• 여성건강간호학회지
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• 제28권1호
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• pp.38-45
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• 2022

Purpose: Various individual and social factors influence depression in pregnant women. The purpose of this study was to identify the influence of socioeconomic status, health behaviors, and health status on depression of pregnant women in Korea. Methods: This study analyzed data from the 2019 Korean Community Health Survey conducted from August to October 2019. A structural questionnaire with Patient Health Quetsionnaire-9 (PHQ-9), health behavior, health status, and psychological characteristics was used. The data of 1,096 pregnant women between the ages of 19 and 55 years were analyzed using descriptive statistics, independent-test and chi-square tests, and multiple regression. Results: The mean score of prenatal depression as measured by the PHQ-9 during pregnancy was 2.35 points out of 0 to 27 points. Low income (B=0.69, p<.001), low-education level (B=0.70, p<.001), skipping breakfast (B=0.34, p=.001), less than 8 hours of sleeping (B=0.26, p=.009), binge drinking during pregnancy (B=0.46, p=.001), and stress (B=1.89, p<.001) were significantly associated with increased depression scores. In contrast, depression scores significantly decreased as subjective health status (B=-0.59, p<.001) and subjective oral health status (B=-.17, p=.003) increased. Conclusion: Findings support the need for healthcare policies and clinical screening to alleviate prenatal depression, especially for pregnant women with low socioeconomic status, poor health behavior, poor health status, and high stress.

• 여성건강간호학회지
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• 제19권1호
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• pp.48-56
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• 2013

Purpose: The purpose of this study was to identify the influencing factors of mothers' confidence in their maternal role during the early postpartum period. Methods: Participants were 178 postpartum women who delivered at three specialized obstetrics and gynecology facilities and used the postpartum care facility in city B. Data were collected from February to April, 2012 using the scales of measurements of self-confidence in maternal role performance, maternal self-esteem, mother-to-infant attachment, social support, and childcare stress. Descriptive statistics, Pearson correlation coefficients, and stepwise multiple regression were used with the SPSS/WIN 18.0 program to analyze the data. Results: The scores for self-confidence in the maternal role showed significant negative correlations with the scores of childcare stress (r=-.40, p<.001). Parity and maternal attachment were significant predictors and accounted for 97.4% of the variance in self-confidence in the maternal role. Conclusion: To strengthen self-confidence in the maternal role of early postpartum mothers, prenatal class programs need to be complemented in order to reduce childcare stress and promote mother-to-infant attachment.

• 한국지역사회생활과학회지
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• 제17권3호
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• pp.109-121
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• 2006

This study examines the relationship between mother's stress and cortisol level during late pregnancy and how it changes into postpartum periods. Thirty one families were recruited from Daejeon and Incheon in South Korea. The major findings were as follows: (1) The level of mothers' cortisol followed the typical diurnal pattern of decline throughout the day. Further longitudinal analysis revealed that the level of Korean mothers' cortisol steadily lowered from the 8th prenatal month to the 6th postnatal month. (2) During pregnancy, mothers reported to experience changes in physical activities, daily routines, eating habits, types or amount of social activities and sleeping habits. Among these they were stressed the most by changes in physical activities and social activities. (3) The results of postpartum depression tests conducted at two months after giving birth showed mothers at this time were mostly stressed from difficulty sleeping and unnecessary self criticism. (4) The level of psycho social stress in mothers at six months after giving birth was mainly on social roles and the questions about self reliance marked the highest points. (5) Overall, there was a tendency for the level of maternal stress to decrease definitely from before and after the delivery and even though the level of stress was steadily decreasing up to 6th postpartum month it was not as sharp as those of before and after the birth of the babies. The level of cortisol analysis also showed the same obvious tendency.

• 대한의생명과학회지
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• 제15권3호
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• pp.249-255
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• 2009

All living things have been developed efficient strategies to cope with external and internal environmental changes via a process termed 'homeostasis'. However, chronic prenatal maternal stress may significantly contributes to pregnancy complications by disturbing hypothalamic-pituitary-adrenal (HPA) axis and the automatic nervous system (ANS), and results in unfavorable development of the fetus. Dysregulation of these two major stress response systems lead to the increased secretion of the glucocorticoids (GCs) which are known to be essential for normal development and the maturation of the central nervous system. As Hox genes are master key regulators of the embryonic morphogenesis and cell differentiation, we aimed to determine the effects of dexamethasone, a potent synthetic glucocorticoid, on gene expression in mesenchymal stem cell C3H10T1/2. Analysis of 39 Hox genes based on reverse transcription PCR (RT-PCR) method revealed that the expression patterns of Hox genes were overall upregulated by long dexametasone treatment. These results indicate that maternal stress may have a deleterious effect on early developing embryo through the stress hormone, glucocorticoid.

