• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2003년도 제27회 추계학술대회
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• pp.78-78
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• 2003

Purpose: This event related fMRI study was to further our understanding about how different brain regions could contribute to effective access of specific information stored in long term memory. This experiment has allowed us to determine the brain regions involved in recognition of familiar faces among non familiar faces. Materials and Methods: Twelve right handed normal, healthy volunteer adults participated in face recognition experiment. The paradigm consists of two 40 familiar faces, 40 unfamiliar faces and control base with scrambled faces in a randomized order, with null events. Volunteers were instructed to press on one of two possible buttons of a response box to indicate whether a face was familiar or not. Incorrect answers were ignored. A 1.5T MRI system(GMENS) was employed to evaluate brain activity by using blood oxygen level dependent (BOLD) contrast. Gradient Echo EPI sequence with TR/TE= 2250/40 msec was used for 17 contiguous axial slices of 7mm thickness, covering the whole brain volume (240mm Field of view, 64 ${\times}$ 64 in plane resolution). The acquired data were applied to SPM99 for the processing such as realignment, normalization, smoothing, statistical ANOVA and statistical preference. Results/Disscusion: The comparison of familiar faces vs unfamiliar faces yielded significant activations in the medial temporal regions, the occipito temporal regions and in frontal regions. These results suggest that when volunteers are asked to recognize familiar faces among unfamiliar faces they tend to activate several regions frequently involved in face perception. The medial temporal regions are also activated for familiar and unfamiliar faces. This interesting result suggests a contribution of this structure in the attempt to match perceived faces with pre existing semantic representations stored in long term memory.

• 디자인학연구
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• 제13권4호
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• pp.233-242
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• 2000

1990년대는 유압굴삭기의 전통적 조형이 새롭게 모색 및 재해석되는 시기로 판단되었으며, 이는 2가지 방향으로 정리될 수 있다. 하나는 유압굴삭기의 전통적 이미지에 관한 부정적 해석에서 기인한 '탈(post-heavy equipment)중기적' 경향이며, 다른 하나는 고유성 유지와 개선이라는 긍정적 해석에서 기인한 '후기(late-)중기적' 경향이다. 이는 동일한 현상을 다양하게 바라볼 수 있는 패러다임과 관련하는 것으로 사료된다. 이 시기에 개발 및 시판된 8개 연구대상 모델 중 유압굴삭기의 조형 경향은, 일본 색채디자인연구소에서 개발한 이미지스케일 3상한에서 2상한으로 변화였으며, 예외적으로 코벨코는 1상한까지 이동하는 경향이 있었다. 이는 탈중기적 이미지를 디자인 전략으로 채택하고 있는 코벨코만의 경우였다. 아울러, 인적(入的)공간으로서의 캐빈의 변화는 장비 전체의 변화에서보다 좀더 1상한으로 이동하고 있는데, 이는 물적(物的)공간과 시각적 차별화를 위한 것으로 사료되었다.

• 한국토양비료학회지
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• 제45권1호
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• pp.93-97
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• 2012

This study was conducted to evaluate the efficiency of various inorganic and organic materials to improve physical properties of soil. Saline sodic soil (saturation percentage = 40.36%, $EC_e=5.15dS\;m^{-1}$, $pH_s=8.70$, $SAR=18.84(m\;mol\;L^{-1})^{1/2}$, bulk density =$1.49Mg\;m^{-3}$) was collected, brought to wire house and filled in pots after laboratory analysis for various parameters. Different sources of organic nutrients like farm manure (FM), press mud, compost, poultry manure and sesbania green manure were analyzed for their chemical composition. The experiment comprised of 12 treatments replicated thrice; $T_1$: control (recommended NPK), $T_2:{\frac{1}{2}}$ recommended NPK, $T_3$: FM at 1.5% by soil weight, $T_4$: pressmud at 1.5% by soil weight, $T_5$: compost at 1.5% by soil weight, $T_6$: poultry manure at 1.5% by soil weight, $T_7$: sesbania green manure at 1.5% by soil weight, $T_8:T_2$ + FM at 0.75% by soil weight, $T_9:T_2$ + pressmud at 0.75% by soil weight, $T_{10}:T_2$ + compost at 0.75% by soil weight, $T_{11}:T_2$ + poultry manure at 0.75% by soil weight, $T_{12}:T_2$ + sesbania green manure at 0.75% by soil weight. These treatments were applied using completely randomized (CR) design and appropriate time was given to decompose these organic nutritional sources. Seeds of wheat cultivar Sahar-2006 were sown. After harvesting the wheat, soil samples were collected from each pot and analyzed for various physical properties like bulk density, porosity and saturation percentage. An improvement in physical properties (bulk density, porosity and saturation percentage) of soil was noticed with the application of various organic nutritional sources but role of compost alone ($T_5$) remained prominent.

