• Title/Summary/Keyword: Preliminary Response

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Preliminary Study of Neuronal Response to Dose Distribution of Radiation with MR Spectroscopy

  • Ahn, Seung-Do;Yi, Byoung-Young;Lee, Jung-Hee
    • Proceedings of the Korean Biophysical Society Conference
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    • 2002.06b
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    • pp.25-26
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    • 2002
  • The goal of radiation therapy is to maximize the tumor dose and to minimize the dose of normal tissue. In order to achieve this goal, the new radiation therapy techniques such as three dimensional conformal therapy or intensity modulated radiation therapy has been developed and tried to clinical application. The relationship between radiation dose and normal tissue response is an interesting subject in the radiation therapy field.(omitted)

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Acrosswind aeroelastic response of square tall buildings: a semi-analytical approach based of wind tunnel tests on rigid models

  • Venanzi, I.;Materazzi, A.L.
    • Wind and Structures
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    • v.15 no.6
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    • pp.495-508
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    • 2012
  • The present paper is focused on the prediction of the acrosswind aeroelastic response of square tall buildings. In particular, a semi-analytical procedure is proposed based on the assumption that square tall buildings, for reduced velocities corresponding to operational conditions, do not experience vortex shedding resonance or galloping and fall in the range of positive aerodynamic damping. Under these conditions, aeroelastic wind tunnel tests can be unnecessary and the response can be correctly evaluated using wind tunnel tests on rigid models and analytical modeling of the aerodynamic damping. The proposed procedure consists of two phases. First, simultaneous measurements of the pressure time histories are carried out in the wind tunnel on rigid models, in order to obtain the aerodynamic forces. Then, aeroelastic forces are analytically evaluated and the structural response is computed through direct integration of the equations of motion considering the contribution of both the aerodynamic and aeroelastic forces. The procedure, which gives a conservative estimate of the aeroelastic response, has the advantage that aeroelastic tests are avoided, at least in the preliminary design phase.

Large-scale Seismic Response Analysis of Super-high-rise Steel Building Considering Soil-structure Interaction using K computer

  • Miyamura, Tomoshi;Akiba, Hiroshi;Hori, Muneo
    • International Journal of High-Rise Buildings
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    • v.4 no.1
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    • pp.75-83
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    • 2015
  • In the present study, the preliminary results of a large-scale seismic response analysis of a super-high-rise steel frame considering soil-structure interaction are presented. A seismic response analysis under the excitation of the JR Takatori record of the 1995 Hyogoken-Nanbu earthquake is conducted. Precise meshes of a 31-story super-high-rise steel frame and a soil region, which are constructed completely of hexahedral elements, are generated and combined. The parallel large-scale simulation is performed using K computer, which is one of the fastest supercomputers in the world. The results are visualized using an offline rendering code implemented on K computer, and the feasibility of using a very fine mesh of solid elements is investigated. The computation performance of the analysis code on K computer is also presented.

A Study on the Vibration of Characteristics of 3-Dimension Submerged Vehicle in Consideration of Fluid-Structure Interaction (유체력을 고려한 3차원 수중압력선체의 진동특성에 관한 연구)

  • 손충렬;황인하;이강수
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2000.04a
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    • pp.81-88
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    • 2000
  • Unlike structures in the air, the vibration analysis of a submerged or floating structure such as offshore structures or ships is possible only when the fluid-structure interaction is understood, as the whole or part of the structure is in contact with water. Specially, the importance of the added mass is not necessary to say like the submerged vehicle, all of the hull body, is positioned in the water. This paper introduce two method to find natural frequency in consideration of fluid-structure modal coupled vibration analysis. The purpose of this study is to analyze of the vibration characteristic of submerged vehicle to obtain the anti-vibration design data, which could be used in the preliminary design stage data. Underwater pressure hull of submerged vehicle is used as the model of this study. The F.E.M model is meshed by shell and beam element. Also, considering of the inner hull weight, mass element is distributed in the direction of hull length. Numerical calculations are accomplished using the commercial B.E.M code. The characteristics of natural frequency(eigenvalues), mode shape(eigenvectors) and frequency-displacement response are analyzed. The results of this study will be used as the useful design data in preliminary anti-vibration design stage.

