• Title/Summary/Keyword: Probe array

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Indicator-free DNA Chip Array Using an Electrochemical System

  • Park, Yong-Sung;Kwon, Young-Soo;Park, Dae-Hee
    • KIEE International Transactions on Electrophysics and Applications
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    • v.4C no.4
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    • pp.133-136
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    • 2004
  • This research aims to develop a DNA chip array without an indicator. We fabricated a microelectrode array through photolithography technology. Several DNA probes were immobilized on an electrode. Then, target DNA was hybridized and measured electrochemically. Cyclic-voltammograms (CVs) showed a difference between the DNA probe and mismatched DNA in an anodic peak. This indicator-free DNA chip resulted in a sequence-specific detection of the target DNA.

Inspection of Welded Zone and Flat Plate Using Flexible ECA Probe (Flexible ECA Probe를 이용한 평판 및 용접부 검사)

  • Lee, Chang-Jun;Lee, Kyu Sung;Shin, Chung-Ho;Lee, Kyoung-Jun;Jang, Yoon Young
    • Journal of the Korean Society for Nondestructive Testing
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    • v.36 no.4
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    • pp.288-294
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    • 2016
  • This paper aims to compare the ability to detect notch defects existing in the plate and welded area using a flexible ECA (eddy current array) probe with OmniScan MX and MS-5800E. The characteristics of signals with various frequencies and lift-offs were also compared. As a result, when signals of frequencies 500, 1000, and 1500 kHz were used, the amplitude of the signal increased, as the depth of the notch increased, but reduced linearly in accordance with the lift-off variation. In addition, the detection sensitivity of the weld defect was found to be closely related to the contact surface of the probe and specimen. In this paper, it was demonstrated that the detection sensitivity was excellent when the contact surface of the probe and the specimen was sufficient, but it was poor when the contact surface was insufficient.

pH Measurements with a Microcantilever Array-Based Biosensor System

  • Hur, Shin;Jung, Young-Do
    • Journal of Sensor Science and Technology
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    • v.21 no.3
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    • pp.186-191
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    • 2012
  • In this paper, we present a pH measurement method that uses a microcantilever-array-based biosensor system. It is composed of microcantilever array, liquid cell, micro syringe pump, laser diode array, position sensitive detector, data acquisition device, and data processing software. Four microcantilevers are functionalized with pH-sensitive MHA(mercaptohexadecanoic acid) as a probe, while three microcantilevers are functionalized with HDT(hexadecane thiol) as reference. We prepare PBS(phosphate buffered saline) solutions of different pH and inject them into the liquid cell with a predefined volumetric speed at regular time intervals. The functionalized mircocantilevers in the liquid cell deflect as a self-assembled monolayer on the microcantilever binds with probe molecules in the solution. The difference in deflection between the MHA-covered probe microcantilever and the HDT-covered reference microcantilever was used to compensate for thermal drift. The deflection difference clearly increases with increasing pH in the solution. It was shown that when the pH values of the PBS solutions are high, there were large variations in the deflection of microcantilevers, whereas there were small variations for low pH value. The experimental results show that the microcantilever array functionalized with MHA and HDT can detect pH value with good repeatability.

Design and Array Signal Suggestion of Array Type Pulsed Eddy Current Probe for Health Monitoring of Metal Tubes (금속배관 건전성 감시를 위한 배열형 펄스와전류 탐촉자의 설계 및 배열신호 제안)

  • Shin, Young Kil
    • Journal of the Korean Society for Nondestructive Testing
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    • v.35 no.5
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    • pp.291-298
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    • 2015
  • An array type probe for monitoring metal tubes is proposed in this paper which utilizes peak value and peak time of a pulsed eddy current(PEC) signal. The probe consists of an array of encircling coils along a tube and the outside of coils is shielded by ferrite to prevent source magnetic fields from directly affecting sensor signals since it is the magnetic fields produced by eddy currents that reflect the condition of metal tubes. The positions of both exciter and sensor coils are consecutively moved automatically so that manual scanning is not necessary. At one position of send-receive coils, peak value and peak time are extracted from a sensor PEC signal and these data are accumulated for all positions to form an array type peak value signal and an array type peak time signal. Numerical simulation was performed using the backward difference method in time and the finite element method for spatial analysis. Simulation results showed that peak value increases and the peak appears earlier as the defect depth or length increases. The proposed array signals are shown to be excellent in reflecting the defect location as well as variations of defect depth and length within the array probe.

A Study of Testing Method for Diagnostic Ultrasonic Array Probe through Pattern Analysis of Acoustic-Fields with Probe Channel Division (채널별 음장분포 분석을 통한 진단용 초음파 어레이 프로브의 평가방법에 관한 연구)

  • Yoo, B.C.;Choi, H.H.;Noh, S.C.;Min, H.K.;Kwon, J.W.
    • Journal of Biomedical Engineering Research
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    • v.27 no.5
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    • pp.229-236
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    • 2006
  • The acoustic field analysis method is the superior calibration method for rectifying the ultrasonic probe sensitivity. This method also can be applied to evaluate the probe performance in clinical fields without numerical analysis and precise measurements. In this paper, we propose the method of acoustic field pattern analysis with probe channel division for the evaluation of diagnostic ultrasound probe characterization. In order to verify our purpose, we performed a set of experiments. We measured the acoustic-field pattern of the three inferiority probes by channel division to evaluate an acoustic field distribution and impulse response characteristics. By comparing the results of acoustic field measurement method with that of conventional method such as impulse response and live image test for linear array probes, it is demonstrated that the ultrasound field measurement method is more effective then conventional method in detection of defective elements.

