STATEMENT OF PROBLEM: The discoloration of anterior teeth restoration is one of the material problems demanding retreatment. OBJECTIVES: To evaluate the color stability and affecting factors on esthetic restorative materials when subjected to accelerated aging. MATERIAL AND METHODS: This study was conducted using porcelain disks (IPS Empress 2-glazed, IPS Empress 2-polished), direct restorative resin disks (SYNERGY Duo) and indirect restorative resin disks (Sinfony, TESCERA ATL). Accelerated aging was done by precipitating the specimens in 38.C distilled water and irradiating with xenon light, and the total irradiation was 397.98 KJ/mm. Color and microhardness change of the specimens were measured before accelerated aging and after 100 hours, 200 hours and 300 hours of accelerated aging, and Surface of the specimens were examined with SEM before and after 300 hours of accelerated aging. RESULTS: 1. After 300 hours' accelerated aging, a ${\Delta}E$ value was 3.3 or lower in IPS Empress 2-glazed, IPS Empress 2-polished and Sinfony. 2. After 300 hours' accelerated aging, gloss was lost and surface changes including microcracks were observed in TESCERA ATL and SYNERGY Duo, and color changes of them ranged between 3.58 and 6.40 ${\Delta}E$ units. 3. During 300 hours' accelerated aging, the microhardness of surface was increased by 3.21 - 19.64% in all kinds of composites resin. CONCLUSION: After 300 hours' accelerated aging, SEM images IPS Empress 2-glazed, IPS Empress 2-polished and Sinfony showed little morphological change and their color changes were considered to be clinically acceptable. And there was significant correlation between microhardness changes and color changes of composites (P < .05).
Purpose: Experience of chest pain may be different in women from that of men and this discrepancy may cause misdiagnosis of angina contribute to mortality by this disease in women. The purpose of this study was to analyze the characteristics of chest pain and responses to the symptoms in women. Method: A content analysis was conducted with interviewed data obtained from women who underwent the treadmill test Result: Seven major categories were identified from this content analysis: attributes of chest pain; accompanied symptoms; precipitating factors; relief strategies; family support; communication with physicians; and effects of chest pain on their lives. Characteristics of pain were described as heaviness, tightness, heating sensation, tearing, and others. Duration and intensity of pain varied in a wide range. Radiating pain presented in 9 patients, and the locations of radiation were throat, neck, shoulder arm and fingers. Women tended not to respond actively to their chest pain, and didn't get appropriate support either from their family or from their physicians when they reported chest pain. Conclusion: Women express non-typical as well as typical patterns of pain when they experience chest pain. Clinicians have to consider the variability of symptoms when they assess women with suspicions of angina.
Traumatic brain injury(TBI) is generally considered to be a risk factor for psychiatric disorders, especially depression and anxiety disorder. Despite the anxiety disorders are frequent sequelae after traumatic brain injury, the patients have not been payed medical attention and treated by doctors properly. The factors of precipitating and sustaining the anxiety disorders after TBI are brain injury itself, and the patient's or caregiver's response to the disability after TBI. To diagnose and treat them effectively, the knowledge about the mechanisms of and symptoms after TBI have to be needed. Psychiatrist should be a supportive and good listener to the patients who are complaining anxiety symptoms and differentiate whether the psychiatric symptoms are due to TBI or not. Because the TBI patients are very sensitive to drug side effects, doctors have to be familiar with the side effects as well as the mechanisms of action of the common psychotropics.
The recombinant strain P. pastoris GS115-lccC was used to produce laccase with high activity. Factors influencing laccase expression, such as pH, methanol concentration, copper concentration, peptone concentration, shaker rotate speed, and medium volume were investigated. Under the optimal conditions, laccase activity reached 12,344 U/L on day 15. The recombinant enzyme was purified by precipitating and dialyzing to electrophoretic homogeneity, and was estimated to have a molecular mass of about 58 kDa. When guaiacol was the substrate, the laccase showed the highest activity at pH 5.0 and was stable when the pH was 4.5~6.0. The optimal temperature for the laccase to oxidize guaiacol was $60^{\circ}C$, but it was not stable at high temperature. The enzyme could remain stable at $30^{\circ}C$ for 5 days. The recombinant laccase was used to degrade chlorpyrifos in several laccase/mediator systems. Among three synthetic mediators (ABTS, HBT, VA) and three natural mediators (vanillin, 2,6-DMP, and guaiacol), vanillin showed the most enhancement on degradation of chlorpyrifos. Both laccase and vanillin were responsible for the degradation of chlorpyrifos. A higher dosage of vanillin may promote a higher level of degradation of chlorpyrifos, and the 2-step addition of vanillin led to 98% chlorpyrifos degradation. The degradation of chlorpyrifos was faster in the L/V system ($k_{obs}$ = 0.151) than that in the buffer solution ($k_{obs}$ = 0.028).