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Dependency of COD on ground motion intensity and stiffness distribution

  • Aschheim, Mark;Maurer, Edwin;Browning, JoAnn
    • Structural Engineering and Mechanics
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    • v.27 no.4
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    • pp.425-438
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    • 2007
  • Large changes in stiffness associated with cracking and yielding of reinforced concrete sections may be expected to occur during the dynamic response of reinforced concrete frames to earthquake ground shaking. These changes in stiffness in stories that experience cracking might be expected to cause relatively large peak interstory drift ratios. If so, accounting for such changes would add complexity to seismic design procedures. This study evaluates changes in an index parameter to establish whether this effect is significant. The index, known as the coefficient of distortion (COD), is defined as the ratio of peak interstory drift ratio and peak roof drift ratio. The sensitivity of the COD is evaluated statistically for five- and nine-story reinforced concrete frames having either uniform story heights or a tall first story. A suite of ten ground motion records was used; this suite was scaled to five intensity levels to cause varied degrees of damage to the concrete frame elements. Ground motion intensity was found to cause relatively small changes in mean CODs; the changes were most pronounced for changes in suite scale factor from 0.5 to 1 and from 1 to 4. While these changes were statistically significant in several cases, the magnitude of the change was sufficiently small that values of COD may be suggested for use in preliminary design that are independent of shaking intensity. Consequently, design limits on interstory drift ratio may be implemented by limiting the peak roof drift in preliminary design.

Development and Validation of an Instrument to Measure High School Students' Disaster Safety Awareness

  • Lee, Soon-Beom;Kong, Ha-Sung
    • International Journal of Internet, Broadcasting and Communication
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    • v.13 no.4
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    • pp.154-168
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    • 2021
  • The purpose of this study is to develop and validate the disaster safety awareness scale for high school students. For this purpose, the previously developed disaster safety awareness scale and related prior research was analyzed. Questionnaire data was collected from March 22 to May 25, 2021 from 1054 students (male: 569, female: 485) in the first, second, and third grades of 5 high schools in 3 cities. Through the process of revising, supplementing, and reviewing the items extracted through preliminary research and preliminary test together with experts and students, a final disaster safety awareness scale consisting of 24 items was developed. This scale consists of four sub-factors: 'disaster prevention', 'disaster response A', 'disaster response B', and 'disaster recovery'. Good reliability and validity were secured through exploratory and confirmatory analyses. The significance of this study is that it laid a basic and objective foundation for high school students' disaster safety awareness research by developing a validated scale in a situation where the development of disaster safety awareness scales for high school students was still insufficient. It can be used as useful data for fire safety education as well as a psychological measurement tool for fostering fire safety awareness.

Preliminary Design Procedure of MR Dampers for Controlling Seismic Response of Building Structures (건축구조물의 지진응답제어를 위한 MR 감쇠기 예비설계절차)

  • Lee, Sang-Hyun;Min, Kyung-Won;Lee, Roo-Jee;Kim, Joong-Koo
    • Journal of the Earthquake Engineering Society of Korea
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    • v.8 no.5 s.39
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    • pp.55-64
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    • 2004
  • In this paper, the preliminary design procedure of magnetorheological (MR) dampers is developed for controlling the building response induced by seismic excitation. The dynamic characteristics and control effects of the modeling methods of MR dampers such as Bingham, biviscous, hysteretic biviscous, simple Bouc?Wen, Bouc?Wen with mass element, and phenomenological models are investigated. Of these models, hysteretic biviscous model which is simple and capable describing the hysteretic characteristics, is used for numerical studies. The capacity of MR damper is determined as a portion of not the building weight but the lateral restoring force. A method is proposed for optimal placement and number of MR dampers, and its effectiveness is verified by comparing it with the simplified sequential search algorithm. Numerical results indicate that the capacity, number and the placement can be reasonably determined using the proposed design procedure.

Short-course versus long-course neoadjuvant chemoradiotherapy in patients with rectal cancer: preliminary results of a randomized controlled trial