• 한국산학기술학회논문지
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• 제11권3호
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• pp.1153-1162
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• 2010

본 연구의 목적은 임산부의 임산부 체조 참여에 따른 신체평가 및 임신 스트레스에 미치는 영향을 규명하는데 있으며 연구대상은 2009년 현재 서울 강북지역에 거주하면서 임신을 한 20세에서 39세 사이의 성인여성을 대상으로 임산부 체조 참여자 49명, 비참여자 51명 총 100명을 대상으로 하였으며 SPSS Windows 15.0 Version을 이용하여 분석 목적에 따라 전산처리 하였으며 자료분석을 위하여 본 연구에서 사용할 분석기법은 빈도분석(Frequency), 요인분석(factor analysis), 신뢰도분석(reliability analysis), t-test, 일원변량분석(one-way ANOVA) 및 사후분석(Scheffe), 중다회귀분석(multiple regression analysis)을 실시하였다. 이러한 과정을 통한 구체적인 통계분석 결과는 다음과 같다. 첫째, 임산부들의 인구통계학적 특성에 따른 신체평가 및 임신스트레스의 차이는 부분적으로 나타났다. 둘째, 임산부들의 임산부 체조 참여유무에 따른 신체평가 및 임신스트레스의 차이는 부분적으로 나타났다. 셋째, 임산부들의 신체평가가 임신 스트레스에 부분적으로 영향을 미치는 것으로 나타났다.

• 한국산학기술학회논문지
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• 제16권3호
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• pp.2020-2028
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• 2015

본 연구는 Mercer의 어머니되기 이론적 모델에서 제시한 태아애착행위의 영향 변수(임신스트레스, 자존감, 결혼적응도, 자아통제감, 산전우울)를 고려하여 임부의 태아애착행위에 영향을 미치는 요인을 파악하기 위해 수행되었다. 산전검사를 위해 산부인과와 보건소에 방문한 임부 140명을 대상으로 2014년 8월 23일에서 11월 25일에 걸쳐 자가보고식 형태의 설문조사를 하였다. 자료는 SPSS 20을 이용하여 평균과 표준편차, t-test, ANOVA, Pearson의 상관관계, 단계적 회귀분석을 통해 분석되었다. 연구결과는 다음과 같다. 태아애착행위는 30세 이하 임부에서 31세 이상 임부보다 유의하게 높았고(t=2.79, p=.004), 초임부에서 경임부보다 유의하게 높은 것으로 나타났다(F=3.27, p=.041). 태아애착행위는 임신스트레스(r=-0.22, p=.009)와 역상관관계를 보였고, 자존감(r=0.45, p<.001), 결혼적응도(r=0.42, p<.001), 자아통제감(r=0.24, p=.005)과는 정상관관계를 나타냈다. 임부의 태아애착행위에 영향을 미치는 요인은 자존감, 결혼적응도, 나이로 밝혀졌으며, 전체 모형의 26.1%를 설명하였다. 본 연구결과는 산전관리를 통해 임부의 자존감과 결혼적응도에 대한 이해 및 사정이 필요하고, 고령 임부의 태아애착행위 증진 중재의 개발 및 적용이 필요함을 시사한다.

• 대한간호학회지
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• 제43권2호
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• pp.225-235
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• 2013

Purpose: This prospective cohort study was done to investigate recall bias to antepartum variables measured at postpartum periods and predictors of postpartum depression. Methods: Participants were 215 women who answered a self-administered questionnaire which included demographics, Postpartum Depression Predictors Inventory-Revised and Korean version of Edinburgh Postpartum Depression Scale at antepartum 36-40 weeks and postpartum 2 weeks and 6 weeks. Data were analyzed using kappa, and hierarchical multiple logistic regression. Results: Agreement between antepartum variables at both antepartum and two postpartum periods was relatively high (${\kappa}$=.55- .95). Postpartum depression rates were 36.3% and 36.7% at two follow-up points. In hierarchical multiple logistic regression analysis, prenatal depression (OR=4.32, 95% CI: 1.41-13.19; OR=5.19, 95% CI: 1.41-19.08), social support (OR=1.40, 95% CI: 1.18-1.66; OR=1.27, 95% CI: 1.06-1.53) and maternity blues (OR=4.75, 95% CI: 1.89-11.98; OR=4.22, 95% CI: 1.60-11.12) were commonly associated with postpartum depression at two follow-up points. Child care stress (OR=1.85, 95% CI: 1.01-3.37) was only associated with postpartum depression at 2 weeks postpartum and pregnancy intendedness (OR=1.57, 95% CI: 1.09-2.27) was only associated with postpartum depression at 6 weeks postpartum. Conclusions: The results indicate a need to apply nursing interventions such as prenatal education and counseling with families from antenatal period.

