• 대한정형외과 초음파학회지
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• 제5권2호
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• pp.75-80
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• 2012

목적: 체내 소형 이물질이 있는 것으로 의심되나 이학적 검사 및 단순 방사선 검사로 확인이 되지 않을 때, 이물질의 유무, 위치, 크기와 성상을 확인하고 제거하는데 있어 초음파 검사의 유용성을 알아보고자 하였다. 대상 및 방법: 2007년 3월부터 2012년 2월까지 수부 및 족부의 소형 이물질을 수술적으로 제거 받은 환자 중 수술 전 초음파 검사를 시행한 9명을 대상으로 하였다. 수상일로부터 수술일까지 이환 기간은 평균 32개월이었으며 부위는 수지 5예, 수장부 2예, 수배부 1예 및 족저부 1예였다. 2예에서 수술 전 단순 방사선 검사상 이물질을 확인할 수 있었으나 7예에서는 확인되지 않았으며 초음파 검사로 진단할 수 있었다. 고해상 선형 탐색자를 이용하여 초음파 검사를 시행하였으며 이물질의 유무, 위치 및 크기에 대해서 수술 소견과 비교하였다. 결과: 수술 전 초음파 검사에서 확인된 위치와 수술 소견이 잘 부합하였다. 이물질은 유리조각이 4예, 가시가 4예, 연필심이 1예였으며 평균 크기는 3.9 mm (2~7 mm) 였다. 결론: 체내에 소형 이물질이 잔류하는 것으로 의심되는 환자에서 초음파 검사는 진단 및 치료에 있어 유용한 검사로 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7793-7797
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• 2014

Objective: The aim of this study was to evaluate predictive role of risk of malignancy index in discriminating between benign and malignant adnexal masses preoperatively. Methods: This retrospective study was conducted with a total of 569 patients with adnexal masses/ovarian cysts managed surgically at our clinic between January 2006 and January 2012. Obtained data from patient files were age, gravidity, parity, menopause status, ultrasound findings and CA125 levels. For all patients ultrasound scans were performed. For the assessment of risk of malignancy index (RMI) Jacobs' model was used. Histopathologic results of all patients were recorded postoperatively. Malignancy status of the surgically removed adnexal mass was the gold standard. Results: Of the total masses, 245 (43.1%) were malignant, 316 (55.5%) were benign and 8 (1.4%) were borderline. The mean age of benign cases was lower than malign cases ($35.2{\pm}10.9$ versus $50.8{\pm}13.4$, p<0.001). Four hundred and five of them (71.2%) were in premenopausal period. Malignant tumors were more frequent in postmenopausal women (81% versus 29%, p<0.001). All ultrasound parameters of RMI were statistically significantly favorable for malignant masses. In our study ROC curve analysis for RMI provided maximum Youden index at level of 163.85. When we based on cutoff level for RMI as 163.85 sensitivity, specificity, PPV, NPV was calculated 74.7%, 96.2%, 94% and 82.6%, respectively. Conclusions: RMI was found to be a significant marker in preoperative evaluation and management of patients with an adnexal mass, and was useful for referring patients to tertiary care centers. Although utilization of RMI provides increased diagnostic accuracy in preoperative evaluation of patient with an adnexal mass, new diagnostic tools with higher sensitivity and specificity are needed to discriminate ovarian cancer from benign masses.

• 대한후두음성언어의학회지
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• 제15권1호
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• pp.16-20
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• 2004

Purpose : To assess perceptual, acoustic and aerodynamic measure of voice quality in patients with unilateral vocal cord paralysis before and after type I thyroplasty. Methods : The clinical records of patients operated type I thyroplasty in the Departement of otorhinoalryngolgy, Yongdong Severance hospital from November 2001 to November 2003 were reviewed. All patients uderwent a vocal function evaluation including perceptual, acoustic and aerodynamic measures of voice preoperative and on $60^{th}$ postoperative day. The perceptual and acoustic measures were obtained from recording of patients' reading a 'Sanchak' passage. The perceptual evaluation was performed by 2 speech pathologist using a 4-point rating scale. Acoustic parameters(voice range profile low(RAL), voice range profile high(RAH), average fundamental frequency(AFX), closed quotient, harmonic to noise ratio, jitter and shimmer) were investigated by Lx speech studio. Mean flow rate(MFR), subglottic pressure(Psub) and intensity were measured using the Phonatory function analyzer. The maximum phonation time was also measured. The data were statistically analyzed. A paired t-test (p<0.1) was used to compare preoperative and postoperative results. And multiple regression test was used to find which parameter was most correlated to improvement of postoperative voice quality. Results : Among aerodynamic parameters, Psub $(88.11mmH_2O{\rightarrow}58.7mmH_2O)$, MPT(7.87sec${\rightarrow}$12.53sec), MFR (359.8ml/sec${\rightarrow}$161.06ml/sec) were statistically improved. AFx(205.5Hz${\rightarrow}$163.27Hz), AQx(23.9%${\rightarrow}$48.3%), RAL, RAH. Jotter and shimmer were improved. In multiple regression test, AFx and AQx was noted as the two meost correlated parameters to improvement of postoperative breathiness. But general grade of voice quality was more correlated to Psub and shimmer. Conclusion : Vocal fold medialization procedures effectively reduce glottic gap. Increasing of contact area of both vocal folds induced improvement in aerodynamic parameters and leaded stabilizing of vocal fold vibration. That effect results in improvement in acoustic parameters (shimmer, jitter, signal-to-noise ratio, voice range profile) and voice quality.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5455-5459
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• 2013

