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Oral Exposure Assessment of N-Nitrosamines from Rubber Balloons in Korea (고무풍선 중 니트로스아민류의 노출평가 연구)

  • Hyunkyung Kim;Kiyoung Lee
    • Journal of Environmental Health Sciences
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    • v.49 no.4
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    • pp.210-217
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    • 2023
  • Background: N-nitrosamines are carcinogenic substances often found in rubber products. They are produced when certain additives of rubber products react with nitrite in saliva or air. Exposure assessment for the proper management and communication of N-nitrosamines in rubber balloons should be carried out. Objectives: This study was conducted to determine the concentrations of N-nitrosamines in rubber balloons in the South Korean market and assess exposure among Korean children. Methods: Forty eight rubber balloon products in the domestic market were purchased and a total of 68 balloons were analyzed for N-nitrosamines and N-nitrosatable substances. Chemical analysis was conducted by HPLC-MS/MS according to the method EN 71-12. For exposure assessment, an exposure algorithm and coefficients were obtained from previous studies. Results: Among the 68 rubber balloons, N-nitrosamines were detected in 18 (26.5%) with an average level of 60.77 ㎍/kg. N-Nitrosatable substances were detected in 44 products (64.7%) with an average level of 1353.33 ㎍/kg. As a result of the exposure evaluation, the exposure dose differed according to how exposure coefficients were applied. The median exposure (50th percentile) was higher in the age group of 6~12 years, and high exposure (95th percentile) was higher in the age group of 13~18. Conclusions: We evaluated the N-nitrosamines contained in rubber balloons purchased in the domestic market and assessed oral exposure among South Korean children. For integrated risk management of N-nitrosamines, further studies and discussion regarding exposure and risk assessment are required.

Fractal dimension analysis as an easy computational approach to improve breast cancer histopathological diagnosis

  • Lucas Glaucio da Silva;Waleska Rayanne Sizinia da Silva Monteiro;Tiago Medeiros de Aguiar Moreira;Maria Aparecida Esteves Rabelo;Emílio Augusto Campos Pereira de Assis;Gustavo Torres de Souza
    • Applied Microscopy
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    • v.51
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    • pp.6.1-6.9
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    • 2021
  • Histopathology is a well-established standard diagnosis employed for the majority of malignancies, including breast cancer. Nevertheless, despite training and standardization, it is considered operator-dependent and errors are still a concern. Fractal dimension analysis is a computational image processing technique that allows assessing the degree of complexity in patterns. We aimed here at providing a robust and easily attainable method for introducing computer-assisted techniques to histopathology laboratories. Slides from two databases were used: A) Breast Cancer Histopathological; and B) Grand Challenge on Breast Cancer Histology. Set A contained 2480 images from 24 patients with benign alterations, and 5429 images from 58 patients with breast cancer. Set B comprised 100 images of each type: normal tissue, benign alterations, in situ carcinoma, and invasive carcinoma. All images were analyzed with the FracLac algorithm in the ImageJ computational environment to yield the box count fractal dimension (Db) results. Images on set A on 40x magnification were statistically different (p = 0.0003), whereas images on 400x did not present differences in their means. On set B, the mean Db values presented promising statistical differences when comparing. Normal and/or benign images to in situ and/or invasive carcinoma (all p < 0.0001). Interestingly, there was no difference when comparing normal tissue to benign alterations. These data corroborate with previous work in which fractal analysis allowed differentiating malignancies. Computer-aided diagnosis algorithms may beneficiate from using Db data; specific Db cut-off values may yield ~ 99% specificity in diagnosing breast cancer. Furthermore, the fact that it allows assessing tissue complexity, this tool may be used to understand the progression of the histological alterations in cancer.

HSE Block : Automatic Optimization of the Number of Convolutional Layer Filters using SE Block (HSE Block : SE Block을 활용한 합성곱 신경망 필터 수 자동 최적화)

  • Tae-Wook Kim;Hyeon-Jin Jung;Ellen J. Hong
    • Journal of the Institute of Convergence Signal Processing
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    • v.23 no.3
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    • pp.179-184
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    • 2022
  • In this paper, we are going to study how we can automatically determine the number of convolutional filters for the optimal model without a search algorithm. This paper proposes HSE Block by connecting SE Block proposed in SENet to a convolutional neural network and connecting a convolutional neural network not learned at the bottom. An experiment was conducted to increase the number of filters by one per 3 epoch using two datasets for the HSEBlock model and to increase the number of filters by the value in the filter. Based on this experiment, the model was constructed with multi-layer HSE Block instead of layer HSE Block, and the experiment was carried out using a dataset that was more difficult to learn than the one used in the previous experiment. The effect of HSE Block was verified by conducting an experiment with the number of HSE Blocks set to 2, 3, 4, and 5 on a dataset that is more difficult to learn than before.

