• International Journal of Control, Automation, and Systems
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• 제5권5호
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• pp.601-605
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• 2007

In this paper, we propose a simple and relative electrode contact monitoring method. By exploiting the power line interference, which is regarded as one of the worst noise sources for bio-potential measurement, the relative difference in electrode impedance can be measured without a current or voltage source. Substantial benefits, including no extra circuit components, no degradation of the body potential driving circuit, and no electrical safety problem, can be achieved using this method. Furthermore, this method can be applied to multi-channel isolated bio-potential measurement systems and home health care devices under a steady measuring environment.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 심포지엄 논문집 정보 및 제어부문
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• pp.469-470
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• 2007

In this paper, we propose a simple and relative electrode contact monitoring method. By exploiting the power line interference, which is regarded as one of the worst noise sources for bio-potential measurement, the relative difference in electrode impedance can be measured without a current or voltage source. Substantial benefits, including no extra circuit components, no degradation of the body potential driving circuit, and no electrical safety problem, can be achieved using this method. Furthermore, this method can be applied to multi-channel isolated bio-potential measurement systems and home health care devices under a steady measuring environment.

• 대한의생명과학회지
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• 제21권1호
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• pp.1-8
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• 2015

Alzheimer's disease is a common form of dementia occurring among the elderly population and can be identified by symptoms such as cognition impairments, memory loss and neuronal dysfunction. Alzheimer's disease was found to be caused by the deposition of $\beta$-amyloid plaques and neurofibrillary tangles. In addition, mutation in the APP (Amyloid precursor protein), Presenilin 1 (PSEN1) and Presenilin 2 (PSEN2) genes were also found to contribute to Alzheimer's disease. Since the potential conformational diagnosis of Alzheimer's disease requires histopathological tests on brain through autopsy, potential early diagnosis still remains challenging. In recent years, several researches have proposed the use of biomarkers for early diagnosis. In cerebrospinal fluid (CSF), $\beta$-amyloid(1-42), phosphorylated-tau and total tau were suggested to be effective biomarkers for Alzheimer's disease diagnosis. However, a single biomarker might not be sufficient for potential diagnosis of Alzheimer's disease. Thus, the use of RNA interference (RNAi) through microRNAs (miRNAs) has been proposed by several researchers for simultaneous analysis of several biomarkers using microarray technology. These miRNA based biomarkers can be analysed from both blood and CSF, but miRNAs from blood are advantageous over CSF as they are non-invasive and simple for collection. Moreover, the RNAi based therapeutics by siRNA (short interference RNA) or shRNA (short hairpin RNA) have also been proposed to be effective in the treatment of Alzheimer's disease. This review describes the promising application of RNAi technology in therapeutics and as a biomarker for both Alzheimer's disease diagnosis and treatment.

• Journal of Communications and Networks
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• 제5권4호
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• pp.344-353
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• 2003

Ultra-wideband (UWB) technology is gaining increasing interest for its potential application to short-range indoor wireless communications. Utilizing ultra-short pulses, UWB baseband transmissions enable rich multipath diversity, and can be demodulated with low complexity receivers. Compliance with the FCC spectral mask, and interference avoidance to, and from, co-existing narrow-band services, calls for judicious design of UWB pulse shapers. This paper introduces pulse shaper designs for UWB radios, which optimally utilize the bandwidth and power allowed by the FCC spectral mask. The resulting baseband UWB systems can be either single-band, or, multi-band. More important, the novel pulse shapers can support dynamic avoidance of narrow-band interference, as well as efficient implementation of fast frequency hopping, without invoking analog carriers.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권8호
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• pp.3435-3454
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• 2016

Device-to-device (D2D) communication is a potential solution to the incessant increase in data traffic on cellular networks. The greatest problem is how to control the interference between D2D users and cellular mobile users, and between D2D users themselves. This paper proposes a solution for this issue by putting the full control privilege in cellular network using the software-defined networking (SDN) concept. A software virtual switch called Open vSwitch and several components are integrated into mobile devices for data forwarding and radio resource mapping, whereas the control functions are executed in the cellular network via a SDN controller. This allows the network to assign radio resources for D2D communication directly, thus reducing interference. This solution also brings out many benefits, including resource efficiency, energy saving, topology flexibility, etc. The advantages and disadvantages of this architecture are analyzed by both a mathematical method and a simple implementation. The result shows that implementation of this solution in the next generation of cellular networks is feasible.

