• Women's Health Nursing
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• v.13 no.3
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• pp.201-210
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• 2007

Purpose: The purposes of this study were to (a) explore the prevalence of sleep patterns of middle-aged women; (b) identify the relationship between subjective sleep quality and its related variables; and (c) predict the possible explanations of how the related factors affect subjective sleep quality of middle-aged women. Methods: A total of 256 women aged 40-60 years were purposely sampled and given self-administered questionnaires in a cross-sectional, correlation coefficient design. The data was analysed using t-test, one-way ANOVA, Pearson's correlation coefficients, and stepwise multiple regression. Results: The results were as follows; (a) a total of 40% of the women were poor sleepers as defined by a global PSQI score >5; (b) there were significant differences in quality of sleep related to type of family, number of present illnesses, and use of medication; (c) health promoting behaviors, family functioning, depression, and climacteric symptoms were significantly related to subjective sleep quality; and (d) 34% of variance in subjective sleep quality can be explained by climacteric symptoms, depression, type of family, and spouse. Conclusions: Our findings suggested a high proportion of poor sleeping in middle-aged women. Poor sleeping appeared to have poor health promoting behaviors, lower family functioning, worse depression, and higher climacteric symptoms. Climacteric symptoms, depression, type of family, and spouse were independent risk factors for poor sleeping. Nurse professionals should screen for sleep problems in middle-aged women with a biopsychosocial and behavioral aspect.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3091-3096
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• 2015

Worldwide, breast cancer is the most common malignant neoplasm and the second most common cause of cancer death in women. This malignancy is recognized to be estrogen-dependent and due to this feature, hormone replacement therapy is regarded as potentially dangerous in breast cancer survivors who seek relief of their menopausal symptoms. Whereas hot flashes are detected in nearly half of postmenopausal women with a relatively high frequency and severity, botanic sources of estrogens have been proposed as an alternative treatment. Nevertheless, estrogenic properties of these compounds suggest possibility of stimulating cancer recurrence or worsening prognosis in survivors. As well, effects in improving vasomotor climacteric changes is controversial. Many studies have considered the subject, some focusing on efficacy of phytoestrogens for control of menopausal symptoms, and others discussing effects of these compounds on breast cancer outcome in terms of survival or recurrence. The present article is a concise review of the effects of consumption of phytoestrogens on menopausal symptoms, namely hot flashes, and breast cancer recurrence and mortality in survivors of the disease. Overall, the major part of the current existing literature is in favor of positive effects of phytoestrogens on breast cancer prognosis, but the efficacy on menopausal symptoms is probably minimal at the best.

• Clinical and Experimental Pediatrics
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• v.54 no.1
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• pp.40-44
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• 2011

We present a case of tacrolimus-induced encephalopathy after successful kidney transplantation. An 11-year-old girl presented with sudden onset of neurologic symptoms, hypertension, and psychiatric symptoms, with normal kidney function, after kidney transplantation. The symptoms improved after cessation of tacrolimus. Magnetic resonance imaging (MRI) showed acute infarction of the middle cerebral artery (MCA) territory in the right frontal lobe. Three days later, she had normal mental function and maintained normal blood pressure with left hemiparesis. Follow-up MRI was performed on D19, showing new infarct lesions at both cerebral hemispheres. Ten days later, MRI showed further improvement, but brain single photon emission computed tomography (SPECT) showed mild reduction of uptake in both the anterior cingulate gyrus and the left thalamus. One month after onset of symptoms, angiography showed complete resolution of stenosis. However, presenting as a mild fine motor disability of both hands and mild dysarthria, what had been atrophy at both centrum semiovale at 4 months now showed progression to encephalomalacia. There are two points of interest in this case. First, encephalopathy occurred after administration of tacrolimus and improved after discontinuation of the drug. Second, the development of right-side hemiplegia could not be explained by conventional MRI; but through diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) of white matter tract, visualization was possible.

• Safety and Health at Work
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• v.9 no.2
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• pp.210-215
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• 2018

Background: The aims of this study were to determine the extent of workplace bullying perceptions among the employees of a Faculty of Medicine, evaluating the variables considered to be associated, and determining the effect of workplace bullying perceptions on their psychological symptoms evaluated by the Brief Symptom Inventory (BSI). Methods: This cross-sectional study was performed involving 355 (88.75%) employees. Results: Levels of perceived workplace bullying were found to increase with the increasing scores for BSI and BSI sub-dimensions of anxiety, depression, negative self, somatization, and hostility (all p < 0.001). One point increase in the workplace bullying perception score was associated with a 0.47 point increase in psychological symptoms evaluated by BSI. Moreover, the workplace bullying perception scores were most strongly affected by the scores of anxiety, negative self, depression, hostility, and somatization (all p < 0.05). Conclusion: The present results revealed that young individuals, divorced individuals, faculty members, and individuals with a chronic disease had the greatest workplace bullying perceptions with our study population. Additionally, the BSI, anxiety, depression, negative self, somatization, and hostility scores of the individuals with high levels of workplace bullying perceptions were also high.

• Journal of Oral Medicine and Pain
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• v.45 no.2
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• pp.34-38
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• 2020

Multiple myeloma is malignant neoplasm of plasma cells. Mandible lesions are rarely the first symptoms of multiple myeloma. While sensory dysfunction and pain are the main symptoms of traumatic trigeminal neuropathy, the same oral symptoms can appear in cases of multiple myeloma with developed mandible lesions. In addition, if the radiological osteoporosis or lytic lesion is seen in older patients, further examination is required to find the cause of the symptoms. In this paper, we present a case that was tentatively diagnosed as traumatic trigeminal neuropathy after left third molar extraction, but later confirmed as multiple myeloma.

