• 한국과학교육학회지
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• 제15권1호
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• pp.39-53
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• 1995

The purpose of this study was development of 'Environmental Science' of high school appropriate to Sixth Natinal Education Curriculum. In view that ultimate aim of environmental education is forming responsible environmental behaviors and the goals of values and behaviors are as important as knowledges and skills, A new environmental text of high school level was developed and it was based on analysis of seven texts and environmental education in Fifth Korean Curriculum. This text have seven units, 1.Habitates : What're the Meanings?, 2.Nuclear Energy: Can't be Avoid?, 3.Acid Rain : What're the Messages", 4.Ethanol : Is this Future Fuel?, 5.Wastes : A New War!, 6.What're the National and Global Environmental Issues? and 7.Our Water: Can Drink, Really? This text was stressed equally in goals of four environmental education and avoided from the array of knowledges. Therefore included various teaching strategies and independent actions of students. 'Open-ended value learning' and 'free behavior learning' in text were special learning parts for aquisition of values and formation of behaviors. To verify the effects of new developed environmental text, the direct learning was carried out by 286 students in total. Post test scores of experimental groups per each units were significantly higher than those of control groups about four goals, respectively. The Results of questionnaires by 50 teachers from five different schools were as follows. For validity of selecting contents for units, 74% of respondents replied positively. For classification and presentation of four goal-groups, 90% replied positively in validity and 82%, in utility. For validity of various teaching strategies, 88% and for the degree of including student-centered independent actions, 86% replied positively. For importances and expected effects of 'open-ended value learning' and 'free behavior learning', showed positive responses respectively, 88%, 92%. Therefore this text is effective to acheive four goals of environmental education equally.

• 한국건축시공학회지
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• 제11권2호
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• pp.108-115
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• 2011

본 연구는 건설사업관리 시장의 공정한 경쟁을 위하여 국내 CM 시장현황, 2010년 CM 공시업체현황 및 평가기준 분석을 통하여 CM 선정방식을 고찰하였다. 또한 건설사업관리의 평가기준의 적정성을 고찰하기 위하여 2009년도 CM 상위업체 현황과 2002년부터 2010년까지 120개 CM 용역의 참가자수와 평균 투찰율을 분석하고, 2010년 평가 결과를 공개한 6개 CM용역을 분석하였다. 이러한 고찰결과 현행 CM용역의 평가기준이 용역금액으로 결정되고 기술제안서 평가에 따른 기술력과 가격이 연계되지 못하는 등 CM 산업의 발전과 CM회사의 기술발전을 저해하는 결과들이 도출되었으므로 사업특성과 기술력 요구조건에 따른 CM자 선정방식의 개선을 제시하였다. 따라서 향후에는 사업특성별로 기술력 요구조건을 구분하는 방식과 CM 사후평가를 위한 추가의 연구 노력이 필요할 것으로 판단한다.

• 대한족부족관절학회지
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• 제3권1호
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• pp.40-48
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• 1999

The neck of the talus is its most vulnerable and fragile segment, because of narrow diameter, devoid of hyaline padding and honeycombed internally by vascular channels etc. Talar neck fractures comprise 50% of all major to the talus. The majority occurs as a result of high-energy injuries, such as motor vehicle accidents or fall from a height. Anatomically, talar surface is covered mainly with articular cartilage and blood supply to the talus is very poor. So, complications, such as non-union, avascular necrosis and post traumatic arthritis, are frequent. The authors reviewed fourteen cases of talar neck fractures treated in our clinics from Jan. 1992 to Mar. 1997, and average follow-up period was over 15 months. The results obtained were as follows; 1. Patients' average age was 31.2 years. 2. The most common cause was traffic accident(9/14, 64%), and hyperdorsiflexion injury of the ankle was common mechanism of the fractures. 3. According to the modified Hawkins classification, type I was four cases, type II was nine cases, type III was one case and type IV was no case. 4. Hawkins sign of subcortical radiolucency was found in 64% (9/14) of the fractures. 5. Avascular necrosis was occurred in 21% (3/14) of the fractures(in two cases of type II fractures, and in one of type III). 6. According to the Hawkins criteria, four cases in type I, five in type II were an excellent result. Two cases, one in type II and one in type III were good result, and two in type II were fair. One in type II was poor result.

• Toxicological Research
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• 제26권1호
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• pp.9-14
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• 2010

The evaluation of eye and skin irritation potential is essential to ensuring the safety of human in contact with a wide variety of substances. Despite this importance of irritation test, little is known with respect to the irritation potency of lomefloxacin, a fluoroquinolone antibiotic, which has been known to cause phototoxicity with an abnormal reaction of the skin. Thus, to investigate the tendency of lomefloxacin to cause eye and skin irritation, we carried out in vitro eye irritation test using Balb/c 3T3, and in vitro skin irritation test using $KeraSkin^{TM}$ human skin model system. 3T3 neutral red uptake assay has been proposed as a potential replacement alternative for the Draize Eye irritation test. In this study, the $IC_{50}$ value obtained for lomefloxacin was 375 ${\mu}g$. According to the classification model used for determining in vitro categories, lomefloxacin was classified as moderately irritant. For evaluation of skin irritation, engineered epidermal equivalents ($KeraSkin^{TM}$) were subjected to 10 and 25 mg of lomefloxacin for 15 minutes. Tissue damage was assessed by tissue viability evaluation, and by the release of a pro-inflammatory mediator, interleukin- 1${\alpha}$. Lomefloxacin increased the interleukin-1${\alpha}$ release after 15 minutes of exposure and 42 hours of post incubation, although no decrease in viability was observed. Therefore, lomefloxacin is considered to be moderately irritant to skin and eye.

