• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 추계국제학술대회
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• pp.15-15
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• 2020

In an internal document, CORONA-VIRUS DISEASE 2019 (COVID-19) PLAN, release developed stated that "on January 22, 2020, Palau Ministry of Health activated its emergency operations center, and since then has prepared and put in place measures in response to this global pandemic." The actions eventually led to the closure of most flights coming into Palau as a method to protect its population. The population of is at high risk with COVID19 due to the very elevated rate of NCD's, as well as the limited access to proper testing and treatment facilities. Increased use of traditional medicines in the population has reduced the co-morbidities by reducing risk factors. Furthermore, the expansion of tradtional NCD therapies, especially that of DAK reduce pressure due to obesity and diabetes therefore allowing for unimpaired immune systems to combat deadly infectious diseases such as COVID19.

• Animal Bioscience
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• 제34권4호
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• pp.525-532
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• 2021

Objective: Old World camels are a valuable genetic resource for many countries around the world due to their adaptation to the desert environment. At present, Old World camels have encountered the challenge of unprecedented loss of genetic resources. Through our research, we would reveal the population structure and genetic variation in Old World camel populations, which provides a theoretical basis for understanding the germplasm resources and origin and evolution of different Old World camel populations. Methods: In the present study, we assessed mtDNA control region sequences of 182 individuals from Old World camels to unravel genetic diversity, phylogeography, and demographic dynamics. Results: Thirty-two haplotypes confirmed by 54 polymorphic sites were identified in the 156 sequences, which included 129 domestic and 27 wild Bactrian camels. Meanwhile, 14 haplotypes were defined by 47 polymorphic sites from 26 sequences in the dromedaries. The wild Bactrian camel population showed the lowest haplotype and nucleotide diversity, while the dromedaries investigated had the highest. The phylogenetic analysis suggests that there are several shared haplotypes in different Bactrian camel populations, and that there has been genetic introgression between domestic Bactrian camels and dromedaries. In addition, positive values of Tajima's D and Fu's Fs test demonstrated a decrease in population size and/or balancing selection in the wild Bactrian camel population. In contrast, the negative values of Tajima's D and Fu's Fs test in East Asian Bactrian camel populations explained the demographic expansion and/or positive selection. Conclusion: In summary, we report novel information regarding the genetic diversity, population structure and demographic dynamics of Old World camels. The findings obtained from the present study reveal that abundant genetic diversity occurs in domestic Bactrian camel populations and dromedaries, while there are low levels of haplotype and nucleotide diversity in the wild Bactrian camel population.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제7권1호
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• pp.45-55
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• 2001

In the 20th Century, the genera1 hospitals in Korea had changed in Qualitative and Quantitative aspects, The former would include such as the development of medical skills, equipments, and network system, The expansion of hospital space, increased numbers of hospitals and greater demands of medical attention from the public would be included in the latter, These various changes have been related to external forces such as the growth of the population, the changes in medical policy, the growth of G.N.P, the continuing discovery of new illnesses, the changes in architecture policy, and et cetera. Particularly, the hospitals built in 1970's and 80's have been expanded and renovated to cover the shortage of space, aged facilities, and the changes in hospital atmosphere. Thus, we hope that this study would provide appropriate data for master plans for new medical facilities as well as expansion and renovation data for old ones.

• 응용통계연구
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• 제20권2호
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• pp.281-290
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• 2007

유한 모집단에서 총계 추정에는 표본의 각 관측값으로 만들어지는 선형 추정량이 사용되는데 이때 사용되는 가중치는 표본 추출 확률의 역수를 사용한 기본 가중치를 모집단 전체에서 얻어지는 보조 정보를 이용하여 보정한 형태로 종종 사용된다. 이렇게 보정된 가중치를 사용한 추정량은 그렇지 않은 추정량보다 효율이 더 좋아질 수 있는 장점이 있으나 이러한 경우 분산 추정은 더 어려워지게 된다. 본 연구에서는 보정된 가중치를 사용한 추정량의 분산 추정을 다룬다. 가중치 보정의 일반적인 형태를 밝히고 이 경우 가중치 보정항은 유한개의 장애 모수(nuisance parameter)의 함수로 나타낼 수 있으므로 이 장애 모수에 대한 테일러 전개를 사용한 분산 추정식을 구한다. 이렇게 구현된 분산 추정식은 기존의 가중치 보정 추정량뿐만 아니라 보다 일반적인 경우에서도 적용될 수 있다는 장점이 있다. 몇가지 응용 사례와 모의 실험 결과를 소개한다.

