• Korean Journal of Poultry Science
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• v.17 no.4
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• pp.255-268
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• 1990

This study was carried out to investigate the time-trends of genetic parameters of the dosed flock population which selected for improving egg production. Data for two layer pure lines, Line-W (Single Comb White Leghorn) and Line-B (brown layer) which have been maintained at the Mani Breeding Farm were collected from 1980 to 1985 during 5 generations. The effective number of parents per generation ranged from 148 to 366 in Line-W and 85 to 355 in Line-B, and the cumulative expected inbreeding coefficients during 5 generations of selection were 15％ and 1.6％. So inbreeding could not be considered a critical factor on estimating the genetic parameters, heritabilities and genetic correlations Heritabilities of EN 300 and EN 400, primary two selected traits were significantly decreased during 5 generations but the estimates of the other 03its not showed the consistent decreasing pattern significantly. No time trends of probable consequence were evident in the genetic correlation coefficients of the traits studied. The reason for that situation was attributed to the fact that selection was conducted for multiple objectives and the relative importance of selection for the studied traits were not consistent by generations.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7523-7527
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• 2015

Background: Pediatric acute lymphoblastic leukemia (pALL) patients at King Abdulaziz Medical City represent a pure Saudi Arabian population. ETV6-RUNX1 positive pALL patients have good prognosis as compared to ETV6-RUNX1 negative counterparts. Therefore, frequencies of these two patient groups have a huge consideration in treatment strategies of pALL in a given population. Different geographical locations have been reported to have different frequencies of ETV6-RUNX1 ranging from 10% in Southeast Asia to 30% in Australia. Aim: Therefore, the objective of this study was to establish the ETV6-RUNX1 status of Saudi Arabian pALL patients and its association with clinical parameters and early remission. Materials and Methods: Clinical parameters and ETV6-RUNX1 status (using FISH technique) of pALL patients attending the Pediatric Oncology Clinic, King Abdulaziz Medical City, Riyadh from 2006 to 2011 were studied. Comparisons between ETV6-RUNX1 positive and negative groups were accomplished using chi-square test or Fisher's exact test. All statistical analyses were performed using SAS version 9.2 (SAS Institute, Inc., Cary, NC). Results: Out of 54 patients, 33 were male and 21 were females (ratio 1.57:1). B- and T-cell lineages were found in 47 (87%) and 7 (13%) patients respectively. Only 5 (9.3%) patients were ETV6-RUNX1 positive while 49(80.7%) were ETV6-RUNX1 negative. All ETV6-RUNX1 patients (100%) were of B-cell lineage and 80% (4/5) were in the 3-7 year age group. None of the ETV6-RUNX11 patients had ${\geq}5%$ blasts (no remission) at day 14 as compared with 9% in the ETV6-RUNX1 negative group (Figure 1). Conclusions: Frequency of ETV6-RUNX1 positive patients (less than 10%) in our pALL patients is much lower than reported for most European countries, North America, Australia and Japan while it is in accordance with ETV6-RUNX1 frequencies from Egypt (11.6%), Pakistan (10%), Spain (2%) and India (5-7%). This shows ethnic differences in genetics of pALL as well as higher frequencies of ETV6-RUNX1 positive pALL mostly in more industrialized countries, probably due to some industrial pollutants or westernized lifestyle.

• Journal of Korean Society of Forest Science
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• v.102 no.2
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• pp.264-271
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• 2013

Mating system parameters were estimated in a natural population of Pinus koraiensis which was located at Gwongeumseong in Mt. Seorak, South Korea. The estimated parameters from allozyme were as follows: 0.882 of multilocus outcrossing rates($t_m$), 0.881 of singlelocus outcrossing rates($t_s$), 0.368 of correlated paternity($r_p$), and 2.7 of number of effective pollen contributors. The estimated parameters from cpSSR markers were as follows: 0.831 of average of outcrossing rates and 12.4 of the average number of effective pollen contributors. The average outcrossing rate from two genetic markers was 0.857, which was similar to those estimated in other conifer species. More number of potential pollen contributors was estimated from cpSSR marker analysis compared with that estimated from allozyme marker analysis. This result sugges$t_s$ that cpSSR markers may be more useful than allozyme markers for identifying potential pollen contributors in the analysis of mating system.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.14 no.3
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• pp.184-192
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• 2021