Development of Array-based Technology for Detection of HAV Using Gold-DNA Probes

  • Wan, Zhixiang;Wang, Yefu;Li, Shawn Shun-Cheng;Duan, Lianlian;Zhai, Jianxin
    • BMB Reports
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    • v.38 no.4
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    • pp.399-406
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    • 2005
  • A sensitive method for detection of Hepatitis A virus (HAV) by utilizing gold-DNA probe on an array was developed. Amino- modified oligodeoxynucleotides at the 5' position were arrayed on an activated glass surface to function as capture probes. Sandwich hybridization occurred among capture probes, the HAV amplicon, and gold nanoparticle-supported oligonucleotide probes. After a silver enhancement step, signals were detected by a standard flatbed scanner or just by naked eyes. As little as 100 fM of HAV amplicon could be detected on the array. Therefore, the array technology is an alternative to be applied in detection of HAV due to its low-cost and high-sensitivity.

Study on Characteristics of Eddy Current Array Coil Operated in Transmit-Receive Mode and Surface Inspection Using This Probe (송수신 모드 배열 코일 와전류 탐촉자의 특성 연구 및 이를 이용한 표면검사)

  • Lee, Tae-Hun;Jee, Dong-Hyun;Cho, Chan-Hee;Kim, In-Chul
    • Journal of the Korean Society for Nondestructive Testing
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    • v.37 no.1
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    • pp.21-28
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    • 2017
  • Eddy current array (ECA) technology provides the ability to electronically scan without mechanical scanning for a footprint of probe that consists of several eddy current coils arranged side-by-side and two dimensionally. Compared to single-coil eddy current technology, the ECA technology has a higher inspection speed and reliability because a large area can be covered in a single-probe pass and the obtained images can facilitate data interpretation. In this study, we developed an eddy current array probe with $2{\times}16$ coil arrays and a multiplexer that can select transmit-receive coils sequentially and operate in transmit-receive mode. Surface inspection was performed using this probe for specimens that had various flaws and the characteristics of transmit-receive mode ECA technology was studied through an analysis of the obtained eddy current signals and C-scan images.

Two-dimensional measurements of the ELM filament using a multi-channel electrical probe array with high time resolution at the far SOL region in the KSTAR

  • Hong, Young-Hun;Kim, Kwan-Yong;Kim, Ju-Ho;Son, Soo-Hyun;Lee, Hyung-Ho;Eo, Hyun-Dong;Kim, Min-Seok;Hong, Suk-Ho;Chung, Chin-Wook
    • Nuclear Engineering and Technology
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    • v.54 no.10
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    • pp.3717-3723
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    • 2022
  • For the first time, two-dimensional temporal behavior of the edge localized mode (ELM) filament is measured in the edge tokamak plasma with a multi-channel electrical probe array (MCEP). MCEP, which has 16 floating probes (4 × 4), is mounted at the far scrape-off layer (SOL) region in the KSTAR. An electron temperature and an ion flux are measured by sideband method (SBM), which can achieve two-dimensional measurements with high time resolution. Furthermore, temporal evolutions of the electron temperature and the ion flux are obtained during the ELM occurrence. In the H-mode period, short spikes from ELM bursts are observed in measured plasma parameters, and the trend is similar to that of typical Hα signal. Interestingly, when blob-like ELM filaments crash the probe, the heat flux is significantly higher in a local region of the probe array. The results show that our probe array using the SBM can measure the ELM behavior and the plasma parameters without the effect of the stray current caused by the huge device. This study can provide valuable data needed to understand the interaction between the SOL plasma and the plasma facing components (PFCs).

Planar Array of a Probe Excited Circular Ring Radiating Bidirectional Pattern

  • Phongcharoenpanich, Chuwong;Sroysuwan, Thanarart;Wounchoum, Phairote;Kosulvit, Sompol;Krairiksh, Monai
    • Proceedings of the IEEK Conference
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    • 2002.07b
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    • pp.719-722
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    • 2002
  • This paper reports the characteristics of a bidirectional antenna by using a planar array of a probe excited circular ring. The element of a bidirectional antenna is first designed to achieve the maximum directivity. The directivity can be further increased by arranging these elements to form the linear array. There are two types of linear array to be investigated i.e., on axis and off axis arrangement. On-axis linear array yields better directivity than off-axis linear array. Therefore, this orientation is further used to form the planar array. The radiation characteristics of this optimum planar array are rigorously reported. The proposed structure is very useful to extend the distance between the base station in PCT system.

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UT Inspection Technique of Cast Stainless Steel Piping Welds Using Low Frequency TRL UT Probe (저주파수 TRL 탐촉자를 이용한 Cast Stainless Steel 배관 용접부 초음파탐상기법)

  • Shin, Keon-Cheol;Chang, Hee-Jun;Jeong, Young-Cheol;Noh, Ik-Jun;Lee, Dong-Jin
    • Transactions of the Korean Society of Pressure Vessels and Piping
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    • v.6 no.1
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    • pp.29-36
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    • 2010
  • Ultrasonic inspection of heavy walled cast austenitic stainless steel(CASS)welds is very difficult due to complex and coarse grained structure of CASS material. The large size of anisotropic grain strongly affects the propagation of ultrasound by severe attenuation, change in velocity, and scattering of ultrasonic energy. therefore, the signal patterns originated from flaws can be difficult to distinguish from scattered signals. To improve detection and sizing capability of ID connected defect for heavy walled CASS piping welds, the low frequency segmented TRL Pulse Echo and Phased Array probe has been developed. The experimental studies have been performed using CASS pipe mock-up block containing artificial reflectors(ID connected EDM notch). The automatic pulse echo and phase array technique is applied the detection and the length sizing of the ID connected artificial reflectors and the results for detection and sizing has been compared respectively. The goal of this study is to assess a newly developed ultrasonic probe to improve the detection ability and the sizing of the crack in coarse-grained CASS components.

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