• Title/Summary/Keyword: Post-classification

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Inflammation and Oxidative Stress as related to Airflow Limitation Severity in Retired Miners with Chronic Obstructive Pulmonary Disease (광산 이직근로자의 만성폐쇄성폐질환 기류제한 중증도와 염증 및 산화스트레스)

  • Lee, Jong Seong;Shin, Jae Hoon;Baek, Jin Ee;Jeong, Ji Yeong;Choi, Byung-Soon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.29 no.2
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    • pp.251-258
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    • 2019
  • Objective: Chronic obstructive pulmonary disease(COPD) is characterized by persistent airflow limitations associated with chronic inflammatory response due to noxious particles or gases in the lung. Inflammation and oxidative stress are associated with COPD. The aim of this study was to evaluate the relationship among inflammation, oxidative stress, and airflow limitation severity in retired miners with COPD. Methods: The levels of serum high-sensitivity C-reactive protein(hsCRP) as a biomarker for inflammation, degree of reactive oxygen metabolites(dROMs) and biological antioxidants potential(BAP) in plasma as biomarkers for oxidative stress were measured in 211 male subjects with COPD. Degree of airflow limitation severity as determined by spirometry was divided into three grades grouped according to the classification of the Global Initiatives for Obstructive Lung Disease(GOLD)(1, mild; 2, moderate; $3{\leq}$, severe or more) using a fixed ratio, post- bronchodilator $FEV_1/FVC$ < 0.7. Results: Mean levels of dROMs significantly increased in relation to airflow limitation severity(GOLD 1, 317.8 U.CARR vs. GOLD 2, 320.3 U.CARR vs. GOLD $3{\leq}$, 350.9 U.CARR, p=0.047) and dROMs levels were correlated with serum hsCRP levels(r=0.514, p<0.001). Mean levels of hsCRP were higher in current smokers(non-smoker, 1.47 mg/L vs. smoker, 2.34 mg/L, p=0.006), and tended to increase with degree of airflow limitation severity(p=0.071). Mean levels of BAP were lower in current smokers(non-smoker, $1873{\mu}mol/L$ vs. smoker, $1754{\mu}mol/L$, p=0.006). Conclusions: These results suggest that inflammation and oxidative stress are related to airflow limitation severity in retired miners with COPD, and there was a correlation between inflammation and oxidative stress.

Oncological and functional outcomes following robot-assisted laparoscopic radical prostatectomy at a single institution: a minimum 5-year follow-up

  • Kang, Jun-Koo;Chung, Jae-Wook;Chun, So Young;Ha, Yun-Sok;Choi, Seock Hwan;Lee, Jun Nyung;Kim, Bum Soo;Yoon, Ghil Suk;Kim, Hyun Tae;Kim, Tae-Hwan;Kwon, Tae Gyun
    • Journal of Yeungnam Medical Science
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    • v.35 no.2
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    • pp.171-178
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    • 2018
  • Background: To evaluate mid-term oncological and functional outcomes in patients with prostate cancer treated by robot-assisted laparoscopic radical prostatectomy (RALP) at our institution. Methods: We retrospectively reviewed the medical records of 128 patients with prostate cancer who underwent RALP at our institution between February 2008 and April 2010. All patients enrolled in this study were followed up for at least 5 years. We analyzed biochemical recurrence (BCR)-free survival using a Kaplan-Meier survival curve analysis and predictive factors for BCR using multivariate Cox regression analysis. Continence recovery rate, defined as no use of urinary pads, was also evaluated. Results: Based on the D'Amico risk classification, there were 30 low-risk patients (23.4%), 47 intermediaterisk patients (38.8%), and 51 high-risk patients (39.8%), preoperatively. Based on pathological findings, 50.0% of patients (64/128) showed non-organ confined disease (${\geq}T3a$) and 26.6% (34/128) had high grade disease (Gleason score ${\geq}8$). During a median follow-up period of 71 months (range, 66-78 months), the frequency of BCR was 33.6% (43/128) and the median BCR-free survival was 65.9 (0.4-88.0) months. Multivariate Cox regression analysis revealed that high grade disease (Gleason score ${\geq}8$) was an independent predictor for BCR (hazard ratio=4.180, 95% confidence interval=1.02-17.12, p=0.047). In addition, a majority of patients remained continent following the RALP procedure, without the need for additional intervention for post-prostatectomy incontinence. Conclusion: Our study demonstrated acceptable outcomes following an initial RALP procedure, despite 50% of the patients investigated demonstrating high-risk features associated with non-organ confined disease.

