• 제목/요약/키워드: Primary males

검색결과 435건 처리시간 0.028초

원발성 종격동 종양 및 낭종의 임상적 고찰 (Clinical Evaluation of the Primary Mediastinal Tumors and Cysts)

  • 이재덕;이계선
    • Journal of Chest Surgery
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    • 제29권7호
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    • pp.763-768
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    • 1996
  • 대전 을지병원 흉부외과에서는 1986년 1훨부터 1995년 4월까지 원발성 종격동종양 및 낭종으로진 단된 43명의 환자에 대해서 수술적 치료를 시행하였다. 남자환자가 19례, 여자환자가 24례였다 연령분포는 4세 부터 68세까지이고 평균연령은 31.3세였다. 가장 흔한 증상은 호흡곤란(48.8 %)이고, 그외 흉부불쾌감(39.5 %), 기침 (34.9 %), 흥통(23.3 %) 순이 었다. 가장 빈발한 종양의 위치는 전종격동이고, 후종격동, 중종격동 순이 었다. 병 리 학적으로 기형종이 가장 흔하고, 신경종, 낭종, 흉선종, 임파종 순이 었다. 가장 유용한 진단방법은 단순흉부X-선이고 최종진단은 단지 수술로써 내려졌다. 양성종양은 전례에서 완전절제 되 었고 악성종 양은 수술후 화학요법 및 방사선요법을 병용하였다. 수술후 합병증은 7례 (16.3 %)에서 있었고 술후 사망은 1 례도 없었다.

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Associations of Polymorphisms in Four Immune-related Genes with Antibody Kinetics and Body Weight in Chickens

  • Ahmed, A.S.
    • Asian-Australasian Journal of Animal Sciences
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    • 제23권8호
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    • pp.1089-1095
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    • 2010
  • Four biological candidate genes, natural resistance associated macrophage protein 1 (SLC11A1 or NRAMP), prosaposin (PSAP), interferon Gamma (IFNG), and toll-like receptor 4 (TLR4), were examined to identify single nucleotide polymorphisms (SNP) and associations of the SNP with antibody response kinetics in hens. An $F_2$ population was produced by mating $G_0$ highly inbred (<99%) males of two MHC-congenic Fayoumi lines with highly inbred Leghorn hens. The $F_2$ hens (n = 158) were injected twice with SRBC and whole, fixed Brucella abortus (BA). Blood samples were obtained before each immunization, at 7 d after primary immunization, and at several time points after secondary immunization. Minimum titers (Ymin) and the time needed to reach them (Tmin), and maximum (Ymax) titers and the time needed to reach them (Tmax), were estimated from the seven post-secondary immunization titers using a nonlinear regression model. The $F_2$ hens were genotyped for the four candidate genes by using PCR-RFLP for one SNP per gene, which identified the parental allele. General linear models were used to test associations of SNP genotypes with antibody response parameters and BW measured at 4 ages. The IFNG SNP was highly significantly (p<0.0125) associated with primary response to SRBC, Tmin to BA, Ymin to BA, and 12-week BW. The current study demonstrated that the novel IFNG promoter SNP was associated with antibody kinetics for BA and SRBC in laying hens, and also with BW, suggesting that this cytokine may play a pivotal role in the relationship between immune function and growth.

Association between the Metabolic Syndrome and High Tumor Grade and Stage of Primary Urothelial Cell Carcinoma of the Bladder

  • Ozbek, Emin;Otunctemur, Alper;Dursun, Murat;Koklu, Ismail;Sahin, Suleyman;Besiroglu, Huseyin;Erkoc, Mustafa;Danis, Eyyup;Bozkurt, Muammer
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권3호
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    • pp.1447-1451
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    • 2014
  • Purpose: To compare histopathologic findings of patients who underwent transurethral resection of a bladder tumor (TUR-B) between groups with and without the metabolic syndrome. Materials and Methods: We retrospectively analyzed data of 535 patients who underwent TUR-B in our department between October 2005 and March 2011. All patients had primary urethelial cell carcinoma (UCB). Histologic stage, grade, the presence of hypertension, diabetes mellitus, body mass index (BMI), waist circumference, HDL and trigliseride levels were evaluated. The TNM classification was used, with Ta tumor accepted as lower stage and T1 and T2 tumors as higher stage bladder cancers. Also, the pathological grading adopted by the 2004 World Health Organization grading system were applied. Non-invasive papillary urothelial neoplasms of low malignant potential were regarded as low grade. Results: Among the total of 509 patients analyzed in our study, there were 439 males (86.2%) and 70 females (13.8%). Metabolic syndrome was significantly associated with high histologic grade, and high pathologic stage (p<0.001). Conclusions: The patients with metabolic syndrome were found to have statistically significant higher T stage and grade of bladder cancer. Further studies with more patients are needed to confirm our study.

