• Journal of Nutrition and Health
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• 제28권5호
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• pp.406-414
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• 1995

Nitrogen(N) concentration of preterm(PT) and term (T) milk in various fractions, such as total, protein, nonprotein, whey protein and casein were determined at 2-5 days, 1, 2, 4 and 6 weeks of postpartum. The purpose of this study was to investigate the nitrogen concentration of human milk from mothers delivering at preterm and term, and the propriety of preterm milk for premature infants. The concentration of total N, nonprotein N, protein N, whey protein N and casein N in preterm milk was decreased significantly with time postpartum. Total N was 374mg/이 at colostrum, 232mg/dl at mature milk. Whey protein N was decreased from 42mg/dl at 2-5 days to 32mg/dl at 4-6 weeks. Protein N was 332mg/dl at colostrum, 202mg/dl at mature milk. The proportion of whey protein N and casein N were 39:61 at colostrum, 28:72 at mature milk. No difference were found between T and PT milk for total nitrogen excepted 2 weeks. In this report we show that nitrogen concentration except casetpt casein N is smaller in milk from mothers giving birth prematurely than in milk from mothers giving birth at term, over the first two weeks of lactationl But protein N was higher in preterm milk than term milk, whey protein nitrogen was lower. By comparing predicted nitrogen intakes to estimated requirements of preterm infants fed 150 to 200ml/kg/day of their own mother's milk, we predict that the quantities of protein provided would be adequate to meet the requirements of the prematured infants during the early weeks of life.

• Neonatal Medicine
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• 제16권2호
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• pp.121-130
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• 2009

Over the past 20 years, neonatal mortality rates for preterm infants, particularly those born extremely preterm and with a very low birth weight, have decreased steadily. As more very immature preterm infants survive, provision of enteral feeding has become a major focus of concern. According to many experts on neonatal nutrition, the goal for the nutrition of preterm infants should be to achieve a postnatal growth rate approximating that of a normal fetus of the same gestational age. Total parenteral nutrition for maintaining nutritional integrity is mandatory before successful transition to enteral feeding. Early initiation of trophic enteral feeding is vital for postnatal adaptation. Recently published randomized controlled trials provide no evidence to support the practice of postponing enteral feeding to reduce the incidence of necrotizing enterocolitis. Early trophic feeding yields demonstrable benefits and there is currently no evidence of any adverse effects following early feeding. Preterm milk from the infant's own mother is the milk of choice, which can always be supplemented with a human milk fortifier. Here we review over 50 randomized controlled trials and over seven systematic reviews published on neonatal parenteral and enteral feeding of preterm infants. Neonatologists must make use of the evidence from these studies as a reference for feeding protocols for preterm infants in their NICUs are to be based.

• 대한한방부인과학회지
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• 제25권2호
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• pp.200-206
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• 2012

Objectives: The purpose of this study is to report the effect of combination of herbal medicine and conventional treatment on preterm labor patient at high risk for preterm delivery. Methods: The patient in this case was 33-year-old female with gravid 3, para 2, abortus 1. She experienced 1 preterm birth 5 years ago. She visited our clinic with lower abdominal pain at 14th gestational week. We treated her by herbal medicine. She also take vaginal progesterone from 19th gestational week to 34th gestational week. Results: She maintained her pregnancy until giving a birth by cesarean section at 38th gestational week. No adverse effects were not observed among mother or infant. Conclusions: Combination of herbal medicine and conventional treatment is effective on preterm labor patient at high risk for preterm delivery.

• 대한간호학회지
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• 제42권2호
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• pp.181-189
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• 2012

Purpose: This study was done to compare breast feeding rates and factors influencing feeding practice between late preterm ($34{\leq}GA<37$) and preterm infants (GA<34). Methods: A survey was done of 207 late preterm and 117 preterm infants in neonatal intensive care units (NICU) of 4 university hospitals in D city. Data were collected from July 2009 to June 2010 from 324 medical records in the NICU. Breast-feeding at home was checked either by telephone survey or questioning during hospital visits. Results: Rate of breast feeding for late preterm infants was significantly lower than for preterm infants. There was no significant difference in breast-feeding at home. We found differences in factors influencing breast feeding between the two groups. Factors influencing feeding for late preterm infants were type of delivery, mothers' occupation, feeding type during hospitalization, time elapse from hospital discharge, total admission days, infant's body weight at first feeding and length of NPO (nothing by mouth). Factors influencing feeding for preterm infants were birth order, maternal disease and obstetric complications, and one-minute Apgar score. Conclusion: Results of the study show low rates of breast-feeding for late preterm infants indicating a need for breast-feeding education for mothers of these infants.

• Journal of Nutrition and Health
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• 제28권2호
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• pp.137-143
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• 1995

In this study, lipid composition of milk obtained in colostrum from 22 mothers delivering preterm infants and 17 mothers delivering term infants was analyzed. Fatty acid composition and vitamin E content were analyzed as well as the concentrations of total lipids in preterm and fullterm milk. Lipid and cholestol concentrations were higher in the fulltrm milk than preterm milk. PUFA and P/S ratio in preterm milk were higher than those in fullterm milk. On the other hand, SFA and MUFA contents were higher in the fullterm milk. Vitamin E which is related to PUFA concentration in colostrum was also higher in the preterm milk than fullterm milk.