An Analysis of Dwelling Environment of Public Retirement(Silver) Housing Based on Post Occupancy Evaluation (거주 후 평가(P.O.E)에 의한 공공실버주택의 거주환경 분석)

  • Bak, Da-Hye;Kim, Young-Hwa;Lee, Sang-Hong
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.12
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    • pp.65-76
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    • 2018
  • Due to the rapid demographic and structural changes, Korea has faced a variety of social issues and quickly entered the aged society since the 2000s. In order deal with this reality, diverse types of welfare policies are emerging in the society as a whole. The government began to supply domestic public silver housing in 2016 to provide against the quickly growing aged society and now, the government is planning to supply approximately 50,000 housing by 2022 for quantitative growth of aged society, by selecting 1st and 2nd designated areas for the project additionally. This public retirement(silver) housing combines 'space' with 'service'. The lower floors are a public silver welfare Facilities and the upper floors are a housing spaces. This type of housing is to deal with requirements of rental housing residents by combining physical space with supporting service. Based on barrier-free design, the complex and unit house have safety handles and alarm bells in the bathroom, undulating washstands, bathroom sliding doors, corridor safety handles, and emergency safety exit lamps in each housing unit so the aged and the disabled can use easily and conveniently. Also, hand rails are installed and stepped pulleys are removed to promote convenience. Currently, the government is planning to increase the supply, focusing on low-income groups, such as beneficiaries of national basic livelihood and the working poor. Recognizing that the public retirement(silver) housing project is at its early stage, this study examined satisfaction, based on evaluations of real residents. This study aimed to obtain more empirical research data and apply them to public retirement(silver) house space analysis. For analysis, this study targeted Wirye public retirement(silver) housing and Magnolia public retirement(silver) housing that are in operation, and literature review, previous research review, and field survey were conducted to examine the present state. Using the questionnaires consisting of four large classification items; Block Layout, Housing Unit, Welfare Facilities, and Barrier-free Design, and sub-details, a survey was conducted to analyze residents' satisfaction. In conclusion, it is anticipated that this study would serve as basic research data about public retirement(silver) housing to increase continuously in future by analyzing public retirement(silver) housing spaces, on the basis of the analyzed data.

Methodological Status and Improvement of Additional Evaluation of Health Impact Items in Environmental Impact Assessment (환경영향평가서 내 건강영향 항목 추가·평가의 방법론적 현황과 개선)

  • Ha, Jongsik
    • Journal of Environmental Impact Assessment
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    • v.29 no.6
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    • pp.453-466
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    • 2020
  • The addition and evaluation of health impact items in Environmental Impact Assessment document are written in hygiene and public health items only for specific development projects and are being reviewed. However, after the publication of the evaluation manual on the addition and evaluation of health impact items in 2011, there is a demand for continuous methodology and improvement plans despite partial improvement. Therefore, in order to propose a methodological improvement of the evaluation manual, this technical paper identified detailed improvement requirements based on the consultation opinions on hygiene and public health items, and investigated and suggested ways to solve this problem by reviewing the contents of the research so far. As for the improvement requirements, the contents related to mitigation plan, post management, effect prediction, assessment, and present-condition investigation were presented in Environmental Impact Assessment documents for the entire development project at a frequency of 93%, 85%, 80%, 74%, and 67%, respectively. Particularly, the detailed improvement requirements related to mitigation plan consisted of an establishment direction and a management of development project. Considering the current evaluation manual and the frequency of improvement requirements, this paper proposed concrete methods or improvement plans for major methodologies for each classification of hygiene and public health items. Furthermore, a comprehensive evaluation methodology related to whether a project is implemented was proposed, which is not provided in the current assessment manual.

Human Skeleton Keypoints based Fall Detection using GRU (PoseNet과 GRU를 이용한 Skeleton Keypoints 기반 낙상 감지)

  • Kang, Yoon Kyu;Kang, Hee Yong;Weon, Dal Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.127-133
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    • 2021
  • A recent study of people physically falling focused on analyzing the motions of the falls using a recurrent neural network (RNN) and a deep learning approach to get good results from detecting 2D human poses from a single color image. In this paper, we investigate a detection method for estimating the position of the head and shoulder keypoints and the acceleration of positional change using the skeletal keypoints information extracted using PoseNet from an image obtained with a low-cost 2D RGB camera, increasing the accuracy of judgments about the falls. In particular, we propose a fall detection method based on the characteristics of post-fall posture in the fall motion-analysis method. A public data set was used to extract human skeletal features, and as a result of an experiment to find a feature extraction method that can achieve high classification accuracy, the proposed method showed a 99.8% success rate in detecting falls more effectively than a conventional, primitive skeletal data-use method.

