• Proceedings of the Korean Society of Precision Engineering Conference
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• 2012.05a
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• pp.1245-1246
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• 2012

• Current Optics and Photonics
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• v.3 no.2
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• pp.150-153
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• 2019

Larynx cancer is a potentially terminal and severe type of neck and head cancer in which malignant cells start to grow and spread upwards in the larynx, or voice box. Smoking tobacco, drinking hot beverages and drinking alcohol are the main risk factors for these tumors. In this study, we aimed to develop a precise, accurate and rapid chemometrics assisted Raman spectroscopy method for diagnosis of larynx cancer in deparaffinized tissue samples. In the proposed method, samples were deparaffinized and 20 microns of each tissue were located on a coverslip. Both healthy (n = 13) and cancerous tissues (n = 13) were exposed to a Raman laser (785 nm) and excitations were recorded between wavenumbers of $50{\sim}1500cm^{-1}$. An Orthogonal Partial Least Square algorithm was applied to evaluate the Raman spectrum obtained. Sensitivity and specificity of the proposed method is high enough with the aid of Principal Component Analysis (PCA) to test the whole model. Healthy and cancerous tissues were accurately and precisely clustered. A rapid, easy and precise diagnosis algorithm was developed for larynx cancer. By this method, some useful data about differences in biomolecules of each group (phospholipids, amides, tyrosine, phenylalanine collagen etc.) was also obtained from the spectra. It is claimed that the optimized method has a great potential for clustering and separating tumor tissues from healthy ones. This novel, rapid, precise and objective diagnosis method may be an alternative for the conventional methods in literature for diagnosis of larynx cancer.

• Proceedings of the KSR Conference
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• 2010.06a
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• pp.540-545
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• 2010

As the urban railroad durability period law has revised on march 19, 2009, the life cycle of urban railroad cars has lengthened to 40 years for the longest period. It seems to be attributed to the development of railroad car making technique along with their durability being longer thanks to the quality improvement of their materials and parts. As the stability of urban railroad cars is directly linked to the safety of passengers, safety should be considered first, and more precise examination is necessary for endurance extension. Hereupon, the rolling stocks with their durability near expiration should get precise diagnosis following the revised "RDG for urban railroad cars" This study aims to suggest a diagnosis method for the institute and the urban railroad operating body which enforce the revised diagnosis, through the case of Busan transportation corporation which firstly started the revised diagnosis after the durability related law has been revised.

• Journal of the Korea institute for structural maintenance and inspection
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• v.25 no.3
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• pp.85-91
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• 2021

Type 1 and type 2 buildings must regularly conduct precise safety inspections and precise safety diagnosis for the safety and maintenance of facilities, and the safety grade of the building is determined according to the results of the implementation. In addition, the cycle of inspection and diagnosis is determined according to the safety grade of the building. In order to determine the safety grade of the building, a precise safety inspection conducts condition evaluation, and a precise safety diagnosis conducts condition evaluation and safety evaluation. Therefore, since the inspection and diagnosis cycle is determined according to the safety grade of the building, the condition evaluation and safety evaluation must be precise. However, in the case of member unit evaluation, which is the first step in evaluating the current condition, the evaluation grade is determined by using the representative value of the measurement result, and this may result in an error in the evaluation grade. To solve this problem, this study analyzed evaluation criteria for each evaluation item and presented evaluation criteria using inequalities to respond to measurement results and evaluation scores. In addition, we present a functional formula that can reflect performance scores for each evaluation item.

• Journal of the Earthquake Engineering Society of Korea
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• v.22 no.3
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• pp.169-174
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• 2018

A total of 594 reservoirs (17%), which are managed by KRC, equipped with earthquake-resistant facilities whereas remaining ones did not. In addition, reservoirs were placed without the effect of geological structures (i.e., fault and lineament). Therefore, development on technique for alleviating the potential hazards by natural disasters along faults and lineaments has required. In addition, an effective reinforcement guideline related to the geological vulnerabilities around reservoirs has required. The final goal of this study is to suggest the effective maintenance for the safety of earth fill dams. A radius 2 km, based on the center of the reservoir in the study area was set as the range of vulnerability impacts of each reservoir. Seismic design, precise safety diagnosis, seismic influence and geological structure were analyzed for the influence range of each reservoir. To classify the vulnerability of geological disasters according to the fault distribution around the reservoir, evaluation index of seismic performance, precise safety diagnosis, seismic influence and geological structure were also developed for each reservoir, which were a component of the vulnerability assessment of geological disasters. As a result, the reservoir with the highest vulnerability to geological disasters in the pilot district was analyzed as Kidong reservoir with an evaluation index of 0.364. Within the radius of 100km from the epicenter of the Pohang earthquake, the number of agricultural infrastructure facilities subject to urgent inspections were 1,180 including reservoirs, pumping stations and intakes. Four reservoirs were directly damaged by earthquake among 724 agricultural reservoirs. As a result of the precise inspection and electrical resistivity survey of the reservoir after the earthquake, it was reported that cracks on the crest of reservoirs were not a cause of concern. However, we are constantly monitoring the safety of agricultural facilities by Pohang aftershocks.