퇴행성 골관절염 환자에서 시행한 근위 경골 절골술 후 대퇴골의 회전과 임상결과의 상관관계 (Correlation between femoral rotation and clinical results after high tibial osteotomy in primary osteoarthritis patient)

  • 박상은;문상원
    • 대한정형외과스포츠의학회지
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    • 제10권2호
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    • pp.100-104
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    • 2011
  • 이 연구의 목적은 근위 경골 절골술 후 대퇴골의 회전각도와 슬관절 운동범위 및 주관적 환자 만족도 사이의 상관 관계를 분석하는 것이다. 2004년 6월부터 2008년 8월까지 고위 경골 절골술을 시행한 15명의 원발성 골 관절염 환자들이 연구 대상으로 수술 전 후 슬관절 CT를 시행하였다. 9명은 여자였으며 6명은 남자였다. 수술 전 후 슬관절의 CT를 촬영하여 대퇴골 회전 각도(TEA (Fig. 1) 및 Akagi's line (Fig. 2)으로 측정)를 백분율로 환산하여 분석하였으며 수술 후 슬관절 운동 각도와 주관적 만족도(Lysholm)의 상관관계를 확인하였다. 통계적 기법은 Kendall's 및 Spearman's nonparameter correlation coefficient 로 검정하였다. 결과상 대퇴골회전 정도와 수술 후 슬관절의 운동 각도는 의미 있는 상관 관계가 없으며 대퇴골 회전 정도와 수술후 환자의 주관적 만족도와는 의미 있는 상관 관계가 있었다. 따라서 이런 점을 알고 수술적 계획을 세운다면 보다 좋은 임상결과를 얻을 수 있을 것이다.

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Outcomes of Contralateral Bullae in Primary Spontaneous Pneumothorax

  • Noh, Dongsub;Keum, Dong yoon;Park, Chang Kwon
    • Journal of Chest Surgery
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    • 제48권6호
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    • pp.393-397
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    • 2015
  • Background: The management of contralateral bullae incidentally found in radiological studies is controversial, largely due to the unpredictability of the natural course of incidentally found contralateral bullae. This study aimed to identify the factors associated with the contralateral occurrence of primary spontaneous pneumothorax (PSP), and to characterize the outcomes of contralateral bullae incidentally found in radiological studies. Methods: From January 2005 to December 2008, 285 patients were admitted to our institution for PSP, and the patients underwent follow-up until August 2012. The relationships between the following variables and contralateral pneumothorax occurrence were evaluated: age, sex, smoking history, body mass index, ipsilateral recurrence, ipsilateral bullae size, the number of ipsilateral bullae, contralateral bullae size, and the number of contralateral bullae. Results: The study group consisted of 233 males and 29 females. The mean age and mean body index of the patients were $23.85{\pm}9.50years$ and $19.63{\pm}2.50kg/m^2$. Contralateral PSP occurred in 26 patients. The five-year contralateral PSP occurrence-free survival rate was 64.3% in patients in whom contralateral bullae were found. Conclusion: The occurrence of contralateral PSP was associated with younger age, ipsilateral recurrence, and the presence of contralateral bullae. Contralateral PSP occurrence was more common in young patients and patients with recurrent PSP. Single-stage bilateral surgery should be considered if an operation is needed in young patients, patients with recurrent pneumothorax, and patients with contralateral bullae.

