• Journal of Yeungnam Medical Science
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• 제11권1호
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• pp.35-41
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• 1994

저자들은 1988년 10월부터 1994년 2월까지 최근 5년 4개월간 영남대학교 의과대학 부속병원 일반외과에 입원하여 수술로서 확진된 선천성 회장 폐쇄증 환자 8명을 대상으로 임상분석하여 다음과 같은 결론을 얻었다. 1. 총 8명중 남아 4명, 여아 4명으로 남녀비가 동일하였으며, 입원시 연령은 생후 3일내가 6례로 75%를 차지하였다. 2. 선천성 회장폐쇄의 원인으로는 Type IIIa가 3례(37.5%)로 가장 많았으며, Type I 2례, Type II 2례, Type IIIb 1례 이었으며, Tape IV는 l례도 없었다. 3. 8명의 환아중 미숙아는 1명으로 저체중아였으며, 나머지 7명은 만삭아였다. 산모의 임신중 병력상 특별한 이상은 없었으며, 형제중 발생순위는 2째 아이에서 4례로 가장 많았다. 4. 주요 임상증상으로는 복부팽만과 구토로 7례에서 나타났고, 구토는 담즙성이었다. 5. 진단은 임상증상과 단순복부 촬영상 팽만된 장관 및 air-fluid level등을 보고 응급수술을 시행하였으며, 다른 질환과의 감별을 위해 2례에서는 대장조영술도 함께 시행 하였다. 6. 8명의 환아중 7명에서 장절제후 단단 문합술을 시행하였으며, 1명에서는 고위쇄항으로 횡행 결장조루술도 함께 시행 하였다. 7. 동반된 기형은 Type IIIa 1례에서 고위쇄항, 좌측신 무발육증, 우측 다낭신 및 후복막낭종등을 동반하였다. 8. 수술후 합병증은 8례중 3례(37.5%)에서 패혈증이 발생 하였으며, 술후 사망한 경우도 이들 패혈증을 동반한 3례 이었다. 나머지 5명은 현재까지 특별한 문제없이 건강하게 잘 자라고 있다.

• Journal of Yeungnam Medical Science
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• 제11권1호
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• pp.127-134
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• 1994

1991년 5월 1일부터 1993년 7월 31일까지 영남대학교 의과대학 부속병원 산부인과에서 시행한 136례의 골반경수술에서 다음과 같은 결론을 얻었다. 환자의 나이 분포는 19세에서 55세였고 평균 나이는 31.2세였다. 평균 분만력은 0.96이었으며 거의 대부분의 환자는 2회 이하의 분만력을 보였다. 골반경수술의 가장 많은 적응증은 난관 임신이었고 그 다음으로는 난소낭종이었다. 시술 방법은 주로 난관절제술(58.8%)과 난소난관절제술(16.3%)이었고 입원기간은 평균 2.1일이었고 모든 경우에는 특별한 합병증이 없었다. 이러한 연구결과로 보아 골반경수술은 경제적으로나 사회적으로 또 미용학적으로도 좋은 결과를 보였으며 앞으로 다른 많은 부인과 환자에게 안전하게 적용할 수 있으리라 사료된다.

• Nutrition Research and Practice
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• 제14권1호
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• pp.20-24
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• 2020

BACKGROUND/OBJECTIVES: Malnutrition has multiple impacts on surgical success, postoperative complications, duration of hospital stay, and costs, particularly for cancer patients. There are various nutrition risk screening tools available for clinical use. Herein, we aim to determine the most appropriate nutritional risk screening system for esophageal cancer (EC) patients in China. SUBJECTS/METHODS: In total, 138 EC patients were enrolled in this study and evaluated by experienced nurses using three different nutritional screening tools, the Nutrition Risk Screening 2002 tool (NRS2002), the Patient-generated Subjective Globe Assessment (PG-SGA), and the Nutrition Risk Index (NRI).We compared sensitivity, specificity, positive and negative likelihood ratios, and Youden index generated by each of the three screening tools. Finally, cut-off points for all three tools were re-defined to optimize and validate the best nutritional risk screening tool for assessing EC patients. RESULTS: Our data suggested that all three screening tools were 100% sensitive for EC patients, while the specificities were 44.4%, 2.96%, and 59.26% for NRS 2002, PG-SGA, and NRI, respectively. NRI had a higher positive likelihood ratio as well as a higher area under the receiver operating characteristic curve compared to those of NRS 2002 and PG-SGA; although, all three tools had null negative likelihood ratios. After adjusting the cut-off points, the specificity and accuracy for all tools were significantly improved, however, the NRI remained the most appropriate nutritional risk screening system for EC patients. CONCLUSIONS: The NRI is the most suitable (highest sensitivity and accuracy) nutritional risk screening tool for EC patients. The performance of the NRI can be significantly improved if the cut-off point is modified according to the results obtained using MedCalc software.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제37권
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• pp.30.1-30.7
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• 2015

