• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5237-5242
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• 2013

Background: Inflammation is a critical component of tumor progression. Many cancers arise from sites of infection, chronic irritation, and inflammation. It is now becoming clear that the tumour microenvironment, which is largely orchestrated by inflammatory cells, is an essential participant in the neoplastic process, promoting proliferation, survival and migration. Platelets can release some growth factors such as platelet-derived growth factor, platelet factor 4, and thrombospondin. Such factors have been shown to promote hematogenous tumour spread, tumor cell adhesion and invasion, and angiogenesis and to play an important role in tumor progression. In this study, we aimed to investigate effects of the pretreatment neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) on survival and response to chemoradiotherapy in patients with non-small-cell lung cancer (NSCLC). Materials and Methods: Ninety-four patients with non-metastatic NSCLC were included and separated into two groups according to median valuse of NLR and PLR (low:<3.44 or high:${\geq}3.44$ and low:<194 or high${\geq}194$, respectively). Results: Pretreatment high NLR and PLR were associated with significantly shorter disease-free and overall survival rates. Multivariate analysis revealed that the overall survival rates were significantly linked with PLR (OR: 1.87, CI: 1.20-2.91, p: 0.006) and response to chemoradiotherapy (OR: 1.80, CI: 1.14-2.81, p: 0.012) and the disease-free survival rates were significantly associated with NLR (OR: 1.81, CI: 1.16-2.82, p: 0.009) and response to chemoradiotherapy (OR: 2.30, CI: 1.45-3.66, p: 0.001). There was no significant difference between patients with high and low NLR in terms of response to chemoradiotherapy. Similarly, there was no significant influence of the PLR. Conclusions: Pretreatment NLR and PLR measurements can provide important prognostic results in patients with NSCLC and assessment of the two parameters together appears to better predict the prognosis in patients with NSCLC. The effect of inflammation, indicators of NLR and PLR, on survival seems independent of the response to chemoradiotherapy.

• Korean Journal of Construction Engineering and Management
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• v.11 no.3
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• pp.134-144
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• 2010

In China, the enhancement of water services has become the most crucial issue confronted with the rapid urbanization and industrialization process. A huge financial gap to meet the demand for water infrastructure and need for adopting advanced operation technology precipitated the rapid growth of PPP over the last 10 years. Diverse schemes of PPP such as TOT, Divestiture, and Management Contract and Lease have been practiced. Local governments and private investors/operator have adjusted their objectives and strategies to avoid potential pitfalls behind BOT projects in China. However, current academic research outcomes do not properly reflect important issues of BOT projects or related case studies in China. This limitation has brought in the lack of assessment of important risks and success factors required for the improvement of the body of risk management. In this regard, this study uses the market analysis method to identify major schemes of PPP water projects and conducts case studies on five PPP projects to identify key risk and success factors in association with each different scheme. It is expected that the risk and success factors identified from the cases will be used as reference to Korean companies which plan to enter the Chinese water market.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.12
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• pp.485-493
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• 2017

Rearing knowledge is a significant factor of relevance for rearing practice, and assessment of rearing knowledge and practice is important for infant parents. The author adopted the Child Rearing Knowledge Scale (CRKS) and Child Rearing Practice Scale (CRPS) that were developed and validated by Saramma & Thomas. According to the international linguistic validation process, pilot testing was done based on 20 infant's mothers in one Oketani massage center and one public health center. Descriptive statistic methods and Wilcoxon Rank Sum Test were employed to evaluate the level and compare the mean score according to general characteristics of subjects of the tools. Reliability and validity were tested by Cronbach's alpha and Spearman Correlations. The mean age of the subjects was 33.94 (${\pm}2.99$) years and the mean age of babies was 3.35 (${\pm}0.58$) months. The understanding level of the Korean version of the CRKS and CRPS was 1.80 (${\pm}0.65$) and 1.33 (${\pm}0.54$), respectively. In addition, the CRKS and CRPS were relatively easy to use. The mean score of the CRKS was 22.50 (${\pm}4.89$), which was a moderate score, while the mean score of the CRPS was 30.75 (${\pm}2.04$), which was high. The Cronbach's alpha values of the CRPS were as follows: feeding, 0.71; growth and development, 0.64; cleaning and protection 0.68; infant stimulation, 0.77. There was a significant correlation between infant stimulation of the CRPS and growth and development of the CRKS (r=0.530, p=0.016). The CRKS score of medical staff was significantly higher than that of non-medical staff (p=0.04). The CRKS and CRPS are expected to be used in clinical or community care practice as easy-to-use tools that are easy to respond to.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.3
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• pp.390-398
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• 2020

To solve the problem of frequent component failure in guided weapons, a process of component failure in developed countries was investigated and analyzed. The suitability of component control, including risk assessment, analysis of operational impact, and the establishment of response measures, was also demonstrated. In addition, the economic effects of component control were presented by estimating the costs incurred if component control is performed in advance, after-sales, and non-management. DMSMS problems refer to losses or impending losses of an item, raw material, or software manufacturer or supplier. A problem with the discontinuation of parts occurs when the manufacturer or supplier ceases to produce and support the necessary parts, materials, or software, or when the supply of raw materials is no longer possible. Hence, it is important to recognize that failure to all parts of the system can occur.