• 생명과학회지
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• 제17권9호통권89호
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• pp.1266-1271
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• 2007

본 연구의 대상은 40대 남성 중 흡연력이 10년 이상인 피험자 28명으로 횡경막호흡군, 마늘섭취군, 횡격막호흡+마늘섭취군, 대조군으로 나누었다. 횡격막 호흡 훈련은 4주간, 주 4회, 1회 20분 실시하였고, 운동강도는 호흡곤란척도의 2단계에서 5단계 사이로 설정하였다. 마늘 분말은 3 g씩, 아침, 저녁 식후, 하류 2회 섭취시킨 결과 다음과 같은 결론을 얻었다. 체지방률은 마늘섭취군만 실험 실시 후 감소하였고, 집단 간 비교에서 마늘섭취군이 대조군에 비해 낮은 것으로 나타났다. 심박수는 횡경막호흡군만 실험 실시 후 감소하였다. 수축기 혈압은 횡격막호흡+마늘섭취군만 실험 실시 후 감소하였다. IgG는 마늘섭취군과 횡격막호흡+마늘섭취군이 증가하였다. 이상의 결과를 통해 횡격막과 늑간의 효율적으로 사용하는 횡격막 호흡 훈련과 낮은 온도에서 가열하여 거부감을 줄인 마늘 분말 섭취는 흡연자의 신체조성, 심박수, 혈압 및 면역글로불린에 일부 긍정적인 효과가 나타나, 흡연자 뿐만 아니라 비흡연자들의 건강관리에도 적절한 중재 방법이 될 수 있을 것이다. 향후 흡연으로 인한 부작용의 예방과 개선을 위해 보다 종단적인 후속 연구가 요구되어진다.

• 한국가스학회지
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• 제11권1호
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• pp.23-28
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• 2007

본 본문에서는 LPG 용기용 가스밸브의 O-링과 밸브패킹의 밀봉결함과 크랙에 관련된 실험적 연구를 수행하고자 한다. LP 가스의 누출을 방지하기 위해 사용하는 O-링은 LPG 밸브의 밀봉 안전성을 확보하는 핵심부품으로 대단히 중요하다. 밸브패킹은 LPG 연료의 공급과 충전을 하는데, 가스 공급구를 열고 닫는 중요한 역할을 담당한다. 이들 두개의 밀봉부품에 대한 성능은 밸브의 누설 안전성과 장수명에 밀접한 관련이 있다. 연구결과에 의하면, O-링의 대부분은 파티션 부근의 결합불량과 과도한 압축률로 인해 원주방향으로 크랙이 발생하는 것으로 분석되었다. 그 이외의 결함으로 거론된 경우는 LP가스의 과도한 가스압력으로 인한 압출현상의 발생은 압출크랙을 일으키는 원인으로 작용하고 있다. 따라서 본 논문에서는 가스밸브의 누설 안전성을 확보하고 수명을 연장하기 위해 O-링과 밸브패킹에 대한 엄격한 품질관리와 인증제도의 도입을 권장하고자 한다. 결국에는 LPG용기용 밸브의 품질과 안전성 확보를 위해 밀봉장치에 대한 품질안전 보증제도를 도입해야 밸브를 오랫동안 사용할 수 있을 것이다.

