• Product Safety
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• s.189
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• pp.16-18
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• 2009

• Product Safety
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• s.184
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• pp.14-15
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• 2009

• Product Safety
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• s.200
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• pp.14-21
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• 2010

• Food Industry And Nutrition
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• v.21 no.1
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• pp.19-21
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• 2016

• Korean Journal of Pharmacognosy
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• v.48 no.4
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• pp.261-267
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• 2017

As part of the search for bioactive constituents of Korean medicinal plants, twelve steroids (1-12) were isolated from the rhizomes of Dioscorea nipponica. The isolated compounds were identified as diosgenin ($3{\beta}$, 25R)-spirost-5-en-3-ol (1), 25(R)-dracaenoside E (2), dioscin (3), gracillin (4), prosapogenin B (5), 25(R)-dracaenoside G (6), diosgenin 3-O-${\beta}$-D-glucopyranosyl($1{\rightarrow}3$)-${\beta}$-D-glucopyranoside (7), ophipogonin C′ (8), 7-oxodioscin (9), protodioscin (10), hypoglaucin F (11), and protoneogracillin (12). Their structures were characterized by spectroscopic data and identified by comparing these data with those in the literatures. All the isolates (1-12) were evaluated for their neuroprotective effects through induction of nerve growth factor in C6 glioma cells and effects on nitric oxide (NO) production in murine microglia cell line BV-2. Compounds 7 and 12 were found to induce upregulation of NGF secretion without causing significant cell toxicity and compound 4 exhibited potent anti-neuroinflammatory activity.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.7
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• pp.1750-1759
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• 2009

Recently from the enterprise when about reduction the product of numerous type to develop does not produce simultaneously with Life Cycle shortening and JIT productions of the product, is confronting in the environment which will not become. In order to confront in like this environment, developing the good product importance but, the product researches what kind of direction and developing with core subject of technical innovation is recognized. For the development method and an investment direction of the product proposed PPM (Product Portfolio Management) algorithms from the research which sees from like this viewpoint. With PPM algorithms which are proposed, divided the product in 6 kind groups of standardization type, discrimination type, material cost investigation type, processing cost investigation type and sale promotion type and abolition type and presented tyresearch and development direction..Research approach portfolio investigation of existing research and consulting experience of research and development field with background, presented the analytical model of algorithm, is applied of the instance which composed.

• Proceedings of the KIPE Conference
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• 1998.10a
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• pp.865-870
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• 1998

We propose a multifunctional power line compensator (PLC) which can individually compensate multiple impediments at the same time. The PLC has the flexibility to share power to each compensation according to commands, this improving the working rate. We constructed a 100kVA PLC model including a controller with digital signal processor (DSP) to realize a multifunctional compensation were obtained.

• Journal of the Korean Mathematical Society
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• v.35 no.2
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• pp.295-314
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• 1998

In this article we examine certain distinctive features regarding Hardy spaces of both classical and product notions on $R^{N}$ with our focus on their interrelations through embeddings and restrictions. Applications of our results to multiple singular integrals are included.d.

• Journal of Life Science
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• v.8 no.2
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• pp.216-225
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• 1998

Metal ion-induced and it’s regulatory genes were screened in virulent salmonella typhimurium UK1 and tested cross-regulation with various stresses. Using the techniqud of P22-MudJ(Km, lacZ)-directed lacZ operon fusion, LF40 cuiA::MudJ and Lf153 cuiD::MudJ which were induced by copper were selected. cuia and cuiD were determined anaerobic coper inducible and copper tolerance response gene, respectively. Also cuiA and cuiD locus were determined at 81 and 8min, respectively, on salmonella Genetic Map. The two regulators were identified as cuaR, and cudR, which controls cuiA and cuiD, respectively. cuaR, and cudR appeared as negative regulators because the expression of cuiA-lac-Z and cuiD-lacZ were increased. Copper adapted UK1 showed high resistance to H$_{2}$O$_{2}$, but cuiD did not. The product of the cudR locus was responsible for decreasing the tolerance to copper and H$_{2}$O$_{2}$. Furthemore cuiA and cuiD locus were found to be part of a regulon under the control of a trans-acting regulators, rpoS, oxyR and relA. Therefore, the results suggest CTR participate with oxidative stress on Salmonella.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.12 no.6
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• pp.139-150
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• 2017

In Korea, small and medium-sized enterprises (SMEs) play an pivotal role in the national economy, accounting for 99.9% of all enterprises, 87.9% of total employment, and 48.3% of production. In spite of their crucial role in the national development, most of SMEs suffer from a lack of R&D related resources. Public R&D organizations such as government-funded research institutes can provide SMEs with valuable supplementary technological knowledge and help them build technological capacity. In this regard, this study estimated the effect of internal R&D investment and private-public R&D cooperation on technological innovation of ICT SMEs based on 2016 ETRI Survey. Building on previous literatures, the study established and tested a research model using binary logistic regression analysis. First, internal R&D investment and preferences for open innovation demonstrated the strengthening of R&D collaboration. Second, internal R&D investment and R&D cooperation showed a positive effect on both product and process innovation. Therefore, internal R&D capability and taking advantage of R&D collaboration are needed to achieve technological innovation for SMEs in ICT sector. This study also discuss implications for encouraging private-public R&D cooperation.