• Title/Summary/Keyword: Prediction-Based

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Feature Selection with Ensemble Learning for Prostate Cancer Prediction from Gene Expression

  • Abass, Yusuf Aleshinloye;Adeshina, Steve A.
    • International Journal of Computer Science & Network Security
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    • v.21 no.12spc
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    • pp.526-538
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    • 2021
  • Machine and deep learning-based models are emerging techniques that are being used to address prediction problems in biomedical data analysis. DNA sequence prediction is a critical problem that has attracted a great deal of attention in the biomedical domain. Machine and deep learning-based models have been shown to provide more accurate results when compared to conventional regression-based models. The prediction of the gene sequence that leads to cancerous diseases, such as prostate cancer, is crucial. Identifying the most important features in a gene sequence is a challenging task. Extracting the components of the gene sequence that can provide an insight into the types of mutation in the gene is of great importance as it will lead to effective drug design and the promotion of the new concept of personalised medicine. In this work, we extracted the exons in the prostate gene sequences that were used in the experiment. We built a Deep Neural Network (DNN) and Bi-directional Long-Short Term Memory (Bi-LSTM) model using a k-mer encoding for the DNA sequence and one-hot encoding for the class label. The models were evaluated using different classification metrics. Our experimental results show that DNN model prediction offers a training accuracy of 99 percent and validation accuracy of 96 percent. The bi-LSTM model also has a training accuracy of 95 percent and validation accuracy of 91 percent.

Analysis of the Limitations of the Existing Subsidence Prediction Method Based on the Subsidence Measurement Data and Suggestions for Improvement Method Through Weighted Nonlinear Regression Analysis (기존 계측 기반 침하 예측 이론식 한계점 도출 및 가중 비선형 회귀분석을 통한 침하 예측 개선방안 제시)

  • Kwak, Tae-Young;Hong, Seongho;Lee, Ju-Hyung;Woo, Sang-Inn
    • Journal of the Korean Geotechnical Society
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    • v.38 no.12
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    • pp.103-112
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    • 2022
  • The existing subsidence prediction method based on the measurement data were confirmed in this study through literature research. It was confirmed that the hyperbolic method and the Asaoka method showed high accuracy, while the other prediction methods showed significantly low accuracy. Based on the analysis results, the limitations of the existing prediction equations were derived, and the improvement method of the settlement prediction equations was suggested. In this study, a weighted nonlinear regression analysis method that gives higher weight to the later data was proposed to improve the existing hyperbolic method.

A Signal-Level Prediction Scheme for Rain-Attenuation Compensation in Satellite Communication Linkes (위성 통신 링크에서 강우 감쇠 보상을 위한 신호 레벨 예측기법)

  • 임광재;황정환;김수영;이수인
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.25 no.6A
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    • pp.782-793
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    • 2000
  • This paper presents a simple dynamical prediction scheme of the signal level which is attenuated and varied due to rain fading in satellite communication links using above 10GHz frequency bands. The proposed prediction scheme has four functional blocks for discrete-time low-pass filtering, slope-based prediction, mean-error correction and hybrid fixed/variable prediction margin allocation. Through simulations using Ka-band attenuation data obtained from the data measured over Ku-band by frequency-scaling, it is shown that the slope-based prediction with the mean-error correction has as small standard deviation of prediction error as below 1 dB, and that the error is about 1.5 to 2.5 times as small as that without the mean-error correction. The hybrid prediction margin allocation requires smaller average margin than those of both fixed and variable methods.

