• Radiation Oncology Journal
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• v.13 no.3
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• pp.205-214
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• 1995

Purpose : To investigate the effect of Ginkgo biloba extract (GBE) on hypoxic cell fraction and metabolic status in fibrosarcoma (FSa II) of C3H mouse. Materials and Methods : Fibrosarcoma (FSa II) 6 mm in diameter, growing in the right hindleg muscle of C3H mouse was used for estimation of hypoxic cell fraction using comparison of $TCD_{50}$. Radiation was given one hour after administration of GBE (100 mg/kg. i.p.) with or without priming dose of GBE (100 mg/kg, i.p.) given 24 hours earlier. Radiation was also given under air breathing condition or clamp hypoxia without GBE as controls. $^{31}p$ NMR spectroscopy was performed before and one hour after administration of GBE with or without priming dose of GBE. Results : $TCD_{50/120's}$ were 81.7 (77.7-86.0) Gy when irradiated under clamped hypoxia 69.6 (66.8-72.5) Gy under air breathing condition. 67.5 (64.1-71.1) Gy with a single dose of GBE (100 mg/kg) given one hour before irradiation, and 62.2 (59.1-65.5) Gy with two doses of GBE given at 25 hours and one hour before irradiation. The hypoxic cell fractions, estimated from $TCD_{50/120's}$, were $10.6{\%}$ under air breathing condition, $7.2{\%}$ after a single dose of GBE, and $2.7{\%}$ after two doses of GBE. The results of $^{31}P$ NMR spectroscopy were as follow. PCr/Pi ratio was $0.27{\pm}0.04$ and $0.40{\pm}0.04$ before and one hour after a single dose of GBE (p<0.05), respectively, without priming dose and $0.30{\pm}0.02$ and $0.71{\pm}0.04$, respectively, with priming dose (p<0.01). These findings indicate that the metabolic status is slightly improved after a single dose and markedly after repeated administrations. Conclusion : GBE decreases the hypoxic cell fraction and imprvoes the meta bolic status of tumor, probably by increasing the blood flow and delivery of oxygen and nutrients, resulting in increased radiosensitivity of tumor.

• Science of Emotion and Sensibility
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• v.20 no.2
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• pp.23-32
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• 2017

Although previous studies have emphasized factors affecting people's variety-seeking behavior, research has not been performed to examine the interaction effect of good-bad luck and embodied cognition (hand washing) on variety-seeking behavior. Experience of good and bad luck affects consumer information processing and hand washing is known to reverse the experience of luck. Understanding the interaction effect of good/bad luck and hand washing on variety seeking behavior will shed important light on consumer behavior including choice and product purchase. To do this, a study was performed to investigate the effects of good/bad luck priming and hand washing on variety seeking behavior. Participants were primed with good or bad luck and then were asked to either wash their hands or not. After that, they were led to choose yogurt for the next seven days and the dependent measure was the number of different tastes of yogurt participants picked up. An interaction effect of luck priming and hand washing was found. Results indicate that, in good luck condition, there was no difference in variety seeking behavior between hand washing participants and non-hand washing participants. However, in bad luck condition, hand washing participants chose less diverse tastes of yogurt than non-hand washing participants. Implications of the study findings for the field of consumer psychology and marketing are discussed.

• The Journal of the Korea Contents Association
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• v.16 no.5
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• pp.242-250
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• 2016

This study was conducted to investigate whether Stroop-related cognitive task will be affected according to the preceding affective valence factored by matchedness in response time(RT) and whether facial recognition will be indexed by specific event-related potentials(ERPs) signature in normal person as in patients suffering from affective disorder. ERPs primed by subliminal(30ms) facial stimuli were recorded when presented with four pairs of affect(positive or negative) and cognitive task(matched or mismatched) to get ERP effects(N2 and P300) in terms of its amplitude and peak latency variations. Behavioral response analysis based on RTs confirmed that subliminal affective stimuli primed the target processing in all affective condition except for the neutral stimulus. Additional results for the ERPs performed in the negative affect with mismatched condition reached significance of emotional-face specificity named N2 showing more amplitude and delayed peak latency compared to the positive counterpart. Furthermore the condition shows more positive amplitude and earlier peak latency of P300 effect denoting cognitive closure than the corresponding positive affect condition. These results are suggested to reflect that negative affect stimulus in subliminal level is automatically inhibited such that this effect had influence on accelerating detection of the affect and facilitating response allowing adequate reallocation of attentional resources. The functional and cognitive significance with these findings was implied in terms of subliminal effect and affect-related recognition modulating the cognitive tasks.

• Korean Journal of Culture and Social Issue
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• v.27 no.2
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• pp.139-165
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• 2021

In this study, we focused on the socio-structural factors that cause ageism, investigating whether the influence of the resource scarcity on ageism in the younger generation depends on socioeconomic status. To test this hypothesis, we conducted an online study of 219 adults in their 20s and 30s. Specifically, participants were randomly assigned to either the resource scarcity priming condition or the control condition, and completed a writing task. After this, participants responded to ageism and socioeconomic status items. As a result, the effect of resource scarcity on ageism was not significant. However, we found that socioeconomic status moderated the impact of resource scarcity on ageism. In other words, resource scarcity priming has been shown to significantly reduce ageism for individuals who have relatively lower socioeconomic status. This finding is in line with previous studies in which people of low socioeconomic status were found to be more sympathetic to socially disadvantaged individuals suffering deleterious situations such as resource scarcity. This work is significant in that we have looked at both the situational and personal factors influencing ageism, and in that we have attempted to examine the causal influence of resource scarcity on ageism through an experimental approach. However, since the alternative explanation of the findings has not been completely excluded, replication through further studies will be necessary.

