• The Korean Journal of Physiology and Pharmacology
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• 제19권5호
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• pp.427-434
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• 2015

Significant evidence supports the role of the vestibular system in the regulation of blood pressure during postural movements. In the present study, the role of the vestibulo-spino-adrenal (VSA) axis in the modulation of blood pressure via the vestibulosympathetic reflex was clarified by immunohistochemical and enzyme immunoassay methods in conscious rats with sinoaortic denervation. Expression of c-Fos protein in the intermediolateral cell column of the middle thoracic spinal regions and blood epinephrine levels were investigated, following microinjection of glutamate receptor agonists or antagonists into the medial vestibular nucleus (MVN) and/or sodium nitroprusside (SNP)-induced hypotension. Both microinjection of glutamate receptor agonists (NMDA and AMPA) into the MVN or rostral ventrolateral medullary nucleus (RVLM) and SNP-induced hypotension led to increased number of c-Fos positive neurons in the intermediolateral cell column of the middle thoracic spinal regions and increased blood epinephrine levels. Pretreatment with microinjection of glutamate receptor antagonists (MK-801 and CNQX) into the MVN or RVLM prevented the increased number of c-Fos positive neurons resulting from SNP-induced hypotension, and reversed the increased blood epinephrine levels. These results indicate that the VSA axis may be a key component of the pathway used by the vestibulosympathetic reflex to maintain blood pressure during postural movements.

• Wind and Structures
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• 제14권4호
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• pp.301-319
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• 2011

The full-scale measurements are compared with the wind tunnel test results for the long-span roof latticed spatial structure of Shenzhen Citizen Center. A direct comparison of model testing results to full-scale measurements is always desirable, not only in validating the experimental data and methods but also in providing better understanding of the physics such as Reynolds numbers and scale effects. Since the quantity and location of full-scale measurements points are different from those of the wind tunnel tests taps, the weighted proper orthogonal decomposition technique is applied to the wind pressure data obtained from the wind tunnel tests to generate a time history of wind load vector, then loads acted on all the internal nodes are obtained by interpolation technique. The nodal mean wind pressure coefficients, root-mean-square of wind pressure coefficients and wind pressure power spectrum are also calculated. The time and frequency domain characteristics of full-scale measurements wind load are analyzed based on filtered data-acquisitions. In the analysis, special attention is paid to the distributions of the mean wind pressure coefficients of center part of Shenzhen Citizen Center long-span roof spatial latticed structure. Furthermore, a brief discussion about difference between the wind pressure power spectrum from the wind tunnel experiments and that from the full-scale in-site measurements is compared. The result is important fundament of wind-induced dynamic response of long-span spatial latticed structures.

• Structural Engineering and Mechanics
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• 제53권3호
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• pp.393-410
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• 2015

Two dimensional numerical models and physical models have been developed to study the highly nonlinear interactions between waves and breakwaters, but several of these models consider the effects of the structural dynamic responses and the shape of the breakwater axis on the wave pressures. In this study, a multi-material Arbitrary Lagrangian Eulerian (ALE) method is developed to simulate the nonlinear interactions between nonlinear waves and elastic seawalls on a coastal rubble mound breakwater, and is validated experimentally. In the experiment, a solitary wave is generated and used with a physical breakwater model. The wave impact is validated computationally using a breakwater - flume coupling model that replicates the physical model. The computational results, including those for the wave pressure and the water-on-deck, are in good agreement with the experimental results. A local breakwater model is used to discuss the effects of the structural dynamic response and different design parameters of the breakwater on wave loads, together with pressure distribution up the seawall. A large-scale breakwater model is used to numerically study the large-scale wave impact problem and the horizontal distribution of the wave pressures on the seawalls.

• Wind and Structures
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• 제21권2호
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• pp.119-158
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• 2015

The characteristics of the coherence functions of X axial, Y axial, and RZ axial (i.e., body axis) wind forces on the Shanghai World Trade Centre - a 492 m super-tall building with section varying along height are studied via a synchronous multi-pressure measurement of the rigid model in wind tunnel simulating of the turbulent, and the corresponding mathematical expressions are proposed there from. The investigations show that the mathematical expressions of coherence functions in across-wind and torsional-wind directions can be constructed by superimposition of a modified exponential decay function and a peak function caused by turbulent flow and vortex shedding respectively, while that in along-wind direction need only be constructed by the former, similar to that of wind speed. Moreover, an inductive analysis method is proposed to summarize the fitted parameters of the wind force coherence functions of every two measurement levels of altitudes. The comparisons of the first three order generalized force spectra show that the proposed mathematical expressions accord with the experimental results well. Later, the influences of coherence functions on wind-induced dynamic responses are analyzed in detail based on the proposed mathematical expressions and the frequency-domain method of random vibration theory.