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Software Quality Classification using Bayesian Classifier (베이지안 분류기를 이용한 소프트웨어 품질 분류)

  • Hong, Euy-Seok
    • Journal of Information Technology Services
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    • v.11 no.1
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    • pp.211-221
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    • 2012
  • Many metric-based classification models have been proposed to predict fault-proneness of software module. This paper presents two prediction models using Bayesian classifier which is one of the most popular modern classification algorithms. Bayesian model based on Bayesian probability theory can be a promising technique for software quality prediction. This is due to the ability to represent uncertainty using probabilities and the ability to partly incorporate expert's knowledge into training data. The two models, Na$\ddot{i}$veBayes(NB) and Bayesian Belief Network(BBN), are constructed and dimensionality reduction of training data and test data are performed before model evaluation. Prediction accuracy of the model is evaluated using two prediction error measures, Type I error and Type II error, and compared with well-known prediction models, backpropagation neural network model and support vector machine model. The results show that the prediction performance of BBN model is slightly better than that of NB. For the data set with ambiguity, although the BBN model's prediction accuracy is not as good as the compared models, it achieves better performance than the compared models for the data set without ambiguity.

Development and application of a floor failure depth prediction system based on the WEKA platform

  • Lu, Yao;Bai, Liyang;Chen, Juntao;Tong, Weixin;Jiang, Zhe
    • Geomechanics and Engineering
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    • v.23 no.1
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    • pp.51-59
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    • 2020
  • In this paper, the WEKA platform was used to mine and analyze measured data of floor failure depth and a prediction system of floor failure depth was developed with Java. Based on the standardization and discretization of 35-set measured data of floor failure depth in China, the grey correlation degree analysis on five factors affecting the floor failure depth was carried out. The correlation order from big to small is: mining depth, working face length, floor failure resistance, mining thickness, dip angle of coal seams. Naive Bayes model, neural network model and decision tree model were used for learning and training, and the accuracy of the confusion matrix, detailed accuracy and node error rate were analyzed. Finally, artificial neural network was concluded to be the optimal model. Based on Java language, a prediction system of floor failure depth was developed. With the easy operation in the system, the prediction from measured data and error analyses were performed for nine sets of data. The results show that the WEKA prediction formula has the smallest relative error and the best prediction effect. Besides, the applicability of WEKA prediction formula was analyzed. The results show that WEKA prediction has a better applicability under the coal seam mining depth of 110 m~550 m, dip angle of coal seams of 0°~15° and working face length of 30 m~135 m.

Travel Time Prediction Algorithm using Rule-based Classification on Road Networks (규칙-기반 분류화 기법을 이용한 도로 네트워크 상에서의 주행 시간 예측 알고리즘)

  • Lee, Hyun-Jo;Chowdhury, Nihad Karim;Chang, Jae-Woo
    • The Journal of the Korea Contents Association
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    • v.8 no.10
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    • pp.76-87
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    • 2008
  • Prediction of travel time on road network is one of crucial research issue in dynamic route guidance system. A new approach based on Rule-Based classification is proposed for predicting travel time. This approach departs from many existing prediction models in that it explicitly consider traffic patterns during day time as well as week day. We can predict travel time accurately by considering both traffic condition of time range in a day and traffic patterns of vehicles in a week. We compare the proposed method with the existing prediction models like Link-based, Micro-T* and Switching model. It is also revealed that proposed method can reduce MARE (mean absolute relative error) significantly, compared with the existing predictors.

Reliability Prediction Based Reliability Growth Management : Case Study of Surveillance System (신뢰도 예측 기반 신뢰도 성장 관리 : 감시체계 사례)

  • Kim, SB;Park, WJ;You, JW;Lee, JK;Yong, HY
    • Journal of Korean Society for Quality Management
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    • v.47 no.1
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    • pp.187-198
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    • 2019
  • Purpose: In this study, a reliability prediction based reliability growth management is suggested especially for the early development phase of a system and the case study of surveillance system is given. Methods: The proposed reliability prediction based reliability growth management procedures consists of 7 Steps. In Step 1, the stages for reliability growth management are classified according to the major design changes. From Step 2 to Step 5, system reliability is predicted based on reliability structures and the predicted reliabilities of subsystems (Level 2) and modules (Level 3). At each stage, by comparing the predicted system reliability with that of the previous stage, the reliability growth of the system is checked in Step 6. In Step 7, when the predicted value of sustem reliability does not satisfy the reliability goal, some design alternatives are considered and suggested to improve the system reliability. Results: The proposed reliability prediction based reliability growth management can be an efficient alternative for managing reliability growth of a system in its early development phase. The case study shows that it is applicable to weapon system such as a surveillance system. Conclusion: In this study, the procedures for a reliability prediction based reliability growth management are proposed to satisfy the reliability goal of the system efficiently. And it is expected that the use of the proposed procedures would reduce, in the test and evaluation phase, the number of corrective actions and its cost as well.