• Geomechanics and Engineering
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• 제8권6호
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• pp.757-767
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• 2015

Rock mass is an important engineering material. In hydropower engineering, rock mass of bank slope controlled the stability of an arch dam. However, mechanical characteristics of the rock mass are not only affected by lithology, but also joints. On the basis of field geological survey, this paper built rock mass material containing parallel concentrated joints with different dip angle, different number under different stress conditions by PFC (Particle Flow Code) numerical simulation. Next, we analyzed mechanical property and fracture features of this rock mass. The following achievements have been obtained through this research. (1) When dip angle of joints is $15^{\circ}$ and $30^{\circ}$, with the increase of joints number, peak strength of rock mass has not changed much. But when dip angle increase to $45^{\circ}$, especially increase to $60^{\circ}$ and $75^{\circ}$, peak strength of rock mass decreased obviously with the increase of joints number. (2) With the increase of confining stress, peak strengths of all rock mass have different degree of improvement, especially the rock mass with dip angle of $75^{\circ}$. (3) Under the condition of no confining stress, dip angle of joints is low and joint number is small, existence of joints has little influence on fracture mode of rock mass, but when joints number increase to 5, tensile deformation firstly happened at joints zone and further resulted in tension fracture of the whole rock mass. When dip angle of joints increases to $45^{\circ}$, fracture presented as shear along joints, and with increase of joints number, strength of rock mass is weakened caused by shear-tension fracture zone along joints. When dip angle of joints increases to $60^{\circ}$ and $75^{\circ}$, deformation and fracture model presented as tension fracture zone along concentrated joints. (4) Influence of increase of confining stress on fracture modes is to weaken joints' control function and to reduce the width of fracture zone. Furthermore, increase of confining stress translated deformation mode from tension to shear.

• Advances in concrete construction
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• 제10권4호
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• pp.301-310
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• 2020

The following paper concentrates on the objective of studying the influences of extent of duration and temperature on the Pozzolanic properties as well as reactivity of locally existing natural clay of Nai Gaj, district Dadu, Sindh Pakistan. The activation of the clay only occurs through heating when temperature in a furnace chamber reaches 600, 700 and 800oC for 1, 2 and 3 hours and at 900 and 1000℃ for 1 and 2 hours. Furthermore, the strength activity index (SAI) of advanced pozzolanic material happens to be identified through 20% cement replacement for different samples of calcined clay as per ASTM C-618. The compressive strength test of samples had been operated for 7 and 28-days curing afterwards. The maximum compressive strength had been seen in mix E in which cement was replaced with clay calcined at 700℃ for 1 hour that is 27.05 MPa that is 24.31% more than that of control mix. The results gathered from the SAI verdicts the optimal activation temperature is 700℃ within a one-hour time period. The SAI at a temperature of 700℃ with a one-hour duration at 28 days is 124.31% which happens to satisfy the requirements of the new Pozzolanic material, in order to be applied in mortar/concrete (i.e., 75%). The Energy- dispersive spectrometry (EDS) along with the X-ray diffraction (XRD) have been carried out in means of verifying whether there is silica content or amorphous silica present in metakaolin that has been developed. The findings gathered from the SAI were validated, as the analysis of XRD verified that there is in fact Pozzolanic activity of developed metakaolin. Additionally, based on observation, the activated metakaolin holds a significant influence on the increase in mortar's compressive strength.

• Journal of Pharmaceutical Investigation
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• 제32권3호
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• pp.185-190
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• 2002

To improve the solubility of poorly water-soluble drug and to develop a sustained release tablets, the need for the technique, the formation of solid dispersion with polymeric materials that can potentially enhance the dissolution rate and extent of drug absorption was considered in this study. The 1:1, 1:4, and 1:5 solid dispersions were prepared by spray drying method using PVP K30, ethanol and methylene chloride. The dissolution test was carried out at in phosphate buffer solution at $37^{\circ}C$ in 100 rpm. Solid dispersed drugs were examined using differential scanning calorimetry and scanning electron microscopy, wherein it was found that felodipine is amorphous in the PVP K30 solid dispersion. Felodifine SR tablets were prepared by direct compressing the powder mixture composed of solid dispersed felodipine, lactose, Eudragit and magnesium stearate using a single punch press. In order to develop a sustained-release preparation containing solid dispersed felodipine, a comparative dissolution study was done using commercially existing product as control. The dissolution rate of intact felodipine, solid dispersed felodipine and its physical mixture, respectively, were compared by the dissolution rates for 30 minutes. The dissolution rates of felodipine for 30 minutes from 1:1, 1:4, 1:5 PVP K30 solid dispersion were 70%, 78% and 90%. However, dissolution rate offelodipine from the physical mixture was 5% of drug for 30 minutes. Our developed product Felodipine SR Tablet showed dissolution of 17%, 50% and 89% for 1, 4, and 7 hours. This designed oral delivery system is easy to manufacture, and drug releases behavior is highly reproducible and offers advantages over the existing commercial product. The dissolution rate of felodipine was significantly enhanced, following the formation of solid dispersion. The solid dispersion technique with water-soluble polymer could be used to develop a solid dispersed felodipine SR tablet.