• 보건행정학회지
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• 제14권4호
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• pp.21-47
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• 2004

There is general agreement that the Korean health care delivery system has two basic structural problems. One is the limited capacity and role of public hospitals, and the other is the absence of functional differentiation and referral arrangement between the clinics and hospitals of various technological sophistication levels. This study is intended to make an empirical observation of the system's growth process from the viewpoint of the population ecology model of organizations so as to understand the background of these problems and to find out ways of approaching them. As predicted from the population ecology model of organizations, all the types of medical care facilities have expanded in response to the environmental changes for the past three decades or so, and the differences in the extent and pattern of expansion among the types are related to what have taken place in the environment. These findings suggest that the efforts for reforming the health care delivery system should be directed not only to medical care institutions but also to the environmental context under which they function. It is believed that the usefulness of the population ecology perspective on organizations for studying the health care delivery system has been demonstrated. Thus further studies along this line based upon more strict design would improve systematic understanding of the system that is needed for developing policy approaches needed to increase its effectiveness.

• 상하수도학회지
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• 제27권5호
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• pp.661-669
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• 2013

River-water quality has been greatly improved during past several decades with the extraordinary expansion for the wastewater treatment capacities by the government. Research aims to select the priority restoration streams based on the chronicle data for tributaries in Geumgang watershed as the main stream area in the Chungchungnamdo province. The quality of BOD, phosphorus and percent of sewered population on 15 branch streams were compared by the grouping methods. The results of group D streams by category I that exceed 3.0 mg/L for BOD and 0.1 mg/L for phosphorus were Seuksung, Ganggyung and Bangchuk stream. The results of group D streams by category II that exceed 3.0 mg/L for BOD and less than 63.5 % of average percent of sewered population were Ganggyung, Gilsan, Bangchuk and Seuksung stream. The final results of selected streams drawn by the chronicle data which exceeded the standard quality and lower than the average percent of sewered population were Seoksung, Gangeyung and Bangchuk stream. The pollution of rivers in the down streams were more serious than in the upper streams. Their watersheds have to be improved river water quality, especially to extend sewer systems as well as wastewater treatment facilities.

• Asian-Australasian Journal of Animal Sciences
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• 제25권9호
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• pp.1223-1228
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• 2012

The population sizes of three Korean indigenous cattle populations have been drastically reduced over the past decades. In this study, we examined the extent to which reduction in populations influenced genetic diversity, population structure and demographic history using complete mitochondrial DNA (mtDNA) control region sequences. The complete mtDNA control region was sequenced in 56 individuals from Korean Black (KB), Jeju Black (JEB) and Korean Brindle (BRI) cattle populations. We included 27 mtDNA sequences of Korean Brown (BRO) from the GenBank database. Haplotype diversity estimate for the total population was high (0.870) while nucleotide diversity was low (0.004). The KB showed considerably low nucleotide (${\pi}$ = 0.001) and haplotype (h = 0.368) diversities. Analysis of molecular variance revealed a low level of genetic differentiation but this was highly significant (p<0.001) among the cattle populations. Of the total genetic diversity, 7.6% was attributable to among cattle populations diversity and the rest (92.4%) to differences within populations. The mismatch distribution analysis and neutrality tests revealed that KB population was in genetic equilibrium or decline. Indeed, unless an appropriate breeding management practice is developed, inbreeding and genetic drift will further impoverish genetic diversity of these cattle populations. Rational breed development and conservation strategy is needed to safeguard these cattle population.