ARMA-based data prediction method and its application to teleoperation systems (ARMA기반의 데이터 예측기법 및 원격조작시스템에서의 응용)

  • Kim, Heon-Hui
    • Journal of Advanced Marine Engineering and Technology
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    • v.41 no.1
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    • pp.56-61
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    • 2017
  • This paper presents a data prediction method and its application to haptic-based teleoperation systems. In general, time delays inevitably occur during data transmission in a network environment, which degrades the overall performance of haptic-based teleoperation systems. To address this situation, this paper proposes an autoregressive moving average (ARMA) model-based data prediction algorithm for estimating model parameters and predicting future data recursively in real time. The proposed method was applied to haptic data captured every 5 ms while bilateral haptic interaction was carried out by two users with an object in a virtual space. The results showed that the prediction performance of the proposed method had an error of less than 1 ms when predicting position-level data 100 ms ahead.

Assessment of Dryout Heat Flux Correlations for Particle Beds

  • Jeong, Yong-Hoon;Baek, Won-Pil;Chang, Soon-Heung
    • Proceedings of the Korean Nuclear Society Conference
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    • 1997.05a
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    • pp.362-367
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    • 1997
  • To assess the coolability of particle bed, which is formed in reactor cavity, it is important to assess the prediction capabilities of Dryout Heat flux correlations. The existing DHF correlations (Sowa et al., Dhir-Catton (a), Dhir-Catton (b), Hardee-Nilson, Ostesen, Shires-Stevens, Lipinski, Jones et al., Dhir-Barleon, Theofanous-Saito, Henry-Fauske) for particle beds are assessed using developed DHF database. Eleven DHF correlations are chosen for assessment based on literature survey. Among them, five are based on flooding correlation, which are used for chemical engineering and others are based on conservation equations. The parameters in DHF correlations are directly substituted into correlations. Totally 202 data are classified into 6 groups based on bed thickness and particle diameter. In each group, prediction capabilities of correlations are assessed and shown by standard deviation and root mean square (RMS) error. Prediction capability of each correlation depends on the data group and none of correlations shows best prediction capability on entire groups. According to present study, even if those correlations show poor prediction capability, Lipinski correlation is best correlation considering entire groups.

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Application of Physiologically Based Pharmacokinetic (PBPK) Modeling in Prediction of Pediatric Pharmacokinetics (생리학 기반 약물동태(PBPK, Physiologically Based Pharmacokinetic) 모델링을 이용한 소아 약물 동태 예측 연구)

  • Shin, Na-Young;Park, Minho;Shin, Young Geun
    • YAKHAK HOEJI
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    • v.59 no.1
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    • pp.29-39
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    • 2015
  • In recent years, physiologically based pharmacokinetic (PBPK) modeling has been widely used in pharmaceutical industries as well as regulatory health authorities for drug discovery and development. Several application areas of PBPK have been introduced so far including drug-drug interaction prediction, transporter-mediated interaction prediction, and pediatric PK prediction. The purpose of this review is to introduce PBPK and illustrates one of its application areas, particularly pediatric PK prediction by utilizing existing adult PK data and in vitro data. The evaluation of the initial PBPK for adult was done by comparing with experimental PK profiles and the scaling from adult to pediatric was conducted using age-related changes in size such as tissue compartments, and protein binding etc. Sotalol and lorazepam were selected in this review as model drugs for this purpose and were re-evaluated using the PBPK models by GastroPlus$^{(R)}$. The challenges and strategies of PBPK models using adult PK data as well as appropriate in vitro assay data for extrapolating pediatric PK at various ages were also discussed in this paper.