Domestic agriculture is facing real problems, such as a decrease in the population in rural areas, a shortage of labor due to an aging population, and increased risks due to the deepening of climate change. Smart farming technology is being developed to solve these problems. In the development of smart agricultural technology, irrigation control plays an important role in creating an optimal growth environment and is an important issue in terms of environmental protection. This paper is about the study of collecting and analyzing the rhizosphere environmental data of domestic paprika farms for the purpose of improving the quality of crops, reducing production costs, and increasing production. Irrigation control modeling presented in this paper Control modeling is to graphically present changes in a medium weight, feed, and drainage due to regional climatic features. To derive the graph, the parameters were determined through data collection and analysis, and the suggested irrigation control modeling method was applied to the collected rhizosphere environmental data to control irrigation in 6 regions (Gangwon-do, Chungnam, Jeonbuk, Jeonnam, Gyeongbuk, and Gyeongnam). The parameters were obtained and graphs were derived from them. After that, a study was conducted to analyze the derived parameters to verify the validity of the irrigation control modeling method and to correlate them with climatic features (average temperature and precipitation).

• Physical Therapy Rehabilitation Science
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• v.2 no.2
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• pp.81-86
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• 2013

Objective: The objective of this study was to investigate the feasibility and effects of balance training using a newly developed elastic band orthosis (aider) for improvement of mobility and balance in chronic stroke patients. Design: Cross-sectional study. Methods: Ten patients with chronic hemiplegia participated in this study. There were six males and four females; two patients had right hemiplegia and eight had left hemiplegia. This study investigated the effect of the elastic band orthosis on balance and gait ability compared with bare foot condition. Gait parameters were measured using the opto-gait system for analysis of the spatial and temporal parameters of walking in stroke patients. In addition, balance ability in stroke patients was evaluated using the Timed Up and Go (TUG) and Berg Balance Scale (BBS). Results: This study investigated the effect of the elastic band orthosis on balance compared with bare foot condition. The TUG and BBS showed significant improvement with use of the elastic band orthosis (p<0.05). Use of the Elastic band orthosis resulted in significantly improved velocity, cadence, less-affected step length, less-affected stride length, and less-affected single limb support in stroke patients (p<0.05). Conclusions: We demonstrated a significant improvement in dynamic balance and gait ability in chronic stroke patients using the elastic band orthosis. This orthosis may aid in prevention of spastic foot drop, leading to improvement of walking ability.

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.2
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• pp.257-260
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• 2003

A total of 135 F2 finishing pigs (65 barrows and 69 gilts) from resource population (Large White${\times}$Meishan) were slaughtered at about 87.8 kg BW. Contents of inosine acid (IMP) and carnine (HR) in muscle were assayed by HLPC and genetic parameters for IMP content and HR content were estimated using full sibs model. There was significant sex effect on IMP content(p<0.05), $3.561{\pm}0.077mg/g$ for gilt and $3.287{\pm}0.085mg/g$ for barrow. Heritability estimates for IMP and HR content were 0.127 and 0.357, respectively. The phenotypic correlation between IMP content and HR was 0.335, pH (A) 0.024, water lose rate (WLR) -0.069, intramuscular fat (IMF) -0.214, average marbling score (MARB) -0.143, average backfat measurements (AVBF) -0.084 and average color value (CV) -0.156, respectively. The result indicated that inosine acid content in meat might be retained or slightly improved by reducing backfat depth in pig breeding.

• Physical Therapy Korea
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• v.11 no.3
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• pp.19-24
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• 2004

The purposes of this study were to analyze gait patterns of patients with chronic lumboscaral radiculopathy and to investigate gait parameters which can reflect a functional deficit in relation to the level of lumbosacral radiculopathy. The study population consisted of 25 patients of chronic lumbosacral radiculopathy and 25 healthy control subjects. Conventional physical examinations and three-dimensional gait analyses were performed on all participants. The data were analyzed using an independent sample t-test. The results were as follows: (1) In the patients' group, cadence, walking velocity, stride length and double support time were less than in the control group (p<.05). (2) In the patients' group, maximum flexion of hip, maximum flexion of loading response, maximum flexion of swing phase on the knee and maximum plantar flexion of pre-swing were less than the control group (p<.05). Using three-dimensional gait analysis, we could identify specific gait parameters to reflect a functional deficit related to the level of lumbosacral radiculopathy.