• Toxicological Research
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• 제32권4호
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• pp.311-316
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• 2016

Effects of nanoparticles (NPs) on skin corrosion and irritation using three-dimensional human skin models were investigated based on the test guidelines of Organization for Economic Co-operation and Development (OECD TG431 and TG439). EpiDerm$^{TM}$ skin was incubated with NPs including those harboring iron (FeNPs), aluminum oxide (AlNPs), titanium oxide (TNPs), and silver (AgNPs) for a defined time according to the test guidelines. Cell viabilities of EpiDerm$^{TM}$ skins were measured by the 3-(4, 5-dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide based method. FeNPs, AlNPs, TNPs, and AgNPs were non-corrosive because the viability was more than 50% after 3 min exposure and more than 15% after 60 min exposure, which are the non-corrosive criteria. All NPs were also non-irritants, based on viability exceeding 50% after 60 min exposure and 42 hr post-incubation. Release of interleukin 1-alpha and histopathological analysis supported the cell viability results. These findings suggest that FeNPs, AlNPs, TNPs, and AgNPs are 'non-corrosive' and 'non-irritant' to human skin by a globally harmonized classification system.

• 대한핵의학회지
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• 제10권1호
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• pp.47-54
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• 1976

A clinical study was made on 263 patients of hypothyroidism among the 5,970 patients of various thyroid diseases diagnosed and treated at the Radioisotope Clinic and Laboratory, Seoul National University Hospital from May, 1960 to Aug., 1975. The results obtained with this study are as follows: 1) The etiological classification of hypothyroidism revealed 244 cases (93%) of primary hypothyroidism and 19 cases (7%) of secondary hypothyroidism. 2) The most frequent cause of the thyroprivic primary hypothyroidism was post radioiodine therapy with 109 cases (41.4%). 3) There were 37 cases (14%) of male and 226 cases (86%) of female, showing a ratio of 1:6. 4) The majority of patients were between the ages of 30 and 60 with the peak incidence (87 cases, 33%) in their fourth decades of lives. 5) The major symtoms and signs were weakness (97%), edema of face and extremities (92%); Decreased Achilles tendon reflex (87%), cold intolerance (82%), gain in weight (76%), constipation (58%) and cold skin (51%). 6) The cumulative incidence of hypothyroidism in patient treated with $^{131}I(3{\sim}8mci)$ was 7.2% at first year, 33.3% at tenth year and the 50% at fourteenth year and the annual increment was 2.9%. 7) The incidence of hypothyroidism related to thenumbers of $^{131}I$ the rapy was not linear. 8) The diagnostic compatibilities of the various tests to hypothyroidism were TSH (100%), $T_4$ (93.8%), 24-hour-RNIU (91.5%), ATR (86.7%), $T_3RU$ (66.1%) and BMR (64.9%).

• International Journal of Knowledge Content Development & Technology
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• 제9권4호
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• pp.7-29
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• 2019

The study was carried out to investigate the influence of demographics and social media use on perceived academic stress of secondary school students in St. Thomas Aquinas College, Akure, Nigeria. This was achieved using five research questions and four null hypotheses. The population of the study consisted of 1,107 students at ISCED level 3, out of which 286 were selected based on the Israel (2003) model for determining sample size. The Ex-Post Facto (EPT) research design of the correlational type was employed to investigate the study while questionnaire was used for data elicitation. Out of the 286 copies distributed, 192 (67% response rate) were retrieved and analyzed using descriptive statistics (frequency, percentage, mean and standard deviation) and inferential statistics (correlation and multiple regression). The findings revealed that there is high frequency of social media use among secondary school students, majorly for meeting new friends and chatting. The perceived academic stress (PAS) of the students was found to be moderate. Of the three demographics considered, only class had significant influence on PAS. Use of social media did not have significantly influence on PAS of the students. When combined, demographics and social media use predicted PAS; and when considered relatively, of the independent variables, only class as an aspect of demographics predicted PAS. Therefore, the authors concluded that PAS of secondary school students is not directly influenced by demographics (except for class) and social media use. Based on the study's conclusion, recommendations were made.