원발성 폐암의 외과적 치료 (Surgical Management of Primary Lung Cancer)

  • 박경신;임승평;이영
    • Journal of Chest Surgery
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    • 제28권6호
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    • pp.591-595
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    • 1995
  • Recently, primary lung cancer has increased markedly in incidence and prevalence in Korea. From January 1986 to June 1993, 86 patients were operated and evaluated at the Department of Thoracic and Cardiovascular Surgery, Chungnam National University Hospital. The results are as follows; 1. There were 79 males and 7 females with the peak incidence of 5th and 6th decades of life[75.6% . The age ranged from 13 to 76[mean 56.6$\pm$10.3 years. 2. Symptoms were cough[47.7% , sputum[25.6% , chest pain or dyspnea[18.6% , and hemoptysis or blood tinged sputum[20.9% in order. Symptoms were frequently encountered before hospitalization, but asymtomatic patients were 12.8% in this study. 3. Methods of diagnostic confirmatiom were bronchoscopic biopsy[55.8% , percutaneous needle aspiration[29.1% , suspicious sputum cytology[1.2% , and open biopsy[14.0% . 4. Histopathologically, squamous cell carcinoma[51.2% was the most frequent cell type and adenocarcinoma[26.7% , large cell carcinoma[8.1% , adenosquamous cell carcinoma[3.5% , and the others in order. And TNM stages were Stage I 40.5%, Stage II 15.5%, Stage IIIa 27.4%, and Stage IIIb 3.6%. 5. Methods of operation were pneumonectomy[25.6% , bilobectomy[5.8% , lobectomy[53.4% , segmentectomy[1.2% , and exploration[14.0% . The overall resectability was 86.0% 6. The operative mortality was 2.3% and postoperative complications developed in 7 cases[8.1% . 7. The postoperative follow-up reveals that the overall cumulative survival rates at 1 year, 2 year, 3 year, 4 year, 5 year were 76%, 62%, 43%, 36%, and 27%, respectively.

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The Carcinogenic Liver Fluke Opisthorchis viverrini among Rural Community People in Northeast Thailand: a Cross-Sectional Descriptive Study using Multistage Sampling Technique

  • Kaewpitoon, Soraya J;Kaewpitoon, Natthawut;Rujirakul, Ratana;Ueng-arporn, Naporn;Matrakool, Likit;Tongtawee, Taweesak
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권17호
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    • pp.7803-7807
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    • 2015
  • Opisthorchis viverrini infection is a serious public health problem in Southeast Asia especially in the northeast and north of Thailand. Therefore, a cross-sectional survey using multistage sampling was conducted from the rural communities of Surin province, Thailand, during September 2013 to July 2014. O. viverrini infection was determined using Kato's thick smear technique. Socio-demographic, information resources, and history data were collected using predesigned semi-structured questionnaires. A total of 510 participants completed interviews and had stools collected. Some 32 (6.47%) participants were infected with O. viverrini. The rate was slightly higehr in males (6.61%) than females (6.32%). High frequencies were found in the age groups 61-70 (19.4%) and 71-80 years (19.4%), those involved in agriculture (10.5%), and in primary school (10.3%). The distribution of high infection was found in Tha Tum (16.7%) and Sankha district (16.7%), followed by Samrong Thap (13.3%), Si Narong (13.33%), and Buachet district (13.33%). Chi-square testing indicated that age (61-70 and 71-80 year old), education (primary school) and occupation (agriculture), were significantly associated with O. viverrini infection (p-value<0.05). Of 72.6% participants who had past histories with stool examination, 17.0% of them had been infected with O. viverrini and 43.2% treated with praziquantel. This finding confirmed that O. viverrini is still a problem in Surin province, Thailand, and therefore, interventions are urgently required for mass treatment and health education implementation.