Comparison of Long-Term Angiographic Results of Wide-Necked Intracranial Aneurysms : Endovascular Treatment with Single-Microcatheter Coiling, Double-Microcatheter Coiling, and Stent-Assisted Coiling

  • Kim, Hyun Sik;Cho, Byung Moon;Yoo, Chan Jong;Choi, Dae Han;Hyun, Dong Keun;Shim, Yu Shik;Song, Joon Ho;Oh, Jae Keun;Ahn, Jun Hyong;Kim, Ji Hee;Chang, In Bok
    • Journal of Korean Neurosurgical Society
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    • v.64 no.5
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    • pp.751-762
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    • 2021
  • Objective : Endovascular treatment of intracranial aneurysms is challenging in case of wide-necked aneurysms because coils are prone to herniate into the parent artery, causing thromboembolic events or vessel occlusion. This study aims to compare long-term angiographic results of wide-necked aneurysms treated by stent-assisted, double-microcatheter, or single-microcatheter groups. Methods : Between January 2003 and October 2016, 108 aneurysms that were treated with endovascular coil embolization with a neck size wider than 4 mm and a follow-up period of more than 3 years were selected. We performed coil embolization with single-microcatheter, double-microcatheter, and stent-assisted techniques. Angiographic results were evaluated using the Raymond-Roy occlusion classification (RROC). All medical and angiographic records were reviewed retrospectively. Results : Clinical and angiographic analyses were conducted in 108 wide-necked aneurysms. The immediate post-procedural results revealed RROC class I (complete occlusion) in 66 cases (61.1%), class II (residual neck) in 36 cases (33.3%), and class III (residual sac) in six cases (5.6%). The final follow-up results revealed class I in 48 cases (44.4%), class II in 49 cases (45.4%), and class III in 11 cases (10.2%). Of a total of 45 (41.6%) radiologic recurrences, there were 21 cases (19.4%) of major recurrence that required additional treatment, and 24 cases (22.2%) of minor recurrence. The final follow-up angiographic results showed statistically significant differences between the stent-assisted group and the others (p<0.01). Conclusion : Long-term follow-up angiography demonstrated that the stent-assisted technique had a better complete occlusion rate than the other two techniques.

Domain Knowledge Incorporated Counterfactual Example-Based Explanation for Bankruptcy Prediction Model (부도예측모형에서 도메인 지식을 통합한 반사실적 예시 기반 설명력 증진 방법)

  • Cho, Soo Hyun;Shin, Kyung-shik
    • Journal of Intelligence and Information Systems
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    • v.28 no.2
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    • pp.307-332
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    • 2022
  • One of the most intensively conducted research areas in business application study is a bankruptcy prediction model, a representative classification problem related to loan lending, investment decision making, and profitability to financial institutions. Many research demonstrated outstanding performance for bankruptcy prediction models using artificial intelligence techniques. However, since most machine learning algorithms are "black-box," AI has been identified as a prominent research topic for providing users with an explanation. Although there are many different approaches for explanations, this study focuses on explaining a bankruptcy prediction model using a counterfactual example. Users can obtain desired output from the model by using a counterfactual-based explanation, which provides an alternative case. This study introduces a counterfactual generation technique based on a genetic algorithm (GA) that leverages both domain knowledge (i.e., causal feasibility) and feature importance from a black-box model along with other critical counterfactual variables, including proximity, distribution, and sparsity. The proposed method was evaluated quantitatively and qualitatively to measure the quality and the validity.

