• Title/Summary/Keyword: Prevention model

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MTHFR C677T Polymorphism and Pancreatic Cancer Risk: a Meta-analysis

  • Liu, Xiang-Ming;Liu, Feng-Hua;Tang, Yong;Li, Qiang
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3763-3766
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    • 2012
  • Background: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the metabolism of folate, and the role of the MTHFR C677T polymorphism in pancreatic carcinogenesis is still controversial. Methods: A literature search was performed using Pubmed and CNKI databases for published studies through May 2012. We performed a meta-analysis of all relevant case-control studies that examined the association between MTHFR C677T polymorphism and pancreatic cancer risk. Results: Finally, 9 individual case-control studies with a total of 1,299 pancreatic cancer cases and 2,473 controls were included into this meta-analysis. Results: This metaanalysis showed there was an obvious association between MTHFR C677T polymorphism and pancreatic cancer risk in East Asians (for allele model, OR = 1.67, 95%CI 1.11-2.51; For homozygote model, OR = 2.77, 95%CI 1.40-5.48; for recessive model, OR = 1.96, 95%CI 1.54-2.50; for dominant model, OR = 2.11, 95%CI 1.01-4.41). However, no significant association was found in Caucasians. Conclusions: The MTHFR C677T polymorphism is associated with pancreatic cancer risk, and a race-specific effect may exist in this association. More studies with a larger sample size are needed to further clarify this association.

Numerical simulation on gas continuous emission from face during roadway excavation

  • Chen, Liang;Wang, Enyuan;Feng, Junjun;Li, Xuelong;Kong, Xiangguo;Zhang, Zhibo
    • Geomechanics and Engineering
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    • v.10 no.3
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    • pp.297-314
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    • 2016
  • With the mining depth continuously increasing, gas emission behaviors become more and more complex. Gas emission is an important basis for choosing the method of gas drainage, gas controlling. Thus, the accurate prediction of gas emission is of great significance for coal mine. In this work, based on the sources of gas emission from the heading faces and the fluid-solid coupling process, we established a gas continuous dynamic emission model, numerically simulated and applied it to the engineering. The result was roughly consistent with the actual situation and shows the model is correct. We proposed the measures of reducing the excavation distance and borehole gas drainage based on the model. The measures were applied and the result shows the overproof problem of gas emission disappears. The model considered the influence factors of gas emission wholly, and has a wide applicability, promotional value. The research is of great significance for the controlling of gas disaster, gas drainage and pre-warning coal and gas outbursts based on gas emission anomaly at the heading face.

Case Study for Efficiency of Counter-Debrisflow Structures in Baekyang Mt. (토석류 방재구조물 성능 검토 수치해석 - Case study: 부산 백양산)

  • Jeong, Seokil;Song, Chag Geun;Kim, Hong Taek;Lee, Seung Oh
    • Journal of the Korean Society of Safety
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    • v.33 no.4
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    • pp.84-89
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    • 2018
  • The number of landslides has increased since the 2000s due to the increased frequency of heavy rainfall caused by abnormal weather. A variety of debris flow prevention facilities have been installed as a countermeasure against this problem. However, it is not easy to evaluate the efficiency of debris flow prevention structures except for the structures with constant volume such as the erosion dam, because the other structures are limited to be reproduced in simulation program for debris flow. Therefore, the methods by which the debris flow prevention structures were modeled were proposed, and the efficiency of four prevention structures installed in Baekyang Mt. in Busan was evaluated with UDS, which accuracy had been verified, using these methods. The initial amount of debris flow was determined based on landslide which occurred in 2014, and specifications of the complex retaining walls around the settlements were measured and applied modeling for terrain. The numerical results showed that the efficiency of debris flow prevention structures could be quantitatively presented. Among the debris flow prevention structures installed in Baekyang Mt., prevention structure of barrier type for debris flow was the most efficiency and debris flow prevention device was the lowest efficiency when the only depth of debris was evaluated. It seems that this study is meaningful to propose the methods which were used to model the debris flow prevention structures that could not be reproduced in most 2D debris flow numerical analysis programs. If precise verification of the presented methods is carried out, it will be possible to provide clear criteria for the efficiency evaluation method of disaster prevention structures.