Meta-Record Algorithm based on Mnemonic System in Mobile Environments (모바일 환경에서 기억법 기반 메타 레코드 알고리즘)

  • Boon-Hee Kim
    • The Journal of the Korea institute of electronic communication sciences
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    • v.18 no.2
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    • pp.305-312
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    • 2023
  • In introducing memory methods in various educational fields, programs in a mobile environment can be used for the purpose of increasing accessibility and enhancing the effectiveness of education. It is much easier to remember words with meaning than to remember numerical information such as years. From the standpoint of increasing the educational effect, the part that needs to be supplemented with the help of the application can be said to be numerical information. Most studies related to conventional numerical memory have focused on the form that helps memory by imaging numbers. In the paper on memory-based meta-record algorithms in the mobile environment, the application developed in the previous study attempts to supplement this by discovering and simply modifying the user's mistakes in the entered numerical information. In this study, we aim to increase the memory rate by constructing metadata based on personalized log information and correcting mistakes. To do this, applications suitable for the mobile environment are developed, a structure of meta-record data is proposed, and meta-record application algorithms are implemented and evaluated.

Classification of Torso Shapes of Men Aged 40-64 - Based on Measurements Extracted from the 8th Size Korea Scans - (40-64세 남성의 토르소 형태 분류에 관한 연구 - 제8차 Size Korea 인체형상으로부터 추출한 측정값을 이용하여 -)

  • Guo Tingyu;Eun Joo Ryu;Hwa Kyung Song
    • Fashion & Textile Research Journal
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    • v.25 no.1
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    • pp.92-103
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    • 2023
  • As the body shape change which occurs after middle age is the main factor affecting the fit of ready-to-wear clothes, this study was designed to classify and analyze the torso shapes of middle-aged men. This study sorted 3D body scans of 200 men aged 40-64 from the 8th Size Korea (2021) database and extracted their 47 measurement values using the Grasshopper algorithm for automatic extraction landmarks and measurements, developed by the previous research (Ryu & Song, 2022). Eight principal components (torso length, shoulder size, overall body size, abdomen prominence, back protrusion, neck inclination, upper body slope, and hip prominence) were identified and four torso shapes were classified. Shape 1 (28.5%) exhibited the shortest torso length, the narrowest shoulders, and the most protruding back. Shape 2 (21.0%) exhibited the skinniest body and the largest backward inclination of the upper body. Hence, the back appeared to be protruding, and the abdomen looked prominent. Shape 3 (25.5%) had the largest overall body size. Thus, the abdomen looked the least protruding, and it exhibited the flattest back. Shape 4 (25.0%) had the longest torso, widest shoulders, straightest neck, and the least protruding hips. This study suggested these three discriminant functions to identify a new person's torso type.

Study on Potential Topics of the MyData and Data Transactions Using LDA Topic Modeling (국내 마이데이터 태동과 데이터 거래에 관한 잠재적 주제 분석)

  • Cho, Ji Yeon;Lee, Bong Gyou
    • Journal of Digital Convergence
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    • v.20 no.3
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    • pp.221-229
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    • 2022
  • With the recent full-fledged MyData service, interest in the use of personal data is increasing. However, studies on MyData are still in the early stages, focusing on legal and institutional discussions, and studies from a comprehensive perspective are insufficient. Therefore, this study aimed at finding the potential topics formed by social discussions by analyzing news data from 2018 to the present. News data analysis using LDA topic modeling were conducted and 6 potential topics including digital transformation in finance, scope of Mydata business license, amendments and data-related laws, safe use of big data, data economy promotion policy and strategy of the financial industry were derived. This study has significance in that it comprehensively viewed the issues that emerged with the MyData and deriving gaps in previous discussion. Future research is expected to identify changes after the launch of MyData service and provide specific implications through research by specific industries.

Method for eliminating source depth ambiguity using channel impulse response patterns (채널 임펄스 응답 패턴을 이용한 음원 깊이 추정 모호성 제거 기법)

  • Cho, Seongil
    • The Journal of the Acoustical Society of Korea
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    • v.41 no.2
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    • pp.210-217
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    • 2022
  • Passive source depth estimation has been studied for decades since the source depth can be used for target classification, target tracking, etc. The purpose of this paper is to solve the problem of ambiguity in the previous paper [S.-il. Cho et al. (in Korean), J. Acoust. Soc. Kr. 38, 120-127 (2019)] that source depth is estimated in two points. The patterns of phase shift of Channel Impulse Response(CIR) reflected in ocean surface and bottom is used for removing ambiguity of the source depth estimation, and after removing ambiguity, source depth is estimated at one point through the intersection of CIR. In order to extract CIR in case of unknown source signal and continuous signal or noise, Ray-based blind deconvolution is used. The proposed algorithm is demonstrated through numerical simulation in ocean waveguide.