Background: The risk of malignancy index (RMI) for the evaluation of adnexal masses is a sensitive tool in certain populations. The best cut off value for RMI 1, 2 and 3 is 200. The cut off value of RMI-4 to differentiate benign from malignant lesions is 450. Our aim was to evaluate the efficiency of four different malignancy indexes (RMI1-4) in a homogeneous population. Materials and Methods: We evaluated a total of 153 non-pregnant women with adnexal masses who did not have a history of malignancy and who were above 18 years of age. Results: A cut-off value of 250 for RMI-1 provided 95.9% inter-observer agreement, yielding 95.9% specificity, 93.5% negative predictive value, 75.0% sensitivity and 82.8% positive predictive value. A cut-off value of 250 for RMI-1 showed high performance in preoperative diagnosis of invasive malignant lesions than cut-off value of 200 in our population. A cut-off value of 350 for RMI-2 provided 94.5% inter-observed agreement, yielding 94.2% specificity, 93.4% negative predictive value, 75.0% sensitivity and 77.4% positive predictive value. RMI-2 showed the higher performance when the cut-off value was set at 350 in our population. A cut-off value of 250 provided 95.2% inter-observer agreement, yielding 95.0% specificity, 93.2% negative predictive value, 75.0% sensitivity, and 88.0% positive predictive value. RMI-3 showed the highest performance to diagnose malignant adnexal masses when the cut-off value was set at 250. In our study, RMI-4 showed similar statistical performance when the cut-off value was set at 400 [(Kappa: 0.684/p=0.000), yielding 93.8% inter-observer agreement, 93.4% specificity, 93.4% negative predictive value, 75.0% sensitivity, and 75.0% negative predictive value]. Conclusions: We showed successful utilization of RMIs in preoperative differentiation of benign from malignant masses. Many studies conducted in Asian and Pacific countries have reported different cut-off values as was the case in our study. We think that it is difficult to determine universally accepted cut-off values for RMIs for common use around the globe.

• 대한두경부종양학회지
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• 제35권2호
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• pp.11-17
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• 2019

Background/Objectives: Papillary thyroid carcinoma (PTC) has generally an indolent character with a good prognosis. However, recurrence remains a major concern for the patients during their lifetime. Despite the slowly progressing character of PTC, recurrence can occur within a short period after initial surgery. This study aimed to determine the clinical findings and cause of recurrence in patients who underwent re-operative surgery due to neck node recurrence by reviewing the CT (computed tomographic) scan imaging of the recurrence of PTC retrospectively. Materials & Methods: We reviewed the medical records of patients referred to Ajou University Hospital from January 2002 to January 2018. All patients had re-operative surgery due to neck node recurrence and CT scan results of preoperative evaluation and postoperative follow up. Over this period, 110 patients who underwent re-operation due to neck node recurrence with a CT scan were included in our cohort, resulting in a total of 220 re-operations. Results: The time from initial operation to first re-operation was examined in 110 patients. The median time to re-operation was 28 months, with a range of 4 months to 186 months. Most re-operations (82.7%) occurred within the first five years, 43.6% were in the first two years from the initial surgery. The result of the retrospective CT review showed newly developed cases (21,19.1%), missed diagnosis cases (42,38.2%), real recur cases after surgery (33,30.0%), and remnant lymph nodes (LNs) cases (14,12.7%). We further sub-analyzed 14 cases with remnant LNs. Reasons for remnant LNs included insufficient operation (N=5) and beyond general surgical extent. (N=9). Conclusion: Re-operation due to cervical lymph node recurrence is mostly a persistent disease. They included a missed diagnosis and incomplete operation. These finding may reduce the reoperation of cervical lymph node recurrence by accurate preoperative evaluation and complete surgical resection at the initial surgery.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제12권2호
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• pp.9-20
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• 1990