Background: The inferior alveolar nerve (IAN) may be injured during extraction of the mandibular third molar, causing severe postoperative complications. Many methods have been described for evaluating the relative position between the mandibular third molar and the inferior alveolar canal (IAC) on panoramic radiography and computed tomography, but conventional radiography provides limited information on the proximity of these two structures. The present study assessed the benefits of three-dimensional computed tomography (3D-CT) prior to surgical extraction of the mandibular third molar, to prevent IAN damage. Methods: This retrospective study included 4917 extractions in 3555 patients who presented for extraction of the mandibular third molars. The cases were classified into three groups, according to anatomical relationship between the mandibular third molars and the IAC on panoramic radiography and whether 3D-CT was performed. Symptoms of IAN damage were assessed using the touch-recognition test. Data were compared using the chi-square test and Fisher's exact test. Results: Among the 32 cases of IAN damage, 6 cases were included in group I (0.35 %, n = 1735 cases), 23 cases in group II (1.1 %, n = 2063 cases), and 3 cases in group III (0.27 %, n = 1119 cases). The chi-square test showed a significant difference in the incidence of IAN damage between groups I and II. No significant difference was observed between groups I and III using Fisher's exact test. In the 6 cases of IAN damage in group I, the mandibular third molar roots were located lingual relative to the IAC in 3 cases and middle relative to the IAC in 3 cases. The overlap was ${\geq}2mm$ in 3 of 6 cases and 0-2 mm in the remaining 3 cases. The mean distance between the mandibular third molar and IAC was 2.2 mm, the maximum distance 12 mm, and the minimum distance 0.5 mm. Greater than 80 % recovery was observed in 15 of 32 (46.8 %) cases of IAN damage. Conclusions: 3D-CT may be a useful tool for assessing the three-dimensional anatomical relationship and proximity between the mandibular third molar and IAC in order to prevent IAN damage during extraction of mandibular third molars.

• Clinics in Shoulder and Elbow
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• 제14권1호
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• pp.1-5
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• 2011

목적: 불안정성 쇄골 원위부 골절에서 Endobutton을 이용한 오구 쇄골 인대 보강술을 시행하고 그 방사선학적 및 임상적 결과를 알아보고자 하였다. 대상 및 방법: 2007년 10월부터 2009년 9월까지 오구 쇄골 인대 손상이 동반된 Neer 제 2형 불안정성 쇄골 원위부 골절로 TightRope$^{(R)}$ 고정술을 시행하고 1년 이상 추시 관찰이 가능하였던 연속적 9예를 대상으로 하였다. 방사선적 평가는 단순 방사선 사진을 이용하여 오구 쇄골 간격 측정 및 골유합을 판단하였고, 임상적 평가는 ASES 평가 점수를 이용하였다. 결과: 8예 (88.9%)에서 골유합을 얻을 수 있었으며, 평균 골유합 기간은 12.9 (9~16)주였다. 술 후 및 최종 추시 평균 오구 쇄골 간격은 5.6 mm, 6.2 mm로 통계학적으로 의미있는 정복의 소실은 없었다 (p>0.05). ASES 점수는 평균 90.3 (78~96)점으로 우수 6예, 양호 2예, 보통 1예였으며, 8예 (88.9%)에서 만족할 만한 결과를 나타내었다. 합병증으로 1예에서 초기 정복 소실로 인하여 불유합이 발생하였으며, 보통의 임상적 결과를 보였다. 그 외 고정물의 파손 및 감염 등의 합병증은 없었다. 결론: 불안정성 쇄골 원위부 골절에서 TightRope$^{(R)}$ 고정술은 고정물의 제거가 필요하지 않다는 장점이 있으며, 원위 골편의 고정이 어려운 골절에서 안정된 고정을 얻을 수 있는 하나의 대안이 될 수 있을 것으로 생각된다.