  • Aghili, Mahdi;Khalili, Nastaran;Khalili, Neda;Babaei, Mohammad;Farhan, Farshid;Haddad, Peiman;Salarvand, Samaneh;Keshvari, Amir;Fazeli, Mohammad Sadegh;Mohammadi, Negin;Ghalehtaki, Reza
    • Radiation Oncology Journal
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    • v.38 no.2
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    • pp.119-128
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    • 2020
  • Purpose: Colorectal cancer is becoming an increasing concern in the middle-aged population of Iran. This study aimed to compare the preliminary results of short-course and long-course neoadjuvant chemoradiotherapy treatment for rectal cancer patients. Materials and Methods: In this clinical trial we recruited patients with rectal adenocarcinoma located from 5 cm to 15 cm above the anal verge. Patients in group I (short-course) received three-dimensional conformational radiotherapy with a dose of 25 Gy/5 fractions in 1 week plus concurrent XELOX regimen (capecitabine 625 mg/㎡ from day 1-5 twice daily and oxaliplatin 50 mg/㎡ on day 1 once daily). Patients in group II (long-course) received a total dose of 50-50.4 Gy/25-28 fractions for 5 to 5.5 weeks plus capecitabine 825 mg/㎡ twice daily. Both groups underwent consolidation chemotherapy followed by delayed surgery at least 8 weeks after radiotherapy completion. The pathological response was assessed with tumor regression grade. Results: In this preliminary report on complications and pathological response, 66 patients were randomized into two study groups. Mean duration of radiotherapy in the group II (long-course) was 5 ± 1 days (range, 5 to 8 days) and 38 ± 6 days (range, 30 to 58 days). The median follow-up was 18 months. Pathological complete response was achieved in 32.3% and 23.1% of patients in the shortcourse and long-course groups, respectively (p = 0.558). Overall, acute grade 3 or higher treatment-related toxicities occurred in 24.2% and 22.2% of patients in group I and II, respectively (p = 0.551). No acute grade 4 or 5 adverse events were observed in either group except one grade 4 hematologic toxicity that was seen in group II. Within one month of surgery, no significant difference was seen regarding grade ≥3 postoperative complications (p = 0.333). Conclusion: For patients with rectal cancer located at least 5 cm above the anal verge, short-course radiotherapy with concurrent and consolidation chemotherapy and delayed surgery is not different in terms of acute toxicity, postoperative morbidity, complete resection, and pathological response compared to long-course chemoradiotherapy.

Effect of structure configurations and wind characteristics on the design of solar concentrator support structure under dynamic wind action

  • Kaabia, Bassem;Langlois, Sebastien;Maheux, Sebastien
    • Wind and Structures
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    • v.27 no.1
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    • pp.41-57
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    • 2018
  • Concentrated Solar Photovoltaic (CPV) is a promising alternative to conventional solar structures. These solar tracking structures need to be optimized to be competitive against other types of energy production. In particular, the selection of the structural parameters needs to be optimized with regards to the dynamic wind response. This study aims to evaluate the effect of the main structural parameters, as selected in the preliminary design phase, on the wind response and then on the weight of the steel support structure. A parametric study has been performed where parameters influencing dynamic wind response are varied. The study is performed using a semi-deterministic time-domain wind analysis method. Unsteady aerodynamic model is applied for the shape of the CPV structure collector at different configurations in conjunction with a consistent mass-spring-damper model with the corresponding degrees of freedom to describe the dynamic response of the system. It is shown that, unlike the static response analysis, the variation of the peak wind response with many structural parameters is highly nonlinear because of the dynamic wind action. A steel structural optimization process reveals that close attention to structural and site wind parameters could lead to optimal design of CPV steel support structure.

A Study on International Convention on Oil Pollution Preparedness, Response and Co-operation for Domestic Legislation (유류오염 대비.대응 및 협력에 관한 국제협약의 입법론적 고찰)

  • 황석갑
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 1998.04a
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    • pp.128-155
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    • 1998
  • Recently , our govermment makes effort to prevent oil pollutin at sea. However, we still remain vulnerable to oil spills near the borders it shares with China, Japan and Russia due to legal and administrative impedements associated with cross-boundary spill response activity. For a reasonalbel domestic implementation of the International Conventions related oil pollution , our government has already accepted several Conventions such as SOLA 74 , MARPOL 73/78, STCW 78, CLC 69 and FC 71 except an International Convention on Oil Pollution Preparedness, Response and Co-operation, 1990. Therefore, this paper explores comprehesive legal structure applicable for future domestic legislation of international preparedness , response and co-operation on the base of the Convention, 1990. And also preliminary legal researches are to be done for earlier acceptance of the Convention, 1990. Consequently it is necessary to prepare natinal contigency plan and bilateral or multilateral agreements for oil pollution preparedness and response with adjacent natinos prior to acceptance of the Convention . In addition , it is also necessary that neighboring nations must take action to facilitate cross-boundary activities by responders providing responder immunity protection and by removing potential impediments to response activities by appropriate law and other requirements such as customs , immigration , and safety training.

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