• 아동학회지
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• 제23권1호
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• pp.153-171
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• 2002

영아기의 애착형성이 어머니의 특성에 따른 상호작용에 의해 안정애착 혹은 불안정 애착으로 발달된다는 이론이 널리 알려지면서 불안정 애착에 대한 예방과 치료중재의 필요성이 고취되어졌음에도 불구하고, 가장 결정적인 문제인 어머니의 어떤 특성들이 아동의 불안정애착 형성에 직접적인 영향을 미치는가에 대한 연구는 거의 전무한 실정이다. 이에 따라 본 연구는 어머니와 아동간의 세대간 애착순환을 재검증함과 동시에 어머니의 양육스트레스가 어머니-아동 불안정 애착전이를 예방 및 중재시킬 수 있는 매개변인이 되는지를 검증하고자 한다. 영아기 이후의 애착형성에 대한 이해를 확장시키기 위한 시도에서, 30개월에 달한 아동과 어머니 53쌍이 조사 관찰되어졌고, 이는 아동발달의 관점에서 이 아동들이 49개월에 달했을 때 다시 조사 관찰되어졌다. 아동양육과 관련된 어머니 특성들을 측정하기 위하여 the Attachment Style Questionnaire와 the Parental Stress Inventory를 사용하였고, 아동애착안정성을 측정하기 위하여 the Separation-Reunion Classifications (1차)와 the Attachment Q-set (2차)이 사용되어졌으며, 이를 분석하기 위해 Amos structural equation 통계분석법이 사용되었다. 이에 따른 본 연구결과는, 아동애착안정성은 어머니 애착유형과 유의미하게 관련되어 있다는 것을 증명하였고, 단 이러한 관계는 어머니 스트레스 형태를 통하여 전달 형성된다는 것을 입증하였다. 더욱이 본 연구는 어머니-아동 애착 형성의 순환에 있어서 직접적인 경로가 없다는 것을 밝혀 줌으로서, 세대간 불안정애착 유형 순환 붕괴의 가능성을 제시하였다.

• 대한두개안면성형외과학회지
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• 제18권2호
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• pp.92-96
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• 2017

Background: All nasal bone fractures have the potential for worsening of olfactory function. However, few studies have studied the olfactory outcomes following reduction of nasal bone fractures. This study evaluates posttraumatic olfactory dysfunction in patients with nasal bone fracture before and after closed reduction. Methods: A prospective study was conducted for all patients presenting with nasal bone fracture (n=97). Each patient consenting to the study underwent the Korean version of Sniffin' Sticks test (KVSS II) before operation and at 6 month after closed reduction. The nasal fractures were divided according to the nasal bone fracture classification by Haug and Prather (Types I-IV). The olfactory scores were compared across fracture types and between preoperative and postoperative settings. Results: Olfactory dysfunction was frequent after nasal fracture (45/97, 46.4%). Our olfactory assessment using the KVSS II test revealed that fracture reduction was not associated with improvements in the mean test score in Type I or Type II fractures. More specifically, the mean posttraumatic Threshold, discrimination and identification score decreased from 28.8 points prior to operation to 23.1 point at 6 months for Type II fracture with septal fracture. Conclusion: Our study has revealed two alarming trends regarding post-nasal fracture olfactory dysfunction. First, our study demonstrated that almost half (46.4%) of nasal fracture patients experience posttraumatic olfactory dysfunction. Second, closed reduction of these fractures does not lead to improvements olfaction at 6 months, which suggest that olfactory dysfunction is probably due to factors other than the fracture itself. The association should be further explored between injuries that lead to nasal fracture and the mechanism behind posttraumatic olfactory dysfunction.

• 복식
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• 제62권4호
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• pp.1-14
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• 2012

Ever since the year 2000, Korea's musical markets has invited famous overseas license performances and have therefore cooperated with staffs working overseas in regards to stage costumes. This study aims to suggest the methodology of the stage costume making process according to the present advanced production system of Korea's musical market. The researcher participated in the stage costume making work of 'Chicago' as a costume supervisor. It took place at the Opera House of Seongnam Art Center from January 10, 2010 to February 28, 2010. Furthermore, there was significance in reinforcing academic values and implementing practical making process of stage-costumes based on the actual field work. The method of this research was carried out through a theoretical research and a case study that focused on empirical research. As for the research scope, it was limited to the actual stage-costumes that the researcher fully engaged with as a costume supervisor of the musical 'Chicago.' The results of this study were as follows. The stage costume making process of the musical 'Chicago' was categorized according to the classification of production system in the performance. For pre-production, it was divided according to the information of the actor and the analysis of the bible. Rehearsal period was divided according to the product clothes and fitting. Production week & preview were divided according to the changeover of clothes and the arrangement of dressers. The Run was divided according to the inspection of the situation concerning clothes in general during the performance. Post-Production Period was divided according to the collection of clothes and the implemented database. This study eventually suggested appropriate stage-costume making processes for the costumes making environment according to the expansion of overseas license musical market. However, it has a limitation of the research scope to the musical 'Chicago.' The creative performances of the domestic version are planned in diverse forms and come to abroad animate by the Korean Wave. Therefore, the field of stage-costume is necessary for the establishment of practical schemes of the system and copyright in accordance with the environment.