, die materials, heat treatment of die component, know-how and so on. In this study, we designed and constructed a progressive die of multi-stage and performed try out. Out of these processes the die development could be taken for advance. Especially the result of tryout and its analysis become the characteristics of this paper (part 1 and part 2) that nothing might be ever seen before such as this type of research method on all the processes. In the part 2 of this study we treated die making and tryout mostly.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2000년도 춘계학술대회 논문집
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• pp.46-50
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• 2000

The progressive die are multiple operations performed by means of a die having above two stages, on the each of stages performs a different operation as the sheet metal passes through the die hole. In the field of design and making tool for press working, the progressive die for sheet metal (STS 304, thickness : 0.5mm) is a specific division. In order to prevent the defects, the optimum design of the production part, strip layout, die design, die making and tryout etc. are necessary. They require analysis of many kinds of important factors, I. e. theory and practice of metal press working and its phenomena, die structure, machining condition for die making, die materials, heat treatment of die components, know-how and so on. In this study, we designed and constructed a progressive die of multi-stage and performed try out. Out of these processes the die development could be taken for advance. Especially the result of tryout and its analysis become the characteristics of this paper (part 1 and part 2) that nothing might be ever seen before such as this type of research method on all the processes. In the part 1 of this study we treated die design mostly.

• KDI Journal of Economic Policy
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• 제42권2호
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• pp.1-30
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• 2020

This paper analyzes how injunctions relate to patent hold-up problems. To this end, we present a simple model of licensing negotiations between a patent holder and a downstream firm in the shadow of litigation. More specifically, we consider the situation in which an injunction is granted as a matter of course if a patent is found valid and infringed upon in litigation, but the patent holder may be under-compensated due to aspects of the patent remedy system other than injunctions. We show that if the downstream user is unaware of the patent before any investment in initially designing its product, the patent hold-up problems created by injunction threats are worrisome when (i) the redesign process is costly, (ii) the degree of patent protection (by aspects of the patent remedy system other than injunctions) is sufficiently strong and (iii) the injunction is requested not to practice the patented technology exclusively but to collect excessive patent royalties. Even if the downstream user is aware of the patent before the initial investment, the patent hold-up problems do not disappear. The findings here imply that a discretionary approach is required towards denying injunctions against patent infringement. If the degree of patent protection is not sufficiently strong, denying injunctions can exacerbate the under-compensation problem. However, once patent protection improves enough (not necessarily perfectly), we may see a surge of patent hold-up problems, and it would be better to apply alternative patent remedies in place of injunctions when necessary. Lastly, we discuss several possible alternatives to injunctions and their pros and cons.

• 한국전자통신학회논문지
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• 제14권3호
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• pp.595-600
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• 2019

유아 및 저학년용 교육도구는 기술의 발달로 ICT기반의 디지털 기술이 융합되면서 스마트화 되고 있고 스마트 교육도구의 디지털 상호작용 기능은 학생들에게 보다 높은 몰입감과 재미를 선사해, 기존의 교육도구와는 전혀 다른 놀이형 도구로서 학습이 가능하다. 스마트 교육도구 구현에 활용되는 기술은 로봇공학, 컴퓨터공학, 프로그래밍 등 공학과 수학적 바탕으로 하는 학문에서 비롯되어, 그 자체로 교육 분야에 접목 될 수 있다. 본 논문에서는 현장교육에 활용되는 교육용 도구 로봇의 특성을 고려한 연구 개발 및 교육 현장에 최적화된 피지컬 컴퓨팅 기반의 제품을 설계 및 구현하여 로봇 시스템의 기반이 되는 센싱 정보처리와 소프트웨어 설계 및 프로그래밍 실습 교육을 위한 피지컬 교육이 가능하도록 개발하였다.

• Physical Therapy Rehabilitation Science
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• 제12권3호
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• pp.251-258
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• 2023

Objective: The practice of breathing exercises involves altering the depth and frequency of respiration. Strengthening respiratory muscles plays a crucial role in maintaining overall health and well-being. The efficiency of the respiratory system affects not only physical activity but also various physiological processes including cardiovascular health, lung function, and cognitive abilities. The study evaluated the reliability of the developed device for inspiratory/expiratory training using pressure sensors and Bluetooth connectivity with a smartphone application. Design: Design & development research Methods: The research methodology involved connecting a custom-made respiratory sensor to an IMT-PEP BIC Breath device. Various pressure conditions were measured, and statistical analyses were performed to assess reliability and consistency. Results showed high Intraclass Coefficient Correlation (ICC) values for both inspiratory and expiratory pressures, indicating strong test-retest reliability. The device was designed for ease of use and wireless monitoring through a smartphone app. Results: This study conducted at expiratory pressure confirmed the proper operation of the IMT/PEP breathing trainer at the specified pressure setting in the product. The pressure sensor demonstrated high test-retest reliability with an ICC value of 0.999 for both expiratory and inspiratory pressure measurements. Conclusions: The developed respiratory training device measured and monitored inspiratory and expiratory pressures, demonstrating its reliability for respiratory training. The system could be utilized to record training frequency and intensity, providing potential benefits for patients requiring respiratory interventions. Further research is needed to assess the full potential of the device in diverse populations and applications.