• 여성건강간호학회지
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• 제15권2호
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• pp.140-149
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• 2009

Purpose: The purposes of this phenomenological study were to explore the experience of preterm labor. Methods: The participants were 7 women admitted to two obstetric hospitals in Kyunggi-do Province with preterm labor. Data was collected with MP3 records through individual in-depth interviews and participated observation. The data was analyzed by Giorgi(1985) method. Results: The results were divided into six categories as follows: 1) Inappropriate coping: unexpected event, overwork, lack of insight of preterm labor, 2) Burn out: multiple role, burden, role conflict. 3) Restrictions of lifestyle: uncomfortable hospital environment, wearisomeness, limitations of personal hygiene, 4) Physical discomfort: headache, flush, tremor, palpitations, 5) Psychological distress : concerns about fetus health status, fear of possible preterm delivery, lack of information, financial worries, 6) A transition to new lifestyle: share of household chores, communication with self-help group, careful lifestyle. Conclusion: The findings of this study will offer a better understanding of women's preterm labor experiences and suggest clues to nurses on how to improve the care they provide.

• Neonatal Medicine
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• 제28권1호
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• pp.1-6
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• 2021

Persistent pulmonary hypertension of the newborn (PPHN) is a consequence of the failure of a decrease in the elevated pulmonary vascular resistance after birth. Pulmonary vasodilators, including inhaled nitric oxide (iNO), have been the mainstream of targeted therapy for PPHN, but no drugs have been proven to be effective in preterm infants with PPHN. The fetus remains hemodynamically stable despite lower arterial oxygen tension and pulmonary blood flow as compared to full-term newborns. This adaptation is due to the lower oxygen requirement and high oxygen-carrying capacity of fetal circulation. The immature lungs of preterm infants are more vulnerable to reactive oxygen species, and the response of pulmonary vascular dilatation to blood oxygen tension is blunted in preterm infants. Recently, iNO has been reported to be effective in a selected group of preterm infants, such as those with prolonged preterm rupture of membrane-oligohydramnios-pulmonary hypoplasia sequence. PPHN in preterm infants, along with maximum supportive treatment based on fetal physiology and meticulous assessment of cardiovascular function, is in dire need of new treatment guidelines, including optimal dosing strategies for pulmonary vasodilators.

• Clinical and Experimental Pediatrics
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• 제62권7호
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• pp.245-251
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• 2019

Hemodynamically significant preterm patent ductus arteriosus (PDA) affects mortality; comorbidities such as necrotizing enterocolitis, intraventricular hemorrhage, and bronchopulmonary dysplasia; and adverse long-term neurodevelopmental outcomes in preterm infants, particularly in very low birth weight infants. However, recent studies have indicated that there is no consensus on the causal relationship between PDA and neonatal outcomes, the benefit of PDA treatment, the factors guiding the need for treatment, and optimal treatment strategies. Such uncertainty has resulted in wide variations in practice for treating preterm PDA between units, regions, and nations. Nowadays, there has been a paradigm shift to more conservative treatment for preterm PDA, and suggestions regarding selective management of preterm PDA considering risk factors and hemodynamic significance are increasing. Neonatologist-performed echocardiography and advances in modalities to assess hemodynamic significance such as biologic markers and near-infrared spectroscopy also help improve the efficacy of selective treatment of preterm PDA.

• 여성건강간호학회지
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• 제8권1호
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• pp.7-19
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• 2002

This study was to compare mother's postpartum physical health, mental health, and role performance between mothers with fullterm infants and preterm infants over 3 months postpartum period. The study used a correlational and longitudinal design and was secondary data analysis from a large study. A convenience sample of 132 mothers who had fullterm and preterm infants was followed up for 3 times (postpartum 1-2 days, 6 weeks, and 3 months) during the first 3 months postpartum period. Postpartum physical health was assessed by level of fatigue in the morning and in the afternoon, and number of physical symptoms. Postpartum mental health was assessed by positive affect, anxiety, and depression; and postpartum role performance was measured by role functional status. Mothers with preterm infants experienced higher levels of fatigue in the morning, lower positive affect, higher anxiety and higher depression over 3 data collection time points, compared to mothers with fullterm infants. Mothers with preterm infants also resumed lesser self-care activity and social and community activity than the counterparts. It implies that some aspects of preterm birth and caring for preterm infants continue to negatively affect the mother's health outcomes during the postpartum period.

• 여성건강간호학회지
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• 제16권4호
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• pp.336-347
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• 2010

Purpose: The purpose of this study was to identify the effect of relaxation therapy on state anxiety, preterm labor stress, blood pressure, skin temperature, pulse rate of pregnant women with preterm labor and heart rate of their babies. Methods: The participants were 55 pregnant women with preterm labor who hospitalized from May, 2009 to January, 2010. 29 participants were assigned to experimental group and the other 26 participants to control group. All of them were not have any other complications except preterm labor. The relaxation therapy was applied to the experimental group for 5 days. Data were analyzed by the SPSS/WIN 14.0 program. Results: The state anxiety score and the preterm labor stress score of experimental group were statistically significant lower than those of control group. In addition, the systolic and diastolic blood pressure, pulse rate of experimental group were statistically lower than those of control group. The skin temperature of experimental group was higher than that of control group. However, the fetal heart rate of experimental group was not statistically significant lower than fetal heart rate of control group. Conclusion: From these findings, it is concluded that relaxation therapy may be an effective nursing intervention for pregnant women with preterm labor.