• 한국동물생명공학회지
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• 제34권2호
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• pp.86-92
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• 2019

The aim of this study was to investigate effects of hyaluronidase during IVM on oocyte maturation, oxidative stress status, expression of cumulus expansion-related (PTX, pentraxin; GJA1, gap junction protein alpha 1; PTGS2, prostaglandin-endoperoxide synthase 2) and fatty acid metabolism-related (FADS1, delta-6 desaturase; FADS2, delta-5 desaturase; PPARα, peroxisome proliferator-activated receptor-alpha) mRNA, and embryonic development of porcine oocytes. The cumulus-oocyte complexes (COCs) were incubated with 0.1 mg/mL hyaluronidase for 44 h. Cumulus expansion was measured at 22 h after maturation. At 44 h after maturation, nuclear maturation, intracellular glutathione (GSH) and reactive oxygen species (ROS) levels were measured. Gene expression in cumulus cells was analyzed using real time PCR. The cleavage rate and blastocyst formation were evaluated at Day 2 and 7 after insemination. In results, expansion of cumulus cells was suppressed by treatment of hyaluronidase at 22 h after maturation. Intracellular GSH level was reduced by hyaluronidase treatment (p < 0.05). On the other hand, hyaluronidase increased ROS levels in oocytes (p < 0.05). Only PTGS2 mRNA was enhanced in COCs by hyaluronidase (p < 0.05). Population of oocytes reached at metaphase II stage was higher in control group than hyaluronidase treated group (p < 0.05). Both of cleavage rate and blastocyst formation were higher in control group than hyaluronidase group (p < 0.05). Our present results showed that developmental competence of porcine oocytes could be reduce by hyaluronidase via inducing oxidative stress during maturation process and it might be associated with prostaglandin synthesis. Therefore, we suggest that suppression of cumulus expansion of COCs could induce oxidative stress and decrease nuclear maturation via reduction of GSH synthesis and it caused to decrease developmental competence of mammalian oocytes.

• 토지주택연구
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• 제2권3호
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• pp.259-268
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• 2011

Space extension and the increase of the number of households are helpful to raise business value of the remodeling through the renovation of apartment houses that is required by residents of new cities and large-scaled apartment. However, in the case of accepting this demand, it could have a bad influence on the landscape of a complex in terms of the structure of apartment houses and the safety of construction and urban planning, and a problem occurs in the aspect of fairness for reconstruction. For the study, the current status related to the remodeling system through laws, related articles since 2000 and research data was analyzed. In addition, the individual quantitative analysis was conducted in the four aspects to judge whether households expansion for remodeling is plausible:1) Statistical data to comprehend the changes of population and social structure 2) Survey data of floor space index and the building-to-land ratio of new cities at the intial stage for the review of the effect of architectural planning and urban environment 3) Surveys of experts on structural safety in order to judge whether the demand of expansion is accepted or not. 4) Quantitative analysis of each item to compare fairness with reconstruction. Therefore, this study is intended to understand problems of the remodeling system that is currently operated. Moreover, it will be further reviewed that the expansion of households is feasible through the permission of expansion and it will be discussed that the revitalization of the apartment remodeling has a positive impact on the residential environment.

• 보건행정학회지
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• 제19권1호
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• pp.81-96
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• 2009

The expansion of long-term care hospitals (LTCHs) is expected to contribute to meeting the long-term care needs of the elderly with chronic diseases in a rapidly aging society. It is also expected to increase efficiency of health resource use and decrease elderly health expenditures by transferring patients from acute care hospitals (ACHs) to LTCHs. This study aimed to empirically examine how the expansion of LTCHs had influences on the length of hospitalization of the elderly in ACHs. Panel regression analysis was employed as an analytic tool using data of the National Health Insurance and the National Statistical Office from 2002 to 2006. The expansion of LTCHs was measured as location quotient (LQ) of LTCHs, denoting the share of LTCHs in a large city or province relative to the share of LTCHs at the national level. In addition, per capita GRDP (gross regional domestic product) and the proportion of population over 65 were included as control variables. The main findings are as follows. First, it was observed that LQ of LTCHs showed a statistically significant negative association with the length of hospitalization of the elderly in ACHs. Second, the negative correlation was evident among general hospitals with over 100 beds while it was not among hospitals with less than 100 beds. Third, LQ of LTCHs had more influences among the elderly over 85. In conclusion, the expansion of LTCHs seems to contribute to decrease in the inpatient cost of the elderly in ACHs and to increase efficiency in the utilization of health resources.