• Archives of Plastic Surgery
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• 제32권1호
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• pp.85-92
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• 2005

Botulinum toxin type A is widely used for anti-wrinkling therapy, and correction of the square face. The toxin ultimately prevent the release of membrane-bound acetylcholine at the neuromuscular junction of striated muscles and thus produce chemical denervation and paralysis of the muscles. Our purpose of study is to know if application of botulinum toxin type A on calf reduction is effective, how much dosage is effective, and what are the possible complications. We reviewed data of 30 consecutive patients subjected to calf reduction in Dong-A University Hospital from February 2003 to April 2003. We injected normal saline 2cc on both calves region in 15 control group patients, and the other patients was divided 3 group. Group 1, Group 2, Group 3 was injected 50U, 100U, 150U botulinum toxin A on each calf region and followed up for 6 month. Maximal circumference of calf was not changed in the control group but an average of 0.7 cm reduction was noted in group 1, average 1.34 cm(right calf) and 1.26cm(left calf) in group 2, average 1.44cm(right calf) and 1.58cm(left calf) in group 3. Maximal area of calf was not changed in the control group but average reduction of 12.5%(right calf) and 12.7%(left calf) was obtained in group 1, average 19.4% (right calf) and 19.9%(left calf) in group 2, average 24.8%(right calf) and 21.07%(left calf) in group 3, as measured on CAT scan. Total fat amount and fat amount in the lower extremity was no change in all the groups, but lean body mass was decreased average 1.27%(right calf) and 1.15%(left calf) in group 1, average 3.47%(right calf) and 2.98%(left calf) in group 2, average 3.58%(right calf) and 3.95%(left calf) in group 3. Photography of the preoperative and postoperative 6 month state revealed higher satisfaction in Group 2, 3 compared to Group 1. Use of botulinum toxin type A in calf reduction is a very simple, safe, non-invasive method and effective in terms of calf contouring rather than reduction of calf circumference.

• Journal of Chest Surgery
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• 제27권3호
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• pp.177-186
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• 1994

Pentastarch is a hydroxyethyl starch similar to hetastarch, but lower average molecular weight and fewer hydroxyethyl groups which result in enhanced enzymatic hydrolysis and faster renal elimination.This report was performed to compare the clinical efficacy and safety of 10 % pentastarch[Pentaspan , group I] for plasma volume expansion after open heart surgery with that of 5% albumin[Plasmanate, group II]. There were no statistically significant differences between the group I [n=18] and group II [n:19] in the preoperative parameters [age, sex, body weight] and operative parameters[bypass time, aorta cross clamping time]. During the first 24 hours after arrival of the patient in the surgical intensive care unit, colloid solution [500--1000 ml] was infused to maintain left atrial pressure of more than 8 mmHg, or cardiac index of 2.0 L/min/M2 of more. In results, there were 3 complications of hypotension immediately after infusion of 5 % albumin solution and 2 among the 3 patients were excluded for the study. However there was no complication after infusion of 10 % pentastarch solution. Hemodynamic responses to infusion was similar for both groups, although in group I a greater increase in both left atrial pressure[mean 1.8 versus 0.7 mmHg, p< 0.05] and right atrial pressure [mean 2.2 versus 1.7 mmHg, p < 0.05] was observed during infusion of the first 500 ml. There were no significant differences in any of the measured respiratory parameters[PaO2, intrapulmonary shunt, and effective lung compliance]. Homodilution with colloid significantly reduced hemoglobin [mean 1.2 versus 0.8 gm/dl], and serum protein and albumin level[total protein;4.8$\pm$ 0.5 versus 5.2 $\pm$0.5 gm/dl, p < 0.05: albumin: 3.2 $\pm$0.4 versus 3.6 $\pm$0.6 gm/dl, p < 0.05] by 6:00 AM on 1 day postoperatively, however there were no significant differences on 7 day postoperatively. The mean serum colloid osmotic pressure and osmolarity was similar in both group.There were no abnormal findings of liver function and kidney function in all the patients. There were no significant between-group differences in bleeding time, platelets, prothrombin time, activated partial thromboplastin time and amount of chest tube output measured on 1st and 7th postoperative day. These findings demonstrated that 10% pentastarch is more effective and safe for plasma volume expension than 5 % albumin solution with no adverse effects on coagulation. Also 10 % pentastarch is less expensive than 5 % albumin and it would appeare to be a reasonable first choice for plasma volume expansion.

