• Journal of the Architectural Institute of Korea Planning & Design
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• v.36 no.1
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• pp.37-48
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• 2020

Logistics centers, distribution centers, or warehouse facilities increasingly dominate urban and suburban landscapes, their enormous but blank, repetitive facades completely overshadowing adjacent buildings. Mostly ignored by architects, this new building type symbolically represents the arrival of post-anthropocene, or post-urbicene era of architecture, in which an increasing portion of our built environment will not be intended for human occupancy, but rather for use by machines and artificial intelligence. As a new wave of logistics centers are becoming more automated, and more supersized, it is important to deepen architects' understanding of the organizational logic and programming factors that inform the overall design decisions for these facilities. With a particular focus on three case studies--Coupang, E-Mart, and Amazon Fulfillment Centers, this research examines the current trends in automation and expansion of logistics centers, and offers an analysis and forecast for future facilities in South Korea.

• Journal of Fashion Business
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• v.27 no.2
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• pp.52-69
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• 2023

Based on five types of health KF masks currently being commercialized, this study analyzed results of a survey of 316 male and female college students with experience in wearing health masks in Seoul metropolitan area. By identifying problems and improvement requirements according to current status of wearing health masks, results of this study could be used as basic data for designing ergonomic health mask with improved ease of wearing and satisfaction for human safety protection in the future. SPSS 26.0 statistical program was used for all data analyses, including post-hoc test, χ² test for cross-analysis, frequency analysis, independent samples t-test, ANOVA, and Duncan test. Considering that masks are worn for more than 8 hours a day on average, it is necessary to design masks considering materials, sizes of mask ear straps, elasticity and thickness of straps. The design should minimize contact with lips and cheeks with improved fit and comfort, blocking performance, and aesthetics. According to this survey, nearly 50% of respondents said they were willing to wear masks even after the end of COVID-19. Thus, it is necessary to perform research and improve masks to have excellent colors, designs, shapes, fit, and functions suitable for both pandemic and post-pandemic era when wearing masks is common.

• BMB Reports
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• v.37 no.1
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• pp.75-82
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• 2004

Recent years saw a dramatic increase in genomic and proteomic data in public archives. Now with the complete genome sequences of human and other species in hand, detailed analyses of the genome sequences will undoubtedly improve our understanding of biological systems and at the same time require sophisticated bioinformatic tools. Here we review what computational challenges are ahead and what are the new exciting developments in this exciting field.

• Korean Journal of Biological Psychiatry
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• v.15 no.4
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• pp.243-253
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• 2008

In the post-genomic era, the mechanisms controlling activation of genes are thought to be more important. Gene-environment interactions are crucial in both development and treatment of psychiatric disorders as they are complex genetic disorders. Epigenetics is defined as a change of gene expression that occurs without a change of DNA sequence and can be heritable by certain mechanisms. Epigenetic changes play essential roles in control of gene activation. DNA methylation, chromatin remodeling and RNAi act as key mechanisms for epigenetic modifications of genes. Here, we review the basic mechanisms of epigenetics and discuss their potential involvement of human diseases, including psychiatric disorders.

• Journal of Fashion Business
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• v.3 no.4
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• pp.55-66
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• 1999

The purpose of this study was to analyze the changes and characteristics of street fashion in Japan of the 1980s. The data were collected from the Mainichi Newspaper published in Japan from 1950 to 1990. The results were as follows: 1. After world war II, the street fashion had changed through the styles of the Panpan, Apres, Miyuki, Hippie & Hooten, Bikers in Japan. 2. The 1980s was characterized as an era of post industrial society and the appearance of Shinjinrui which means new human. In street fashion, these changes led to greater focus on unique style in Japan. In the 1980s, the street fashion had developed within four styles : traditional casual wear style, American sports wear style, performance.oriented style, and Japanese DC brand style in Japan.

