• Title/Summary/Keyword: Post-Failure Analysis

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Evaluation and Prediction of Post-Hepatectomy Liver Failure Using Imaging Techniques: Value of Gadoxetic Acid-Enhanced Magnetic Resonance Imaging

  • Keitaro Sofue;Ryuji Shimada;Eisuke Ueshima;Shohei Komatsu;Takeru Yamaguchi;Shinji Yabe;Yoshiko Ueno;Masatoshi Hori;Takamichi Murakami
    • Korean Journal of Radiology
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    • v.25 no.1
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    • pp.24-32
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    • 2024
  • Despite improvements in operative techniques and perioperative care, post-hepatectomy liver failure (PHLF) remains the most serious cause of morbidity and mortality after surgery, and several risk factors have been identified to predict PHLF. Although volumetric assessment using imaging contributes to surgical simulation by estimating the function of future liver remnants in predicting PHLF, liver function is assumed to be homogeneous throughout the liver. The combination of volumetric and functional analyses may be more useful for an accurate evaluation of liver function and prediction of PHLF than only volumetric analysis. Gadoxetic acid is a hepatocyte-specific magnetic resonance (MR) contrast agent that is taken up by hepatocytes via the OATP1 transporter after intravenous administration. Gadoxetic acid-enhanced MR imaging (MRI) offers information regarding both global and regional functions, leading to a more precise evaluation even in cases with heterogeneous liver function. Various indices, including signal intensity-based methods and MR relaxometry, have been proposed for the estimation of liver function and prediction of PHLF using gadoxetic acid-enhanced MRI. Recent developments in MR techniques, including high-resolution hepatobiliary phase images using deep learning image reconstruction and whole-liver T1 map acquisition, have enabled a more detailed and accurate estimation of liver function in gadoxetic acid-enhanced MRI.

Failure Mechanism Evaluation in Normally Consolidated Cohesive Soils by Plane Strain Test with Digital Image Analysis (평면변형률 시험에서 디지털 이미지 해석을 통한 정규압밀 점성토의 파괴거동 분석)

  • Kwak, Tae-Young;Kim, Joon-Young;Chung, Choong-Ki
    • Journal of the Korean Geotechnical Society
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    • v.32 no.3
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    • pp.49-60
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    • 2016
  • Soil failure is initiated and preceded by forming and progressing of shear band, defined as the localization of deformation into thin zones of soil mass. To understand the failure mechanism of normally consolidated cohesive soil, the spatial distribution and evolution of deformation within the entire specimen need to be evaluated. In this study, vertical compression tests under plane strain condition were performed on reconstituted kaolinite specimens, while capturing digital images of the specimen at regular intervals during shearing. Overall stress-strain behavior from initial to post peak has been analyzed together with spatial distributions of deformations and shear band characteristics from digital images at 4 stages.

Strut-Tie Model Analysis of PSC Simple Anchorage Zone (PSC부재 단순 정착부의 스트럿-타이 모델 해석)

  • Son, Woo-Hyun;Yun, Young-Mook
    • Proceedings of the Korea Concrete Institute Conference
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    • 2006.11a
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    • pp.269-272
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    • 2006
  • The anchorage zone of prestressed concrete members is a critical region where a large concentrated force due to prestressing by tendons is introduced. In this study, the ACI, AASHTO LRFD, CEB-FIP design criteria and the nonlinear strut-tie model approach are applied to the ultimate strength analysis of simple anchorage zones of 18 post-tensioned concrete members tested to failure. From the result of ultimate strength analysis, the advantages and disadvantages of each method are compared and discussed.

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Analysis of Effects of Chemotherapy using Failure Mode and Effect Analysis (FMEA) on Patient Safety and Safe Nursing (고장유형영향분석을 활용한 항암화학요법의 환자안전간호 효과분석)

  • Yang, Nam Young;Lee, Mi Hyang
    • Journal of Korean Academy of Nursing Administration
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    • v.21 no.3
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    • pp.254-262
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    • 2015
  • Purpose: This study was done to apply failure mode & effect analysis (FMEA) to chemotherapy in order to reduce prescribing, dispensing and administering errors related to treatment and provide patients with a safe medical environment. Methods: A one group pre-post test design was used to verify the effects using the tool for FMEA in chemotherapy. Results: There was a statistically significant decrease in prescribing errors from 11.47% to 3.18%; administering errors decreased but they were not statistically significant. In a addition, there was no change in dispensing errors. Conclusion: The results show that FMEA removed risk factors that might occur during the process of chemotherapy and that it was an effective tool for prevention of negligent accident occurring in actual patients.