• Journal of Distribution Science
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• v.13 no.10
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• pp.93-99
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• 2015

Purpose - It has been argued that the regulations restricting entry and opening hours of General Super Markets and Super Super Markets have not been as effective as expected. In contrast, the win-win item scheme that appeared recently has the advantage that it could raise the effectiveness of the system in that win-win items are in principle resigned on the basis of bilateral agreements. This study analyzes the win-win item agreement made between Homeplus at Hap-jung and small traditional markets to examine the practical effectiveness of the win-win item scheme. While existing literature studying the regulatory effects have concentrated on the restrictions around store entry or opening hours of large retailers, it can be said that there have been few empirical studies on the effect of win-win items agreement with large retailers. Research design, data, and methodology - Homeplus at Hap-jung made a win-win items agreement with nearby small traditional market traders in 2013. In accordance with this voluntary agreement, Homeplus started by limiting its sales to 15 win-win items. The survey was conducted through one-on-one interviews, April 14 to May 2, 2014, by a professional public opinion research agency. The interviews were targeted at small business retailers in the nearby traditional market. We divided the traditional markets near Homeplus at Hap-jung where the win-win item agreement was achieved into two groups, win-win item agreement markets and non win-win item agreement markets, to compare the performance difference between the two groups. Results - To determine the change in sales of the 15 win-win items, we examined the performance difference between the two groups using two criteria (compared with similar items, and compared to sales volume a year ago). The results show that the individual sales of win-win items in the win-win item agreement markets are more likely to increase than in the non win-win item agreement markets. Total sales volume of individual stores in the agreement markets also showed a more significant increase compared to a year ago than those in non win-win item agreement markets. Conclusions - Contrary to the existing retail regulations that have one-sided and uniform characteristics, it can be pointed out that the win-win item scheme has the effect of increasing the success of the system itself because it is done on the basis of mutual agreement between General Super Markets and traditional markets. The empirical results of this study can be said to support this conjecture. For the successful settlement of a win-win items agreement, the following points should be reviewed. First, it requires a great effort from the selection process of win-win items in order to improve the effectiveness of the agreement. Second, the existing General Super Markets customers should be introduced to the traditional markets or small shops to increase the sales of win-win items. Therefore, voluntary effort is essentially required from the traditional markets to engage customers.

• Journal of the Korea Organic Resources Recycling Association
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• v.13 no.4
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• pp.136-147
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• 2005

Leachate from landfill sites contains high organics, chloride and ammonium nitrogen in concentration which might be potentially major pollutants to surface and groundwater environment. Most of landfill leachate treatment plants in Korea consist of biological processes to remove BOD and nitrogen. However, the efficiencies of refractory organics removal, nitrification and denitrification have not met frequently the national effluent regulation of wastewater treatment facility, especially in winter season. Simultaneous removal of organics and nitrogen from leachate is strongly necessitated to meet the national regulation on effluents from leachate treatment facilities. The intermittently aerated biological activated carbon fluidized bed(IABACFB) process was applied to treat real landfill leachates containing refractory organics and high concentration of ammonium nitrogen. The IABACFB reactor consisted of a single bed in which BAC fluidizing and an aerating column. The fluidized bed is intermittently aerated through the blower located at the aerating column. Experiments were performed to evaluate the applicability of Intermittently Aerated BACFB for simultaneous removal of refractory organic carbon and ammonium nitrogen of leachate. Organics and ammonia nitrogen($NH{_4}{^+}-N$)are oxidized during the aerobic stage, and nitrite-nitrate nitrogen($NO{_x}{^-}-N$) are removed to nitrogen gas through denitrification reaction during anoxic state. The IABACFB reactor condition reached a steady state within 40 days since the reactors had been operated. The blowing mode of 60 min.-On/60 min.-OFF is more compatible to remove TOC and ($NH{_4}{^+}-N$) operated. The blowing mode of 60 min.-On/60 min.-OFF is more compatible to remove TOC and ($NH{_4}{^+}-N$) simultaneously than the mode of 30 min.-On/90 min.-OFF. The average removal efficiencies of TOC, the refractory organic carbon, and the average efficiencies of nitrification and denitrification were 90%, 75%, 80%, 95%, respectively.