• Nuclear Engineering and Technology
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• 제52권11호
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• pp.2638-2651
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• 2020

Nozzle corner cracks present at the intersection of reactor pressure vessels (RPVs) and inlet or outlet nozzles have been a persistent problem for a number of years. The fracture analysis of such nozzle corner cracks is very important and critical for the efficient design and assessment of the structural integrity of RPVs. This paper aims to perform an engineering critical assessment of RPVs with nozzle corner cracks subjected to several transients accompanied by pressurized thermal shocks. The critical crack size of the RPV model with nozzle corner cracks under transient loading is evaluated on failure assessment curve. In particular, the influence of cladding on the crack initiation of nozzle corner crack under thermal transients is studied. The influence of primary internal pressure and secondary thermal stress on the stress field at nozzle corner and SIF at crack front is analyzed. Finally, the influence of different crack size and crack shape on the final critical crack size is analyzed.

• Geomechanics and Engineering
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• 제30권5호
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• pp.471-478
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• 2022

Creep of soils has a significant impact on mechanical properties. The one-dimensional consolidation creep test, thermal analysis test, scanning electron microscope (SEM) test, and mercury compression test were performed on Guilin red clay to study the changes in bound water and microstructure during the creep process of Guilin red clay. According to the results of the tests, only free and weakly bound water is discharged during the creep of Guilin red clay. When the consolidation pressure p is in the 12.5-400.0 kPa range, it is primarily the discharge of free water; when the consolidation pressure p is in the 800.0-1600.0 kPa range, the weakly bound water is converted to free water and discharged. After consolidation creep, the microstructure of soil changes from granular overhead contact structure to flat sheet-like stacking structure, with a decrease in the number of large and medium pores, an increase in the number of small and micro pores, and a decrease in the fractal dimension of pores. The creep process of red clay is the discharge of weakly bound water as well as the compression of large pores into small pores and the transition of soil particles from loose to dense.

• Geomechanics and Engineering
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• 제32권4호
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• pp.411-426
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• 2023

Soft clay is widely distributed in the southeast coastal areas of China. Many large underground structures, such as subway stations and underground pipe corridors, are shallow buried in the soft clay foundation, so the dynamic characteristics of the soft clay must be considered to the seismic design of underground structures. In this paper, the dynamic characteristics of saturated soft clay in Shanghai under the bidirectional excitation for earthquake loading are studied by dynamic triaxial tests, comparing the backbone curve and hysteretic curve of the saturated soft clay under different confining pressures with those under different vibration frequencies. Considering the coupling effects of the confining pressure and the vibration frequency, a fitting model of the maximum dynamic shear modulus was proposed by the multiple linear regression method. The M-D model was used to fit the variations of the dynamic shear modulus ratio with the shear strain. Based on the Chen model and the Park model, the effects of the consolidation confining pressure and the vibration frequency on the damping ratio were studied. The results can provide a reference to the earthquake prevention and disaster reduction in soft clay area.

• Ocean Systems Engineering
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• 제6권2호
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• pp.129-141
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• 2016

Due to the structural complexity, the response of a flexible riser under axisymmetric loads is quite difficult to determine. Based on equilibrium conditions, geometrical relations and constitutive equations, an analytical model that can accurately predict the axisymmetric behavior of flexible risers is deduced in this paper. Since the mutual exclusion between the contact pressure and interlayer gap is considered in this model, the influence of the load direction on the structural behavior can be analyzed. Meanwhile, a detailed finite element analysis for unbonded flexible risers is conducted. Based on the analytical and numerical models, the structural response of a typical flexible riser under tension, torsion, internal and outer pressure has been studied in detail. The results are compared with experimental data obtained from the literature, and good agreement is found. Studies have shown that the proposed analytical and numerical models can provide an insightful reference for analysis and design of flexible risers.

• 한국연초학회지
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• 제17권2호
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• pp.170-176
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• 1995

Effect of circumference, net weight, and moisture content on the physicochemical propesties of cigarette were investigated. At the same net weight of cigarette, the pressure drop(E.P.D) of cigarette was increased as the circumference was decreased. Loseend and firmness were improved by reduction of circumference. In this condition, tar, nicotine, and carbon monoxide deliveries were decreased, and the puff count was significantly increased. When the moisture content of the cigarette were decreased, firmness and loseend were increased. Also in this condition nicotine and carbon monoxide tend to be increased. Key words : cigarette design, circumference, net weight.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part2
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• pp.788-789
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• 2006

Microstructure and soft magnetic properties of bulk amorphous and/or nanocrystalline $Fe_{73.5}Cu_1Nb_3Si_{13.5}B_9$ alloys prepared by consolidation at 5.5GPa were investigated. The relative density of the bulk sample 1 (from amorphous powders) was 98.5% and the grain sizes were about 10.6nm. While the relative density and grain sizes of bulk sample 2 (from nanocrystalline powders) are 98% and 20.1nm, respectively. Particularly, the bulk samples exhibited a good combined magnetic property: for Sample1, $M_s=125emu/g$ and $H_c=1.5Oe;$ for Sample2, $M_s=129emu/g$ and $H_c=3.3Oe$. The success of synthesizing the nanocrystalline Fe-based bulk alloys will be encouraging for the future development of bulk nanocrystalline soft magnetic alloys.