Shearing characteristics of slip zone soils and strain localization analysis of a landslide

  • Liu, Dong;Chen, Xiaoping
    • Geomechanics and Engineering
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    • v.8 no.1
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    • pp.33-52
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    • 2015
  • Based on the Mohr-Coulomb failure criterion, a gradient-dependent plastic model that considers the strain-softening behavior is presented in this study. Both triaxial shear tests on conventional specimen and precut-specimen, which were obtained from an ancient landslide, are performed to plot the post-peak stress-strain entire-process curves. According to the test results of the soil strength, which reduces from peak to residual strength, the Mohr-Coulomb criterion that considers strain-softening under gradient plastic theory is deduced, where strength reduction depends on the hardening parameter and the Laplacian thereof. The validity of the model is evaluated by the simulation of the results of triaxial shear test, and the computed and measured curves are consistent and independent of the adopted mesh. Finally, a progressive failure of the ancient landslide, which was triggered by slide of the toe, is simulated using this model, and the effects of the strain-softening process on the landslide stability are discussed.

Stress wave propagation in composite materials

  • Shen, Siyuan J.;Pfister, Jens C.;Lee, James D.
    • Structural Engineering and Mechanics
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    • v.11 no.4
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    • pp.407-422
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    • 2001
  • The linear constitutive relations and the failure criteria of composite materials made of thermoviscoelastic solids are presented. The post-failure material behavior is proposed and the dynamic finite element equations are formulated. However, a nonlinear term is kept in the energy equation because it represents the effect of the second law of thermodynamics. A general purpose nonlinear three-dimensional dynamic finite element program COMPASS is upgraded and employed in this work to investigate the interdependence among stress wave propagation, stress concentration, failure progression and temperature elevation in composite materials. The consequence of truthfully incorporating the second law of thermodynamics is clearly observed: it will always cause temperature rise if there exists a dynamic mechanical process.

Assessment of Carsington Dam Failure by Slope Stability and Dam Behavior Analyses (사면안정 해석과 댐 거동분석을 통한 Carsington Dam 파괴의 고찰)

  • 송정락;김성인
    • Proceedings of the Korean Geotechical Society Conference
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    • 1991.10a
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    • pp.87-102
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    • 1991
  • It has been reported that the failure of Carsington Dam in Eng1and occured due to the existence of a thin yellow clay layer which was not identified during the design work, and due to pre-existing shears of the clay layer. The slope stability analyses during the design work, which utilized traditional circular arc type failure method and neglected the existence of the clay layer, showed a safety factor of 1.4. However, the post-failure analyses which utilized translational failure mode considering the clay layer and the pre-existing shear deformation revealed the reduction of safety factor to unity. The post-failure analysis assumed 10。 inclination of the horizontal forces onto each slice based on the results of finite element analyses. In this paper, Bishop's simplified method, Janbu method, and Morgenstern-Price method were used for the comparison of both circular and translational failure analysis methods. The effects of the pre-existing shears and subsquent movement were also considered by varying the soil strength parameters and the pore pressure ratio according to the given soi1 parameters. The results showed factor of safefy 1.387 by Bishop's simplified method(STABL) which assumed circular arc failure surface and disregarding yellow clay layer and pre-failure material properties. Also the results showed factor of safety 1.093 by Janbu method(STABL) and 0.969 by Morgenstern-Price method(MALE) which assumed wedge failure surface and considerd yellow clay layer using post failure material properties. In addition, dam behavior was simulated by Cam-Clay model FEM program. The effects of pore pressure changes with loading and consolidation, and strength reduction near or at failure were also considered based on properly assumed stress-strain relationship and pore pressure characteristics. The results showed that the failure was initiated at the yellow clay layer and propagated through other zones by showing that stress and displacement were concentrated at the yel1ow clay layer.