• Asian Pacific Journal of Cancer Prevention
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• 제13권6호
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• pp.2445-2452
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• 2012

RNA interference has created a breakthrough in gene silencing technology and there is now much debate on the successful usage of RNAi based methods in treating a number of debilitating diseases. Cancer is often regarded as a result of mutations in genomic DNA resulting in faulty gene expression. The occurrence of cancer can also be influenced by epigenetic irregularities in the chromatin structure which leads to alterations and mutations in DNA resulting in cancer cell formation. A number of therapeutic approaches have been put forth to treat cancer. Anti cancer therapy often involves chemotherapy targeting all the cells in common, whereby both cancer cells as well as normal cells get affected. Hence RNAi technology has potential to be a better therapeutic agent as it is possible to deactivate molecular targets like specific mutant genes. This review highlights the successful use of RNAi inducers against different types of cancer, thereby paving the way for specific therapeutic medicines.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2001년도 추계학술대회 논문집 Vol.14 No.1
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• pp.569-572
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• 2001

Selective. highly stable determination of epinephrine(adrenalin) was achieved in cyclic voltammetric measurement carried out at electrochemically treated conductive boron-doped diamond electrode. Boron-doped diamond electrodes were prepared on single crystal Si wafers by microwave plasma chemical vapor deposition and $B_{2}O_{3}$ was dissolved in acetone/methanol(9:1) mixture solution so that the B/C weight ratio ca. $10^{4}ppm$. Epinephrine is a kind of catecholamines, which secreted from adrenal marrow cells. The serious problem to detection of epinephrine is the interference phenomena of electroactive constituent. including AA. In this study. electrochemical treatment of BDD was carried out to discriminate between epinephrine and AA responses. Experimental results showed that the peak potential of AA oxidation shift to the positive direction and the oxidation peak of epinephrine was unchanged. The effect of electrochemical treatment was maintained up to 40hrs.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.72-73
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• 1998

A new method for enzyme immobilization has been developed to remove interference by potential interferents in body fluids. Instead of using electron mediators, we chose direct hydrogen peroxide measurement route. Extremely hydrogen peroxide-selective polymer was coated as an inner membrane to exclude interferents and then glucose oxidase(GOx) was entrapped by electropolymerization of inert monomers. There was no solvent casting step throughout the whole fabrication procedure but all membranes on Pt-Ir electrode were formed by electropolymerization. Thus, membrane thickness, quantity of enzyme loaded and can be controlled by electrochemical parameters. As a result, reproducibility of biosensor characteristics becomes remarkably improved in terms of mass production.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2009년도 춘계 학술발표회
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• pp.961-965
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• 2009

Using much electric resistivity survey to design or preservation administration of facilities. However, By survey method that electric resistivity survey grasps special quality in base by potential difference creating artificial current in underground, Is influenced in electric resistance propensitys of various underground utilities in base. This Study selects dam 1 place that could grasp well underground situation and studied electricity interference effect by effect of underground utilities. Grasp underground utilities of dam interior, and control and observed accuracy with survey wave because various pole space. Through this Study, wish to present survey method of electric resistivity survey at design or survey of preservation administration dimension after with drawn result.

• 한국항해항만학회지
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• 제34권2호
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• pp.97-103
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• 2010

It has been recognized that the risk from the vulnerability of GPS can lead to the extreme damage in the infrastructure of the civil and military in recent years. As an example, the intentional interference to GPS signal, named GPS jamming, was really performed to misguide GPS guided weapons during Iraq war in 2003, and the fact has also followed by the serious issues on GPS in civilian community. In the modernized military society, the navigation warfare(NAVWAR) based on the GPS jamming has been emerged and introduced as a military operation. The intentional interference to the future global navigation satellite system(GNSS) involving GPS must be also an important issue to civilian users in near future. This study is focused on the fundamental research prior to the research on "Potential principle of NAVWAR" under NAVWAR of the future warfare. In this paper, we would study on the investigation of NAVWAR based on electronic warfare(EW) and analyze characteristics of the jamming against GNSS's receivers. Then the general mechanism on GNSS jamming is proposed.