• Environmental Mutagens and Carcinogens
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• v.22 no.4
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• pp.243-247
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• 2002

Prolonged exercise is known to increase steady-state serum high-density lipoprotein cholesterol (HDL-cholesterol) and apolipoprotein AI(apo AI) concentrations. We investigated the effect of adaptation to endurance exercise on the association of the genetic polymorphism in the apo AI gene with these biochemical parameters. 108 male subjects were randomly selected from a group of elite athletes, and 65 male samples used as sedentary control group from Korean general population. The genetic polymorphism in the apo AI gene locus was detected by polymerase chain reaction(PCR) and DNA digestion with Msp I restriction endonuclease. The genotype frequency for the Msp I RFLP was significantly different between the elite athletes and sedentary controls(P<0.05). There were, however, no significant associations between the Msp I RFLP of the apo AI gene and the biochemical parameters in elite athletic group. Therefore, our findings indicate that the Msp I RFLP of the apo AI gene was not associated with the serum apo AI and HDL-cholesterol concentrations in Korean male elite athletes.

• Journal of Korean Society for Quality Management
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• v.30 no.3
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• pp.203-236
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• 2002

Environmental Performance Evaluation(EPE) is a key process of Corporate Environmental Management. This paper presents the results of an empirical survey on the status of current practices in EPE of Korean firms. Based on a corporate environmental management(CEM) model, which is initially developed by Hibbitt and Kamp-Roelands(2001) and modified in terms of EPE, the survey is peformed on the population of Korean firms, which are composed of firms certified as "environmentally friendly" by Korean government and/or certified under Is014001, and compares its results with those of Europe's. Although the relatively low response rate and some methodological limitations makes us be cautious about the interpretation, the results shows many interesting aspects of the current states of Korean firms' EPE practices. That is, the levels of EPE implementation in the environmentally-leading companies of Korea are almost the same as that of European companies, I. e., in the-final-part-of-developing-stage (3rd stage) level of the CEM model. It is also shown that as In Europe's case, Korean firms are also moving slower in external relationships than in internal control and management, are more developed in the parameters like environmental policy, Internal control, Information system, which are requirements of certification under Is014001, than in parameters like life cycle analysis and full cost accounting, which requires more research efforts, etc.orts, etc.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8599-8604
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• 2016

Ovarian cancer is the main cause of mortality in gynecological malignancy and extensive studies have been conducted to study the underlying molecular mechanisms. The BRCA2 gene is known to be an important tumor suppressor in ovarian cancer, thereby BRCA2 alterations may lead to cancer progression. However, the BRCA2 gene is rarely mutated, and loss of function is suspected to be mediated by epigenetic regulation. In this study we investigated the methylation status and gene expression of BRCA2 in ovarian cancer patients. Ovarian cancer pateints (n=69) were recruited and monitored for 54 months in this prospective cohort study. Clinical specimens were used to study the in situ expression of aberrant BRCA2 proteins and the methylation status of BRCA2. These parameters were then compared with clinical parameters and overall survival rate. We found that BRCA2 methylation was found in the majority of cases (98.7%). However, the methylation status was not associated with protein level expression of BRCA2 (49.3%). Therefore in addition to DNA methylation, other epigenetic mechanisms may regulate BRCA2 expresison. Our findings may become evidence of BRCA2 inactivation mechanism through DNA methylation in the Indonesian population. More importantly, from multivariate analysis, BRCA2 expression was correlated with better overall survival (HR 0.32; p=0.05). High percentage of BRCA2 methylation and correlation of BRCA2 expression with overall survival in epithelial ovarian cancer cases may lead to development of treatment modalities specifically to target methylation of BRCA genes.