• YAKHAK HOEJI
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• v.37 no.1
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• pp.84-88
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• 1993

Brovincamine is a selective cerebral vasodilator that was apparently produced via a slow calcium blockade. Brovincamine has been shown to increase ATP production and glucose and oxygen consumption in brain, improving energy metabolism. Also brovincamine inhibited platelet aggregation induced by ADP and collagen in vivo and in vitro via an increase of cAMP concentration, promoting therapeutic effects on cerebral circulatory disorders. So we investigated and represented the clinical effects and safety of brovincamine in patients with cerebral stroke. Thirty patients of cerebral stroke that was older than 2 months, who were 22 cases of cerebral infarction, 6 of cerebral embolism that originated from carebral infarction, 6 of cerebral embolism that originated from cardiac diseases, and 2 of cerebral embolism that originated from cardiac diseases, and 2 of cerebral hemorrhage, were administered of 20 mg of oral brovincamine three times daily for 8 weeks. Improvement rates of each symptom after 8 week administration were 30.8% for subjective symptoms, 76% for psychiatric symptoms and 65.6% for neurologic symptoms. In final global improvement rates, much improvement was 10%, improvement was 23.3% slight improvement is 36.7%, and no change was 30%. So global improvement rate including slight improvement was 70%. As for side effects, there were 3 cases of mild gastrointestinal symptoms, but there were no other subjective side effects and significant fluctuation in laboratory examination. Conclusively throughout the present study, brovincamine is judged to be well tolerated and effective in patients with cerebral stroke.

• Anxiety and mood
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• v.15 no.1
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• pp.29-34
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• 2019

Objective : To determine predictors of posttraumatic stress disorder (PTSD) symptoms in burn injured patients and evaluate factors for identifying high risk group of PTSD. Methods : This study examined sixty one patients aged in the range of 19-65 years with burn injuries. All subjects completed self-assessment inventories about PTSD (The PTSD Check List for DSM-5. PCL-5), depression (Patient Health Questionnaire-9, PHQ-9), embitterment (Posttraumatic embitterment disorder self-rating scale, PTED scale) and meaning of life (Meaning in Life Questionnaire, MLQ). Stepwise multiple regression and ROC curve analysis were the tools used for analysis. Results : The results revealed higher depression, embitterment and lower presence of meaning in life predicted severe PTSD symptoms. ROC analysis indicated PTED scale and PHQ-9 were useful for discriminating high risk group of PTSD. Conclusion : The present study established that the need to consider embitterment, depression and meaning of life for alleviation and prevention of PTSD symptoms in burn patients.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.34 no.1
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• pp.101-111
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• 2021

Objectives : Steroids are often administered to atopic patients as hormone preparations, often causing side effects. This study is intended to present the possibility of Korean medicine treatment for patients who have had side effects due to steroids in atopic dermatitis by relieving side effects and improving symptoms through Korean medicine such as Hwangryounhaedok-tang and Siryeong-tang. Methods : 2 patients who had atopic dermatitis and rebound phenomenon after steroids treatment were treated by herbal medicine, herbal acupuncture, acupuncture and external preparations. Photographs of the lesions, SCORAD(Scoring atopic dermatitis) index were used to evaluate the changes in symptoms. Results : The SCORAD index of the first patient improved from 55.6 to 24.3 in 4 months. The SCORAD index of the second patient improved from 44.7 to 21.3 in 3 months. Conclusions : In the situation where symptoms of atopic dermatitis patients due to steroid rebound phenomenon have worsened, Korean medicine treatments played a important role in alleviating symptoms and improving SCORAD index scores.

• Journal of information and communication convergence engineering
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• v.19 no.4
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• pp.234-240
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• 2021

As the number of pet dog-related businesses is rising rapidly, there is an increasing need for reliable pet dog health information systems for casual pet owners, especially those caring for older dogs. Our goal is to implement a mobile pre-diagnosis system that can provide a first-hand pre-diagnosis and an appropriate coping strategy when the pet owner observes abnormal symptoms. Our previous attempt, which is based on the fuzzy C-means family in inference, performs well when only relevant symptoms are provided for the query, but this assumption is not realistic. Thus, in this paper, we propose a hybrid inference structure that combines fuzzy association memory and a double-layered fuzzy C-means algorithm to infer the probable disease with robustness, even when noisy symptoms are present in the query provided by the user. In the experiment, it is verified that our proposed system is more robust when noisy (irrelevant) input symptoms are provided and the inferred results (probable diseases) are more cohesive than those generated by the single-phase fuzzy C-means inference engine.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.49 no.3
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• pp.157-162
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• 2023

Elongated styloid syndrome (ESS) can present with myriad symptoms that mimic common features of orofacial pain, such as temporomandibular joint disorders (TMJDs), often causing a challenge and delay in diagnosis. We report the case of a 52-year-old male with a three-year history of non-painful clicking during jaw movement initially diagnosed as TMJD-related internal derangement. The patient presented with a history of annoying jaw sounds for three years, described as a popping sound without bilateral clicking or crepitation. Tinnitus and progressive hearing loss were observed in the right ear, and a hearing aid was recommended by an otolaryngologist. The patient was initially diagnosed with TMJD and managed accordingly; nevertheless, his symptoms persisted. Imaging revealed prominent bilateral styloid process elongation that exceeded the recognized cut-off level of >30 mm for elongation. The patient was informed of his diagnosis and its treatment but opted only for further swallowing and auditory assessments of his ear and nose symptoms. Clinicians should consider including ESS as a differential diagnosis in patients presenting with non-specific chronic orofacial symptoms for timely diagnosis and favorable clinical outcomes.