• Molecules and Cells
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• v.22 no.2
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• pp.127-132
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• 2006

In the post genome project era, it is well established that the human genome contains a smaller number of genes than expected. The complexity found in higher organisms can be explained if proteins are multifunctional. Indeed, recent studies are continuing to reveal proteins that are capable of a broad repertoire of functions. A good paradigm for multifunctionality can be found in the amino-acyl tRNA synthetases (aaRSs), an ancient conserved family of proteins. This unique family, which is comprised of 20 different enzymes, is well known for its participation in protein synthesis. Several studies have described numerous examples of these "housekeeping" proteins taking part in extensive critical cellular activities. In this review, we focus on a member of that family, lysyl-tRNA synthetase (LysRS), which has been shown to have a dual functionality. In addition to its contribution to the translation process, LysRS also takes part in the regulation of MITF and USF2 target genes. This phenomenon was first described in mast cells.

• Electronics and Telecommunications Trends
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• v.34 no.1
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• pp.23-35
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• 2019

In the upcoming post-app era, real-time, intelligent and immersive services such as autonomous vehicles, virtual secretaries, virtual reality, and augmented reality are expected to dominate. However, there is a growing demand for new networking and computing infrastructure capabilities because existing physical connection-oriented networks and centralized cloud-based service environments have inherent limitations to effectively accommodate these services. To this end, research on intelligent edge network computing technology is underway to analyze the contextual situation of human and things and to configure the service environment on the network edge so that the application services can be performed optimally. In this article, we describe the technology issues for edge network intelligence and introduce related research trends.

• Animal cells and systems
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• v.5 no.2
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• pp.153-156
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• 2001

A key aspect of genomic research in the “post-genome era”is to associate sequence variations with heritable phenotypes. The most common variations in the human genome are single nucleotide polymorphisms (SNPs) that occur approximately once in every 500 to 1,000 bases. Although analyzing the phenotypic outcome of these SNPs is crucial to facilitate large-scale association studies of genetic diseases, detection of SNPs from an extended number of human DNA samples is often difficult, labor-intensive and time-consuming. Recent development in SNP detection methods using DNA microarrays and mass spectrophotometry has allowed automated high throughput analyses, but such equipments are not accessible to many scientists. In this study, we demonstrate that a simple PCR-based method using primers with a mismatched base at the 3'-end provides a fast and easy tool to identify known SNPs from human genomic DNA in a regular molecular biology laboratory. Results from this PCR amplification of specific alleles (PASA) analysis efficiently and accurately typed the Q576R polymorphism of human IL4 receptor from the genomic DNAs of 29 Koreans, including 9 samples whose genotype could not be discerned by the conventiona1 PCR-SSCP (single strand conformation polymorphism) method. Given the increasing attention to disease-associated polymorphisms in genomic research, this alternative technique will be very useful to identify SNPs in large-scale population studies.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.15 no.2
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• pp.41-56
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• 2012

Landscape space can and should play as a multi-functional agent : healing contaminated soil, reducing natural hazards, supporting living things, making comfortable environment for human, and appealing to human aesthetics, etc. This article aims to show the possibility and role of landscape space as such agent. In landscape design for National Marine Biology Resource Institute, distributed rain water treatment system and rain gardens are introduced to replace a mono-functioning large detention pond which was suggested by disaster impact assesment. Phytoremediation and vegetation filtering system with muti-cell wetlands are also adapted to heal the contaminated soil. This kind of landscape as a 'living machine' which can play as an operational control utility of multi-environment and thus can be combined effectively into green infrastructure is important for post-industrial city, especially in an era of climate change.

• Proceedings of the IEEK Conference
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• 2002.07c
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• pp.1788-1791
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• 2002

In the post-genome era. it is one of important research subject to Investigate the roles of the proteins in human body based on decoded genome information during Human Genome Project. In order to clarify them. it is necessary to analyze the structure of the protein crystals and their function. ' Crystallization is the beginning stage of protein structure determination process. There are some methods for structural analysis of the proteins, and general one is X-ray structural analysis method. In order to utilize this method for analyzing the protein crystal's structure, artificial protein crystallization is required. However, since artificial crystallizing work takes much time and manpower. the performance against its cost is still low. Therefore. we started to discuss to develop a supporting system for improving efficiency of the crystallization distinction procedure. In this paper, we examine to realize such supporting system for crystallization distinction using image-processing technique and report about our experimental result with many real protein solution images.