• 한국IT서비스학회지
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• 제11권4호
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• pp.251-262
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• 2012

Unit testing is one of the test levels, which tests an individual unit or a group of related units. Recently, in Agile Development or Safety-critical System Development, the unit testing plays an important role for the qualities. According to the definition of unit testing, it is supposed to be done by the developers of units. That is because test models for the unit testing refers to the structure of units, and others but its original developers hardly can understand the structures. However, in practice, unit testing is often asked to be done without the original developers. For example, it is when faults are revealed in customer sites and the development team does not exit any more. In this case, instead of original developers, other developers or test engineers take a product and test it. The unit testing done by a non-developer, who is not the original developer, would cause some difficulties or cause more cost. In this paper, we tests an open source, JTopas, as a non-developer, with building test models, implementing test codes, and executing test cases. To fit this experiment to practical testing situations, we designed it based on the practices of unit testing, which were surveyed through SPIN(Software Process Improvement Network). This paper analyzes which part of unit testing done by non-developers needs more effort compared to the unit testing done by original developers. And it concludes that Agile Development contributes on reducing the extra effort caused by non-developers, since it implements test codes first before developing source code. That means all the units have already included their own tests code when they are released.

• 미술이론과 현장
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• 제2호
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• pp.147-168
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• 2004

This study examined the role of interpretation with various practices in art museums to seek a new meaning and a concept of art museum today. The exploration of interpretation would he a starting point to discuss about on art museums with professionals in each art-related field. While museums recognize the concept of interpretation and the scope of the functions in different levels, the study focused on the practices of collecting and exhibiting that will entrust the museum new realms of activities toward the audience. In particular, its emphases are set force on the information on the collections via the museum's web sites, interpretation policies, and theories and methodologies in exhibition development. Art museum websites well reflect how museums utilize the new medium to enhance the understanding of art works by providing in-depth art historical information, comprehensive contexts, and subject/concept based search methods. In recent decades, these have enacted changes to expand dimensions of interpretive functions in most museums, particularly in the United States and others. In an administrative perspective, Tate Gallery Interpretation Policy became an good example how an art museum put its interpretation philosophy as the basis of interpreting collection and public programs. Tate established functions of intrepretation and education not only within a task-based team but also as an intrer-divisional coorperation to provide an interpretation scheme of information provisions such as guide brochure, audio tour, multimedia content, and library. New environment and trends of museum exhibition, and its development processes stem from communication theories, object interpretation philosophy, display strategies, and various evaluation techniques through audiences, with the communication theories of Shannon and Weaver, Berlo's SMCR(Source-Message-Channel-Receiver) models were perceived as to understand the mechanism to communicate museum exhibits to visitors Suzan vogel's insight into object display strategy helped to conceive the mechanism of object recontextualization. She emphasized that the museum's practice to construe opinions and impressions through object display should be discreet and critical, therefore, the professionals to plan the exhibition should reveal the intention and their practices. For a prevailing new methodology from the field, the interpretive exhibition development processes are articulated as the front-end, formative, and summative evaluation, futhermore the team process in industrial product management models was adapted. These have turned out to be more interactive with visitors and effective to communicate the exhibition concepts and messages, hence resulting in enriched museum experiences. Finally the study concluded that understanding the aspects of interpretation should help art museums to set a framework for current practices to expand its public dimension. It can provide curators with a critical view to website planning and its content. And obviously, the interpretive exhibition development methodology will lead museum exhibition developers to be skilled in its current approaches to thematic exhibition concerning diverse subjects and topics.

• 디자인학연구
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• 제13권1호
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• pp.209-218
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• 2000