• The Journal of the Korean dental association
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• v.54 no.9
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• pp.684-691
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• 2016

The odontogenic cutaneous fistula in facial area is uncommon but, well defined disease. It is difficult to diagnose from the dental origin of cutaneous sinus tract. Most patients may visit to the dermatologists or general hospital without cause of disease. They usually be treated by repeated surgical excisions, biopsies, and antibiotic medications, but suffered from recurrences. We studied odontogenic cutaneous fistula through retrospective study in Jeju Special Self-Governing Province between 1 January 2009 and 12 December 2015. There were 3 males, 5 females from 14 to 78 years old with an average age of 50.4 years old. Only 2 patients felt the toothache, others didn't detect it. They suffered from recurrences and repeated treatments for 3 to 11 months with an average period of 7.9 months. They visited average 2.8 hospitals before a precise diagnosis in a dental clinic. All cases were fully healed endodontic treatment or extraction of origin teeth without recurrences. In conclusion, the cause of cutaneous fistula in facial area can be odontogenic. If dentists or doctors diagnose a patient with cutaneous fistula on face, they should check dental problems or take x-ray views for precise diagnosis. It could be helpful for differential diagnosis.

• Journal of Gastric Cancer
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• v.23 no.3
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• pp.410-427
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• 2023

Recent advances in artificial intelligence (AI) have provided novel tools for rapid and precise pathologic diagnosis. The introduction of digital pathology has enabled the acquisition of scanned slide images that are essential for the application of AI. The application of AI for improved pathologic diagnosis includes the error-free detection of potentially negligible lesions, such as a minute focus of metastatic tumor cells in lymph nodes, the accurate diagnosis of potentially controversial histologic findings, such as very well-differentiated carcinomas mimicking normal epithelial tissues, and the pathological subtyping of the cancers. Additionally, the utilization of AI algorithms enables the precise decision of the score of immunohistochemical markers for targeted therapies, such as human epidermal growth factor receptor 2 and programmed death-ligand 1. Studies have revealed that AI assistance can reduce the discordance of interpretation between pathologists and more accurately predict clinical outcomes. Several approaches have been employed to develop novel biomarkers from histologic images using AI. Moreover, AI-assisted analysis of the cancer microenvironment showed that the distribution of tumor-infiltrating lymphocytes was related to the response to the immune checkpoint inhibitor therapy, emphasizing its value as a biomarker. As numerous studies have demonstrated the significance of AI-assisted interpretation and biomarker development, the AI-based approach will advance diagnostic pathology.

• The Korean Journal of Cytopathology
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• v.18 no.1
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• pp.55-61
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• 2007

Once diagnosed as "cell paucity"or "atypia" by the cytospin (CS) preparation, this CS preparation does not secure a precise diagnosis by repeated testing alone. Although the ThinPrep (TP) preparation is acknowledged to show increased cellularity, performing the screening tests for the cases that have enough cellularity, according to CS, raises issues for the cost-effectiveness. To obtain a more precise diagnosis through increasing the cellularity by performing TP, we selected the cases that were diagnosed as "cell paucity" or "atypia" by CS, but they required a more precise diagnosis, and the samples were processed via both CS and TP to compare the results. 11 patients diagnosed as "cell paucity" and 22 patients diagnosed as "atypia" by CS participated in this study. When the detection rate of atypical cells in both preparations with repeated urine cytology was compared, the overall detection rate of TP (16cases, 48.5%) was superior than that of CS (11cases, 33.3%), with statistical significance. The cellularity of both preparations was compared on repeated urine cytology; the general cellularity of TP (29cases, 87.9%) was higher than that of CS (20cases, 60.6%), but there was no statistical significance. Particularly, we repeated the TP for the 1 case that was diagnosed as "atypia" and we performed polyoma virus immunohistochemical staining, which confirmed polyoma virus. In conclusion, we can avoid obtaining negative diagnosis from cases with uncertain "atypia" or "cell paucity" by performing repeated TP testing.

• Journal of Korean Neurosurgical Society
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• v.48 no.6
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• pp.473-479
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• 2010

A cervical radiculopathy is the most common symptom of cervical degenerative disease and its natural course is generally favorable. With a precise diagnosis using appropriate tools, the majority of patients will respond well to conservative treatment. Cervical radiculopathy with persistent radicular pain after conservative treatment and progressive or profound motor weakness may require surgery. Options for surgical management are extensive. Each technique has strengths and weaknesses, so the choice will depend on the patient's clinical profile and the surgeon's judgment.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2012.05a
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• pp.194-197
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• 2012

The purpose of the thesis is to develop a module which can measure precise Continuous Cardiac Output(CCO) better than existing equipments for the critical cardiopulmonary patient diagnosis purpose. This module enables more precise and effective diagnosis and treatment for the patient by compensating old method which injected cold liquid to inside of heart to measure the CCO.