Machine Learning Model for Recommending Products and Estimating Sales Prices of Reverse Direct Purchase (역직구 상품 추천 및 판매가 추정을 위한 머신러닝 모델)

  • Kyu Ik Kim;Berdibayev Yergali;Soo Hyung Kim;Jin Suk Kim
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.46 no.2
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    • pp.176-182
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    • 2023
  • With about 80% of the global economy expected to shift to the global market by 2030, exports of reverse direct purchase products, in which foreign consumers purchase products from online shopping malls in Korea, are growing 55% annually. As of 2021, sales of reverse direct purchases in South Korea increased 50.6% from the previous year, surpassing 40 million. In order for domestic SMEs(Small and medium sized enterprises) to enter overseas markets, it is important to come up with export strategies based on various market analysis information, but for domestic small and medium-sized sellers, entry barriers are high, such as lack of information on overseas markets and difficulty in selecting local preferred products and determining competitive sales prices. This study develops an AI-based product recommendation and sales price estimation model to collect and analyze global shopping malls and product trends to provide marketing information that presents promising and appropriate product sales prices to small and medium-sized sellers who have difficulty collecting global market information. The product recommendation model is based on the LTR (Learning To Rank) methodology. As a result of comparing performance with nDCG, the Pair-wise-based XGBoost-LambdaMART Model was measured to be excellent. The sales price estimation model uses a regression algorithm. According to the R-Squared value, the Light Gradient Boosting Machine performs best in this model.

Identification of Multiple Cancer Cell Lines from Microscopic Images via Deep Learning (심층 학습을 통한 암세포 광학영상 식별기법)

  • Park, Jinhyung;Choe, Se-woon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2021.05a
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    • pp.374-376
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    • 2021
  • For the diagnosis of cancer-related diseases in clinical practice, pathological examination using biopsy is essential after basic diagnosis using imaging equipment. In order to proceed with such a biopsy, the assistance of an oncologist, clinical pathologist, etc. with specialized knowledge and the minimum required time are essential for confirmation. In recent years, research related to the establishment of a system capable of automatic classification of cancer cells using artificial intelligence is being actively conducted. However, previous studies show limitations in the type and accuracy of cells based on a limited algorithm. In this study, we propose a method to identify a total of 4 cancer cells through a convolutional neural network, a kind of deep learning. The optical images obtained through cell culture were learned through EfficientNet after performing pre-processing such as identification of the location of cells and image segmentation using OpenCV. The model used various hyper parameters based on EfficientNet, and trained InceptionV3 to compare and analyze the performance. As a result, cells were classified with a high accuracy of 96.8%, and this analysis method is expected to be helpful in confirming cancer.

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Spatial Estimation of soil roughness and moisture from Sentinel-1 backscatter over Yanco sites: Artificial Neural Network, and Fractal

  • Lee, Ju Hyoung
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.125-125
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    • 2020
  • European Space Agency's Sentinel-1 has an improved spatial and temporal resolution, as compared to previous satellite data such as Envisat Advanced SAR (ASAR) or Advanced Scatterometer (ASCAT). Thus, the assumption used for low-resolution retrieval algorithms used by ENVISAT ASAR or ASCAT is not applicable to Sentinel-1, because a higher degree of land surface heterogeneity should be considered for retrieval. The assumption of homogeneity over land surface is not valid any more. In this study, considering that soil roughness is one of the key parameters sensitive to soil moisture retrievals, various approaches are discussed. First, soil roughness is spatially inverted from Sentinel-1 backscattering over Yanco sites in Australia. Based upon this, Artificial Neural Networks data (feedforward multiplayer perception, MLP, Levenberg-Marquadt algorithm) are compared with Fractal approach (brownian fractal, Hurst exponent of 0.5). When using ANNs, training data are achieved from theoretical forward scattering models, Integral Equation Model (IEM). and Sentinel-1 measurements. The network is trained by 20 neurons and one hidden layer, and one input layer. On the other hand, fractal surface roughness is generated by fitting 1D power spectrum model with roughness spectra. Fractal roughness profile is produced by a stochastic process describing probability between two points, and Hurst exponent, as well as rms heights (a standard deviation of surface height). Main interest of this study is to estimate a spatial variability of roughness without the need of local measurements. This non-local approach is significant, because we operationally have to be independent from local stations, due to its few spatial coverage at the global level. More fundamentally, SAR roughness is much different from local measurements, Remote sensing data are influenced by incidence angle, large scale topography, or a mixing regime of sensors, although probe deployed in the field indicate point data. Finally, demerit and merit of these approaches will be discussed.

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