• Korean Journal of Cognitive Science
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• v.11 no.3_4
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• pp.73-81
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• 2000

This study was conducted to investigate some characteristics of representation of category knowledge and script knowledge. Using primed lexical decision task with higher level primers in the representation structure, Experiment 1 examined the interaction effects between knowledge type and concept typicality. It was found that the concept typicality has some effects in category representation, while it has no significant effect in script representation. In Experiment 2, primers of the lower hierarchy in the representation structure were employed. The results showed that the main effect of knowledge type was significant: the response time for category knowledge was faster than that for script knowledge. Typicality effect did not show in this experiment. The results of t the two experiments suggest that category knowledge is represented in hierarchy and typicality. while script knowledge may lack in that characteristics. Other aspects of the differences in characteristics of category- and script- knowledge representation were discussed,

• Journal of Chest Surgery
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• v.22 no.6
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• pp.921-926
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• 1989

The Free fatty acid [FFA] induced massive erythrocyte crenation has been reported in patients undergoing extracorporeal circulation[EGG], suggesting that the crenated cells impair microcirculatory flow and tissue oxygenation during and after the operation. Effect of albumin administration on erythrocyte crenation was examined in 24patients undergoing open heart surgery at the department of Thoracic and Cardiovascular Surgery in the Kyung Hee University Medical Center Between January, 1989 and August, 1989: 8 patients of 24 patients [group A] were given 50 gm albumin, another 8 patients of 24 patients [group B] were g en 26 gm of albumin and the other 8 patients of 24 patients [group C] were not given any albumin as a part of the priming solution. Erythrocyte crenation was almost completely prevented in the patients given 50 gm albumin. Crenated erythrocytes d urging ECC were 3.6* 0.4 % [mean\ulcornerD] of all erythrocytes and 3.1*0.6% after ECC. This was significantly lower than in patients without albumin administration [64.2*9.5% during ECC and 28.7*1.9% after ECC]. But the effect was less striking in the patients given 25 gm albumin, 37.8* 12.0 % during ECC and 27.8*3.9 % after ECC. Maintaining an adequate level of plasma albumin is important in preventing erythrocyte crenation during ECC, improving microcirculatory flow in patients undergoing open heart surgery.

• The Journal of Korean Association of Computer Education
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• v.9 no.2
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• pp.89-99
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• 2006

This paper proposes a computational model which can simulate peculiar language phenomena observed in human lexical decision task. The model is designed to mimic major language phenomena such as frequency effect, lexical status effect, word similarity, and semantic priming effect. The experimental results show that the propose model replicated the major language phenomena and performed similar performance with that of human in LDT.

• Annual Conference on Human and Language Technology
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• 1995.10a
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• pp.244-252
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• 1995

본 연구는 한자를 이용하여 시각 정보 (Visual Information)와 음성 정보(Phonological Information)가 단어 재인과 단어 명명 과정에 어떻게 영향을 주는 지를 조사하기 위하여 실시되었다. 기존의 영어를 이용한 연구에서는 시각 정보와 음성 정보를 독립적으로 조작할 수 없었기에 두 요소가 단어 재인에 어떤 영향을 주는 지를 살피는데 어려움이 있었다. 그러나 한자단어를 이용하면 시각 정보와 음성 정보를 독립적으로 조작할 수 있기 때문에 영어 단어를 사용하는 것보다 유리하다. 본 실험에서는 한자 단어를 이용하여 점화 단어 (Prime Word)와 목표 단어(Target Word)간의 시간간격(SOA)을 100 ms, 200 ms, 750 ms, 그리고 2000 ms로 변화시키면서 시간이 흐름에 따라 시각적 유사성과 음성적 유사성에 의한 점화 효과(Priming Effect)가 어떻게 변화하는 지를 조사하였다. 이 실험 결과에 의하면, 100 ms 조건에서는 시각적 유사성에 의한 점화 효과만 있었다. 그러나, 200 ms, 750 ms, 2000 ms 조건들에서는 시각적 유사성뿐만 아니라 음성적 유사성에 의해서도 점화효과가 있었다. 이와 같은 실험 결과는 최초의 한자 단어의 어휘 접근 (Lexical Access)이 시각 정보에 의해 결정됨을 보여주고 있다.

• Proceedings of the Korean Society for Cognitive Science Conference
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• 2002.05a
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• pp.105-110
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• 2002

The syllable and the morpheme are known to be important linguistic variables. This study examined whether these variables were activated in an early stage of word recognition using the fast priming task. Mixing the lettercase for the prime, the results of experiment 1 and 2 revealed effects of the syllable and the morpheme at a short SOA (Stimulus Onset Asynchrony), but not at a long SOA. Using the same manipulation in the experiment 3 and 4, an effect of syllable was found to be significant at the short SOA, but not at the long SOA. The study showed that the syllable plays a role in an early stage of word recognition.

• Journal of Chest Surgery
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• v.26 no.10
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• pp.749-752
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• 1993

The 26 patients were randomly selected among patients who underwent valve replacement from February 1992 through September 1993 at National Medical Center. They were divided into two groups, one control group[n=13], the other aprotinin group[n=13]. The aprotinin group recieved 15000 KIU/kg aprotinin in the CPB priming volume and 35000 KIU/kg aprotinin intravenously during operation. We checked preoperative and postoperative hemoglobin, platelet, prothrombin time, activated partial thromboplastin time, creatinine phosphokinase and lactic dehydrogenase. There was no difference in the patient`s above clinical parameters between both groups. The platelet count in both groups decreaced after operation. These findings demonstrated that the effectiveness of aprotinin was not associated with platelet number but probably associated with a protection of platelet function and a prevention of hyperfibrinolysis. The intraoperative and postoperative blood loss and requirement of blood were significantly reduced in aprotinin group.