A series of 19 cases with maxillary hyperplasia and mandibular retrognathia were operated on by simultaneous superior repositioning of the maxilla after Le Fort I osteotomy and anterior repositioning of the mandible after bilateral sagittal split ramus osteotomies with or without osteotomy of the inferior border of the mandible. These were evaluated by retrospective cephalometric and computer analysis for the longitudinal skeletal and dental changes for an average of 17.1 months after surgery. For stabilization of the osteotomized segments, the authors used wire osteosynthesis by means of bilateral infraorbital and zygomatic buttress suspension wire at the maxilla, and direct interosseous wire at the split segments of the mandibular rami. Results show generally good stability after simultaneous maxillary and mandibular surgery with wire osteosynthesis, and a minimal to moderate tendency toward skeletal and dental relapse. This article is a preliminary study to defy the efficiency of the wire osteosynthesis (wo)compared with rigid internal fixation (RIF) for simultaneous maxillary and mandibular surgery. 1. The vertical relapse rate of the A point after superior repositioning of the maxilla is 2.2%. 2. The horizontal relapse rate of the B point after advancement of the mandible is 18.3%. 3. The condyle is distracted inferiorly and slightly posteriorly at the immediate postoperative period. 4. At the long term follow up examination, the condyle presents tendency of return to the preoperative position. 5. Condylar segment angle is decreased at the immediate postoperative period, and at the long term follow up evaluation, the angle is increased. 6. Gonial angle is increased at the immediate postoperative period, and then is decreased at the long term follow up evaluation. 7. The dentition is satisfactory with acceptable movement at the long term follow up evaluation. 8. At the mandibular free body analysis, genioplasty shows good stability. 9. Wire osteosynthesis provides excellent stabilization for the simultaneous maxillary and mandibular surgery.

• Archives of Plastic Surgery
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• 제39권6호
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• pp.631-635
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• 2012

Background The evaluation of a breast after breast reconstruction depends on a surgeon's subjective criteria. We used computed tomography (CT) scans to obtain an objective evaluation of the postoperative results by measuring the breast volume of patients who had undergone breast reconstruction using pedicled transverse rectus abdominis myocutaneous (TRAM) flaps. This research will help in the objective postoperative evaluation of reconstructed breasts, and also in the preoperative flap size designs. Methods A total of 27 patients underwent breast reconstruction using pedicled TRAM flaps after mastectomy from September 2007 to July 2010. Of these, 10 patients who were followed up and underwent CT scans 2 or more times during the follow-up period were included in this study. We evaluated the change in breast volume over time using CT scans, and the interval breast volume change between CT scans. Results All of the 10 patients' reconstructed breasts showed a volume decrease over time. The breast volume changes in the intervals between CT scans were as follows: 5.65% decrease between the first CT and second CT scan, 2.3% decrease between the second CT and third CT scan, (statistically significant) and 1.89% decrease between the third CT and forth CT scan. (not statistically significant). Conclusions This research shows the possibility of objectively evaluating the postoperative breast volume changes. The findings will be helpful in designing the size of TRAM flaps to use on defects after mastectomy. Based on these results, we should also closely observe the reconstructed breast volume for at least 2 years.

• 방사선산업학회지
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• 제17권4호
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• pp.391-396
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• 2023

Currently, state-of-the-art devices such as SPECT, PET/CT, and PET/MRI are rapidly spreading nationwide, and the penetration rate of nuclear medical devices is also ranked fifth in the world. However, PET/MRI's system is slower and less common because it is more complex than PET/CT. The purpose of this study is to provide optimal information on PET/MRI according to the patient's disease. The subjects obtained information on head and neck cancer, pediatric patients, breast cancer patients, heart disease patients, lung cancer patients, and rectal cancer patients. We tried to accumulate protocols by obtaining a lot of information about each disease. In diagnosing head and neck cancer, it is believed that it is highly likely to be used in evaluating preoperative stage determination, recurrence and remote metastasis after treatment, and unclear primary cervical lymph node metastasis. Diagnosis and continuous follow-up of pediatric patients can increase patient benefits by minimizing radiation exposure. Breast cancer provides a comprehensive evaluation of the clinical need to determine the extent of disease in breast and local lymph nodes and the systematic stages of early diagnosis or recurrence. In diagnosing heart disease patients, MR-based PET motion correction helps to realize the full potential of PET images. For lung cancer patients, the clinical value and usefulness of the resolution and detection ability of integrated PET/MRI for soft tissues such as lung cancer will be sufficient. In diagnosing rectal cancer patients, the detection of missing residual diseases can change the clinical response evaluation for rectal cancer patients treated with TNT, and both the initial stage and treatment response evaluation are possible. Therefore, this literature study provided basic clinical data for PET/MRI tests.