Park, Cheol;Kang, Hee-Ju;Lee, Ju-Yeon;Kim, Seon-Young;Bae, Kyung-Yeol;Kim, Sung-Wan;Kim, Jae-Min;Shin, Il-Seon;Yoon, Jin-Sang
Anxiety and mood
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v.10
no.1
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pp.24-29
/
2014
Objectives : This study aimed to investigate the associations between physical disorders and prevalent/incident suicidal ideation in a community dwelling older population aged 65 years or over. Methods : 1204 people aged 65 years or over evaluated at baseline. Suicidal ideation was identified using the questions from the community version of the Geriatric Mental State Schedule ("GMS B3"). Reported physical disorders covering 11 common and generally chronic health problems were ascertained. Covariates included were depression, age, gender, years of education, accommodation status, past occupation, and current occupation. Of 1066 without suicidal ideation at baseline, 805 (76%) were followed 2 years later, and incident suicidal ideation was evaluated. Results : Prevalent suicidal ideation was significantly associated with 4 of 11 physical disorders: eyesight problems, persistent cough, heart disease and paralysis or weakness in one leg or arm. Incident suicidal ideation was associated with 3 physical disorders: asthma, high blood pressure and paralysis or weakness in one leg or arm. Both prevalent and incident suicidal ideation were significantly associated with increased number of physical disorders. Conclusions : Certain physical disorders were comorbid and precipitating factors of suicidal ideation in elders. And appropriate intervention and treatment of physical disorders might prevent suicidal ideation in elderly.
The purpose of this study is to evaluate the demographic characteristics, alcohol-related characteristics and personality trends in the participants of Alcoholics Anonymous. We compared the 33 participants of Alcoholics Anonymous maintaining abstinence at least over 6 months with 35 hospitalized alcoholic patients who have never attended Alcoholics Anonymous and 32 normal controls. The personality trend was measured by Catell's 16 Personality Factors Questionnaire. -Korean Version. The results were as follows: 1) In the demographic data, the participants of Alcoholics Anonymous were mainly 40's, graduated from high school, married, unemployed, middle class in economic state, first or second sons. 2) In alcohol related characteristics, age of first drinking was mainly distributed from 15 to 19 years-old. The most common psychosocial and environmental problem as precipitating factor of alcohol consumption was the problem with primary supper group and the second one was occupational. Most of them drank everyday, and admitted one time. 3) In the first stratum sources traits, the participants of Alcoholics Anonymous demonstrated significantly higher score than hospitalized alcoholic Patients, but lower than normal control in C-factor(stableness). They demonstrated significantly higher score than hospitalized alcoholic patients and normal controls in O-factor(Guilt-proness) and demonstrated significantly higher score than hospitalized alcoholic patients in Q3-factor(self-control). 4) In the second stratum sources traits, they demonstrated significantly higher score than hospitalized alcoholic patients in EXT-factor(extroversions), and lower score than hospitalized alcoholic patients and normal controls in IND-factor(independence).
Dental caries is the most common disease in the maxillofacial area. There are many factors contributing to its development, but complete understanding and prevention is not fully known. Since the structure of the coronal and root portion of the tooth is different, the remineralization and demineralization process is also known to be different. In this study, by using a partially saturated buffer solution, we created artificial enamel and dentin caries and evaluated mineral loss. A remineralization solution with four different degrees of saturation (degree of saturation ; group 1, 0.268, group 2, 0.309, group 3, 0.339, group 4, 0.390, PH 4.3, F-2ppm) was used on a demineralized specimen. The mineral precipitating quantity and depth was evaluated by using microradiography. Using an atomic force microscope (AFM), hydroxyapatite crystals of normal, demineralized, and remineralized enamel and dentin were evaluated. The results were as follows: 1. As the degree of saturation of the remineralizing solution increased, the mineral precipitation in the enamel was increased. In group 4, mineral precipitation was limited near the surface. 2. As the degree of saturation of the remineralizing solution increased, the mineral precipitation in the dentin was decreased and it occurred in a deeper portion. In group 4, however, mineral precipitation occurred on the surface and its quantity increased. 3. There was a statistically significant interaction between enamel and dentin mineral content changes on specimens treated with remineralization and demineralization solution (demineralization r=0.44, remineralization r=0.44, p<0.05). 4. Demineralized hydroxyapatite crystals showed central and peripheral dissolving and widening of intercrystal spaces under the AFM. 5. In dentin remineralization small crystal precipitation occurred between the large crystals. We conclude that by adjusting acidulated buffer solution's degree of saturation, we can control enamel and dentin remineralization. In addition, the AFM is highly useful in evaluating changes in remineralized and demineralized hydroxyapatite crystals.
