• Radiation Oncology Journal
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• v.5 no.1
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• pp.43-47
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• 1987

Primary malignant melanom of the spinal cord is extremely rare. The best treatment appears to be total surgical excision, when possible and postoperative irradiation, but the value of radiotherapy is unknown because the number of cases that have been irradiated postoperatively is small. The 2-year survival rate for primary malignant melanoma of the spinal cord is usually less than $16\%$ and most patients died within 1 year. The prognosis of this tumor is poor.

• Journal of Korean Neurosurgical Society
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• v.29 no.3
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• pp.389-395
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• 2000

Arare case of primary malignant melanoma of central nervous system in 12-month-old infant with neuro-cutaneous melanosis is presented. Primary malignant melanomas in central nervous system are very rare in children, however, it is known that leptomeningeal melanosis is malignant in 40-50% with neurocutaneous melanosis. Spinal MRI, brain CT and MRI showed diffuse intradural extramedullary mass of entire spinal cord and enhancing mass in brain stem. CSF cytology revealed abnormal cells. Biopsy from leptomeninges of posterior fossa was compatible with malignant melanoma.