본 연구의 목적은 2년제 대학 산업디자인과 제품, 환경디자인 전공 교육과정의 개선을 제안하는 데 있다. 이 목적을 이루기 위하여 2가지 방법을 수행하였다. 첫째는 주로 중소기업의 제품생산업체, 디자인 전문회사 등에 근무하는 디자이너의 직무를 설문 분석한 것이고, 둘째는 2년제 대학에 재직하는 전공교수들의 의견을 설문 조사하여 비교한 것이다. 그 결과는 다음과 같다. 1. 2년데 대학 산업디자인과의 수업연한은 현재대로 2년이 적합하다. 단 선택적으로 1년의 심화과정을 개설하는 것이 바림직하다. 2. 2년제 대학졸업자들은 현장에서의 실기와 관련된 능력에 강점을 보이고 있으나 응용력을 필요로 하거나 창조적인 업무에는 다소 어려움을 나타내고 있으므로 실제로 제품개발에 필요한 컴퓨터 조형 실기나 관련된 실험·실습은 계속적으로 강화하며, 또한 업무와 관련된 과목을 익힐 수 있도록 외국어나 생산공정, 신제품에 대한 지식, 소비자 행태 조사등에 관련된 선택과목의 폭을 넓혀야 한다. 3. 다음 영역의 교과는 그 과목의 내용이나 명칭. 시간의 조성이 필요하다. 컴퓨터 모델링, 컴퓨터 랜더링과 입체조형을 이해시킬 수 있는 실기과목 같은 제품개발의 입체적 조형작업에 관련된 교과의 요구가 높아졌고, 디자인 표현에 관련된 교과는 대부분 컴퓨터를 이용한 명칭과 내용으로 요구되고 있다. 개발 제품의 제시, 광고, 판매, 모니터링에 관련된 교과에서는 인쇄학, 상품학, 포장디자인, 타이포그래피, 사진 같은 제품의 광고, 판매에 관련된 교과의 요구는 낮아졌고, 개발 제품 디자인의 프리젠테이션 기법의 개설이 요구되고 있다. 현장 실습, 실무특강, 원서 강독 같은 기타 교과는 현행대로 유지하되, 형식에 치우치지 않는 실제적인 것이 되어야만 하고, 실무 디자이너들이 업무를 수행하는데 일반지식으로 가장 필요하다고 느끼는 것이 외국어이므로 실제적이고 지속적인 외국어 교육이 요구되고 있다.석한후 그 결과를 종합적으로 해석함으로써 더 유효성이 높은 접근 가능성을 모색하고자 하였다. 시스템 에서 포도당을 낮은 level로 유지할 수 있었으나, 초산의 과도한 축적으로 항체 생산성의 향상은 예상에 비해 크지 않았다. 81%), C18 0(12.38%), C18: 1(25.93%), C22:6(9.95%)이며 결합지방질(結合脂肪質)은 C14 : 0(11.60%), C16 : 0(18.94%), C16: 1(10.42%). C18 : 1(10.89%), C22 : 6(23.44%)이었다. 총필수지방산(總必須脂肪酸) 함량(含量)은 극성지방질(極成脂肪質)$(20.14{\sim}31.12%)$이 비극성지방질(非極成脂肪質)$(6.97{\sim}11.13%)$보다 훨씬 높았고, 결합지방질(結合脂肪質)이 유리지방질(遊離脂肪質)보다 높았으며 부위별(部位別)로는 피부(皮部)$(15.18{\sim}15.41%)$가 육질부(肉質部)$(6.97{\sim}11.13%)$보다 높았다. 또${\omega}3$고도부포화지방산(高度不飽和脂肪酸) 함량(含量)은 육질부(肉質部)$(15.15{\sim}28.32%)$가 피부(皮部)$(6.77{\sim}18.18%)$나 내장부(內臟部)$(8.35{\sim}9.74%)$보다 높았으며, 육질부(肉質部)에서는 극성지방질(極成脂肪質)$(26.28{\sim}34.18%)$이 비극성지방질(非極成脂肪質)$(15.15{\sim}28.32%)$보다 높았다.veral world-wide prediction models. Based on the analysis, we can easilty know the importance of the model choice to

• Nutrition Research and Practice
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• 제12권2호
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• pp.110-117
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• 2018

BACKGROUND/OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and is closely associated with metabolic syndrome. In the present study, we observed the effect of ethanol extract of Allium fistulosum (EAF) on NAFLD and have suggested the possibility of using EAF as a natural product for application in the development of a treatment for NAFLD. MATERIALS/METHODS: The preventive effect on hepatic lipid accumulation was estimated by using an oleic acid (OA)-induced NAFLD model in vitro and a Western diet (high-fat high-sucrose; WD)-induced obese mouse model. Animals were divided into three groups (n = 7): normal diet group (ND), WD group, and WD plus 1% EAF group. RESULTS: EAF reduced OA-stimulated lipid accumulation in HepG2 cells in the absence of cellular cytotoxicity and significantly blocked transcriptional activation of sterol regulatory element-binding protein 1 and fatty acid synthase genes. Subsequently, we investigated these effects in vivo in mice fed either ND or WD in the presence or absence of EAF supplementation. In comparison to the ND controls, the WD-fed mice exhibited increases in body weight, liver weight, epididymal fat weight, and accumulation of fat in hepatocytes, and these effects were significantly attenuated by EAF supplementation. CONCLUSIONS: Allium fistulosum attenuates the development of NAFLD, and EAF elicits anti-lipogenic activity in liver. Therefore, EAF represents a promising candidate for use in the development of novel therapeutic drugs or drug combinations for the prevention and treatment of NAFLD.