Factors influencing fall prevention nursing performance of hospital nurses (병원간호사의 낙상예방간호 수행 영향요인)

  • Jang, Keong-Sook;Kim, Hae-Sook
    • The Korean Journal of Emergency Medical Services
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    • v.20 no.3
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    • pp.69-83
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    • 2016
  • Purpose: The purpose of this study was to explore the factors influencing evidence-based fall prevention nursing performance of hospital nurses. Methods: A self-reported questionnaire was completed by 344 nurses from three general hospitals from January 20 to March 10, 2013. The study instruments included general characteristics of the subjects, and awareness and performance of fall prevention. Data were analyzed by t test, ANOVA, Pearson's correlation, and multiple regression using SPSS v. 20.0. Results: There were statistically significant differences in awareness and performance according to age, marital status, clinical experiences, workplace, experience of fall prevention education, knowledge of fall prevention, compliance with fall prevention, attention level toward prevention, recognition level of potential falls, nurse responsibility for falls, importance of fall prevention, efforts level for fall prevention, and awareness score of falls prevention. There was a positive correlation among awareness and performance of fall prevention. Based on the multiple regression analysis, compliance with fall prevention, efforts level for fall prevention, and awareness score of falls prevention were significant predictors for performance of fall prevention. The explanation power of the model was 64.1%. Conclusion: The findings revealed the need to develop an effective nursing intervention to improve hospital nurses' performance for fall prevention.

The Effects of COVID-19 Knowledge and COVID-19 Health Beliefs on Infection Prevention Behaviors in Elementary and Middle School Students (초·중등학교 청소년의 COVID-19 지식, COVID-19 건강신념이 감염예방행위에 미치는 영향요인)

  • Gyehyun Jung;Jin Hee Park;Hye Young Song
    • Journal of the Korean Society of School Health
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    • v.37 no.1
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    • pp.1-11
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    • 2024
  • Purpose: The purpose of the study was to conduct a descriptive survey to examine the knowledge, infection prevention behaviors, and health beliefs regarding COVID-19 and to identify factors that influence infection prevention behaviors in elementary and middle school students based on the Health Belief Model. Methods: The study included 388 elementary and middle school students in Seoul, Gyeonggi, and Jeonbuk provinces. Data were collected from September 1 to September 15, 2023. The questionnaire consisted of 10 questions about COVID-19 knowledge, 13 questions about infection prevention behaviors, and 15 questions about health beliefs. The collected data were subjected to multiple hierarchical regression analyses. The cronbach's α of infection prevention behaviors was 0.83, the KR-20 of COVID-19 related knowledge was 0.68, and the Cronbach's α of COVID-19 related health beliefs was 0. 78. Results: In Model 1, females showed higher levels of infection prevention behaviors than males (β=.14, p=.006) and middle school students showed lower levels of infection prevention behaviors than elementary school students (β=-.10, p=.037). In Model 2, among COVID-19-related health beliefs, barriers had a significant negative effect on infection prevention behaviors (β=-.20, p<.001) and cues to action had a significant positive effect on infection prevention behaviors (β=.14, p=.037), indicating that lower barriers and higher cues to action were associated with higher levels of infection prevention behaviors. Conclusion: The results showed that prevention behaviors were associated with lower barriers and higher cues to action among COVID-19 health beliefs. Elementary and middle school students in Korea spend a lot of time in groups at private academies or school, which are closed spaces with poor ventilation, making them vulnerable to new infectious diseases such as COVID-19. Unlike adults, infectious diseases can have serious impact on their mental and social health. Therefore, it is necessary for schools to provide accurate and timely health education about COVID-19 to increase cues to action for elementary and middle school students in order to improve their infection prevention behaviors.

An Appropriate Parent Role Model for Alcohol, Tobacco and Other Drug Abuse Prevention in Adolescence (청소년의 술, 담배, 기타 약물남용 예방을 위한 적극적인 부모역할 모델)

  • Burm, Jin Bil
    • Korean Journal of Clinical Pharmacy
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    • v.13 no.1
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    • pp.18-28
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    • 2003
  • An appropriate parent role model for alcohol, tobacco and other drug abuse prevention in adolescence was designed as part of a comprehensive effort to reduce the use of alcohol, tobacco and other drugs by underage youth. The content of the model offers a new and positive chemical health model. The model calls for development of a set of guidelines that can provide the framework for examining alcohol, tobacco and other drug use. The actions of adults in the community, especially parents, are very important factors in whether or not youth use chemicals. So these guidelines can be used to assist parents and other adults with questions such as, what can we say to young people about using alcohol, tobacco or other drugs except that it's against the law? At what age and times are discussions appropriate? What can we do to make our community a healthier place in which young people can make better decisions about alcohol, tobacco and other drug use? The model acknowledges and affirms the legal and appropriate use of alcohol and other drugs as well as supports the decision not to drink. It encourages participants to consider their own guidelines for using and not using alcohol and other drugs. The guidelines can also be used as the basis for early intervention when use is illegal, unhealthy or risky. It is important to note that the model affirms healthy and appropriate use as well as nonuse.