Journal of The Korean Society of Clinical Toxicology
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v.2
no.1
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pp.7-11
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2004
Purpose: We would evaluate the cardiovascular manifestations of the patients with acute organophosphate and carbamate poisoning in the emergency department. Methods: This was retrospectively studied with the review of patient's charts, included total 38 patients were admitted during the past two years in the emergency department of Yeungnam university hospital with the diagnosis of organophosphate or carbamate poisoning. Results: Cardiovascular complications were variously developed in many patients. Electrocardiographic findings were as follows; 4 ($10.5\%$) cardiac arrhythmias included 1 cardiac arrest caused by ventricular fibrillation, 14 ($36.8\%$) sinus tachycardias, 3 ($7.9\%$) sinus bradycardias, and 17 ($44.7\%$) normal sinus rhythms. Conduction disturbances were 23 ($60.5\%$) like as prolonged QTc, 4 ($10.5\%$) ST-T changes, 2 (5.3%) first degree AV block, and 3 ($7.9\%$) right bundle branch block were shown. Other cardiovascular complications were 22 ($57.9\%$) hypertensives, 4 ($10.5\%$) hypotensives, 15 ($39.5\%$) tachycardias, 2 ($5.3\%$) bradycardias, 18 ($47.4\%$) hypoxemics, 12 ($31.6\%$) metabolic acidosis, and 9 ($23.7\%$) pulmonary edemas. Sixteen patients ($42.1\%$) needed ventilatory support because of respiratory paralysis. No patients died in hospital and 36 ($94.7\%$) patients were alive-discharged. Conclusion: Cardiovascular complications are variously in patients with acute organophosphate and carbamate poisoning. Especially, some findings included ventricular arrhythmias, QTc prolongation, hypoxemia, acidosis, and blood pressure changes are known as major precipitating factors to increase the mortality. So, intensive support and aggressive treatment are needed in patients shown various cardiovascular manifestations in the emergency department.
Kim, Min-Jun;Park, Il-Jeong;Kim, Dae-Weon;Jung, Hang-Chul
Resources Recycling
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v.28
no.1
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pp.23-31
/
2019
Cementation is one of economical and efficient recycling method precipitating the metal ion in solution by adding another active metal. In this study for optimizing cadmium recovery efficiency, it was performed as a function of the effect of pH, temperature, particle size, and input amount of zinc in 0.1 M $CdSO_4$ solution and Ni-Cd battery leaching solutions, respectively. The particle size of zinc and temperature were key factors for Cd cementation and it was confirmed that the input amount of 2.6 of Zn/Cd ratio using granular-type zinc was optimal condition for selective Cd recovery efficiency at $25^{\circ}C$.
Background: Trigeminal neuralgia is a debilitating craniofacial pain syndrome that is characterized by paroxysms of intense, short-lived electric shock-like pains in the trigeminal nerve distribution. Recently, the presence of triggers has become one of the key diagnostic criteria in the 3rd edition of the International Classification of Headache Disorders. Light touch is the most common trigger, however other non-mechanical triggers, such as cold weather and certain foods, have been thought to provoke trigeminal neuralgia anecdotally. We aimed to characterize the prevalence and characteristics of these atypical triggers. Methods: We conducted a retrospective, cross-sectional study of atypical triggers in trigeminal neuralgia patients seen in a tertiary pain clinic in Singapore. Patients were recruited via clinic records, and study data were identified from physician documentation. Results: A total of 60 patients met the inclusion criteria. Weather triggers were observed in 12 patients (20%), of which five patients (8%) reported strong winds, 4 patients (7%) reported cold temperatures, and 3 patients (5%) reported cold winds as triggers. Fifteen patients (25%) had a specific food trigger, of which 10 patients (17%) reported hard or tough food, 5 patients (8%) reported hot/cold food, 4 patients (7%) reported spicy food, and 2 patients (3%) reported sweet food as triggers. Conclusions: Although trigeminal neuralgia is most commonly triggered by mechanical stimuli, atypical triggers such as cold temperatures and certain foods are seen in a significant proportion of patients. These atypical triggers may share a common pathway of sensory afferent Aδ fiber activation.
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