• Journal of Acupuncture Research
• /
• v.36 no.3
• /
• pp.147-153
• /
• 2019

Background: The aim of this study was to investigate the safety and analgesic effects of Datura Flos pharmacopuncture (DFP). Methods: The analgesic effects of DFP were assessed using mechanical (hot plate), chemical (formalin test), and thermal (von Frey filament test) pain tests. Forty male Sprague Dawley rats were assigned randomly into DFP (75 mg/kg, 150 mg/kg), lidocaine 0.5%, or normal saline group for treatment on Kl3. Gross pathology, histopathology, biochemistry and hematology were performed. Results: In the hot plate test, DFP at a high dose (HDDFP; 150 mg/kg) produced a significant analgesic effect, at 10 and 20-minutes post injection (p < 0.01). Low dose DFP (LDDFP; 75 mg/kg) also showed an analgesic effect at 10 minutes post injection (p < 0.01). In the formalin test, HDDFP produced an analgesic effect, for 0-10 and 10-20 minutes (p < 0.01) post treatment, whereas LDDFP showed analgesic effects between 10-20 minutes (p < 0.05). In the von Frey filament test, DF-H produced an analgesic effect, 10 (p < 0.01) and 20 minutes post treatment (p < 0.05). LDDFP showed analgesic effect at 10 minutes (p < 0.05). In the acupuncture response test, HDDFP produced an analgesic effect at 10 minutes post treatment (p < 0.05). DF-H did not cause any anatomical changes to the liver or kidney and there were no abnormalities in biochemistry or hematology. Conclusion: DF-H was not toxic and provided short term analgesia, suggesting it may be useful in the management of pain.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.31 no.1
• /
• pp.38-49
• /
• 2021

Objectives: This study was conducted to analyze the impact of safety/health managers' experience of trauma case on their post traumatic stress disorder and the mediation effects of job stress and the moderated mediation effects of social support. Method: Using a structured questionnaire, data were collected from 241 workplace safety/health managers with experience in trauma case. The collected data were analyzed using SPSS(IBM. Ver.26.0) and verified through SPSS PROCESS Macro (Ver. 3.4). Results: The trauma case experience and the job stress, which is a mediation variable, had a statistically significant positive effect on post-traumatic stress disorder, and the job stress had a positive mediation effect in the relationship between the trauma case experience and post-traumatic stress disorder. Social support had a statistically significant negative moderation effect in the relationship between the trauma case experience and job stress; social support had a moderated mediation effect on the indirect effect of a job stress on the post-traumatic effect through a trauma case experience. Conclusion: The above findings suggest that work-related job stress management is important in order to reduce safety/health managers' post-traumatic stress disorder caused by the experience of trauma case, and that social support is essential to reduce the job stress, which can later be used as a basis for further studies.

• Journal of The Korean Association For Science Education
• /
• v.14 no.1
• /
• pp.70-84
• /
• 1994

This study tried to find the effect to cognitive structure upon the momentum effect. The previous studies showed that the momentum effect is influenced by students' cognitive levels and the abstractness of test items. The cognitive structure is examined by cognitive level and cognitive style. Cognitive levels and cognitive styles are determined by GALT and GEFT respectively. The research method used in this study is time series design. The period is 50 days. The period is divided into "pre-test", "intervention-test", "post-test". Pre-test period is 5 days and in this period class instruction does not exist Intervention-test period is 30 days and in this period class instruction exist Post-test period is 15 days and in this period class instruction does not exist. Field independent students showed longer momentum effect than field dependent students. Formal level students showed less ratio of decrease on post-test than nonformal level students. Momentum effects is not artifact but the essential characteristics of science study.

• Journal of The Korean Dental Society of Anesthesiology
• /
• v.14 no.1
• /
• pp.49-56
• /
• 2014

Background: Propofol (2.6-diisopropylphenol) is a widely used intravenous anesthetic agent for the induction and maintenance of anesthesia during surgeries and sedation for ICU patients. Propofol has a structural similarity to the endogenous antioxidant vitamin E and exhibits antioxidant activities.13) However, the mechanism of propofol on hypoxia/reoxygenation (H/R) injury has yet to be fully elucidated. We investigated how P-PostC influences the autophagy and cell death, a cellular damage occurring during the H/R injury. Methods: The groups were randomly divided into the following groups: Control: cells were incubated in normoxia (5% CO2, 21% O2, and 74% N2) without propofol treatment. H/R: cells were exposed to 24 h of hypoxia (5% CO2, 1% O2, and 94% N2) followed by 12 h of reoxygenation (5% CO2, 21% O2, and 74% N2). H/R + P-PostC: cells post-treated with propofol were exposed to 24 h of hypoxia followed by 12 h of reoxygenation. 3-MA + P-PostC: cells pretreated with 3-MA and post-treated propofol were exposed to 24 h of hypoxia followed by 12 h of reoxygenation Results: The results of our present study provides a new direction of research on mechanisms of propofol-mediated cytoprotection. There are three principal findings of these studies. First, the application of P-PostC at the onset of reoxygenation after hypoxia significantly increased COS-7 cell viability. Second, the cellular protective effect of P-PostC in H/R induced COS-7 cells was probably related to activation of intra-cellular autophagy. And third, the autophagy pathway inhibitor 3-MA blocked the protective effect of P-PostC on cell viability, suggesting a key role of autophagy in cellular protective effect of P-PostC. Conclusions: These data provided evidence that P-PostC reduced cell death in H/R model of COS-7 cells, which was in agreement with the protection by P-PostC demonstrated in isolated COS-7 cells exposed to H/R injury. Although the this study could not represent the protection by P-PostC in vivo, the data demonstrate another model in which endogenous mechanisms evoked by P-PostC protected the COS-7 cells exposed to H/R injury from cell death.