• Ocean Systems Engineering
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• 제1권4호
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• pp.285-296
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• 2011

Spar platforms have several advantages for deploying wind turbines in offshore for depth beyond 120 m. The merit of spar platform is large range of topside payloads, favourable motions compared to other floating structures and minimum hull/deck interface. The main objective of this paper is to present the response analysis of the slack moored spar platform supporting 5MW wind turbine with bottom keel plates in regular and random waves, studied experimentally and numerically. A 1:100 scale model of the spar with sparD, sparCD and sparSD configuration was studied in the wave basin ($30{\times}30{\times}3m$) in Ocean engineering department in IIT Madras. In present study the effect of wind loading, blade dynamics and control, and tower elasticity are not considered. This paper presents the details of the studies carried out on a 16 m diameter and 100 m long spar buoy supporting a 90 m tall 5 MW wind turbine with 3600 kN weight of Nacelle and Rotor and 3500 kN weight of tower. The weight of the ballast and the draft of the spar are adjusted in such a way to keep the centre of gravity below the centre of buoyancy. The mooring lines are divided into four groups, each of which has four lines. The studies were carried out in regular and random waves. The operational significant wave height of 2.5 m and 10 s wave period and survival significant wave height of 6 m and 18 s wave period in 300 m water depth are considered. The wind speed corresponding to the operational wave height is about 22 knots and this wind speed is considered to be operating wind speed for turbines. The heave and surge accelerations at the top of spar platform were measured and are used for calculating the response. The geometric modeling of spar was carried out using Multisurf and this was directly exported to WAMIT for subsequent hydrodynamic and mooring system analysis. The numerical results were compared with experimental results and the comparison was found to be good. Parametric study was carried out to find out the effect of shape, size and spacing of keel plate and from the results obtained from present work ,it is recommended to use circular keel plate instead of square plate.

• Computers and Concrete
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• 제22권3호
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• pp.337-353
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• 2018

The present study focuses on examining the structural behaviour of steel-fibre-reinforced concrete (SFRC) beams under high rates of loading largely associated with impact problems. Fibres are added to the concrete mix to enhance ductility and energy absorption, which is important for impact-resistant design. A simple, yet practical non-linear finite-element analysis (NLFEA) model was used in the present study. Experimental static and impact tests were also carried out on beams spanning 1.3 meter with weights dropped from heights of 1.5 m and 2.5 m, respectively. The numerical model realistically describes the fully-brittle tensile behaviour of plain concrete as well as the contribution of steel fibres to the post-cracking response (the latter was allowed for by conveniently adjusting the constitutive relations for plain concrete, mainly in uniaxial tension). Suitable material relations (describing compression, tension and shear) were selected for SFRC and incorporated into ABAQUS software Brittle Cracking concrete model. A more complex model (i.e., the Damaged Plasticity concrete model in ABAQUS) was also considered and it was found that the seemingly simple (but fundamental) Brittle Cracking model yielded reliable results. Published data obtained from drop-weight experimental tests on RC and SFRC beams indicates that there is an increase in the maximum load recorded (compared to the corresponding static one) and a reduction in the portion of the beam span reacting to the impact load. However, there is considerable scatter and the specimens were often tested to complete destruction and thus yielding post-failure characteristics of little design value and making it difficult to pinpoint the actual load-carrying capacity and identify the associated true ultimate limit state (ULS). To address this, dynamic NLFEA was employed and the impact load applied was reduced gradually and applied in pulses to pinpoint the actual failure point. Different case studies were considered covering impact loading responses at both the material and structural levels as well as comparisons between RC and SFRC specimens. Steel fibres were found to increase the load-carrying capacity and deformability by offering better control over the cracking process concrete undergoes and allowing the impact energy to be absorbed more effectively compared to conventional RC members. This is useful for impact-resistant design of SFRC beams.