• 대한관절경학회지
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• 제6권2호
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• pp.115-120
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• 2002

목적 : 후방십자인대의 단독 손상군과 동반 손상군에서 재건술 시행 후 발생되는 후방 전위의 정도를 분석하고 슬관절의 기능적 평가와 비교하고자 하였다. 대상 및 방법 : 1994년 6월부터 2000년 6월까지 동종 아킬레스건을 이용한 관절경적 후방십자인대 재건술을 시행받은 45명을 대상으로 하였으며 평균 추시 기간은 49개월이었다. 후방 전위 정도는 후방 부하 방사선 사진과 KT-2000 슬관절계를 이용하였고 슬관절 기능 평가는 Lysholm score와 IKDC evaluation form을 이용하였다. 결과 : 건측과 비교한 방사선학적 후방 전위의 차이는 단독 손상군에서 술 전 평균 11.83 mm, 최종 추시 6.38 mm였고, 동반 손상군에서 술 전 12.7 mm, 최종 추시 6.7 mm이었다. 최종 추시에서 단독 손상군과 동반 손상군의 KT-2000슬관절계를 이용한 후방 전위는 각각 평균 3.5 mm, 4.1 mm, Lysholm score는 평균 87.4점, 81.2점, IKDC 평가표상 grade B 이상은 16례$(88.9\%)$, 23례$(85.2\%)$ 조사되었다. 결론 : 후방십자인대 재건술 후 동반 손상군이 단독 손상군에 비해 후방 전위가 좀더 잔존하는 경향을 보였으나 통계학적인 의미는 없었고 두 군에서 후방 전위의 정도와 슬관절의 기능적 평가와는 상관관계가 없었다.

• Radiation Oncology Journal
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• 제16권3호
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• pp.259-264
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• 1998

목적 :상악동암에서 수술 전 방사선 치료를 시행함으로써 안면 보존의 가능성이 어느 정도 되는지를 알아보고자 하였다. 대상 및 방법 : 1986년 6월부터 1990년 9월까지 상악동암으로 방사선치료를 받은 42례의 환자를 대상으로 후향적 분석을 시행하였다. 환자의 연령은 24세에서 75세로 중간값은 56세였으며, 남자 27예, 여자 15예였다. 병기별 분포는 T2 2예, T3 19예, T4 21예로 진단 당시 대부분 진행된 상태였다. 조직학적으로는 편평 상피암 38예, 미분화 세포암 1예, 이행 상피암 1예, 선양 낭종암 2예였다. 모든 환자에 대해 동측 부비동을 포함하는 쌍쐐기빔 방법의 방사선치료를 시행하였다. 방사선 치료선량은 50.4-70.2 Gy로 중간값은 70.2 Gy였다. 11례의 환자에 대해 방사선치료와 유도 화학요법을 병행하였다. 화학요법은 5-fluorouracil과 cisplatin으로 2회 시행하였다. 대상 환자의 추적기간은 3개월에서 92개월로 중간값은 16개월이었다. 방사선치료 후 6 내지 8개월 경과 후 전산화단층촬영을 실시하여 병소의 반응을 평가하였다. 완전관해가 된 경우는 계속 추적검진만 하였으며 병변이 의심되는 경우는 콜드웰-뤼크 수술을 시행하여 확인하였다. 병변이 확인된 경우는 상악동전절제술을 시행하였다. 결과 : 방사선 및 화학요법 시행 후 9예 (21.4$\%$)에서 완전관해를 보였고 33예 (88.6$\%$)에서 잔여병변이 확인되었다. 완전관해를 보인 9예의 환자 중 7예가 국소제어되었으며 2예에서 국소재발하였다. 잔여병변이 있는 33예의 환자 중 10예에서 근치적 수술이 가능하였고 그 중 2예에서 국소제어가 되었다. 전체 환자의 5년 생존율은 23.1$\%$였고 5년 무병생존율은 16.7$\%$였다. 방사선치료에 대한 반응 (P<0.05) 만이 생존율에 영향을 미치는 유의한 인자였다. 결론 : 방사선치료에 대한 반응만이 생존율에 영향을 미치는 유의한 인자였다. 전체적으로 7예(16.7$\%$) 에서 수술 전 방사선치료로 안면보존이 가능하였다.