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A Framework for developing the automated management system of environmental complaints in construction projects

  • Hong, Juwon;Kang, Hyuna;Hong, Taehoon;An, Jongbaek;Jung, Seunghoon
    • International conference on construction engineering and project management
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    • 2020.12a
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    • pp.417-422
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    • 2020
  • Vast quantities of environmental pollutants from construction projects are causing significant damage to nearby local communities and thus generate environmental complaints. The construction company, responsible for compensating and resolving environmental complaints, suffers economic damages due to additional expenditures and schedule delays in construction projects. Meanwhile, the construction industry can stagnate from a broader perspective. Therefore, this study aimed to propose a framework for developing an automated management system which consists of two models for environmental complaints in construction projects: (i) the prediction model: a model for predicting environmental complaints based on factors related to environmental complaints; and (ii) the prevention model: a model for providing construction companies with the optimal prevention measure to effectively prevent environmental complaints according to the results of the prediction model. In addition, the algorithm for integrating the developed models into the management system in construction projects was proposed. Eventually, the application of the management system to construction projects can ensure the profitability of construction companies and mitigate damage from environmental pollutants to the nearby local community.

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Model-Based Survival Estimates of Female Breast Cancer Data

  • Khan, Hafiz Mohammad Rafiqullah;Saxena, Anshul;Gabbidon, Kemesha;Rana, Sagar;Ahmed, Nasar Uddin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2893-2900
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    • 2014
  • Background: Statistical methods are very important to precisely measure breast cancer patient survival times for healthcare management. Previous studies considered basic statistics to measure survival times without incorporating statistical modeling strategies. The objective of this study was to develop a data-based statistical probability model from the female breast cancer patients' survival times by using the Bayesian approach to predict future inferences of survival times. Materials and Methods: A random sample of 500 female patients was selected from the Surveillance Epidemiology and End Results cancer registry database. For goodness of fit, the standard model building criteria were used. The Bayesian approach is used to obtain the predictive survival times from the data-based Exponentiated Exponential Model. Markov Chain Monte Carlo method was used to obtain the summary results for predictive inference. Results: The highest number of female breast cancer patients was found in California and the lowest in New Mexico. The majority of them were married. The mean (SD) age at diagnosis (in years) was 60.92 (14.92). The mean (SD) survival time (in months) for female patients was 90.33 (83.10). The Exponentiated Exponential Model found better fits for the female survival times compared to the Exponentiated Weibull Model. The Bayesian method is used to obtain predictive inference for future survival times. Conclusions: The findings with the proposed modeling strategy will assist healthcare researchers and providers to precisely predict future survival estimates as the recent growing challenges of analyzing healthcare data have created new demand for model-based survival estimates. The application of Bayesian will produce precise estimates of future survival times.

Village Voices: Lessons about Processes for Disease Prevention from a Qualitative Study of Family Health Leaders in a Community in Northeastern Thailand

  • Jongudomkarn, D;Singhawara, P;Macduff, C
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.10
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    • pp.4401-4408
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    • 2015
  • Background: Cancer is a primary source of concern in Thailand and other countries around the world, including the Asian-Pacific region. Evidence supports that an important contributing cause of cancer and other chronic illnesses such as stroke, diabetes, and hypertension is excessive alcohol consumption. Studies conducted in Thailand reveal a worrisome rise in the number of new and regular drinkers in communities. Therefore, actions for primary, secondary and tertiary prevention of problem drinking are necessary. In recent years nurses in North East Thailand have been developing and implementing the Khon Kaen Family Health Nursing model to embed disease prevention in communities through the actions of family health nurses and local family health leaders. Aim: The aim of this qualitative research was to better understand the experiences of the local family health leaders using this model and to synthesize lessons learned. Materials and Methods: As part of a participatory action research approach involving analysis of focus group discussions and individual interviews, the experiences of 45 family health leaders were synthesized. Results: Four main themes were identified, namely: i) Family first: role modeling beginning at the personal and family level. ii) Local leverage: using village community forums to reduce alcohol drinking. iii) Gentle growth: making the first step and treading gently; and iv) Respect, Redemption, Rehabilitation: valuing the person to re-integrate them in the village society. Conclusions: As alcohol consumption in the village declined significantly following the prevention program, these findings illuminate how low-tech integrated prevention approaches may be very useful, particularly in rural communities. The lessons learned may have relevance not only in Thailand but in other countries seeking to prevent and mitigate behavior that conduces to diseases such as cancer.