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Effect of Wrinkling on Failure Behavior of Thin Membranes (얇은 막재에서 주름이 파괴거동에 미치는 영향)

  • Kim, Young-Ah;Woo, Kyeong-Sik
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.39 no.11
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    • pp.1005-1012
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    • 2011
  • In this paper, the effect of wrinkling on the failure behavior of thin membrane was studied using geometrically nonlinear shell element post-buckling analysis with global-local analysis strategy. In the analysis, double-edge notched and single-edge notched tensile specimen configurations were considered. The analyses were performed for both cases with allowing and suppressing the wrinkling deformation. The results were investigated focusing on the effect of wrinkle development on the variation of J-integral values at the cut tip. The effect of cut lengths and the specimen lengths were also systematically studied.

Effects of a relined fiberglass post with conventional and self-adhesive resin cement

  • Wilton Lima dos Santos Junior;Marina Rodrigues Santi;Rodrigo Barros Esteves Lins;Luis Roberto Marcondes Martins
    • Restorative Dentistry and Endodontics
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    • v.49 no.2
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    • pp.18.1-18.13
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    • 2024
  • Objectives: This study was conducted to evaluate the mechanical properties of relined and non-relined fiberglass posts when cemented to root canal dentin using a conventional dual-cure resin cement or a self-adhesive resin cement. Materials and Methods: Two types of resin cements were utilized: conventional and self-adhesive. Additionally, 2 cementation protocols were employed, involving relined and non-relined fiberglass posts. In total, 72 bovine incisors were cemented and subjected to push-out bond strength testing (n = 10) followed by failure mode analysis. The cross-sectional microhardness (n = 5) was assessed along the root canal, and interface analyses (n = 3) were conducted using scanning electron microscopy (SEM). Data from the push-out bond strength and cross-sectional microhardness tests were analyzed via 3-way analysis of variance and the Bonferroni post-hoc test (α= 0.05). Results: For non-relined fiberglass posts, conventional resin cement exhibited higher pushout bond strength than self-adhesive cement. Relined fiberglass posts yielded comparable results between the resin cements. Type II failure was the most common failure mode for both resin cements, regardless of cementation protocol. The use of relined fiberglass posts improved the cross-sectional microhardness values for both cements. SEM images revealed voids and bubbles in the incisors with non-relined fiberglass posts. Conclusions: Mechanical properties were impacted by the cementation protocol. Relined fiberglass posts presented the highest push-out bond strength and cross-sectional microhardness values, regardless of the resin cement used (conventional dual-cure or self-adhesive). Conversely, for non-relined fiberglass posts, the conventional dual-cure resin cement yielded superior results to the self-adhesive resin cement.

Renal function is associated with prognosis in stent-change therapy for malignant ureteral obstruction

  • Yoon, Ji Hyung;Park, Sejun;Park, Sungchan;Moon, Kyung Hyun;Cheon, Sang Hyeon;Kwon, Taekmin
    • Investigative and Clinical Urology
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    • v.59 no.6
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    • pp.376-382
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    • 2018
  • Purpose: The authors performed this study to investigate the risk factors for predicting stent failure and to evaluate its impact on prognosis. Materials and Methods: Between January 2002 and March 2017, we retrospectively reviewed 117 consecutive patients who underwent retrograde ureteral stenting and exchanging at least once every 3 months for malignant ureteral obstruction. The patients were classified according to their pre-stenting chronic kidney disease (CKD) stage. The factors affecting stent failure were analyzed using a logistic regression model. Overall survival (OS) was estimated, and the prognostic significance of each variable was estimated using Cox proportional-hazards regression modeling. Results: Before stenting, 91 patients were CKD stages 1-3 and 26 patients were CKD stages 4-5. These two groups differed significantly only in pre-stenting estimated glomerular filtration rate (eGFR), bilateral obstruction, and pre-stenting pyuria. Among the 117 patients, stent failure occurred in 30 patients (25.6%), and there were no differences between the groups. Pre-stenting pyuria and post-stenting complications were significant predictors of stent failure. There were 79 deaths in total, including 56 in the CKD stages 1-3 group and 23 in the CKD stages 4-5 group. In the multivariate analysis predicting patient OS, pre-stenting eGFR and post-stenting disease progression were significant factors. Conclusions: Internal ureteral stenting was effective for maintaining renal function in malignant ureteral obstruction. However, it did not restore renal function, which is related to the prognosis of the patients. Therefore, to improve patients' renal function and prognosis, patients who require stenting must be quickly recognized and treated.