경부 림프절 전이암의 분류 - 세침흡인 세포검사로 진단된 221예의 분석 - (Metastatic Carcinoma in Lymph Nodes of Neck - Analysis of 221 Cases Diagnosed by Fine Needle Aspiration Cytology -)

  • 김덕환;김윤주;양성은;팽성숙;장희진;손진희;서정일
    • 대한세포병리학회지
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    • 제6권1호
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    • pp.41-47
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    • 1995
  • Two hundred and twenty one consecutive patients with enlarged lymph nodes of the neck were diagnosed as metastatic carcinoma by fine needle aspiration. The metastatic carcinomas were most frequent in the supraclavicular lymph nodes (p<0.05). As a primary site, lung, stomach, upper respiratory tract and breast were commonly involved in descending order of frequency. Overall, squamous cell carcinoma was the most common in males (43%) while adenocarcinoma was the most common in females (72%) (p<0.05). While carcinomas of the esophago-gastro-intestinal tract showed a tendency to metastasize to the left supraclavicular lymph nodes, metastatic carcinomas of the lung and breast usually metastasized to the same side as that of the primary cancer with a predilection for the supraclavicular lymph nodes. The submandibular lymph nodes were frequently involved by carcinoma of the upper and lower respiratory tract, in which squamous cell carcinoma was the most prevalent cytologic type. Diagnosis by fine needle aspiration cytology is the first step in the workup of patients with nodal enlargement suspicious for malignancy, particularly in metastatic carcinoma.

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4세 이후에 구개성형술을 시행받은 환자의 발음개선 (Speech Improvement of the Patients Performed Primary Palatal Repair over 4 Years Old)

  • 강철욱;배용찬;남수봉;강영석;권순복
    • Archives of Plastic Surgery
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    • 제33권3호
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    • pp.308-312
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    • 2006
  • Time to time, we face patients who missed the proper time for primary palatal repair. Although we do not have enough available documents, it is important to establish efficacy of palatal repair in patients more than 4 years old. From May 1995 to March 2005, we selected 14 patients who underwent palatal repair in more than 4 years old patients and they are able to tolerate speech articulation tests. Out of 14 patients 5 males an 9 females in sex, aged form 4 to 50 years old. 6 patients with incomplete cleft palate and 8 patients with submucous cleft palate. Double reversing Z-plasty(n=5), pushback palatoplasty(n=4), two flap palatoplasty(n=2), von Langenbeck palatoplasty(n=2), and intravelar veloplasty(n=1) were performed. Preoperative and postoperative speech articulation test, "Simple method of speech evaluation in Korean patients with cleft palate", were conducted. Satisfaction rate was sorted into 5 levels. There is no significant statistical correlation in the speech improvement, satisfaction rate, patients sex, cleft type and operative method. But there is significant statistical correlation between the speech improvement and patienet's age. There were better result in younger patient group than aged patients group.

Opisthorchis viverrini Infection Among People in the Border Areas of Three Provinces, Northeast of Thailand

  • Kaewpitoon, Soraya J;Rujirakul, Ratana;Wakkuwattapong, Parichart;Matrakool, Likit;Tongtawee, Taweesak;Panpimanmas, Sukij;Pengsaa, Prasit;Jomkoa, Darawan;Joosiri, Apinya;Kaewpitoon, Natthawut
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권6호
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    • pp.2973-2977
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    • 2016
  • Opisthorchis viverrini is still a serious problem in Northeastern and Northern Thailand. Active surveillance is required to determine updated data for further prevention and control planning. Therefore, this study aimed to examine the prevalence and risk factors for O. viverrini in three provinces, Northeastern Thailand. A cross-sectional survey was conducted during October 2015 to March 2016 at Kaeng Sanam Nang district of Nakhon Ratchasima province, Waeng Noi district of Khon Kaen province, and Khon Sawan district of Chaiyaphum province, Thailand. Stool samples were examined by using a modified Kato-Katz Thick smear technique. From a total of 978 participants screened, O. viverrini infection was found in 1.74%, the majority opf positive cases being male (6.62%), age group 51-60 years old (4.21%), educated at primary school (8.43%), occupied with agriculture (9.62%),having an income <4,000 baht per month (4.82%), and living in Khon Sawan district (8.43%). Participants had a high knowledge level (42.43%), good attitude level (34.76%), and fair level (38.04%). The present study indicates the O. viverrini infection rate is low, but elderly males with primary school education involved in agriculture are still frequently effected particularly in Khon Sawan district. Therefore, this risk group requires behavior modification and continued monitoring.