• Journal of Chest Surgery
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• 제39권1호
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• pp.12-17
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• 2006

배경: 초 저체온 하 순환 정지는 총 폐정맥 환류 이상을 수술하는데 있어 중요한 보조 수단이다. 그러나 초 저체온 하 순환 정지 하에 심장 수술을 하는 것은 순환 정지 후 신경계 이상의 위험을 동반하고 있다. 이에 완전 순환 정지 없이 총 폐정맥 환류 이상을 수술하여 그 결과를 평가하고자 한다. 대상 및 방법: 2000년 4월에서 2004년 10월까지 10명의 환자의 의무 기록을 후향적으로 분석하였다. 결과: 해부학적 연결 이상의 위치는 심장 상부형이 7예,심장형이 1예, 심장 하부형이 2예였다. 평균 심폐기 가동 시간과 대동맥 차단 시간은 각각 116.8 $\pm$40.7분, 69.5$\pm$24.1분이었다. 수술로 인한 사망 예는 없었고, 합병증은 술 후 폐정맥 협착이 1예, 폐렴, 기흉, 창상 감염, 횡격막 마비가 각각 1예씩 있었다. 평균 16.6개월의 추적 관찰 기간동안 페동맥 협착이 없었던 모든 환아는 NYHA class I으로 지내고 있다. 결론: 총 폐정맥 환류 이상을 완전 순환 정지 없이 수술하여 아주 만족할 만한 결과를 얻을 수 있었다.

• Journal of Chest Surgery
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• 제30권1호
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• pp.55-60
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• 1997

본 인제대학교 의과대학 서을 백병원 흉부외과학교실에서는 1987년 9월 부터 1995년 12월까지 원발성 종격동 종양의 진단하에 수술을 시행한 40례를 대상으로 하여 임상적 고찰을 하였다. 관찰 대상은 남자 18례와 여자 22례로 연령은 Vll에서 68세까지 였으며 평균 )4.1세였다. 종양의 진단시 증상은 흉통(12.5%), 기침(12.5%), 호흡곤란(7.5%) 경부종괴(7.5%), 흉부불쾌감(5.0%) 등이었다. 진단은 모든 예에서 단순 흉부엑스선 사진과 흉부 전산화단층촬영을 실시하였고 5례 에서는 자기공명영상을 시행하였다. 경피적 침생검은 22례에서 시행하여 16례에서 조직학적 진단을 얻었다(민감도 72.7%). 종양의 위치별 분포는 전상부 종격동 24례(60.0%), 후부 종격동 14례(35.0%), 중부 종격동 2례(5.0%)였다. 종양의 종류는 흉선종 11례(27.5%), 신경성종양 10례(25.0%), 배아세포종 7례(17.5%), 낭종 8례(20.0%), 거대 림프 절비대(Castleman's disease) 2례(5.0%), 방추세포육종 1례(2.5%) 그리고 림프종 1례(2.5%), 였다. 악성 종양은 5례로 침습성 흉선종 3례, 방추세포육종 1례, 림프종 1례였다. 치료는 양성의 모든 예와 악성종양 3례에서 완전절제하였고, 2례는 수술이 불가능하였다. 수술후 사망은 없었고 합병증은 창상피열, 성대마비, 어깨강직이 각각 1례씩 있었다.

• 대한두경부종양학회지
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• 제15권1호
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• pp.35-39
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• 1999

Objectives: The treatment for squamous cell carcinoma of the tonsil remains controversial. Surgery or radiation therapy alone is effective in treating early tonsil cancer, but results with single treatment modality in advanced disease have been disappointing. We retrospectively analyzed 37 patients with advanced squamous cell carcinoma of the tonsil for two treatment modalities in an effort to identify more efficacious therapeutic options. Materials and Methods: From 1990 through 1997, 37 patients who were treated primarily with surgery, were retrospectively sudied. The patients were grouped into two groups according to the method of treatment, extended tonsillectomy followed by irradiation and/or postradiation neck dissection(Group I) and a combination of composite resection and postoperative radiation(Group II). Results: The three year disease-tree survival in patients with stage IV lesions was 59.09% for the Group I patients, and 56.25% for the Group II patients. This difference was not statistically significant(p=0.775). The primary tumor recurrence rate in Group I was 16.7% in contrast to 23.1% for Group II. The local recurrence rate in the neck was 16.7% for the Group I patients and 23.1% for the Group II patients. There was no significant difference in the frequency of recurrences in the primary or neck in the patients treated with extended tonsillectomy or composite resection(p=0.639). Fistula formation and aspiration occurred in four patients after composite resection. Additionally, there were three trismus, one soft tissue necrosis, and one velopharyngeal insufficiency. Major complications were not observed in the patients treated with extended tonsillectomy and irradiation: velopharyngeal insufficiency was observed in eight patients and soft tissue necrosis in two patients. Conclusion: Extended tonsillectomy followed by irradiation may be an effective therapy with low morbidity in selected patients with tonsil cancer.