• Science of Emotion and Sensibility
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• v.18 no.2
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• pp.19-30
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• 2015

The healing effect of the aroma treated fabrics with lavender and lemon aromas was investigated by assessing the autonomic nervous responses of human body. For this cause Lemon and lavender microcapsules were coated on a cotton fabric using a water-based acrylic binder, respectively. And the study created a total of four aroma treated fabrics at a concentration of 2% and 5% respectively. Electrocardiogram(ECG), skin conductance, and Blood flow, of ten participants were measured for 30 sec at a stable condition, at a stress status (working memory task), and at a stimulation status (after rubbing aroma treated fabrics). Subjective sensibilities of the aromas were also evaluated. With regard to the responses of the autonomic nervous system, in order to understand how the values gained after the normalization process would cause different physiological signals between the stable state and the aroma-stimulated state as well as between the stress state and the aroma-stimulated state, the study conducted a non-parametric test, friedman test as well and analyzed tendencies. LF/HF turned out to be significantly different to the stress state, and according to the results of the post-hoc comparison, lemon 5% presented statistically significant differences among the lavender 2%, lavender5%, lemon2%. Lemon 5% stimuli increased stress but stimuli consisting of the lavender 2%, the lavender 5% and the lemon 2% decreased stress because of a psychological rest. And the stimuli of the lavender 2%, the lavender 5%, the lemon 2% presented a healing effect in this research.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.12 no.2
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• pp.215-220
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• 2009

Purpose: Recently, the favorable merits of breast feeding have received widespread attention and the number of breast feeding children is increasing. We investigated the weaning practices between breast feeding infants and non-breast feeding infants with respect to iron deficiency anemia (IDA). Methods: Between March 2006 and January 2009, we surveyed 70 parents, the children of whom had been medically diagnosed with IDA, and 140 parents, the children of whom did not have IDA, about how they feed their children and how much they know about the weaning process. The infants and children were 6∼36 months of age and attended the Inha University hospital. Results: IDA patients started weaning later than non-IDA patients. Also, breast feeding in IDA patients was more frequent than in non-IDA patients (82% vs. 30%). The breast feeding group began weaning at approximately 6.4 months of age, which was statistically meaningfully compared to non-breast feeding infants. There were no differences in knowledge between the two groups of parents. Conclusion: According to our research, we assume that if weaning begins at 6 months, we cannot supply sufficient iron to meet the infant's needs, which increase sharply around 6 months of age because of depletion of stored iron. Thus, infants need to initiate weaning from breast feeding at 4 months of age to furnish an ample amount of iron or take iron-containing supplements. These methods would be expected to prevent IDA in breast feeding infants.

• Journal of the Korean School Mathematics Society
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• v.16 no.1
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• pp.1-29
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• 2013

The main goal of the research is to develop instructional consulting manual to help math teachers improve classroom teaching. Improving the quality of teaching in schools is stressed as a central focus of meaningful classroom instruction and high quality education. In this research, teaching consulting was defined as an activity that covers reflection process oriented towards formative assessment and continuing professional development. Within this context, subject-specific teaching consulting and teaching professionalism with focus on PCK was reviewed. Further, the questionnaire survey was conducted to investigate the current situation of teaching consulting and teachers' needs for consulting. And also, specific examples of subject-specific consulting based on our previous consulting experiences in math classes were shown. Alternative ways to improve subject teaching were derived through the conferences where consultants and consultees analyze video-taped lessons conducted by the consultees. By those results, a manual for invigorating teaching consulting was developed. The contents of the manual consists of setting conditions of teaching consulting and its implementation in the classroom teaching. The first part of the manual contains steps to establish teaching consulting system, the qualification and role of the consultant, system evaluation, etc. The second part of the manual presents the pre-preparation, prescription and implementation and follow-up management steps. Each part of the manual provides consultants with specific guidelines for each step. Finally, recommendations for making policy related to ways to invigorate teaching consulting was suggested. It is expected that specific examples and cases of subject-specific teaching consulting presented in this research will be used to narrow the gap between theory and practice of teaching consulting, and to help math, science and English teachers develop teaching professionalism.

• The Korean Journal of Nuclear Medicine
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• v.25 no.1
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• pp.101-109
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• 1991

To diagnosis and understand the pathophysiologic status of thyroid disease, not only hormonal measurments but also thyroid scan is believed to have a unique role. Especially in the cases of the change of the thyroid function by thyroiditis, it is emphasized that thyroid scan can be helpful in differential diagnosis. Discordant results of thyroid hormone levels and thyroid scan are found in transient hyperthyroidism, or in transient hypothyroidism. We analysed and reevaluated thyroid scan to look at the importance of thyroid scan. The results are summerised as folows: 1) 80% of hyperthyroid patients had hyperthyroidism increased RAIU with even density. they are compatible with Graves' disease. 2) 2.1% of hyperthyroid patients had normal or decreased RAIU, which are classfied as high iodine turn over genuine hyperthyroidism. 3) 8.5% of hyperthyroid patients had markedly decreased RAIU at both 2 hour and 24 hour, whose patholgic processes are suggested to be heterogenous namely subacute thyroiditis, postpartum thyroiditis, Hashimoto's thyroiditis, and painless thyroiditis. 4) 45% of hypothyroid patients had increased 24hr RAIU, 30% of hypothyroid patients were normal, 25%, decreased. In conclusion, thyroid scan should be reevaluated its useful role to asses the pathophysiologic status of thyroid disease. Especially in cases of transient thyrotoxicosis, thyroid scan is essential to diagnose and follow up the disease process.