• International Journal of Industrial Entomology and Biomaterials
• /
• v.16 no.2
• /
• pp.61-66
• /
• 2008

In this paper, the regenerated silk fibroin (SF)/nylon 6 blend filaments were fabricated using wet spinning technique and the effect of coagulant on the post drawing and morphology of blend filaments was investigated. In the result of wet spinnability, methanol, acetone, DMF, and THF showed relatively good coagulation strength and fiber formation for the regenerated SF. On the contrary, they did not exhibit strong enough to produce a uniform nylon 6 filament due to the lack of coagulation strength. In the examination of post drawing performance, methanol showed the highest maximum draw ratio of the blend filament over all blend ratios. The maximum draw ratio of SF/nylon 6 blend filaments decreased with the reduction of SF content regardless of type of coagulant. SEM observation showed the consistent result with that of post-drawing performance. As SF content decreased, the uniform and regular structure was changed to irregular one. In particular, the severe macro-phase separation between SF and nylon 6 could be detected in the 50/50 SF/nylon 6 blend filaments coagulated in methanol and THF.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2002.10a
• /
• pp.659-662
• /
• 2002

SL(Stereolithography) part is made by piling up thin layers which causes the stair stepping effect at the surface of SL parts. This effect brings about excessive surface roughness and requires additional post-process finishing such as abrasive techniques that are detrimental to part geometry and time consuming. Hence a wax coating and grinding post-process is proposed to improve the surface quality of SL part. The wax that has suitable properties for the proposed post-process is coated all over the part surface. By grinding the thin layer of coated on the SL part only, the surface roughness can be improved without any damage on the part. From the experimental results, This approach is considered to be very practical fur die casting with RT(Rapid Tooling) techniques.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.20 no.5
• /
• pp.319-329
• /
• 2016

The Eradi Quake System (EQS) is a seismic isolation bearing system designed to minimize forces and displacements experienced by structures subjected to ground motion. The EQS dissipates seismic energy through friction of Poly Tetra Fluoro Ethylene (PTFE) disk pad. In general, a force-displacement relationship of EQS has post yield stiffness hardening during large inelastic displacement. In this study, seismic responses of seismically isolated nuclear power plant (NPP) subjected to design basis earthquake (DBE) and beyond design basis earthquakes (150% DBE and 167% DBE) are compared considering the post yield stiffness hardening effect of EQS. From the results, it can be observed that if the post-yield stiffness hardening effect of EQS is increased, the displacement response of EQS is reduced, and the acceleration and shear responses of containment structures of NPP is increased.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
• /
• v.22 no.2
• /
• pp.114-118
• /
• 2009

PVA (polyvinyl alcohol) brush cleaning method is a typical cleaning method for semiconductor cleaning process especially post-CMP cleaning. PVA brush contacts with the wafer surface and abrasive particle, generating the contact rotational torque of the brush, which is the removal mechanism. The brush rotational torque can overcome theoretically the adhesion force generated between the abrasive particle and wafer by zeta potential. However, after CMP (chemical mechanical polishing) process, many particles remained on the wafer because the brush was contaminated in previous post-CMP cleaning step. The abrasive particle on the brush redeposits to the wafer. The level of the brush contamination increased according to the cleaning run time. After cleaning the brush, the level of wafer contamination dramatically decreased. Therefore, the brush cleanliness effect on the cleaning performance and it is important for the brush to be maintained clearly.

• Journal of the Korean Society for Precision Engineering
• /
• v.21 no.9
• /
• pp.196-203
• /
• 2004

SL(Stereolithography) part is made by piling up thin layers which causes the stair stepping effect at the surface of SL parts. The effect brings about excessive surface roughness and cuts down the merits of using SL part. Hence, additional post-machining finishing such as traditional grinding is required. But the traditional post-machining is detrimental to part geometry and time consuming. In this study, therefore, a paraffin coating and grinding post-machining is newly proposed to improve the surface quality of SL fart. The paraffin which has suitable properties for the proposed post-machining is coated all over the part surface. By grinding the only over-coated paraffin based on boundary of the SL part surface, the surface roughness can be improved without any damage on the part. Also, it is verified that SL part finished by the proposed post-machining process can be applied for rapid tooling as pattern through manufacturing silicon rubber molding and casting test.

• Coupled systems mechanics
• /
• v.8 no.5
• /
• pp.459-471
• /
• 2019

This paper presents post-buckling analysis of a functionally graded beam under hygro-thermal effect. The material properties of the beam change though height axis with a power-law function. In the nonlinear kinematics of the post-buckling problem, the total Lagrangian approach is used. In the solution of the problem, the finite element method is used within plane solid continua. In the nonlinear solution, the Newton-Raphson method is used with incremental displacements. Comparison studies are performed. In the numerical results, the effects of the material distribution, the geometry parameters, the temperature and the moisture changes on the post-buckling responses of the functionally graded beam are presented and discussed.