• Korean Journal of Acupuncture
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• 제23권4호
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• pp.157-167
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• 2006

목적 : 인삼은 전통적으로 학습과 기억능력 증진 및 각종 질병치료에 우수한 효과가 있는 것으로 알려져 있다. 본 연구에서는 이러한 인삼약침이 소음스트레스가 유발된 태아쥐의 해마 및 시상하부에서 nitric oxide synthase에 미치는 영향을 관찰하였다. 방법 : 인삼약침이 소음스트레스에 미치는 영향을 연구하기 위하여 태아기에 소음스트레스를 유발하고 생후 4주 후 7일간 인삼약침을 투여한 후 NADPH-d 조직화학법을 시행하였다. 결과 : 소음스트레스는 태아쥐의 해마 및 시상하부에서 NOS 발현이 유의하게 증가하였다. 2. 인삼약침은 해마 CA1에서만 소음스트레스에 의해서 증가된 NOS 발현을 유의하게 억제하였다 3. 인삼약침은 시상 하부 PVN, DMH 및 LHA에서 소음스트레스에 의해서 증가된 NOS 발현을 유의하게 억제하였다. 결론 : 본 연구를 통하여 인삼약침이 소음스트레스가 유발된 태아쥐의 해마 및 시상하부에서 증가된 NOS 발현을 유의하게 억제시켜 태아의 스트레스 자극에 인삼약침치료가 유의한 효과가 있음을 확인하였다.

• Journal of Genetic Medicine
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• 제11권2호
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• pp.56-62
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• 2014

Purpose: To assess the outcomes of increased fetal nuchal translucency (NT), to aid in prenatal counseling and management in our practice. Materials and Methods: We retrospectively reviewed the medical records of patients who underwent first trimester fetal karyotyping using chorionic villi sampling (CVS) and second trimester level II sonography for a fetal NT thickness ${\geq}3.0mm$ between 11 weeks and 13 weeks 6 days' gestation, at Gyeongsang National University Hospital. Pediatric medical records and a telephone interview were used to follow-up live-born children. Exclusion criteria included incomplete data and CVS for other indications. Results: Seventy cases met the inclusion criteria (median NT thickness, 4.7 mm; range, 3.0-16.1 mm). Twenty-nine cases (41.4%) were aneuploid. The prevalence of chromosomal defects increased with NT thickness: NT 3.0-3.4 mm, 16.7%; NT 3.5-4.4 mm, 27.3%; NT 4.5-5.4 mm, 66.7%; NT 5.5-6.4 mm, 37.5%; NT ${\geq}6.5mm$, 62.5%. The most common karyotype abnormality was trisomy 18 (n=12), followed by trisomy 21 (n=9). In chromosomally normal fetuses (n=41), fetal death occurred in 2 cases (4.9%), and structural malformations were found in 11 cases (26.8%). In chromosomally and anatomically normal fetuses (n=28), one child had neurodevelopmental delay (3.6%). Twenty-eight infants who had a prenatal increased NT were alive and well at follow-up (40%). Conclusion: Outcomes of increased fetal NT might help inform prenatal counseling and management. The high prevalence of chromosomal defects associated with increased fetal NT implies that CVS should be performed in the first trimester, particularly considering the stress associated with an uncertain diagnosis.

• 아동학회지
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• 제36권3호
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• pp.77-92
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• 2015

The purpose of this study was to employ the Latent Growth Curve Model to investigate the developmental trajectories of maternal depressive symptoms and to identify predictors that might have an effect on change and the level of developmental trajectories. The results of this study indicated that the maternal depressive levels of a high risk group had increased significantly over the past 5 years. The predictors for these developmental trajectories of maternal depressive symptoms were as follows; birth order, maternal prenatal depressive levels, self-esteem, marital satisfaction, parenting stress and the level of family crisis experienced by the high risk group.