Exploring Learning Effects of Elementary Students in a Geological Field Trip Activity concerning 'Minerals and Rocks' - Focus on Novelty Space - ('광물과 암석' 관련 야외지질학습에서 초등학생들의 학습 효과에 대한 탐색 - 생소한 경험 공간을 중심으로 -)

  • Choi, Yoon-Sung;Kim, Jong-Uk
    • Journal of the Korean earth science society
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    • v.43 no.3
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    • pp.430-445
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    • 2022
  • The purpose of this study was to explore the learning effects in elementary school students who participated in a geological field trip conducted under the theme 'minerals and rocks', focusing on novelty space. A total of 10 sixth-grade students participated in this program held at a public elementary school in Seoul as part of after-school club activities. Students observed mineral and rock samples in a classroom and outdoor learning environment. The authors collected activity papers (texts, drawing), researchers' participation notes, video and audio recordings containing the study participants' activities, and post-interview data To analyze the learning effects in the cognitive domain of students, the observation analysis framework for rock classification of Remmen and Frøyland (2020) and the rock description analysis framework of Oh (2020) were used. Additionally, to explore the learning effects of psychological and geographic areas, students' drawings, texts, discourses, and interview data were inductively analyzed. The results showed that the students demonstrated 'everyday' and 'transitional' observations in the classroom learning environment, while in the outdoor learning environment (school playground, community-based activities), they demonstrated 'transitional' and 'scientific' observations. Moreover, as the scientific observation stage progressed, more types of descriptive words for rocks were used. In terms of psychological and geographic aspects, students showed their selection of places to explore familiar outdoor learning environments, positive perceptions of outdoor learning, and aesthetic appreciation. Finally, this study not only discussed novelty space as a tool for analyzing students' learning effects but also suggested the need for an academic approach considering new learning environments, such as learning through virtual field trips.

Quantitative Evaluations of Deep Learning Models for Rapid Building Damage Detection in Disaster Areas (재난지역에서의 신속한 건물 피해 정도 감지를 위한 딥러닝 모델의 정량 평가)

  • Ser, Junho;Yang, Byungyun
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.40 no.5
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    • pp.381-391
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    • 2022
  • This paper is intended to find one of the prevailing deep learning models that are a type of AI (Artificial Intelligence) that helps rapidly detect damaged buildings where disasters occur. The models selected are SSD-512, RetinaNet, and YOLOv3 which are widely used in object detection in recent years. These models are based on one-stage detector networks that are suitable for rapid object detection. These are often used for object detection due to their advantages in structure and high speed but not for damaged building detection in disaster management. In this study, we first trained each of the algorithms on xBD dataset that provides the post-disaster imagery with damage classification labels. Next, the three models are quantitatively evaluated with the mAP(mean Average Precision) and the FPS (Frames Per Second). The mAP of YOLOv3 is recorded at 34.39%, and the FPS reached 46. The mAP of RetinaNet recorded 36.06%, which is 1.67% higher than YOLOv3, but the FPS is one-third of YOLOv3. SSD-512 received significantly lower values than the results of YOLOv3 on two quantitative indicators. In a disaster situation, a rapid and precise investigation of damaged buildings is essential for effective disaster response. Accordingly, it is expected that the results obtained through this study can be effectively used for the rapid response in disaster management.

A Study of Manufacturing Techniques based on Classification by Uses of Excavated Iron Objects from the Remains in Geumcheok-ri, Gyeongju (경주 금척리 유적 출토 철기의 용도별 분류에 따른 제작기법 고찰)

  • You, Ha Rim;Cho, Nam Chul;Shin, Yong Bi
    • Journal of Conservation Science
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    • v.38 no.3
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    • pp.217-233
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    • 2022
  • The remains found in Geumcheok-ri, Gyeongju are located in close proximity to the Ancient Tombs in Geumcheok-ri, Gyeongju (Historic Site) which were built between the late 5th and early 6th centuries, and these tombs are known to belong to the powerful rulers of that area. Using metallurgical techniques, this study was conducted on the iron objects obtained from the excavated remains in Geumcheok-ri, Gyeongju which are presumed to have a close relation to the nearby ruins that played an important role in the growth of Silla. To identify differences in manufacturing techniques based on the purpose of the iron objects, eight objects were selected after classifying them by use and the microstructure and non-metallic inclusions were investigated. The analyses results confirmed that the manufacturing process involved forging iron with a high or low carbon content to produce a particular shape, and that the carburization process was applied to iron post forging a shape to increase its strength when necessary. The mechanical properties were improved by selectively applying the steelmaking method and the heat treatment technique considering the functions of the parts, and the low temperature reduction was applied to the smelting process. Furthermore, in comparison with the iron objects excavated from the remains located in the center of Gyeongju and its outskirts, it is confirmed that there is similarity in the smelting and manufacturing techniques between these objects.